• Korean Journal of Veterinary Research
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• v.57 no.3
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• pp.197-200
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• 2017

This study evaluated the effect of a combination of acetaminophen and vitamin C (CAV) on reducing serum cortisol and tumor necrosis $factor-{\alpha}$ ($TNF-{\alpha}$) concentrations in piglets vaccinated with foot-and-mouth disease (FMD) vaccine. Piglets were vaccinated with FMD vaccine and treated with CAV at concentrations of 0.0, 0.5, 1.0, and 2.0 kg/ton feed (P-CON, AD-1, AD-2, and AD-3, groups, respectively) for 5 days post-vaccination. Cortisol and $TNF-{\alpha}$ levels at 5 days post-treatment in the AD-1-3 groups were significantly lower than that in the P-CON group (p < 0.05). There were no significant differences between AD-2 and AD-3 groups and non-vaccinated, non-CAV-treated piglets.

• Child Health Nursing Research
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• v.14 no.2
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• pp.138-145
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• 2008

Purpose: This study, using a pre-posttest design of non-equivalence comparative groups, was done to determine effects of KC (kangaroo care) on weight and SH (stress hormone) of premature infants. Method: Participants were 31 premature infants assigned to KC(14) or CG(control group)(17). Data were collected from June 2006 to February 2007. KC was given for 60 minutes at a time, Mon, Wed, and Fri for a 10 times. Body weight was measured at a fixed time daily and serum cortisol was examined as part of routine blood testing, frequent for premature infants. Results: The weight for infants in the KC group was higher than the control. The difference was significant between both the two groups, and the 2 measurement times(F=12.7, p=.001). SH(cortisol) in infants of KC group decreased than CG, but there was no valid difference from the statistical viewpoint. Conclusion: The result of the study suggest that KC contributes to weight increase in premature infants and also that KC is effective for SH reduction in spite of the lack of statistical validity. Therefore, our conclusion is that KC can be used as an independent nursing intervention for development and advance of premature infants.

• Korean Journal of Occupational Health Nursing
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• v.9 no.2
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• pp.79-85
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• 2000

All clinical nurses are not only faced with the physical and emotional needs of patients but also exposed to the heavy workload. In clinical settings, the nurses' stress becomes more and more critical. Understanding the stress experienced by nurses is essential for planning programs to enhance patient care and to promote nurses health. Many methods to reduce the stress were practiced for patients. In this study, the investigator examined how the imagery influence the reducing the stress of clinical nurses. For this study, the recorded tape for imagery developed in the Society of Rheumatics was applied. In order to evaluate the effect of imagery on the stress of clinical nurse, stress score, serum cortisol, blood pressure, and pulse were measured on 20 clinical nurses for 20 days. The results were as follows: 1. Stress score decreased significantly in the experimental group. And the rate of decrease in stress score was significantly higher in experimental group than in the control group. 2. The level of serum cortisol decreased significantly after the application of imagery. 3. Systolic blood pressure decreased significantly after the application of imagery. These results indicate that after applying the method of imagery on the nurses, stress score, serum cortisol level, and systolic blood pressure were significantly decreased. Therefore, this study proves that imagery is one of the methods to reduce the stress of clinical nurses.

• The Journal of Korean Academic Society of Nursing Education
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• v.13 no.2
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• pp.212-219
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• 2007

Purpose: The purpose of this study was to examine the effects of hand stimulation intervention by moxa on fatigue and the blood cortisol level in pregnant women. Method: This study was conducted using a nonequivalent control-group pretest-posttest design from Oct 13 to Dec 15, 2005. The participants were pregnant women in the Gyeong-gi area. The numbers of experimental and control subjects were 16 and 13, respectively. The hand stimulation intervention by moxa was applied to the experimental group three times a week, for a total of fifteen times for five weeks. Result: The blood cortisol level was statistically significantly different between the two groups. However, the degree of fatigue was statistically insignificant. Conclusion: These results suggest that hand stimulation intervention by moxa can be used as an effective nursing intervention in pregnant women. The implications for nursing practice and directions for future research are discussed.

• The Journal of Internal Korean Medicine
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• v.13 no.1
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• pp.143-155
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• 1992

The following results were obtained from the observation on the change of plasma cortisol concentration in the experiment of intravenous administration of Haengsoyeum Water Extract in the rabbit. And the effects of Haengsoyeum extract on the contractile force of the isolated guinea pig trachea smooth muscle. 1. In intravenous administration the plasma cortisol concentration increased significantly about 1 hours after with a does of 0.2 ml/kg. 2. In intravenous administration the plasma cortisol concentration increased significantly about from 1 to 3 hours after with a does of 0.4 ml/kg. 3. The contractile response of the trachea smooth muscle of isolated guinea pig to histamine $10^{-4}\;M$ was significantly inhibited by Haengsoyeum extract. 4. The contractile response of the trachea smooth muscle of isolated guinea pig to acetylcholine $10^{-4}\;M$ was considerably inhibited by Haengsoyeum extract. 5. The contractile response of the trachea smooth muscle of isolated guinea pig to 5-hydroxytryptamine $10^{-4}\;M$ was inhibited by Haengsoyeum extract.

