• 멤브레인
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• 제17권1호
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• pp.23-30
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• 2007

Polyethersulfone (PES)와 Bovine Serum Albumin (BSA) 용액으로 전기방사법을 이용하여 단백질 친화막을 제조하였다. 방사운전조건(방사용액의 농도, 전압, 방사속도, 방사거리)을 다양하게 조절하여 나노섬유의 크기를 관찰하였으며, 최적의 친화막 제조 조건을 확인할 수 있었다. XPS와 FT-IR로써 PES와 BSA의 결합을 확인하였으며, PES-BSA 나노섬유의 최적 방사 온도와 습도는 $20{\sim}22^{\circ}C$와 $45{\sim}55%$임을 알 수 있었다. 또한 PES 함량이 증가할수록 섬유의 크기가 증가하고, BSA의 경우 나노섬유의 크기에 큰 영향이 없음을 알았다. PES 7 wt%, BSA 0.7 wt%. Hexafluropropanol (HFP) 92.3 wt%의 용액을 이용하여 전압 10.0 kV, 방사거리 10 cm, 방사속도 1.0 mL/hr의 조건에서 방사한 경우 균일한 크기의 PES-BSA 나노섬유가 얻어졌다.

• Archives of Plastic Surgery
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• 제35권5호
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• pp.607-610
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• 2008

Purpose: Salivary duct carcinoma(SDC) is uncommon but high grade adenocarcinoma arising in the ductal epithelium of salivary glands. SDC is characterized by distinctive clinical and pathologic features. The most important histologic aspect of this neoplasm is its resemblance to ductal carcinoma of the breast. Clinically SDC is defined by cervical lymph node involvement and distant metastasis with a high rate of recurrence and mortality. We described some of the clinical and pathological features of SDC and the management using case report for our patient. Methods: We present a case of a 40-year-old male with 2-year history of a swelling arising in his left preauricular region. There was a single painless, firm and solid $2{\times}1.5cm$ mass in the left parotid area. Facial nerve function was intact and no cervical lymph node were palpable. In August 2005, we found out $1.7{\times}1.8cm$ sized cystic, nodular lesions that were located in the superficial lobe of left parotid gland through Computed tomography. And then superficial parotidectomy and postoperative radiation therapy were performed in Jan 2007. Results: Pathologically, the specimen were consisted of homogeneous, chondoid to myxoid type of tissues. It was yellow mass that has multiloculated cystic lesions. In postoperative PET(Positiron emission tomography) CT, there was no evidence of uptaking FDG(Fluorodeoxyglucose) into the deep layers of parotid gland and distant metastasis were not seen. Conclusion: Salivary duct carcinoma(SDC) is a rare but high grade adenocarcinoma related to pleomorphic adenocarcinoma. The prognosis of SDC can be different according to the type of tumor such as mucoepidermoid adenocarcinoma, adenoid duct carcinoma and acinar cell carcinoma. So we need to study more carefully for accurate diagnosis in early stage of diagnosis. Although radiotherapy has not yet proven to be a significant factor in overall survival, the combination of parotidectomy and postoperative radiation therapy can lead to more favorable results in treating of SDC.

• 대한관절경학회지
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• 제8권1호
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• pp.54-57
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• 2004

슬관절에 생긴 연골종은 드물게 보고되고 있어 저자들은 본원에서 경험한 1예의 임상양상과 조직학적 소견에 대해 보고하고자 하였다. 본 증례는 특별한 외상없이 발생한 슬관절 동통 및 종창을 주소로 내원한 38세 환자에 대한 것으로 슬관절의 전방 압통이 관찰되었으며 슬관절 전반에 경한 종창이 관찰되었다. 관절경하에서 종양을 절제한 결과 2 5 ${\times}$ 1.5 ${\times}$ 1 cm크기의 비교적 단단한 종괴였으며, 이는 중심부에 갈색을 갖는 부분적인 병변이 관찰되었고, 현미경학적으로 바깥쪽에 활액막이 얇게 덮여있는 초자 연골로 구성된 연골종으로 확인되었다.

