• Title/Summary/Keyword: CO 중독

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A Clinical Study of Acute Carbon Monoxide Intoxication (급성 일산화탄소 중독증 환자의 임상적 고찰)

  • Choi, Kyong-Chan;Park, Mee-Yeung;Hah, Jung-Sang;Byun, Yeung-Ju;Park, Choong-Suh
    • Journal of Yeungnam Medical Science
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    • v.8 no.1
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    • pp.86-97
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    • 1991
  • To obtain the basic data of prognosis of acute carbon monoxide(CO) intoxication, one hundred and sixteen cases of CO intoxication defined by carboxyhemoglobin(COHb) and admitted via emergency room of Yeungnam University Hospital from Oct. '85 to April' 89 have been clinically analyzed and evaluated, including delayed postanoxic encephalopathy(DPE) and the following results were obtained. 1. The ratio of male to female was 1:1.5 and mental state was drowsy mostly(26.2% of 116 cases) 2. The more disturbed the mental state, the more decreased was the arterial pH and $PaCO_2$, which may be the result of metabolic acidosis. 3. The early laboratory findings in patients of CO intoxication were as follows : leukocytosis-65.5%, increase of hematocrit-23.3%, hyperglycemia-19.8%, increase of GPT-19.8% increase of creatinine-0.9%, and glucosuria-12.1%. 4. The early findings of EKG were abnormal in 35.3% : change of rhythm-25.0%, abnormal ST segment-15.5% (change of rhythm and abonormal ST segment-5.2%) but the conduction disorder was not present. 5. The abnormal EEG above mild degree was 93.1%, of which moderate was most frequent(80.2%). 6. The incidence of DPE was 7.8% among all admitted CO patients. DPE cases had long duration of exposure time(8 hours), severe leukocytosis(20,000) and an abnormal EEG(MA).

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Carboxyhemoglobin Dissociation at the Various Partial Pressures of Oxygen -Comparison between Adult and Fetal Bloods- (산소분압(酸素分壓)에 따른 Carboxyhemoglobin의 해리양상(解離樣相) -성인혈(成人血)과 태아혈(胎兒血)의 비교(比較)-)

  • Park, Byung-Joo
    • Journal of Preventive Medicine and Public Health
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    • v.15 no.1
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    • pp.145-151
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    • 1982
  • Breslau's report on the two stillbirths induced by illuminating gas poisoning made many investigators explore the hazards. of carbon monoxide(CO) poisoning to pregnancy. The pregnant woman, her fetus, and the newborn infant have been identified to be particularly vulnerable to CO even in low concentration. Several factors, such as placental barrier, membrane resistance of maternal and fetal red blood cells etc., were considered to be related to the delayed elimination of CO from fetus. Slower elimination of CO from fetus than from mother was confirmed in several in vivo studies. But there are few studies which have confirmed the difference of carboxyhemoglobin (HbCO) dissociation in adult and fetal bloods. Author investigated the effects of hemoglobin itself on the elimination of CO from mother and fetus. By observing the difference of CO dissociation from adult and fetal hemoglobin at the various partial pressures of oxygen, the author tries to suggest the base of the proper treatment measure for the CO poisoning of pregnant woman and newborn infant. The results were as follows: 1. The total hemoglobin amounts of adults and fetal bloods were $16.1{\pm}0.50gm%\;and\;15.7{\pm}0.32gm%$, respectively. The fetal hemoglobin proportions in adult and fetal bloods were $1.2{\pm}0.15%\;and\;72.7{\pm}3.01%$, respectively. 2. Adult and fetal bloods saturated by CO to 100% HbCO were exposed to ambient air$(21%\;O_2),\;100%\;O_2\;and\;3\;ATAO_2$. After 30 minutes exposure, the HbCO saturations of adult blood were 96.7%, 70.9%, and 52.8%, respectively, and those of fetal blood were 98.5%, 76.1%, and 62.2%, respectively. HbCO dissociation was proportional to the partial pressure of oxygen and the most marked dissociation was shown under 3 ATA $O_2$, HbCO dissociation of fetal blood was slower than that of adult blood in all conditions. According to the above results, it is possible that CO poisoning make more serious damage to the fetus and newborn infant than to the adult due to the delayed dissociation of HbCO. Thus in the treatment of CO poisoning of pregnant woman and newborn infant, hyperbaric oxygen therapy seems to be the most eflective treatment measure, but the duration of hyperbaric oxygenation should be lengthened accordingly.

