• Title/Summary/Keyword: CONTAIN

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Identification of SUMOylated proteins in neuroblastoma cells after treatment with hydrogen peroxide or ascorbate

  • Grant, Melissa M.
    • BMB Reports
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    • v.43 no.11
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    • pp.720-725
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    • 2010
  • The small ubiquitin-like modifier (SUMO) proteins have been implicated in the pathology of a number of diseases, including neurodegenerative diseases. The conjugation machinery for SUMOylation consists of a number of proteins which are redox sensitive. Here, under oxidative stress ($100{\mu}M$ hydrogen peroxide), antioxidant ($100{\mu}M$ ascorbate) or control conditions 169 proteins were identified by electospray ionisation fourier transform ion cyclotron resonance mass spectrometry. The majority of these proteins (70%) were found to contain SUMOylation consensus sequences. From the remaining proteins a small number (12%) were found to contain possible SUMO interacting motifs. The proteins identified included DNA and RNA binding proteins, structural proteins and proteasomal proteins. Several of the proteins identified under oxidative stress conditions had previously been identified as SUMOylated proteins, thus validating the method presented.

Sustainable Use of Marine Microorganisms

  • Lee Yoo Kyung;Lee Jung Hyun;Kwon Kae Kyoung;Lee Hong Kum
    • Proceedings of the Microbiological Society of Korea Conference
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    • 2002.10a
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    • pp.94-99
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    • 2002
  • The oceans cover about $71\%$ of the Earth's crust and contain nearly 300,000 described species. Free-living bacteria in the sea and symbiotic bacteria of marine invertebrates are proving to be valuable sources of useful bioactive compounds. Marine sponges, in particular, which contain diverse communities of bacteria, produce many classes of compounds that are unique to the marine environment. Uncultured microorganisms are commonly believed to represent $99.9\%$ of the whole microbial community. They have been investigated for the possibility of isolating and over-expressing genes in viable microorganisms. Strict symbiotic species that have been adapted to the host are candidate unculturable species. With the enormous potential for discovery, development, and market value of marine derived compounds, supply of the products is a major limiting factor for further development.

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End-Uses Studies on the Physical Chemical Properties of Socks in the Market (시판 양말의 물성에 관한 소비과학적 검사)

  • 조현혹
    • Journal of the Korean Home Economics Association
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    • v.19 no.2
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    • pp.143-149
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    • 1981
  • Consumer consider the purpose for which they plan to use clothes when they purchase it, and the socks in textile products is evaluated in the same way. serviceability is judged by the extent to which the socks will be useful for its intended purpose. It should retain its original shape and size, good air permeability, good absorbency, good abrasion resistance, high fastness etc. Owing to importance of serviceability in socks, in this paper, these end-use requirement characteristics were tested. The results obtained were as follows: 1. Blend ratios were different between the indicated fiber contents on labels and the testing ones. 2. Air permeability was higher in the samples which contain less stitch density, and hydroscopicity was higher in those which contain natural fibers such as cotton and wool. 3. Shrinkage depended on the blend ratios of cotton and wool, and elastic recovery was better in the course direction than in the wale direction. 4. Pilling was conspicuous in the synthetic fibers such as polyester and nylon, and fastness of laundering and perspiration was higher in the fading grade than in the staining grade.

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The Identification Of Multiple Outliers

  • Park, Jin-Pyo
    • Journal of the Korean Data and Information Science Society
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    • v.11 no.2
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    • pp.201-215
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    • 2000
  • The classical method for regression analysis is the least squares method. However, if the data contain significant outliers, the least squares estimator can be broken down by outliers. To remedy this problem, the robust methods are important complement to the least squares method. Robust methods down weighs or completely ignore the outliers. This is not always best because the outliers can contain some very important information about the population. If they can be detected, the outliers can be further inspected and appropriate action can be taken based on the results. In this paper, I propose a sequential outlier test to identify outliers. It is based on the nonrobust estimate and the robust estimate of scatter of a robust regression residuals and is applied in forward procedure, removing the most extreme data at each step, until the test fails to detect outliers. Unlike other forward procedures, the present one is unaffected by swamping or masking effects because the statistics is based on the robust regression residuals. I show the asymptotic distribution of the test statistics and apply the test to several real data and simulated data for the test to be shown to perform fairly well.

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Effect of Spray System on Fission Product Distribution in Containment During a Severe Accident in a Two-Loop Pressurized Water Reactor

  • Dehjourian, Mehdi;Rahgoshay, Mohammad;Sayareh, Reza;Jahanfarnia, Gholamreza;Shirani, Amir Saied
    • Nuclear Engineering and Technology
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    • v.48 no.4
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    • pp.975-981
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    • 2016
  • The containment response during the first 24 hours of a low-pressure severe accident scenario in a nuclear power plant with a two-loop Westinghouse-type pressurized water reactor was simulated with the CONTAIN 2.0 computer code. The accident considered in this study is a large-break loss-of-coolant accident, which is not successfully mitigated by the action of safety systems. The analysis includes pressure and temperature responses, as well as investigation into the influence of spray on the retention of fission products and the prevention of hydrogen combustion in the containment.