• 한국임상수의학회지
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• 제30권5호
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• pp.399-402
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• 2013

8세령의 암컷 잡종 더러브렛 말이 4개월간의 눈물과 함께 좌측 상안검에 종괴가 형성되어 있었다. 편측성 외과적 수술을 실시하여 좌측 안구와 안검 종괴를 절제하여 진단 의뢰되었다. 육안적으로 종괴는 $6{\times}7{\times}2$ cm 크기이고 반구형의 모양이며 표면은 불규칙하게 거칠었다. 단면상에서 종괴는 단단하고 유백색조를 띠고 있었다. 병리조직학적으로 심하게 증식된 중층편평상피세포가 진피층으로 심하게 함입되어 있었으며, 무수히 많은 표피 능선(rete ridge)과 중층편평상피 섬(squamous islands)을 형성하고 있었다. 종양세포의 섬들은 중심부에 층판상의 암진주와 괴사된 세포 붕괴물을 가지고 전형적인 세포 간교(intercellular bridge)로 연결된 여러 층의 가시세포로 구성되어있었다. 이와 같은 결과를 토대로 본 예는 말의 상안검에서 발생한 중층편평상피 암종으로 진단하였다.

• 한국임상수의학회지
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• 제27권3호
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• pp.307-309
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• 2010

25년령의 암컷 캘리포니아 바다사자(Zalophus californianus)가 고령으로 인하여 분리 사육되고 있었다. 침울, 식욕부진, 쇠약, 체중감소 등의 임상증상을 보인 후 폐사하였고, 부검을 실시하였다. 육안적으로 양측 신장은 창백하고 직경 0.5-3 cm의 종양 결절이 다발성으로 관찰되었다. 간과 비장, 소장에서도 한계가 명료하고 크기가 다양하며 단단한 전이성 종양 결절이 다발성으로 존재하고 있었다. 본 예는 육안 및 병리조직학적 소견을 근거로 신장과 비장, 소장의 전이를 동반한 신장세포암종으로 진단할 수 있었다. 국내 캘리포니아 바다사자에서의 신장암의 보고는 드물며 향후 임상적으로 바다사자의 진료와 진단에 도움이 되고자 본 논문을 발표하는 바이다.

• 한국임상수의학회지
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• 제24권1호
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• pp.51-55
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• 2007

A 13-year-old male Yorkshire terrier was Presented with Persistent weight loss anorexia and dark brown urine of 3-month duration. On physical examination, a firm oval mass was palpated at left renal region. In hematology and blood chemistry, neutrophilia, anemia, thrombocytopenia and elevation of ALKP were found. Abdominal radiography, ultrasonography and ultrasound-guided percutaneous pyelogram revealed masses originated from left kidney, mildly dilated renal Pelvis and intact ureter. Urinalysis showed hematuria and proteinuria. Because the state of dog became deteriorated during transfusion and the frail renal tumor was suspected to be the cause of inflammation and anemia, nephrectomy was performed. Renal masses, approximately $2{\times}3cm\;and\;5{\times}4cm$ respectively in size, was surrounded by swollen and congested mesentery and ascites. Metastatic lesion was not found in other organs. During recovery, the dog showed cardiopulmonary arrest and did not respond to critical care. Histologically the kidney was affected by necrotic and hemorrhagic change. This hemangiosarcoma most likely arose from the renal parenchyma resulting In diffuse lesions in the kidneys thought to be the cause of chronic anorexia and weight loss.

• 한국동물위생학회지
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• 제34권4호
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• pp.403-407
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• 2011

This study describes a canine lymphosarcoma with a rapid proliferation and recurrence. A 4-year-old, male, Shih Tzu dog was examined for acute swelling mass. The mass had been identified since 3 months ago and enlarged $10{\times}7$ cm and located in the right axillary region. The surgical removal was recommended when patient visited veterinarian and the operation was conducted. The removed tumor was $11{\times}8{\times}7$ cm and firm, lobulated and white cut surface. Routine screening laboratory test was assessed with blood and radiological analysis. The metastasis sign was not detected on thoracic and abdominal radiography. Blood test revealed decreased lymphocytes. After surgical removal of the mass, microscopic histopathological examination was performed to determine the final diagnosis. Histopathologically, the tumors are characterized by the same histological features, including the presence of neoplastic cellular populations, and lymphocytes infiltration in varying proportions. Also, DNA was extracted and PCR analysis was employed to analyze the origin of tumor cells. T-cell specific nucleic acid fragments were specifically amplified by PCR. On the basis of the laboratory results, the tumor was diagnosed with canine T-cell lymphosarcoma. On the basis of our knowledge, this is the first report of canine T-cell lymphosarcoma in a Shih Tzu dog.