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Bromide Concentration in Human Biological Samples Intoxicated by Methylbromide (Methylbromide에 중독된 인체시료 중 브롬이온의 함량)

  • You, Jae-Hoon;Lee, Sang-Ki;Jin, Kwang-Ho;In, Sang-Wban;Yoo, Young-Chan;Park, Sung-Woo
    • Analytical Science and Technology
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    • v.11 no.2
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    • pp.88-91
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    • 1998
  • Bromide($Br^-$) was separated and quantified with $2.8mM-NaHCO_3/2.2mM-Na_2CO_3$ by Ion Chromatography. Bromide was eluted at 8.9 min. and the detectetion limit was 2.5 ng. We compared with bromide concentration in normal or methylbromide intoxicated bloods and tissues. Bromide concentrations were 2.0~5.8 ppm in normal bloods and 1.0~5.3 ppm in normal tissues. In fatal cases of methylbromide intoxication, blood bromide concentrations (4 cases) of 74.2~139 ppm and tissue bromide concentration (1 case) of 76 (heart)~201 (lung) ppm were detected. In fatal cases, blood bromide concentrations. were 12~22 times higher than those of normal bloods.

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A Study on the Standard for Installation of Carbon Monoxide Detector in a Building (건축물내 일산화탄소 경보기 설치기준에 관한 연구)

  • Kang, Seung-Kyu;Choi, Kyung-Suhk
    • Journal of the Korean Institute of Gas
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    • v.12 no.4
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    • pp.1-7
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    • 2008
  • In the last five years, 36 people died and 79 were wounded because of carbon monoxide poisoning accident. A CO poisoning accident is higher than any other gas accident in the rate of deaths/incidents. Most of these CO poisoning accidents were caused by defective exhaust tube in the old gas boiler and multi-use facility. In this study, the spread mechanism of CO gas released from leakage hole of exhaust tube was analyzed by concentration measuring test. A CO gas leaked form exhaust tube in a building was the highest concentrated near the ceiling. CO alarm sets installation test confirmed that the alarm sets near the ceiling operated first, and the bottom and middle sets operated after $30{\sim}40$ minutes. Through these experiments, the reasonable installation location of CO alarm was made certain and suggested.

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2004년도 가스사고 현황

  • Korea LPGas Industry Association
    • LP가스
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    • s.95
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    • pp.55-57
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    • 2005
  • -대형사고(1급)는 2년연속 단 한건도 발생치 않아 -안전기기보급,안전공급계약제등 철저한 안전관리 추진결과 -가스보일러에 의한 CO중독사고로 인명피해 증가, 사용자 주의필요

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Influence of Intrauterine Position on Fetal Weight in Albino Rats Exposed to Carton Monoxide (일산화탄소중독 수태백서의 자궁내 착상위치가 태자의 발육에 미치는 영향)

  • Cho, Soo-Hun;Choi, Jang-Seok;Yun, Dork-Ro
    • Journal of Preventive Medicine and Public Health
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    • v.19 no.1 s.19
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    • pp.123-129
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    • 1986
  • Fetal weight data from 84 litters of Sprague-Dawley rats were statistically analyzed for the effect of position in the uterine horn on fetal weight. The standard score obtained from the mean weight and standard deviation of all fetuses in a uterine horn were studied for position effect. In control group, the heaviest fetus occupied the middle position with a progressive decrease in weights toward the ovarian and cervical ends of the horn. But the effect related to position for the fetal weight was not statistically significant. In contrast, rats acutely or chronically exposed to carbon monoxide showed statistically significant positional differences of fetal weight within the uterine horns. The findings that the intrauterine position effect on fetal weight which is not signicant in control group may act one of confounders at the situation of transplacental toxicological studios.

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A Study on the Relationship between Game Addiction and Social Stigma of the Youth outside school (학교 밖 청소년의 게임중독과 사회적 낙인감에 관한 상호관계 연구)

  • Moon, Jin-Young;Park, Ju-Won;Lee, Chang-Moon
    • Journal of Digital Convergence
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    • v.18 no.1
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    • pp.343-355
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    • 2020
  • The purpose of this study was to analyze the relationship between game addiction and social stigma of adolescents outside school. After examining the previous research focusing on the Public stigma & Self-stigma theory, We intended to examine how game addiction and social stigma affect each other over time, and the time causal relationship between the both. Using youth outside school panel 3rd, 4th, 5th data, This study analyzed the relationship between game addiction and social stigma of adolescents with school interruption longitudinally. The research method was analyzed by autoregressive cross-lagged model using two variables such as game addiction and social stigma using Amos25 program. The results showed that game addiction did not significantly affect social stigma at the next time, but social stigma had a significant effect on game addiction at the next time. Game addiction and social stigma have a strong auto-regressive effect, and the degree remains constant over time. Accordingly, this study suggested social co-prosperity, support from the local community, multidisciplinary viewpoints and cooperation between the public and private sectors.

