• Title/Summary/Keyword: CI-Model

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Measurement and analysis of indoor corridor propagation path loss in 5G frequency band (5G 주파수 대역에서의 실내 복도 전파 경로손실 측정 및 분석)

  • Kim, Hyeong Jung;Choi, Dong-You
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.26 no.5
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    • pp.688-693
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    • 2022
  • In this paper, channel propagation path loss was measured in building corridors for frequency bands of 3.7 GHz and 28 GHz, which are used in 5G mobile communication, and compared and analyzed with CI (Close-In) and FI (Floating-Intercept) channel models. To measure the propagation path loss, the measurement was performed while moving the receiver (Rx) from the transmitter (Tx) by 10 m. As a result of the measurement, the PLE (Path Loss Exponent) values of the CI model at 3.7 GHz and 28 GHz were 1.5293 and 1.7795, respectively, and the standard deviations were analyzed as 9.1606 and 8.5803, respectively. In the FI model, 𝛼 values were 79.5269 and 70.2012, 𝛽 values were -0.6082 and 1.2517, respectively, and the standard deviations were 5.8113 and 4.4810, respectively. In the analysis results through the CI model and the FI model, the standard deviation of the FI model is smaller than that of the CI model, so it can be seen that the FI model is similar to the actual measurement result.

Meta-analysis of Associations between the MDM2-T309G Polymorphism and Prostate Cancer Risk

  • Chen, Tao;Yi, Shang-Hui;Liu, Xiao-Yu;Liu, Zhi-Gang
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.9
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    • pp.4327-4330
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    • 2012
  • The mouse double minute 2 (MDM2) gene plays a key role in the p53 pathway, and the SNP 309T/G single-nucleotide polymorphism in the promoter region of MDM2 has been shown to be associated with increased risk of cancer. However, no consistent results were found concerning the relationships between the polymorphism and prostate cancer risk. This meta-analysis, covering 4 independent case-control studies, was conducted to better understand the association between MDM2-SNP T309G and prostate cancer risk focusing on overall and subgroup aspects. The analysis revealed, no matter what kind of genetic model was used, no significant association between MDM2-SNP T309G and prostate cancer risk in overall analysis (GT/TT: OR = 0.84, 95%CI = 0.60-1.19; GG/TT: OR = 0.69, 95%CI = 0.43-1.11; dominant model: OR = 0.81, 95%CI= 0.58-1.13; recessive model: OR = 1.23, 95%CI = 0.95-1.59). In subgroup analysis, the polymorphism seemed more likely to be a protective factor in Europeans (GG/TT: OR = 0.52, 95%CI = 0.31-0.87; recessive model: OR = 0.58, 95%CI = 0.36-0.95) than in Asian populations, and a protective effect of the polymorphism was also seen in hospital-based studies in all models (GT/TT: OR = 0.74, 95%CI = 0.57-0.97; GG/TT: OR = 0.55, 95%CI = 0.38-0.79; dominant model: OR = 0.69, 95%CI = 0.54-0.89; recessive model: OR = 0.70, 95%CI = 0.51-0.97). However, more primary studies with a larger number of samples are required to confirm our findings.

Change of Stages and Related Factors for Wearing of Hearing Protection Device among Noisy Workplace-workers (소음작업장 근로자의 청력보호구 사용단계와 관련요인)

  • Kim, Young-Mi;Jeong, Ihn-Sook
    • Journal of Korean Academy of Nursing
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    • v.40 no.5
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    • pp.736-746
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    • 2010
  • Purpose: This study was done to identify the distribution and related factors for stage of change for wearing hearing protection devices (HPDs) by workers in environments with high noise. Predictors of Use of Hearing Protection Model and Trans-theoretical Model were tested. Methods: The participants were 755 workers from 20 noisy work places in Busan and Gyeongnam. Data were collected from January to April 2008 using self-administered questionnaires, and analyzed using multiple logistic regression. Results: There were significant differences in social mode (OR=1.35, 95% CI: 1.06-1.73) between precontemplation/contemplation and preparation stage, in males (OR=2.36, 95% CI: 1.24-4.51), workers with high school education or less (OR=1.39, 95% CI: 1.28-2.78), shift workers (OR=1.50, 95% CI: 1.02-2.21), workers who previously worked in noisy places (OR=1.39, 95% CI: 1.20-2.34), and workers who had previous hearing examinations (OR=1.89, 95% CI: 1.25-2.85), in the social model (OR=1.59, 95% CI: 1.42-1.78), and self-efficacy (OR=1.05, 95% CI: 1.02-1.08) between workers in preparation and action stages, in length of time working in noisy work places (OR=2.26, 95% CI: 1.17-4.39), social model (OR=1.66, 95% CI: 1.33-2.08), and perceived benefit (OR=0.95, 95% CI: 0.93-0.97) between action and maintenance stage. Conclusion: Social model was a common factor showing differences between two adjacent stages for wearing HPDs. The results provide data for developing programs to encourage workers to wear HPDs and application of these programs in work settings.