• 화훼연구
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• 제18권2호
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• pp.142-146
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• 2010

순백색 바탕에 자주색 화심이 있는 조생종 글라디올러스 '아리랑'이 1998년 국립원예특작과학원(구 원예연구소)에 의해 개발되었다. '아리랑'은 어두운 오렌지색 조생종 '아리안느'에 밝은 홍적색 대형종 국산품종인 '홍광'을 교배한 조합에서 선발되었다. 1993년에 교배하여 얻은 실생 종자를 파종, 1994년에 처음 선발하였으며 1998년까지 5년에 걸쳐 생육특성검정을 하였다. 아리랑은 밝은 백색바탕에 자주색 화심이 있는 절화용 품종으로 조생종이면서 꽃대가 휘지 않는 강한 초세를 갖고 있다. 따라서 여름철 노지 재배용으로 이용이 가능하다. 또한 장마철 습해에도 강하고 구근부패병에 강해 장마철 절화가 가능한 품종이다. 생육속도는 매우 빠르며 구근 번식력도 좋다. 아리랑의 여름철 개화소요일수는 75일 정도이며 구근 생산재배 시 품질 좋은 구근생산을 위해 생육 기간 중 추비를 1-2회 뿌려 주는 것이 좋다.

• 대한두경부종양학회지
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• 제40권1호
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• pp.33-36
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• 2024

Pleomorphic adenoma (PA) is a commonly occurring benign tumor originating in the salivary glands. The incidence is mostly in the parotid glands (85%) followed by minor salivary glands (10%). Pleomorphic adenoma from minor salivary glands of the lips is a rare neoplasm. Here, we present a case of a patient with PA in the upper lip, reporting a common neoplasm in a rare site. A 82-year-old male with a slowly progressing swelling that occurred 20years ago on the upper white lip. This tumor is not associated with pain and tenderness. The mass was about 1.5x1.5cm sized, circumscribed, sessile and firm on the external upper lip without oral side bulging (Fig. 1). The tumor was removed completely with a elliptical incision under local anesthesia. The encapsulated mass was measured 0.9x0.9x0.6cm. On histology, a well-circumscribed growth was seen comprising epithelial and stromal components. The epithelial component formed glandular structures lined by round-to oval cells having small nuclei, pink cytoplasm and myoepithelial basal cell layer while the stroma had a fibromyxoid appearance(Fig. 2). Postoperatively wound was well healed without recurrence after 6months. Pleomorphic adenoma of the upper lip is a rare neoplasm, especially not intraoral growth. For aesthetic good result, the mass was removed without hesitation. It is required a high index of suspicion and a long-term follow-up because it could recur and rarely be transformed into malignancy.

• 대한두경부종양학회지
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• 제22권1호
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• pp.36-39
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• 2006

The Neurofibroma is a benign neoplasm originating from neural tissue such as Schwann cell, fibroblast and peripheral fibroblast, which rarely converts to malignancy. About 25-45% of neurofibroma are located in head and neck, and the most common sites are lateral cervical region and mouth. Because of its high vascularity and invasion to the adjacent organs, surgical resection may be confronted and limited, moreover large neurofibroma can cause large defect that needs various kinds of flap. The factors related to clinically suspected malignancy are painlessness, abrupt increase in size, firm fixation, and central ulceration, although the malignancy rate of neurofibroma is low. The complete resection was failed several times at local clinic, the patient was transferred to our hospital. We have successfully removed the retroauricular neurofibroma using transposition flap & free skin graft on its large defects.