• Therapeutic Science for Rehabilitation
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• v.3 no.2
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• pp.71-81
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• 2014

Objective: The purpose of this study is to ob serve effects of CPM(Continuous Passive Motion) on hand functional and upper-extremity muscular strength rehabilitation for stroke patients. Method: Objects of this study, three patients have the symptoms of hemiplegia due to stroke. These are acute patients, within a 18 months after treatment and correspond in Brunnstrom stage 4~6. This study used single subject (A-B) design for three patients with a stroke and the effect of CPM was measured using Jebsen-Taylor hand function test, Purdue Pegboard test, hand muscular strength test. They received CPM for 3 weeks, 2 per day, 30 minutes for each, total 30 times. Results: Two patients' results of fingertip grip test in hand strength measurements did not change. Results of Jebsen-Taylor hand function test, Purdue Pegboard test and other hand muscular strength test were improved. To validate statistical results nonparametric statistical method, Wilcoxon signed ranks test was performed. P-Values are greater than 0.05 so difference between be fore and after treatment is not statistically significant result. Conclusion: Despite of limitation of short program period and fewer participants, CPM which has been conducted for stroke patients showed the effect on improvement of hand function and muscle strength. This study shows that CPM which is mainly used to treate lower-extremity rehabilitation can be use to improve performance of hand function and strength for patients with stroke.

• Journal of Convergence for Information Technology
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• v.12 no.2
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• pp.174-183
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• 2022

This study was conducted to investigate the effect of the active exercise program using sling on the pain and balance of total knee replacement patients. Subjects were 20 patients who received total knee replacement and are hospitalized, 10 patients in each group were randomly assigned to a group (CPM group) that applied only CPM (Continuous passive motion) and a group (CSG) that combined CPM with a active exercise program using sling. CG was performed CPM 5 days a week, CSG performed CPM 2 days a week and a active exercise program using sling 3 days a week, and each intervention was performed for 40 minutes a day for a total of 4 weeks. Pain was evaluated using VAS (Visual analog scale), and balance was measured using BT4 (Balance training 4) to measure C90 area, trace length, and Sway average velocity with eyes open and closed. As a result, there was a significant decrease in pain in both groups, and there was also a significant difference in the amount of change between groups. In balance, all variables except C90 of CG showed significant changes after intervention, and there was a significant difference between C90 and Vel with eyes closed in the amount of change between groups. Therefore, we believe that CPM and active exercise program using sling are effective interventions to reduce pain and improve balance in total knee replacement patients.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1155-1162
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• 2014

Background: Despite mixed survival data, the utilization of contralateral prophylactic mastectomy (CPM) for the prevention of a contralateral breast cancer (CBC) has increased significantly over the last 15 years, especially among women less than 40. We set out to look at our own experience with CPM, focusing on outcomes in women less than 40, the sub-population with the highest cumulative lifetime risk of developing CBC. With an extended follow-up, we hoped to demonstrate differences in the long-term disease free survival (DFS) and overall survival (OS) among groups who underwent the procedure (CPM) versus those that did not (NCPM). Materials and Methods: We performed a retrospective review of all breast cancer patients less than age 40 diagnosed at Mount Sinai Medical Center between January 1, 1980 and December 31, 2010 (n=481). Among these patients, 42 were identified as having undergone CPM, while 195 were confirmed as being CPM-free during the observation period. A univariate and multivariate analyses were performed. Results: The CPM group had a significantly higher percentage of patients who were diagnosed between 2000 and 2010 (95.2% vs 40%, p=0.0001). The CPM group had significantly smaller tumors (0-2cm.: 41.7% vs 24.8%, p=0.04). Among the entire group of patients, the overall five- and 10-year DFS were 81.3% and 73.3%, respectively. CPM was significantly associated [HR 2.35 (1.02, 5.41); p=0.046] with 10-year OS, although a similar effect was not observed for five-year OS. Conclusions: We found that CPM has increased dramatically over the last 15 years, especially among white women with locally advanced disease. In patients less than 40, who are thought to be at greatest cumulative risk of secondary breast cancer, CPM provided an OS advantage, regardless of genetics, tumor or patient characteristics, and which was only seen after 10 years of follow-up.