Associations of Single Nucleotide Polymorphisms in miR-146a, miR-196a, miR-149 and miR-499 with Colorectal Cancer Susceptibility

  • Du, Wei;Ma, Xue-Lei;Zhao, Chong;Liu, Tao;Du, Yu-Liang;Kong, Wei-Qi;Wei, Ben-Ling;Yu, Jia-Yun;Li, Yan-Yan;Huang, Jing-Wen;Li, Zi-Kang;Liu, Lei
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.2
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    • pp.1047-1055
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    • 2014
  • Background: MicroRNAs (miRNAs) are an abundant class of endogenous small non-coding RNAs of 20-25 nucleotides in length that function as negative gene regulators. MiRNAs play roles in most biological processes, as well as diverse human diseases including cancer. Recently, many studies investigated the association between SNPs in miR-146a rs2910164, miR-196a2 rs11614913, miR-149 rs229283, miR-499 rs3746444 and colorectal cancer (CRC), which results have been inconclusive. Methodology/Principal Findings: PubMed, EMBASE, CNKI databases were searched with the last search updated on November 5, 2013. For miR-196a2 rs11614913, a significantly decreased risk of CRC development was observed under three genetic models (dominant model: OR = 0.848, 95%CI: 0.735-0.979, P = 0.025; recessive model: OR = 0.838, 95%CI: 0.721-0.974, P = 0.021; homozygous model: OR = 0.754, 95%CI: 0.627-0.907, P = 0.003). In the subgroup analyses, miR-$196a2^*T$ variant was associated with a significantly decreased susceptibility of CRC (allele model: OR = 0.839, 95%CI: 0.749-0.940, P = 0.000; dominant model: OR = 0.770, 95%CI: 0.653-0.980, P = 0.002; recessive model: OR = 0.802, 95%CI: 0.685-0.939, P = 0.006; homozygous model: OR = 0.695, 95%CI: 0.570-0.847, P = 0.000). As for miR-149 rs2292832, the two genetic models (recessive model: OR = 1.199, 95% CI 1.028-1.398, P = 0.021; heterozygous model: OR = 1.226, 95% CI 1.039-1.447, P = 0.013) demonstrated increased susceptibility to CRC. On subgroup analysis, significantly increased susceptibility of CRC was found in the genetic models (recessive model: OR = 1.180, 95% CI 1.008-1.382, P = 0.040; heterozygous model: OR = 1.202, 95% CI 1.013-1.425, P = 0.013) in the Asian group. Conclusions: These findings supported that the miR-196a2 rs11614913 and miR-149 rs2292832 polymorphisms may contribute to susceptibility to CRC.

Text Steganography Based on Ci-poetry Generation Using Markov Chain Model

  • Luo, Yubo;Huang, Yongfeng;Li, Fufang;Chang, Chinchen
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.10 no.9
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    • pp.4568-4584
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    • 2016
  • Steganography based on text generation has become a hot research topic in recent years. However, current text-generation methods which generate texts of normal style have either semantic or syntactic flaws. Note that texts of special genre, such as poem, have much simpler language model, less grammar rules, and lower demand for naturalness. Motivated by this observation, in this paper, we propose a text steganography that utilizes Markov chain model to generate Ci-poetry, a classic Chinese poem style. Since all Ci poems have fixed tone patterns, the generation process is to select proper words based on a chosen tone pattern. Markov chain model can obtain a state transfer matrix which simulates the language model of Ci-poetry by learning from a given corpus. To begin with an initial word, we can hide secret message when we use the state transfer matrix to choose a next word, and iterating until the end of the whole Ci poem. Extensive experiments are conducted and both machine and human evaluation results show that our method can generate Ci-poetry with higher naturalness than former researches and achieve competitive embedding rate.

