• Title/Summary/Keyword: COG

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Metabolic Pathways of 1309 Prokaryotic Species in Relation to COGs (COG pathways에서 원핵생물 1,309종의 대사경로)

  • Lee, Dong-Geun;Kim, Ju-Hui;Lee, Sang-Hyeon
    • Journal of Life Science
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    • v.32 no.3
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    • pp.249-255
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    • 2022
  • Metabolism is essential for survival and reproduction, and there is a metabolic pathways entry in the clusters of orthologous groups of proteins (COGs) database, updated in 2020. In this study, the metabolic pathways of 1309 prokaryotes were analyzed using COGs. There were 822 COGs associated with 63 metabolic pathways, and the mean for each taxon was between 200.50 (mollicutes) and 527.07 (cyanobacteria) COGs. The metabolic pathway composition ratio (MPCR) was defined as the number of COGs present in one genome in relation to the total number of COGs constituting each metabolic pathway, and the number of pathways with 100% MPCR ranged from 0 to 26 in each prokaryote. Among 1309 species, the 100% MPCR pathways included murein biosynthesis associated with cell wall synthesis (922 species); glycine cleavage (918); and ribosomal 30S subunit synthesis (903). The metabolic pathways with 0% MPCR were those involving photosystem I (1263 species); archaea/vacuolar-type ATP synthase (1028); and Na+-translocation NADH dehydrogenase (976). Depending on the prokaryote, three to 49 metabolic pathways could not be performed at all. The sequence of most highly conserved metabolic pathways was ribosome 30S subunit synthesis (96.1% of 1309 species); murein biosynthesis (86.8%); arginine biosynthesis (80.4%); serine biosynthesis (80.3%); and aminoacyl-tRNA synthesis (82.2%). Protein and cell wall synthesis have been shown to be important metabolic pathways in prokaryotes, and the results of this study of COGs related to such pathways can be utilized in, for example, the development of antibiotics and artificial cells.

An Experimental Study on Balancing Stabilization of a Service Robot by Using Sliding Mechanism (슬라이딩 메커니즘을 이용한 서비스 로봇의 밸런싱 자세의 안정화에 대한 실험연구)

  • Lee, Seungjun;Jung, Seul
    • Journal of Institute of Control, Robotics and Systems
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    • v.19 no.3
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    • pp.233-239
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    • 2013
  • This paper presents the analysis and control of the position of the COG (Center of Gravity) for a two-wheel balancing robot. The two-wheel balancing robot is required to maintain balance by driving two wheels only. Since the robot is not exactly symmetrical and its dynamics is changing with respect to moving parts, robust balancing control is difficult. Balancing performance becomes difficult when two arms hold a heavy object since the center of gravity is shifted out of the wheel axis. Novel design of a sliding waist mechanism allows the robot to react against the shift of the COG by moving the whole upper body to compensate for the imbalance of the mass as a counter balancer. To relocate the COG position accurately, the COG is analyzed by force data measured from two force sensors. Then the sliding COG mechanism is utilized to control the sliding waist position. Experimental studies are conducted to confirm the proposed design and method.

The Faulty Detection of COG Using Image Subtraction (이미지 정합을 이용한 COG 불량 검출)

  • Joo, Ki-See
    • Proceedings of KOSOMES biannual meeting
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    • 2005.11a
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    • pp.203-208
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    • 2005
  • The CGO (Chip on Glass) to be measured a few micro unit is captured by line scan camera for the accuracy of chip inspection. But it is very sensitive to scan speed and lighting conditions. In this paper, we propose the methods to increase the accuracy of faulty detection by image subtraction. Image subtraction is detected faultiness by subtracting the image of a ' perfect ' COG from trot of the sample under tests. For image subtraction to be successful, the two images must be pre챠sely registered The two images is registered by the area segmentation pattern matching, and the result image get by operating the gradient mask image and the image to practice subtraction. A series of experimentation showed that the proposed algorithm shows substantial improvement over the other image subtraction methods.

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The Kinematic Difference to the Skill Level in the Yurchenko Stretch Skill of Horse Vaulting (도마 유리첸코 동작 시 숙련도에 따른 운동학적 차이)

  • Yoon, Chang-Sun;Kim, Tae-Sam
    • Korean Journal of Applied Biomechanics
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    • v.16 no.2
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    • pp.135-144
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    • 2006
  • This study was to investigate the kinematic analysis to score of the Yurchenko stretch skill according to phases in a horse vaulting. For this study, 8 male national gymnasts were participated in acquiring three dimensional kinematical imagining data with four Sony PD-150 video cameras After digitizing motion, the Direct Linear Transformation(DLT) technique was employed to obtain 3-D position coordinates. The kinematic factors of the distance, velocity and angle variable were calculated for Kwon3D 3.1. The following conclusions were drawn; 1) The COG resultant velocity of the less skilled group decreased in PRF phase because the less skilled group had a larger flexion-knee angle than the skilled group in BC phase, Because the less skilled group had larger flexion-shoulder angle than the skilled group in HTO phase, At blocking movement, the body inclined a moving direction. By means of it, COG lowered 2) The skilled group had a more rapid COG's vertical velocity than the less skilled group at HTD and HTO event in HC phase, because this was performed the blocking movement with body angle and contacted on a horse vaulting small and its time short by means of contacting hands on a horse vaulting quickly. Such blocking movement made the vertical up-flight movement easy at POF phase bringing out rapid COG's vertical velocity after take off a horse vaulting.