Ultrastructural Study of Tentacular Pigment Cells in the Chinese Mystery Snail, Cipangopazudina chinensis mazleata Reeve (논우렁이(Cipangopaludina chinensis malleuta Reeve) 촉수 색소세후의 징세횡조에 관한 연구)

  • 송용직;문영진김우갑김창환
    • The Korean Journal of Zoology
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    • v.30 no.3
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    • pp.292-300
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    • 1987
  • The ultrastructure of the tentacular pigment cells and the origin of the pigment granules in the Chinese mystery snail, Cipangopaludina chinensis malleata Reeve, are studied with electron microscope. Tentacular pigment cells of the Enail are the melanophores which contain electron dense melanosomes(melanin pigment granules) . Melanophores are distributed among the connective tissues but otter kind of dermal chromatephores are not observed. The epidermal melanin units are observed in the epithelial tissues of the tentacles. Among the several kinds of epithelial cells, only the epithelial supporting cells contain these pigment granules. Synthesis of the pigment materials is from the rough ER and pigment granules are finally being packaged and released by the Golgi complexes but limiting membrane of these granules are presumed to be originated from the smooth ER.

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Detection of DNA Rearrangement in Rice Using a Cosmid Library

  • Mun, Eun-Pyo;Nahm, Baek-Hie
    • Animal cells and systems
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    • v.1 no.4
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    • pp.629-635
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    • 1997
  • Previously we reported the migration and rearrangement of a chloroplast gene cluster into mitochondria. The exact genomic locations of the clusters, modes of the gene rearrangement and mechanisms of the interorganellar migration of the clusters have yet to be understood. The detailed analysis needs to include a larger region of DNA surrounding each cluster. To study DNA rearrangement and migration in more detail a cosmid library was constructed using the total rice genomic DNA including nuclear, chloroplast and mitochondrial DNA. From this cosmid library, a sub-library was obtained by selecting the clones hybridized to various regions of chloroplast DNA. According to the hybridization pattern 136 clones from the sub-library were classified into 29 groups. Detailed analysis of these clones revealed that in addition to authentic chloroplast DNA, the clones contain its homologs resulted from rearrangement and mutation. We analyzed two clones in detail, which contain different rp12 homologs resulted from rearrangement and/or migration, respectively.

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A STUDY OF THE ROOT CANAL MORPHOLOGY OF HUMAN MAXILLARY FIRST MOLAR WITH TRANSPARENT SPECIMENS (투명표본(透明標本)에 의(依)한 하악제1대구치(下顎第1大口臼齒)의 근관형태(根管形態)에 관(關)한 연구(硏究))

  • Kim, Kye-Yong
    • Restorative Dentistry and Endodontics
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    • v.3 no.1
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    • pp.12-16
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    • 1977
  • One hundred human maxillary first molars were injected with china ink, decalcified, cleared, and used in vitro study to determine the number of root canals, the frequency and location of lateral canals, canals per root, and frequency of apical deltas. The results were as follows; 1. The mesiobuccal root was found to contain a single primary canal in 53% of the teeth studied and two canals in 47 % of the teeth studied. 2. In mesiobuccal roots with two canals, the seperated apical foramen appeared 32% of the specimens and the common apical foramen 15% of the specimens. 3. Of the 347 canals studied, 26.9% of the canals were found to contain lateral canals and these ramifications were mainly located in the apical third of the root.

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Code-Reuse Attack Detection Using Kullback-Leibler Divergence in IoT

  • Ho, Jun-Won
    • International journal of advanced smart convergence
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    • v.5 no.4
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    • pp.54-56
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    • 2016
  • Code-reuse attacks are very dangerous in various systems. This is because they do not inject malicious codes into target systems, but reuse the instruction sequences in executable files or libraries of target systems. Moreover, code-reuse attacks could be more harmful to IoT systems in the sense that it may not be easy to devise efficient and effective mechanism for code-reuse attack detection in resource-restricted IoT devices. In this paper, we propose a detection scheme with using Kullback-Leibler (KL) divergence to combat against code-reuse attacks in IoT. Specifically, we detect code-reuse attacks by calculating KL divergence between the probability distributions of the packets that generate from IoT devices and contain code region addresses in memory system and the probability distributions of the packets that come to IoT devices and contain code region addresses in memory system, checking if the computed KL divergence is abnormal.

Reduction of Edge Artifact in Adaptive Template Filtering (적응 템플릿 필터링에서의 Edge artifact 제거)

  • Ahn, C.B.;Song, Y.C.
    • Proceedings of the KIEE Conference
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    • 2000.07d
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    • pp.2921-2923
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    • 2000
  • Adaptive template filtering has been proposed recently for an enhancement of signal-to-noise ratio. In some magnetic resonance images whose gray levels have relatively small dynamic ranges, e.g., T1 imaging, however, artificial stair-like artifact is observed in edge regions. This is partially due to edge enhancement effect in such voxels that contain multiple compounds at the boundaries of tissues. The gray levels of these voxels tend to change those of near voxels that contain single compound by the adaptive filtering, which exaggerate edge discontinuities. In this paper, we propose a technique to eliminate such artifact by identifying those voxels and assigning a larger template for them. Filtered images with the proposed technique show substantial visual enhancement at the edges without degradation of peak signal-to-noise ratio compared to the original adaptive template filtering for both magnetic resonance images and phantom images

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