• Title/Summary/Keyword: COVID-19 endemic

Search Result 19, Processing Time 0.024 seconds

Modeling Incorporating the Severity-Reducing Long-term Immunity: Higher Viral Transmission Paradoxically Reduces Severe COVID-19 During Endemic Transition

  • Hyukpyo Hong;Ji Yun Noh;Hyojung Lee;Sunhwa Choi;Boseung Choi;Jae Kyoung Kim;Eui-Cheol Shin
    • IMMUNE NETWORK
    • /
    • v.22 no.3
    • /
    • pp.23.1-23.12
    • /
    • 2022
  • Natural infection with severe acute respiratory syndrome-coronavirus-2 or vaccination induces virus-specific immunity protecting hosts from infection and severe disease. While the infection-preventing immunity gradually declines, the severity-reducing immunity is relatively well preserved. Here, based on the different longevity of these distinct immunities, we develop a mathematical model to estimate courses of endemic transition of coronavirus disease 2019 (COVID-19). Our analysis demonstrates that high viral transmission unexpectedly reduces the rates of progression to severe COVID-19 during the course of endemic transition despite increased numbers of infection cases. Our study also shows that high viral transmission amongst populations with high vaccination coverages paradoxically accelerates the endemic transition of COVID-19 with reduced numbers of severe cases. These results provide critical insights for driving public health policies in the era of 'living with COVID-19.'

A Study on the Consumers' Intention to Visit Restaurants in COVID-19 Endemic (COVID-19 엔데믹 상황에서 소비자들의 레스토랑 방문의도에 관한 연구)

  • Hyun Ju Yun;Jee Hye Lee
    • Journal of the Korean Dietetic Association
    • /
    • v.30 no.1
    • /
    • pp.29-40
    • /
    • 2024
  • Coronavirus disease-2019 (COVID-19) has led to a decline in restaurant visits, which in turn has changed the decision-making process of consumers. This study aimed to investigate the factors influencing visit intention during the COVID-19 endemic by employing the expanded theory of planned behavior. A total of 291 samples were collected through an online survey for the analysis. Confirmatory factor analysis, correlation analysis, and structural equation path analysis were performed on the collected data using the Analysis of Moment Structures (AMOS) statistical program. The findings of the study revealed the positive effects of attitude and perceived behavioral control and the negative effects of subjective norms on desire. Second, desire played a mediating role between antecedent variables (attitude, subjective norm, perceived behavioral control) and the visit intention. These findings are meaningful in that they expand the theory of planned behavior during the COVID-19 endemic based on factors that affect visit intention.

Pre-existing Immunity to Endemic Human Coronaviruses Does Not Affect the Immune Response to SARS-CoV-2 Spike in a Murine Vaccination Model

  • Ahn Young Jeong;Pureum Lee;Moo-Seung Lee;Doo-Jin Kim
    • IMMUNE NETWORK
    • /
    • v.23 no.2
    • /
    • pp.19.1-19.10
    • /
    • 2023
  • Endemic human coronaviruses (HCoVs) have been evidenced to be cross-reactive to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although a correlation exists between the immunological memory to HCoVs and coronavirus disease 2019 (COVID-19) severity, there is little experimental evidence for the effects of HCoV memory on the efficacy of COVID-19 vaccines. Here, we investigated the Ag-specific immune response to COVID-19 vaccines in the presence or absence of immunological memory against HCoV spike Ags in a mouse model. Pre-existing immunity against HCoV did not affect the COVID-19 vaccine-mediated humoral response with regard to Ag-specific total IgG and neutralizing Ab levels. The specific T cell response to the COVID-19 vaccine Ag was also unaltered, regardless of pre-exposure to HCoV spike Ags. Taken together, our data suggest that COVID-19 vaccines elicit comparable immunity regardless of immunological memory to spike of endemic HCoVs in a mouse model.

The Effects of Personal Emotion and Social Change Perception caused by COVID-19 on Disaster Response Perception after the Post-Endemic (코로나19로 인한 개인정서와 사회변화 인식이 엔데믹 이후 재난대처 인식에 미치는 영향에 대한 연구)

  • Lee, Wan-Taek;Lim, Seong-Hyeon;Jo, Changik;Lee, Jongseok;Jung, Deuk
    • Journal of Industrial Convergence
    • /
    • v.20 no.8
    • /
    • pp.127-136
    • /
    • 2022
  • This study was conducted using a multiple regression model to empirically analyze the impact of personal emotions and social change perceptions of pandemic experienced by Korean people in the COVID-19 situation on the perception of disaster response after the endemic. For this end, we used the survey data with 996 respondents on 「Daily Changes of the People After COVID-19」conducted by the Korea Press Promotion Foundation. The results showed that COVID-19 positive emotions and social change perception factors had a positive (+) effect on disaster response perception, while the sense of community had a moderating effect that alleviated COVID-19 negative emotions which had a negative (-) effect. The most influential factors on disaster response perception after the endemic were COVID-19 positive emotions and community sense that had pride and stability in Korean society during disaster situations. Therefore, this study suggests that systematic disaster response manuals and control towers that give the public pride and stability are more strongly requested for the government's prior and follow-up measures performed in the post-endemic disaster situation, and that the people are asked to have the community sense to overcome disasters together rather than to respond with personal actions and judgments.