Association between the NQO1 C609T Polymorphism with Hepatocellular Carcinoma Risk in the Chinese Population

  • Zhao, Hong;Zou, Li-Wei;Zheng, Sui-Sheng;Geng, Xiao-Ping
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.5
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    • pp.1821-1825
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    • 2015
  • Background: Associations between the NQO1 C609T polymorphism and hepatocellular carcinoma (HCC) risk are a subject of debate. We therefore performed the present meta-analysis to evaluate links with HCC susceptibility. Materials and Methods: Several major databases (PubMed, EBSCO), the Chinese national knowledge infrastructure (CNKI) and the Wanfang database were searched for eligible studies. Crude odds ratios (ORs) with 95% confidence intervals (CIs) were used to measure the strength of associations. Results: A total of 4 studies including 1,325 patients and 1,367 controls were identified. There was a significant association between NQO1 C609T polymorphism and HCC for all genetic models (allelic model: OR=1.45, 95%CI=1.23-1.72, p<0.01; additive model: OR=1.96, 95%CI=1.57-2.43, p<0.01; dominant model: OR=1.62, 95%CI=1.38-1.91, p<0.01; and recessive model: OR=1.53, 95%CI=1.26-1.84, p<0.01). On subgroup analysis, similarly results were identified in Asians. For Asians, the combined ORs and 95% CIs were (allelic model: OR=1.50, 95%CI=1.24-1.82, p<0.01; additive model: OR=2.11, 95%CI=1.48-3.01, p<0.01; dominant model: OR=1.69, 95%CI=1.42-2.02, p<0.01; and recessive model: OR=1.59, 95%CI=1.16-2.19, p<0.01). Conclusions: The current meta-analysis suggested that the NQO1 C609T polymorphism could be a risk factor for developing HCC, particularly in the Chinese population.

Predictors of Stage of Change for Exercise Behaviors among Middle Aged Women based on the Tanstheoretical Model (범이론적 모형(Transtheoretical Model)에 근거한 중년여성의 운동행동 변화단계 예측요인)

  • Lee, Yun-Mi
    • Korean Journal of Adult Nursing
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    • v.16 no.3
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    • pp.421-431
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    • 2004
  • Purpose: The study was performed to investigate the predictors associated transition with each stage of exercise behavior based to the Transtheoretical Model, and to provide basic data for exercise behavior programs for middle aged women. Methods: The subjects consisted of 434 women residing in B city by convenience sampling. The collected data were analyzed with multiple logistic regression using SPSS/WIN program. Results: The predictors of transition from precontemplation to contemplation were consciousness raising(OR=2.095, 95% CI: 1.305-3.363), Reinforcement management(OR= 1.903, 95% CI: 1.107-3.271), Stimulus control (OR=2.176, 95% CI:1.239-3.820), Menstrual status (OR=5.327, 95% CI: 1.110-25.562). The predictors of transition from contemplation to preparation were Helping relationship(OR= 1.671, 95% CI: 1.065-2.662), Pros(OR=2.500, 95% CI: 1.254-4.982), Perceived Health status (OR=.178, 95% CI: .041-.770). The predictor of transition from preparation to action was Stimulus control(OR=1.918, 95% CI: 1.103- 3.336). The predictors of transition from action to maintenance were Consciousness raising(OR= 1.939, 95% CI: 1.031-3.647), Dramatic relief (OR=2.249, 95% CI: 1.025-4.931). Conclusions: Adequate examination on the factors, which can predict the transitional stages of change exercise behaviors among middle aged women, which is presented in this study. The results of this study will become the pillar of exercise intervention program planning and application.

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Genetic Polymorphisms of TCF7L2 Lack Influence on Risk of the Polycystic Ovary Syndrome - a Systemic Analysis

  • Lin, Lin;Yang, Jing;Ding, Yan;Wang, Jing;Ting, Liu
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.7
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    • pp.3331-3333
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    • 2014
  • Background: The results of previous researches that analyzed the association between genetic polymorphisms of transcription factor-7-like 2 (TCF7L2, rs7903146) and polycystic ovary syndrome (PCOS) were conflicting. Current systematic analysis was conducted to re-explore this association using updated materials. Materials and Methods: The PubMed database was used for data collection and the final search was conducted on January 3, 2014. For TCF7L2 rs7903146, a non-signficiant slight increase in risk of PCOS development was observed under three genetic models (dominant model: OR=1.06, 95%CI: 0.93-1.21, p>0.05; recessive model: OR=1.12, 95%CI: 0.87-1.43, p> 0.05; homozygous model: OR=1.14, 95%CI: 0.87-1.47, p>0.05). In the subgroup analyses in Asian group, allele susceptibility of PCOS was calculated (allele model: OR=1.00, 95%CI: 0.74-1.35, p>0.05; dominant model: OR=0.98, 95%CI: 0.71-1.35, p>0.05; recessive model: OR=1.79, 95%CI: 0.33-9.84, p>0.05; homozygous model: OR=1.78, 95%CI: 0.32-9.80, p>0.05), the differences were again not statistically significant. Conclusions: The findings of this systemic analysis suggest that the polymorphism of TCF7L2 rs7903146 may not be associated with the susceptibility to PCOS.