Effects of Virtual Reality Horse Riding Simulator Training Using a Head-Mounted Display on Balance and Gait Functions in Children with Cerebral Palsy: A Preliminary Pilot Study

  • Kim, Hae Won;Nam, Ki Seok;Son, Sung Min
    • The Journal of Korean Physical Therapy
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    • v.31 no.5
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    • pp.273-278
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    • 2019
  • Purpose: The purpose of this study was to investigate the effects of three-dimensional virtual reality horse riding simulator training using a head-mounted display on gait and balance in children with cerebral palsy. Methods: Ten children with cerebral palsy were randomly assigned to the horse riding simulator (HRS) group (n=5) or the horse riding simulator with virtual reality (HRSVR) group (n=5). To evaluate balance, center of gravity (COG) sway velocity and total sway distance of each group were assessed using the Wii balance board, and gait speed and stride length of each group were assessed using a gait analysis system. Results: Intra-group comparisons between pre- and post-intervention measures revealed that there were significant changes in all gait and balance variables such as stride length, gait velocity, COG sway velocity and COG sway distance in the HRSVR group (p<0.05). In the HRS group, there were significant changes in all variables except stride length (p<0.05). In addition, inter-group comparisons showed significant differences between the two groups in stride length, gait velocity and COG sway distance except COG sway velocity (p<0.05). Conclusion: The findings of this study suggest that horse riding simulator training combined with 3D virtual reality can be a new positive therapeutic approach for improving functional performance in children with cerebral palsy.

Kinematic Analyses of Women's Pole Vault in IAAF World Championships, Daegu 2011 (2011 대구 세계육상선수권대회 여자 장대높이뛰기경기 기술의 운동학적 분석)

  • Choi, Kyoo-Jeong;Yi, Kyung-Ok;Kim, Nam-Hee;Kang, Ji-Eun;Kim, Hye-Lim
    • Korean Journal of Applied Biomechanics
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    • v.21 no.5
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    • pp.561-571
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    • 2011
  • The purpose of this study was to perform the kinematic analyses of the women's pole vault skills in IAAF World Championships Daegu 2011. Subjects were the 1st through 8th place finishers in the pole vault. The kinematic analyses were divided into four phases: two dimensional run up analysis, and three dimensional analyses for the remaining plant, swing up, and extension phases. Run-up variables consisted of run up distance, number of steps, average step length, ratio of step length to height, average velocity at the final 5~10 m, approach position. Three variables were analyzed during plant: pole angle, center of gravity (COG) velocity, and COG takeoff angle. Swing up phase variables included: pole flection angle, COG velocity (horizontal, vertical, resultant), COG trajectory and bar approach angle of COG. Compared to the 2009 World Championships in Berlin, the average vault height increased, while run up velocity and approach position were almost unchanged. However, horizontal velocity during the last two steps of the final approach decreased noticeably compared to speeds from 1990. These results reflect the change in both technique and physical fitness in pole vaulters. During extension, the peak height of COG surpassed the clearance height by an average of 0.11m. These specific results can help coaches and athletes modify training and improve performance.

Comparison of Mitochondria-related Conserved Genes in Eukaryotes and Prokaryotes (진핵생물과 원핵생물의 미토콘드리아 관련 보존적 유전자 비교)

  • Lee, Dong-Geun
    • Journal of Life Science
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    • v.24 no.7
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    • pp.791-797
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    • 2014
  • Sixty-two conserved orthologous groups (OGs) of proteins, in 63 prokaryotes and seven eukaryotes were analyzed to identify essential proteins in the mitochondria of eukaryotes, and their counterparts in prokaryotes. Twenty OGs were common in eukaryotic mitochondria, and all were translation related. Encephalitozoon cuniculi, an obligate parasitic eukaryote, shares no common mitochondrial OGs with the other 69 organisms. Seventeen conserved OGs were mitochondria related in the 69 organisms. Mitochondria related- and nonrelated-OGs were divided into prokaryotic genomes (p<0.001, paired t-test) unlike eukaryotic genomes in the distance value analysis. The most commonly conserved mitochondria-related OG was COG0048-KOG1750 (ribosomal small subunit S12), whereas it was COG0100-KOG0407 (ribosomal small subunit S11) in nonrelated OGs. These results could be applied in scientific research to determine phylogenetic relationships and in areas such as drug development.