• Archives of Pharmacal Research
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• v.28 no.7
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• pp.816-822
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• 2005

Catharsius protease-2 (CPM-2) was isolated from the body of dung beetles, Catharsius molossus, using a three step purification process (ammonium sulfate fractionation, gel filtration on Bio-Gel P-60, and affinity chromatography on DEAE Affi-Gel blue). The purified CPM-2, having a molecular weight of 24 kDa, was assessed homogeneously by SDS-polyacrylamide gel electrophoresis. The N-terminal amino acid sequence of CPM-2 was composed of X Val Gin Asp Phe Val Glu Glu lie Leu. CPM-2 was inactivated by $Cu^{2+}\;and\;Zn^{2+}$ and strongly inhibited by typical serine proteinase inhibitors such as TLCK, soybean trypsin inhibitor, aprotinin, benzamidine, and ${\alpha}_1$-antitrypsin. However, EDTA, EGTA, cysteine, $\beta$-mercaptoethanol, E64, and elastatinal had little effect on enzyme activity. In addition, antiplasmin and antithrombin III were not sensitive to CPM-2. Based on the results of a fibrinolytic activity test, CPM-2 readily cleaved $A{\alpha}-$ and $B{\beta}$-chains of fibrinogen and fibrin, and y-chain of fibrinogen more slowly. The nonspecific action of the enzyme resulted in extensive hydrolysis, releasing a variety of fibrinopeptides of fibrinogen and fibrin. Polyclonal antibodies of CPM-2 were reactive to the native form of antigen. The ELISA was applied to detect quantities, in nanograms, of the antigen in CPM-2 protein.

• Korean Journal of Construction Engineering and Management
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• v.5 no.5 s.21
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• pp.135-142
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• 2004

This paper proposes the CPM bar chart (CBC), a hybrid of the bar chart and the critical pad method (CPM). The CBC overcomes shortages of the fenced bar chart, while still keeping advantages. The fence with direction is applied instead of the broken fence, which triggers considerable problems to identify and apply in the fenced bar chart. In addition, the notorious task to find dummy activities is no longer required. Upon the benefits of simplicity in the bar chart and logical work sequence in the CPM network. the CBC provides a relatively easy way to create and understand a schedule, thus improving communication quality between project participants. With the advantages, the CBC can also be effectively applied to various scheduling techniques such as resource constrained scheduling, resource leveling, scheduling with activity split, delay impact analysis, etc.

• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.2
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• pp.128-132
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• 2010

Purpose: Nuclear medicine general operation room is radioactive control room which is used for the handling of radioisotope(R.I). Radioactive contamination materials must be under control and separated from general trash. With this experiments, we want to actively suggest the guideline of controling and operating radioactive contamination materials by measuring contamination degree and analyzing the causes which is not realized so far. Materials and Methods: Materials are selected from Oct. 2009 to March. 2010. salines which are used for labelling radiophamaceuticals and generator cap, saline needle cap, $^{99m}Tc$-needle cap saline vial which is generated from $^{99}Mo$/$^{99m}Tc$ generator. After measuring each surface contamination degree by survey meter, mean value and standard deviation one were solved out. Results: In result, After measuring surface contamination degree, radioactivity of saline for labelling radiophamaceuticals showed $14429{\pm}26378$ cpm (p<0.05) and in measured generators, foreign imported things showed that generator cap : $9{\pm}21$ cpm, saline vial : $17{\pm}28$ cpm. saline needle cap : $35{\pm}66$ cpm, $^{99m}Tc$-needle cap : $9{\pm}21$ cpm, saline vial $13{\pm}28$ cpm. domestic things showed that generator cap : $22852{\pm}52545$ cpm, saline needle cap : $87367{\pm}109711$ cpm, $^{99m}Tc$-needle cap : $9008{\pm}10459$ cpm, saline vial : $186416{\pm}158196$ cpm (p<0.05). Conclusion: The saline which is used for labelling, exceeded 1/10 of maximum permissible range. this is generated from radiophamaceuticals dilution procedure. and In generators, radioactive value of foreign import things showed closely background value. but which of domestic thing showed that exceeded more than 1000 values 1/10 of maximum permissible range. the causes of that is domestic generator is contaminated in manufacturing procedure. So, to dispose radioactive contamination materials which is could betaken out of, the control and operation must be radical under controlled by radioactive measuring, recording and equipping of its own. if this is kept well, we can prevent surely that radioactive waste could be disposed like as general trash.

