• Journal of Korean Neurosurgical Society
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• 제29권3호
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• pp.430-433
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• 2000

Infantile myofibromatosis is a rare and benign myofibroblastic tumor that may occur in either solitary or multicentric form in the soft tissue of infants. A 13-month-old girl presented with a painless firm mass, measuring $2.5{\times}2.5cm$ in the right temporal area. Skull X-ray and CT scan revealed a well enhancing soft tissue tumor with a round skull defect and sclerotic margin. The tumor was totally excised with curettage of the skull defect followed by cranioplasty. Pathology was confirmed to be a solitary infantile myofibromatosis. We report this rare solitary infantile myofibromatosis of the temporal bone with review of the pertinent literature.

• Brain Tumor Research and Treatment
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• 제6권2호
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• pp.78-81
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• 2018

Gliosarcoma (GS), known as variant of glioblastoma multiforme, is aggressive and very rare primary central nervous system malignant neoplasm. They are usually located in the supratentorial area with possible direct dural invasion or only reactive dural thickening. However, in this case, GS was located in lateral side of left posterior cranial fossa. A 78-year-old man was admitted to our hospital with 3 month history of continuous dizziness and gait disturbance without past medical history. A gadolinium-enhanced MRI demonstrated $5.6{\times}4.8{\times}3.2cm$ sized mass lesion in left posterior cranial fossa, heterogeneously enhanced. The patient underwent left retrosigmoid craniotomy with navigation system. The tumor was combined with 2 components, whitish firm mass and gray colored soft & suckable mass. On pathologic report, the final diagnosis was GS of WHO grade IV. In spite of successful gross total resection of tumor, we were no longer able to treat because of the patient's rejection of adjuvant treatment. The patient survived for nine months without receiving any special treatment from the hospital.

• 대한수의학회지
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• 제63권4호
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• pp.32.1-32.4
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• 2023

Granular cell tumor was described in the testis of two rabbits. Testis from each rabbit was surgically removed and submitted for histopathological diagnosis. Both testes were about 2.0 cm in diameter, firm, and tan. Microscopically, testicular mass consisted of compact sheets of round to polygonal and occasional spindle-shaped cells. The neoplastic cells contain a large amount of eosinophilic granular material in the cytoplasm. The cytoplasmic eosinophilic granules were positive for periodic acid Schiff stain. Immunohistochemically, the neoplastic cells were immunoreactive to Melan-A and vimentin. Based on these results, the testicular mass was diagnosed as a granular cell tumor.

• 한국전통조경학회지
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• 제30권3호
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• pp.111-120
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• 2012

본 논문은 조경학분야의 주도로 수행된 원림유적의 문화재발굴 사업에 대한 일련의 성과를 다룬 것으로, 보길도 윤선도 원림(명승 제34호)의 낙서재 복원에서 귀암(龜巖) 발굴이 시사하는 역사적 가치와 발굴의 성과를 중심으로 기술하였다. 그 결과는 다음과 같이 요약될 수 있다. 발굴결과, 귀암은 낙서재 정북쪽으로 14.6m 지역에 매몰되어 있었고, 매몰면의 깊이는 10~50cm 정도의 표토층이 낙서재 쪽으로 오르막 경사를 두고 피복되어 있었다. 귀암 실측결과, 길이 360cm, 너비 270cm, 높이 95cm의 화강암으로 암석의 형태는 거북의 머리에 해당하는 북서편 모서리부분이 삼각형을 띄고 아래로 갈수록 좁아지는 형태로 $45^{\circ}$ 경사를 이루고 있었다. 머리 뒤쪽에는 귀갑 형태로 양쪽 홈이 파여 넓은 등판 형태를 보이고 있었다. 또한 남동방향으로 꼬리에 해당하는 부분이 돌출되어 있었다. 이 화강암은 거북의 머리와 꼬리부분이 인위적으로 조각되어 있는 것으로 보아 확연한 거북의 형상을 지니며 규모상으로 위치 변동 등의 교란 가능성이 적은 것으로 파악되었다. 낙서재 복원에 중요한 요소가 되는 거북 형상의 바위인 귀암은 윤위의 보길도지(甫吉島識)와 고산유고(孤山遺稿)에 기록된 사령(四靈)의 하나이며, 달 구경(玩月)의 장소로 기록되어 있으나, 그동안 실체를 확인할 길이 없었다. 이 귀암은 낙서재(樂書齋) 일원의 중요 지형지물로써 보길도지에 소은병(小隱屛)-낙서재(樂書齋)-귀암(龜巖)이 축선(軸線) 상에 있었던 것으로 추정되며, 고산의 손자인 이관(爾寬)의 건물 개축 시에도 앞 기둥을 이곳에 지지한 기록이 남아있어, 그동안 난항을 겪었던 낙서재 지역의 원형복원에 중요한 지표물로 그 가치가 있다. 또한, 원지반 확인결과, 표토층 135cm 아래 암반하단부에 단단한 원토양이 발견되어 현, 낙서재 지역의 원지반을 추정할 수 있는 근거가 확인되었다. 귀암은 이관의 건물 개축 당시 묻혔다는 기록을 끝으로 그동안 3차례 낙서재 지역 발굴조사에서도 확인되지 않았으나, 금번 연구의 결과로 최소한으로 보더라도 260여년 만에 그 실체가 드러나게 된 것이다. 이는 낙서재 지역의 원형복원과 조경학분야의 중요성을 제고할 수 있는 대표적 사례가 될 것이다. 향후 귀암의 보존처리와 고산의 시문에 나오는 사령의 의미해석 등에 대한 공간추정 등 연구가 계속되어야 할 것이다.

