• 디지털융복합연구
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• 제13권9호
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• pp.201-208
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• 2015

SNS와 페이스북과 같은 서비스가 대중화되면서 마이크로블로그와 같은 작은 크기의 빅 데이터 사용이 증대되고 있다. 그러나, 현재까지 작은 크기의 빅 데이터의 탐색 결과의 정확성과 계산비용은 미해결 상태로 남아있다. 본 논문에서는 빅 데이터 환경에서 마이크로블러그와 같은 작은 크기의 텍스트 정보의 탐색 속도를 향상시키기 위한 확률기반의 서브넷 선택 기법을 제안한다. 제안 기법은 데이터의 속성 정보에 확률값을 부여하여 서브넷을 구성하여 데이터 탐색 속도를 높였다. 또한, 제안 기법은 분산된 데이터를 손쉽게 접근하기 위해서 서브넷을 구성하는 데이터 의확률값 간 연계 정보를 쌍으로 처리함으로써 데이터의 접근성을 향상시켰다. 실험결과, 제안 기법은 CELF 알고리즘보다 평균 6.8% 높은 탐지율을 보였으며, 처리시간은 평균 8.2% 단축시켰다.

• Journal of Information Processing Systems
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• 제10권3호
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• pp.471-482
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• 2014

Influence maximization is an important problem of finding a small subset of nodes in a social network, such that by targeting this set, one will maximize the expected spread of influence in the network. To improve the efficiency of algorithm KK_Greedy proposed by Kempe et al., we propose two improved algorithms, Lv_NewGreedy and Lv_CELF. By combining all of advantages of these two algorithms, we propose a mixed algorithm Lv_MixedGreedy. We conducted experiments on two synthetically datasets and show that our improved algorithms have a matching influence with their benchmark algorithms, while being faster than them.

• 한국동물학회지
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• 제37권1호
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• pp.12-18
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• 1994

The prothoracicotropic hormone (PTTH) produced by the neurosecretory cells in insects is involved in molting and metamorphosis by activating the prothoracic frins) glands to secrete ecdysone (or related ecdvsteroidsl. In the present study, the small PTTH-like gene was isolated by screening of CDNA library using the bombvxin (corresponding to small PTTH in Bombvx moril gene probe in Drosophilo melonogaster. It showed 50-6096 sequence homology to bombyxin gene. The expression patterns of this gene showed developmental stage- and tissue-dependent manners. The mRNA was detected only in the late third instar larval-prepupa which is stases showing the highest hormonal activity to secrete ecdysteroids, and detected in the brain pan of the Isle third instar lanrae.

• 대한치매학회지
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• 제17권4호
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• pp.131-136
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• 2018

Alzheimer's disease (AD) related genes have been elucidated by advanced genetic techniques. Familial autosomal dominant AD genes founded by linkage analyses are APP, PSEN1, PSEN2, ABCA7, and SORL1. Genome-wide association studies have found risk genes such as ABCA7, BIN1, CASS4, CD33, CD2AP, CELF1, CLU, CR1, DSG2, EPHA1, FERMT2, HLA-DRB5-HLA-DRB1, INPP5D, MEF2C, MS4A6A/MS4A4E, NME8, PICALM, PTK2B, SLC24A4, SORL1, and ZCWPW1. ABCA7, SORL1, TREM2, and APOE are proved to have high odds ratio (>2) in risk of AD using next generation sequencing studies. Thanks to the promising genetic techniques such as CRISPR-CAS9 and single-cell RNA sequencing opened a new era in genetics. CRISPR-CAS9 can directly link genetic knowledge to future treatment. Single-cell RNA sequencing are providing useful information on cell biology and pathogenesis of diverse diseases.

• Journal of Contemporary Eastern Asia
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• 제19권2호
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• pp.40-60
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• 2020

Among Filipino entertainers in Japan, trans women (transgender women) or transpinay (Filipino trans woman) entertainers remain understudied compared to cisgender women. Though the number of entertainers has declined, transpinay entertainers remain relevant as transgender issues continue to be salient globally. This study explains the gendered experiences of the transpinay migrants, particularly in entertainment work and their relationships, which are different from cisgender Filipino women entertainers' experiences. Using grounded theory and drawing on concepts of performativity in interactions to analyze the narratives of transpinay entertainers, I delve into how transpinay entertainers negotiate their gender and migrant identities as they establish professional and personal relationships. Moreover, the transpinays' entertainment work is a significant contributing factor to their sense of belonging in Japan, as they form relationships with colleagues, clients, and partners who support them and, thereby, sustain their lifestyles as trans women. The transpinay entertainers' flows of migration between Japan and the Philippines reveal that they embrace various aspects of social remittances and use them to their advantage to create and enhance their transpinay identity in Japan. By examining the transpinays' migrant experiences, this study aims to elucidate the gendered experiences of transpinay entertainers, which involve significant negotiations in their migration pathways notably different from cisgender Filipino women entertainers, reveal resilience.

• Genomics & Informatics
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• 제11권3호
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• pp.149-154
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• 2013

Liver enzyme elevations, as an indicator of liver function, are widely associated with metabolic diseases. Genome-wide population-based association studies have identified a genetic susceptibility to liver enzyme elevations and their related traits; however, the genetic architecture in childhood remains largely unknown. We performed a genome-wide association study to identify new genetic loci for liver enzyme levels in a Korean childhood cohort (n = 484). We observed three novel loci (rs4949718, rs80311637, and rs596406) that were multiply associated with elevated levels of alanine transaminase and aspartate transaminase. Although there are some limitations, including genetic power, additional replication and functional characterization will support the clarity on the genetic contribution that the ST6GALNAC3, ADAMTS9, and CELF2 genes have in childhood liver function.

• Korean Chemical Engineering Research
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• 제61권2호
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• pp.265-272
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• 2023

목질계 바이오매스는 조성분간의 결합이 치밀하고 높은 함량의 리그닌을 포함하여 전처리 공정이 필수적이다. 전처리 용매 중 테트라하이드로퓨란(THF)은 유기용매로 재사용이 가능하다는 장점이 있다. THF는 가격이 저렴하고 다양한 반응 조건에서 선택적으로 리그닌을 제거하고 물 혹은 이온성 액체와 공용매로 사용된다. 수산화 나트륨(Sodium hydroxide)은 바이오매스 내 ether결합을 파괴하여 리그닌을 우선적으로 용해시키며 셀룰로오스와 헤미셀룰로오스의 표면적을 확장시키는 역할을 한다. 본 연구에서는 NaOH/THF 공용매 전처리 공정을 적용하여 효과적 리그닌을 제거를 위한 전처리 특성을 파악하고 후속 공정인 산촉매 전환 공정을 통해 최적의 레불린산 전환 수율을 얻었다. 전처리 공정은 NaOH/THF 공용매 비율을 16가지 부피 비율로 수행되었으며 반응조건은 180℃에서 60분으로 고정하였다. 최적의 공용매 조건은 NaOH(5 wt%)/THF 공용매 90:10(v/v%)이였으며 76.8% 글루칸을 수득과 함께 90.1%의 리그닌을 제거하였다. 전처리 후속 공정인 산촉매 전환 공정은 반응시간 30~90분, 반응온도 160~200 ℃로 수행하였을 때, 산촉매 전환 공정의 최적 조건은 180 ℃에서 반응시간 60분이었며, 이 때의 레불린산 전환수율은 84.7%이다.