A Genetic Variant in MiR-146a Modifies Digestive System Cancer Risk: a Meta-analysis

  • Li, Ying-Jun;Zhang, Zhen-Yu;Mao, Ying-Ying;Jin, Ming-Juan;Jing, Fang-Yuan;Ye, Zhen-Hua;Chen, Kun
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.145-150
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    • 2014
  • MicroRNAs (miRNAs) negatively regulate gene expression and act as tumor suppressors or oncogenes in oncogenesis. The association between a single nucleotide polymorphism (SNP) in miR-146a rs2910164 and susceptibility to digestive system cancers was inconsistent in previous studies. In this study, we conducted a literature search of PubMed to identify all relevant studies published before August 31, 2013. A total of 21 independent case-control studies were included in this updated meta-analysis with 9,558 cases and 10,614 controls. We found that the miR-146a rs2910164 polymorphism was significantly associated with decreased risk of digestive system cancers in an allele model (OR=0.90, 95%CI 0.87-0.94), homozygote model (OR=0.84, 95%CI 0.77-0.91), dominant model (OR=0.90, 95%CI 0.84-0.96), and recessive model (OR=0.85, 95%CI 0.79-0.91), while in a heterozygous model (OR = 0.99, 95% CI 0.89-1.11) the association showed marginal significance. Subgroup analysis by cancer site revealed decreased risk in colorectal cancer above allele model (OR=0.90, 95%CI 0.83-0.97) and homozygote model (OR=0.85, 95%CI 0.72-1.00). Similarly, decreased cancer risk was observed when compared with allele model (OR=0.87, 95%CI 0.81-0.93) and recessive model (OR=0.81, 95%CI 0.72-0.90) in gastric cancer. When stratified by ethnicity, genotyping methods and quality score, decreased cancer risks were also observed. This current meta-analysis indicated that miR-146a rs2910164 polymorphism may decrease the susceptibility to digestive system cancers, especially in Asian populations.

The effect of blood cadmium levels on hypertension in male firefighters in a metropolitan city

  • Ye-eun Jeon;Min Ji Kim;Insung Chung;Jea Chul Ha
    • Annals of Occupational and Environmental Medicine
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    • v.34
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    • pp.37.1-37.15
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    • 2022
  • Background: This study investigated the effect of dispatch frequency on blood cadmium levels and the effect of blood cadmium levels on hypertension in male firefighters in a metropolitan city. Methods: We conducted a retrospective longitudinal study of male firefighters who completed the regular health checkups, including a health examination survey and blood cadmium measurements. We followed them for 3 years. To investigate the effect of dispatch frequency on blood cadmium levels and the effect of blood cadmium levels on hypertension, we estimated the short-term (model 1) and long-term (model 2) effects of exposure and hypothesized a reversed causal pathway model (model 3) for sensitivity analysis. Sequential conditional mean models were fitted using generalized estimating equations, and the odds ratios (ORs) and the respective 95% confidence intervals (CIs) were calculated for hypertension for log-transformed (base 2) blood cadmium levels and quartiles. Results: Using the lowest category of dispatch frequency as a reference, we observed that the highest category showed an increase in blood cadmium levels of 1.879 (95% CI: 0.673, 3.086) ㎍/dL and 0.708 (95% CI: 0.023, 1.394) ㎍/dL in models 2 and 3, respectively. In addition, we observed that doubling the blood cadmium level significantly increased the odds of hypertension in model 1 (OR: 1.772; 95% CI: 1.046, 3.003) and model 3 (OR: 4.288; 95% CI: 1.110, 16.554). Using the lowest quartile of blood cadmium levels as a reference, the highest quartile showed increased odds of hypertension in model 1 (OR: 2.968; 95% CI: 1.121, 7.861) and model 3 (OR: 33.468; 95% CI: 1.881, 595.500). Conclusions: We found that dispatch frequency may affect blood cadmium levels in male firefighters, and high blood cadmium levels may influence hypertension in a dose-response manner.