• Journal of Korean Biological Nursing Science
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• v.10 no.2
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• pp.184-193
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• 2008

Purpose: Anxiety and depression are the concepts that commonly used as an emotional approach in the nursing researches and most of researches have been used questionnaires as a marker of anxiety and depression. There were few researches using physiological markers in measuring anxiety and depression. Methods: Journals published between 1950 and 2007 that include depression and anxiety measuring through physiological markers were reviewed. Results: As in the case of the hypothlamus-pituitary-adrenal axis system, it appeared that cortisol, epinephrine, and norepinephrine belonged to the category of hormones which were responsive to anxiety and depression. Plasma norepinephrine was a marker of the anxiety whereas plasma cortisol was a marker of the depression. The anxiety and depression were correlated with immune and taste, but it considered as an outcome variable not a physiological marker. Conclusion: Catecholamine and cortisol reflect anxiety and depression state. Our findings suggest that further researches are needed to distinguish between markers and outcomes of depression and anxiety using physiological markers.

• Korean Journal of Adult Nursing
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• v.20 no.5
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• pp.697-706
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• 2008

Purpose: The purpose of this study was to identify the effects of the phytoncides on serum cortisol level, vital signs and life stress of college students. Methods: This study was nonequivalent control group non-synchronized design. The subjects consisted of 60(control group: 28, experimental group: 32). The phytoncides mixed the pine(pinus sylvestris) oil with the cypress(cupressus sempervirens) oil in the same rate. In the experiment, it was put in an aroma-necklace bottle and inhaled 3 times per day(9AM, at noon, before going to bed) for 2 weeks. The data were analyzed by the SPSS version 12.0 program. Results: In the experimental group systolic BP(F=15.603, p=.000), diastolic BP(F=29.489, p=.000) and serum cortisol level(F=4.968, p=.000) were significantly decreased. Conclusion: The phytoncides inhalation is a partly help to reduce college students' life stress. The phytoncides is the incense of the familial tree. We recommended to examine what differences between the green shower and the phytoncides inhalation for the stress reduction.

• Journal of Korean Academy of Nursing
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• v.34 no.5
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• pp.829-837
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• 2004

Purpose: The purpose of this study was to determine the effects of a 6-week Tai Chi exercise program on reducing blood pressure for hypertensive patients. Method: A non-equivalent pretest-posttest experimental design was used. Participants were recruited from the Community Health Center in Busan, Korea. Twenty-eight hypertensive patients participated in this study. Among them, fourteen were in the experimental group and the rest are in the control group. Members in the experimental group participated in a 6- week program of Tai Chi exercise. In order to evaluate the effects of the Tai Chi program, blood pressure, total cholesterol, and cortisol level were measured before and after week 6. Result: After the 6-week Tai Chi program, there were significant differences in systolic pressure (t=-3.13, p=.004) and diastolic blood pressure (t=-4.75, p=.000) in the experimental group when compared to the control group. However there were no significant differences in the total cholesterol (t=1.07, p=.294) and cortisol level (F=1.35, p=.256). Conclusion: These results suggest that a 6-week Tai Chi program can be utilized as an effective nursing program to reduce blood pressure for hypertensive patients.

• Asian Oncology Nursing
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• v.11 no.2
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• pp.93-100
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• 2011

The purpose of this study was to examine the effects of laughter therapy on mood, state anxiety, and serum cortisol based on a Stress-Coping Model for preoperative breast cancer patients. Methods: The study used a nonequivalent control group pretest-posttest design. The participants were 40 breast cancer patients who were admitted to one general hospital for surgery in 2009 (experimental group 23, control group 17). The experimental group received one hour laughter therapy consisting of dance, lots of laughter techniques, and meditation. Results: The mean ages were 47 years (experimental group) and 49 years (control group). There were no significant differences in demographic and disease-related characteristics between the two groups. After the intervention, the scores of mood and state-anxiety of experimental group were significantly improved than those of control group. However, no difference was found in serum cortisol. Conclusion: The laughter therapy was partially effective in improving stress response in patients with breast cancer. Further research is needed to develop and evaluate the longer periods of interventions to testify the effects on serum cortisol, and other biochemical variables.

• Women's Health Nursing
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• v.11 no.4
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• pp.265-272
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• 2005

Purpose: To investigate the effect of infant massage on stress, immune function and self-confidence in postpartum mothers. Method: From September, 2003 to February, 2004, 65 women who had delivered babies and were enrolled in the postpartum clinic were assigned to the experimental group or control group. In the experimental group, infant massage was given for 20 minute sessions twice a day from 4 days to 14 days after delivery. The instruments were Parental Stress Index, serum cortisol levels, WBCs, lymphocytes, and Self Confidence Scale. Results: Stress scores, WBCs and lymphocytes showed significant differences by the time, but there weren't significant differences according to the group and interactions between the group and the time. Cortisol and self-confidence scores showed significant differences by the time and the group. Conclusions: Applying massage to their newborn baby influenced cortisol levels of postpartum mothers. Therefore stress, cortisol, and immune functions in postpartum mothers should be generally screened and follow up studies are needed for the effective application of massage in postpartum mothers.