• The Journal of Korean Academy of Prosthodontics
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• v.52 no.3
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• pp.186-194
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• 2014

Purpose: Process management is the activity which manages all procedure of construction by representing visually interrelation of operation or sequence setting. The purpose of this study was for reducing treatment period and higher efficiency of treatment through application of PERT/CPM (Program Evaluation & Review Technique/Critical Path Method) in dental clinic. Materials and methods: The patients were selected for study who needed more than 2 departments' cooperation for prosthodontic treatment in Wonkwang Dental University Hospital. Control group is composed of the patient's whole treatment plan, treatment period, numbers of hospital visit, treatment costs, treatment results. On the other hand, experiment group contains the patient's virtual treatment data based on PERT/CPM technique. We applied PERT/CPM in operation analysis. Results: Treatment period, numbers of hospital visit was decreased as 18.1% and 15.3% when we applied operation analysis based on charts. Also treatment cost in experiment group was 0.9% economized compared with control group's treatment cost. Conclusion: Application of PERT/CPM in dental clinic can achieve reliable treatment and reduced treatment period and establish plan of minimum treatment cost.

• Cement
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• s.37
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• pp.4-11
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• 1970

최근 급속히 팽창된 산업 구조와 이에 따른 업무량의 증가는 종래의 관리기술로서는 이를 성공적으로 처리할 수 없게 되었으며 아울러 인간의 미래조작능력의 증대와 기업구상력의 개발, 사회변동에 대비한 예측적인 계획의 수립 등 관리기능의 신장은 새로운 관리기법을 요구하게 되었으므로 PERT/CPM 수법이 신관리기법의 하나로 등장하게 되었다. PERT/CPM 이란 Program Evaluation Review and Technique, Critical Path Method 의 약자로서 우리말로는 계획수립 집행 및 평가로 번역되는데 이의 직역은 종속 및 총합 $\ulcorner$시스템$\lrcorner$ 과업의 동시진행 및 집중관리라 할 수 있는 것으로 시간과 비용을 절감하려는 기법인 것이다. 또한 PERT 기법은 복잡한 작업형태를 상호관련성있는 Network로 구성하고 제종속작업을 하나의 통일된 목표로 진행시키는 것을 의미한다. 이와 같은 PERT/CPM 기법은 제한된 자원의 효율적인 투자 및 관리와 불필요한 시간과 비용을 제거하여 준다. 현재 정부(경제기획원)는 PERT/CPM 제도를 도입하여 건설공사에 대한 예산관리제도를 설정중에 있으며 민간 및 정부투자기관으로서 현대건설주식회사와 한국전력주식회사와 이미 PERT/CPM 제도화방책을 연구기관에 위촉하여 제2단계적용을 시도하고 있는 것은 시대적 당위성에 따른 타당한 전망이라 하겠다. 거금 한국양회공업협회가 본제도의 도입 적용을 추진하기 위한 일련의 조사활동을 시작한 것은 시멘트 공업계의 새로운 경영관리체제를 모색하고 업계를 선도하는 중요한 전환점이 되리라 믿는다.

• The Journal of Internal Korean Medicine
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• v.30 no.3
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• pp.639-647
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• 2009

Objective : This study was case report to show the good effects of herbal medicine (Daekumeum-ja) and acupuncture complex therapy for central pontine myelinolysis (CPM). Method : A 44-year-old man suffering from CPM was chronic alcoholic without electrolyte disturbance. He showed symptoms of dysarthria, dysphagia, dizziness, weakness of lower extremities and gait disturbance. CPM was diagnosed at his former hospital by MR imaging. He had no positive response to western treatments. We treated the patient with herbal extract (Daekumeum-ja) and acupuncture. Results : After our treatments, there was no change of Brain CT. But overall symptoms of CPM were improved. Conclusion : This study suggests that herbal medicine (Daekumeum-ja) and acupuncture complex therapy is probably effective in the treatment of CPM.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.16 no.11
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• pp.1095-1102
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• 1991

In this paper, we proposed the differential demodulation technique of 2-h CPM and analyzed its error performances. We derived the sets of modulation indices of 2-h phase codes adequate to the differential detection. The power spectra of 2-h CPM signals with various sets of mudulation indices are illustrated and compared, Besides, the error performances for the differential detectors are calculated and detectors using Viterbi algorithm are compared and analyzed by computer simulations.