• 한국임상수의학회지
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• 제31권4호
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• pp.307-312
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• 2014

충북대학교 동물의료센터에 16년령 암컷 시츄견이 복부팽만과 배뇨, 배변곤란을 주증으로 내원하였다. 신체검사 시 복부에서 10 cm 가량의 종양이 촉진되었으며 방사선 상에서 확인되었고, 방광은 종양에 의해 배꼽 쪽으로 변위되어 있었다. 초음파 상에서 종양은 불균질한 실질과 국소적으로 무에코성 영역을 가지고 있었다. 혈액검사 소견상 혈소판증가증과 약한 호중구증가증이 나타났으며, 혈액화학치 검사 결과 ALP 상승을 확인할 수 있었다. 개복술을 시행하여 자궁경과 방광 사이의 $10.5{\times}9.6cm$ 크기의 단단한 종양이 요도를 포매하고 있는 것을 확인하고 주위조직과 둔성분리 후 절제하였다. 조직병리학적 검사와 면역화학 적 검사 결과 종양은 평활근육종으로 진단되었다. 수술 후 일주일 뒤 배뇨곤란을 주증으로 재 내원하였다. 배뇨곤란의 원인을 찾기 위하여 요도조영술을 실시하였으나 물리적인 폐색 등 특별한 원인을 찾을 수 없었다. 방광근과 방광조임근에 작용하는 몇몇 약물요법 등을 시행하였지만 반응이 없어 중장기의 보존요법이 지시되었으며 배뇨곤란 증상은 술 후 27일차에 갑작스럽게 호전되어 환자는 원활한 배뇨를 하게 되었다. 본 증례는 요도를 포매하고 있는 복강 내 종양의 수술 후 예후와 배뇨곤란과 같은 후유증을 나타낼 수 있음을 시사하고 있다.

• 한국임상수의학회지
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• 제33권1호
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• pp.74-79
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• 2016

A 7-year-old female Pointer dog with multiple masses in the axilla, mammary gland, and bladder was submitted to the Pathology Department of the College of Veterinary Medicine in the Jeju National University. Grossly, mass between right axilla and 1st mammary gland, $15{\times}10cm$ in size, was well delineated and firm, slightly soft center, oval shape. And masses in right 1st, 3rd and 5th mammary gland were well delineated and sulphur yellow in color on the cut-surface. Numerous round to oval shaped masses, 0.3 to 2 cm in diameter were existed in the lung. Urinary bladder mucosa had rough and thick and round to oval papillary masses, 0.1 to 2 cm in diameter, on surface. Microscopically, masses in right axilla, 1st mammary gland, lung and axillary lymph node were composed of poorly differentiated tubules originated from apocrine gland. Lining neoplastic epithelium showed high mitotic figures, typical apical secretory blebs, and PAS-positive diastase-resistant cytoplasmic granules. Masses in 3rd and 5th mammary gland were confirmed as mammary complex adenoma and simple adenoma respectively. The masses in the urinary bladder were covered with stratified transitional epithelium with marked cellular atypia and high mitotic figures. Some neoplastic cells showed focal invasion into substantia propria of bladder. Immunohistochemaically, neoplastic transitional epithelium demonstrated positive reactions for cytokeratin 7, AE1/AE3, and MNF116. Based on the gross, histopathologic and immunohistochemical characteristics, this dog was diagnosed as apocrine carcinoma, mammary gland tumor including simple adenoma and complex adenoma and bladder transitional cell carcinoma. And distant metastases of apocrine carcinoma in right axilla were observed in axillary lymph node and lungs. This is the first report for concurrent occurrence of apocrine carcinoma, mammary gland tumor, and transitional cell carcinoma in a same dog.

• 대한세포병리학회지
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• 제7권2호
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• pp.157-162
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• 1996

Fine needle aspiration(FNA) is an effective tool in diagnosing mammary carcinoma. We experienced 7 cases of histologically confirmed mammary mucinous carcinoma among 3,052 aspirated cases of breast from 1992 to 1996 in Asan Medical Center. The average age of the patient was 48(33-64) years. The mean size of the lesions was $1.6(0.7{\sim}3)cm$, and they were palpated as well-defined, firm to hard masses. The cytologic features that may be useful in making a FNA diagnosis of mucinous carcinoma of the breast were analysed. Mucinous background and tumor cell clusters with occasional single cells were observed in all cases. Among them, two cases showed abundant scattered single cells, whereas only few single cells were seen in the other two cases. Tumor cells exhibited mild pleomorphism in four cases and moderate pleomorphism in three cases. Nucleoli tended to be not prominent and are observed in three cases, rarely noted in other three cases and not seen in one. There was microcalcification in four cases(57%). In conclusion, mucinous background and clustered tumor cells showing mild to moderate pleomorphism with characteristic clinical findings allow us to diagnose mucinous carcinoma of the breast.