The Effect of Long Coronavirus Disease on Obesity and the Role of Korean Medicine (롱코비드가 비만에 미치는 영향과 그에 대한 한의학의 역할)

  • Han, Kyungsun;Kim, Myung-Ho
    • Journal of Korean Medicine for Obesity Research
    • /
    • v.22 no.1
    • /
    • pp.77-85
    • /
    • 2022
  • While the Coronavirus disease 2019 (COVID-19) pandemic is gradually turning into an endemic disease, concerns about post COVID-19 conditions (Long COVID) are emerging. Obesity is a major risk factor for severe complications of COVID-19, and COVID-19 has a wide range of effects on obesity and metabolic function. This paper aims to examine the interaction between COVID-19 and obesity, the effects and mechanisms of long COVID on obesity, and the role of Korean medicine on long COVID-related obesity. Obesity may worsen with cardiometabolic damage and psychosocial insecurity during COVID-19 and long COVID-induced neuroinflammation, systemic inflammation, mitochondrial dysfunction, and hypoxia also may aggravate obesity. Korean Medicine treatments, which have been widely used to treat obesity, have the potential to improve obesity in the era of long COVID by intervening in these mechanisms.

COVID-19 and Plasmodium ovale Malaria: A Rare Case of Co-Infection

  • Caglar, Bilge;Karaali, Ridvan;Balkan, Ilker Inanc;Mete, Bilgul;Aygun, Gokhan
    • Parasites, Hosts and Diseases
    • /
    • v.59 no.4
    • /
    • pp.399-402
    • /
    • 2021
  • The COVID-19 pandemic continues to be a major health problem worldwide. Timely diagnosis of co-infections mimicking COVID-19, such as malaria, might be challenging particularly in non-endemic areas. We report the first case of COVID-19 and Plasmodium ovale malaria co-infection from our region aiming to highligt the importance of travel history and prophylaxis in malaria management in the context of pandemic. The galloping sound can sometimes be a harbinger of zebra besides the horse.

Shifting Meme Content during Information Development on the COVID-19 Pandemic in Indonesia

  • Kadri, Kadri;Jumrah, Jumrah
    • Journal of Information Science Theory and Practice
    • /
    • v.10 no.1
    • /
    • pp.30-44
    • /
    • 2022
  • This research aims to identify and reveal the meaning of memes about COVID-19, and explain changes in meme content in regard to the information development of COVID-19 in Indonesia published by the mass media and online media. The data is sourced from memes that are shared on social media, especially WhatsApp groups in the period of January to June 2020. To reveal the meaning of memes, a semiotic analysis of Roland Barthes' model is used. Qualitative analysis is used to reveal the relationship between memes and the information development of COVID-19 in Indonesia. The results of the study show that meme content has shifted according to three stages of information development of COVID-19 in Indonesia published by the mass media and online media. When COVID-19 was not yet confirmed in Indonesia, meme content contained mostly humor that was not educative, moreover it seemed to underestimate the coronavirus. Meme content which is mostly humorous and pornographic occurred when COVID-19 was confirmed in Indonesia and during the lockdown policy. At last, as the government has begun to distribute social assistance, the meme content looks more critical. The results of this research emphasize the urgency of the mass media as a source of public information during the COVID-19 pandemic, become a reference for the community in making memes as a forum for expressing feelings and social criticism, and serve as a reference for the government to act and make the right decisions related to the pandemic that is endemic in their country.

Plastic recycling in South Korea: problems, challenges, and policy recommendations in the endemic era

  • Uhram Song;Hun Park
    • Journal of Ecology and Environment
    • /
    • v.48 no.1
    • /
    • pp.74-84
    • /
    • 2024
  • Background: Despite many environmental problems, plastic waste emissions have been a significant surge during last few decades in the Republic of Korea. Furthermore, the emergence of the coronavirus disease 2019 (COVID-19) pandemic has lead to an increased use and disposal of plastic waste worldwide. This paper tried to present summarized data related to the production and disposal of plastics especially before and after the COVID-19 pandemic with environmental impacts of plastics. Also, review of plastic waste reduction policies and feasible policies to promote an act for a safe, sustainable environment are presented. Results: Plastics cause many environmental problems due to their non-degrading properties and have a huge direct and indirect impact on Ecosystems and Public Health. Microplastics need a lot of attention because their environmental effects are not yet fully identified. Despite plastic's significant impact on climate change, the impact is not yet widely known to the public. Since the COVID-19 pandemic, the use of plastic has surged and recycling has decreased due to the increase in delivery food and online shopping. Korea is introducing very active plastic and waste management policies, but it is necessary to implement more active policies by referring to the cases of other countries. Conclusions: In this article, we have scrutinized the evolution of plastic waste generation in the aftermath of the COVID-19 pandemic and delved into policy frameworks adopted by other nations, which South Korea can draw valuable lessons from. The formidable challenges posed by plastic waste, the remarkable shifts witnessed during the COVID-19 era, and the multifaceted response strategies elucidated in this paper all play a pivotal role in steering South Korea toward a sustainable future.