An Experimental Study on Performance of Heatproof Silicon at the Connector of Boiler Exhaust Tube (배기통과 가스보일러 접속부의 내열실리콘 성능에 관한 실험적 연구)

  • Leem, Sa-Hwan;Lee, Jong-Rark;Kim, Cheol-Jin;Han, Gwi-Ho;Kim, Yong-Joo;Kim, Hee-Soo;Jang, Won-Suk;Lim, Cheong-Hwan
    • Journal of the Korean Institute of Gas
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    • v.11 no.4
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    • pp.91-97
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    • 2007
  • Recently, during the past five years, accidents of gas boiler using city gas have occurred 7.4 times more than those which use LP gas. The number of accidents has increased since the use of city gas boilers has increased. These boiler accidents resulted in 87% death from poisoning of CO, and casualty of the accidents was 4.3 times more than that of other types of accident. Hence this study makes the cause of accidents clear by separation the exhaust tube which is the cause of CO poisoning. Also, this study will establish the safety of heat-resistant silicon through testing the performance of heat-resistant silicon. The experiment showed that common silicon started hardening at $56^{\circ}C$ while the heat-resistant silicon did not begin carbonization until $606^{\circ}C$. Besides at the temperature of $150^{\circ}C$ which is the normal temperature of exhaust tube, common silicon leaked on the pneumatic test after deterioration, but the heat-resistant silicon maintained its original property. With these results, we judge that we can reduce the casualty by CO poisoning if we use the heat-resistant silicon to the connector of he exhaust tube.

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A case study of verifying a suicide by carbon monoxide intoxication committed by burning an ignition charcoal briquette (착화탄 연소에 의한 일산화탄소 중독사에서 자살입증에 관한 사례연구)

  • Sung, Tae-myung;Jo, Ju-ik;Ahn, Phil-sang
    • Analytical Science and Technology
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    • v.28 no.6
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    • pp.398-408
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    • 2015
  • Carbon monoxide (CO) intoxication, arising from CO from an ignited charcoal briquette (ICB), is a popular means of committing suicide in Korea. Most CO intoxications are related to suicide attempts; however, the possibility of a homicide disguised as a suicide cannot be ruled out. Therefore, forensic investigation of the deceased and the crime scene is crucial to confirm that the deceased committed suicide. Detection of the components of an ICB on the objects suspected of being contacted by the deceased, such as the hands, nostrils, and doorknobs, is essential for linking the crime scene to the victim in the case of suicides by ignited ICBs. The traces from an ICB were analyzed by investigating the morphological characteristics and obtaining elemental compositions. The ICBs were completely different from blackened wood, as detected by discriminant analysis with the elements of carbon and oxygen. We analyzed one case of CO intoxication to demonstrate an excellent procedure for verifying whether a suicide occurred with an ICB. We employed SEM-EDX for the analysis of an ICB, microscope-FT/IR and pyrolysis-GC/MS for a partly burnt resin-type substance, GC/MS for diphenhydramine (a sleeping drug), and GC/TCD for the CO-Hb level. We detected traces of an ICB on the hands, nostrils, and doorknobs, which were all discriminated into an ICB group. Detection of ICB traces from the nostrils could indicate that the deceased started the fire themselves to commit suicide. The partially burnt black material was analyzed as an acrylronitrilestyrene polymer, which is normally used to make bags for carrying or wrapping and could be assumed to have been used to transport the ICB. Diphenhydramine, a sleeping drug, was detected at a level of 2.3 mg/L in the blood, which was lower than that in fatal cases (8-31 mg/L; mean 16 mg/L). A CO-Hb level of 79% was found in the blood, which means that the cause of death was CO intoxication. The steps shown here could represent an ideal method for reaching a verdict of suicide by CO intoxication produced by burning an ICB in a sealed room or a car.

Gambling Behavior, Gambling-related Problem, and The Satisfaction with Life among the Residents Who Live in the Location of Casinos (카지노 유치지역 주민의 도박참여 및 도박중독 실태와 삶의 만족도: 강원도 폐광지역을 중심으로)

  • In-Hyae Yi
    • Korean Journal of Culture and Social Issue
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    • v.11 no.4
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    • pp.67-82
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    • 2005
  • The purpose of this study was to explore whether or not the increased availability of legalized gambling leads to increase in the prevalence of gambling-related problems, and the relationship between gambling behaviors and gambling-related problems and residents' perceptions of their own satisfaction with life among the residents who live at the location of casinos. Three casino communities, designated by a special law as run-down mining areas, were chosen for the survey research. One community consisted of two towns, Kohan and Sabuk in Chongsun county at which the casino is located. The other communities were Taeback city and other rural areas in Chongsun county. 559 samples from three communities completed self-administered questionnaires(gambling behavior participation, K-NODS, perceived impacts coward casino development, and scales of the satisfaction with life). Results were as follows; it was found that there was a positive relationship between gambling behaviors and gambling-related problems, and a negative relationship between gambling-related problems and the satisfaction with life. While residents who live Kohan and Sabuk community were likely to perceive negative impacts of the casino development, the residents in Taeback city were likely to perceive the casino development positively. It was found that the increased casino accessibility led co the increase in the gambling problems; the prevalence rates of pathological gambling in Kohan and Sabuk community were higher than both in Taebak city and in more rural areas in Chongsun county. The nagative impacts of legalized casino industry on community where the casino located were discussed.