• 대한정형도수물리치료학회지
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• 제21권2호
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• pp.39-46
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• 2015

Background: The purpose of this study was to investigate the influence of short-term treadmill walking with high-heeled shoes on electromyography activities of the medial gastrocnemius, lateral gastrocnemius and tibialis anterior in healthy young females. Methods: Fifteen healthy females were recruited for this study. To measure muscle activation, the subjects were asked in random order to walk on a treadmill using either high-heeled shoes or barefoot conditions. The shoe heel height for high-heeled walking was 7 cm. The walking speed on the treadmill was 4 km/h, and the inclination rate of the treadmill was 10%. The subjects performed treadmill walking in the barefoot and high-heeled walking conditions for 5 minutes. Electromyography data were collected from the tibialis anterior, medial gastrocnemius, lateral gastrocnemius, and soleus on both firm and foam surfaces and during eyes-open and-closed conditions while standing. Results: Tibialis anterior activity was significantly different before and after the walking task while standing on a foam surface with eyes closed (p<.05). Conclusion: This finding suggests that the activity of the tibialis anterior may be lowered after high-heeled walking. Therefore, high-heeled shoes contribute to harmful effects at the ankle joints, increasing the risks of falling and musculoskeletal injury.

• Archives of Reconstructive Microsurgery
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• 제16권1호
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• pp.6-13
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• 2007

Purpose: To report the clinical results of the vascularized fibular graft in the treatment of intractable infected nonunion of femur. Materials and Methods: We reviewed 3 patients who were performed vascularized fibular graft in treated for intractable infected nonunion of femur. They had received an average of 5.6 times($4{\sim}8\;times$) surgical treatment at different hospitals. 1 case was of a infected nonunion in a fracture treated with internal fixation, the fracture having occurred after resection of a malignant tumor and transplantation of pasteurized autologous bone. 2 cases occurred after internal fixation in closed fractures. Surgical treatment was performed an average of 4 times($3{\sim}5\;times$) at our hospital and in all of the cases debridement of necrotic tissue and sequestrectomy. And vascularized fibular graft was performed. In all cases unilateral external fixation devices were used, of these, 1 case was changed into internal fixation. The final conclusion was made by assessment of functional outcomes and complications according to the standards of Paley. Results: As a result, in all of the cases bone union was achieved, and in the last follow up the functional results were excellent in 2 cases and good in 1 case. There were not presented leg length discrepancy of more than 2 cm, and further loss of knee joint motion. After previous treatment, average 23.3 months($16{\sim}30\;months$) was taken to eliminate infection and achieve complete bone union via vascularized fibular graft in our hospital. Conclusion: In treatment of intractable infected nonunion of femur, fairly good results can be expected after firm fixation, through debridement and vascularized fibular graft.

• 대한수의학회지
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• 제48권3호
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• pp.311-316
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• 2008

A 7-year-old female Shih Tzu dog with lots of masses in the whole mammary gland was presented to the surgery department of the Veterinary Teaching Hospital in the Cheju National University. After surgical excision, all mammary samples were referred to Pathology Department of Veterinary Medicine. Grossly, masses were measuring up to $6.5{\times}4{\times}1cm$ and on cut surface of masses in right 1st, 3rd, 4th, 5th and left 1st, 3rd, 4th, 5th mammary masses were well delineated and firm, sulphur yellow, solid round to oval shape. Microscopically, most neoplastic sweat glands were severely proliferated in dermis and subcutis. Most tubules were lined by round to oval shaped epithelium with eosinophilic cytoplasm, hyperchromatic nuclei with high mitotic figures and severe central necrosis. The neoplastic epithelium also had PAS-positive diastase-resistant cytoplasmic granules, but negative with Perls iron stain. The left 2nd mass was well delineated, and had several dark brown areas and yellowish white glittered areas. Mass was well circumscribed with dense connective tissue. Neoplastic areas contained irregular sized mammary gland with papillary grown luminal epithelial cells in single or double cells layer with mitotic figures and small amounts of proliferated myoepithelial cells. Proliferated myoepithelial cells also produced slightly basophilic mucinous materials. Based on the gross, histopathologic and special staining characteristics, this dog was diagnosed as 90% of apocrine sweat gland aenocarcinoma and 10% mammary. complex adenomas in mammary masses. In our best knowledge, this is the first report for concurrent occurrence of apocrine sweat gland adenocarcinoma and mammary gland complex adenoma in mammary masses of the same dog.