• Toxicological Research
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• 제29권2호
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• pp.99-106
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• 2013

Clostridium difficile infection (CDI) has become a significant threat to public health. Although broad-spectrum antibiotic therapy is the primary treatment option for CDI, its use has evident limitations. Probiotics have been proved to be effective in the treatment of CDI and are a promising therapeutic option for CDI. In this study, 4 strains of lactic acid bacteria (LAB), namely, Lactobacillus rhamnosus (LR5), Lactococcuslactis (SL3), Bifidobacterium breve (BR3), and Bifidobacterium lactis (BL3) were evaluated for their anti-C. difficile activity. Co-culture incubation of C. difficile ($10^6$ and $10^{10}$ CFU/ml) with each strain of LAB indicated that SL3 possessed the highest antimicrobial activity over a 24-hr period. The cell-free supernatants of the 4 LAB strains exhibited $MIC_{50}$ values between 0.424 mg/ml (SL3) and 1.318 (BR3) mg/ml. These results may provide a basis for alternative therapies for the treatment of C. difficile-associated gut disorders.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제29권2호
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• pp.54-61
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• 2018

Objectives: This study was conducted to investigate the effectiveness of a class-based school violence prevention program for elementary school student. Methods: 29 students were assigned to the school violence prevention program of 8 sessions, 28 students have been assigned to the control group. We assessed participants at baseline and post-intervention, through their self-report questionnaires such as Children's Depression Inventory (CDI), Strengths and Difficulties Questionnaire and school violence experience, awareness about school violence, and coping ability to school violence. We compared the baseline and post-intervention result of each group and compared the post-test scores between the intervention group and the control group. Results: Comparing the intervention group and the control group, the post-intervention CDI total score and the awareness about school violence showed significant improvement in the intervention group. When compared according to gender, male students' perception of school violence was improved, and female students showed significant differences in CDI scores. Conclusion: The CDI total scores and the perception of school violence were improved in the intervention group compared to the control group. And there are differential pattern of intervention effects according to gender. These findings have important implications to develop effective violence prevention programs.

• Carbon letters
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• 제15권1호
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• pp.38-44
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• 2014

This paper reports the effect of adding reduced graphene oxide (RGO) as a conductive material to the composition of an electrode for capacitive deionization (CDI), a process to remove salt from water using ionic adsorption and desorption driven by external applied voltage. RGO can be synthesized in an inexpensive way by the reduction and exfoliation of GO, and removing the oxygen-containing groups and recovering a conjugated structure. GO powder can be obtained from the modification of Hummers method and reduced into RGO using a thermal method. The physical and electrochemical characteristics of RGO material were evaluated and its desalination performance was tested with a CDI unit cell with a potentiostat and conductivity meter, by varying the applied voltage and feed rate of the salt solution. The performance of RGO was compared to graphite as a conductive material in a CDI electrode. The result showed RGO can increase the capacitance, reduce the equivalent series resistance, and improve the electrosorption capacity of CDI electrode.

• 대한수의학회지
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• 제45권3호
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• pp.423-427
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• 2005

Color Doppler imaging (CDI) was carried out to evaluate the anesthetics effect on ophthalmic circulation using CDI-derived resistive index (RI) values. CDI was preformed on 24 dogs, and RI values were calculated for the medial long posterior ciliary artery (mLPCA) and ophthalmic artery (OA) before and after administration of anesthetics. After administration of benoxinate or acepromazine, a significant change of the mLPCA RI was not found. But, a significant decrease of the RI following ketamine (p < 0.001) or xylazine (p < 0.01) administration could be observed as compared with the self-control. Mean RI value of OA also showed this same trend. Intraocular pressure was significantly decrease following benoxinate (p < 0.01), acepromazine (p < 0.01), and xylazine (p < 0.001) administration within normal range. The results suggest that some anesthetics influence on ophthalmic vascular resistance. Therefore, chemical restraint was carefully used in clinical application of CDI-derived RI measurement. Particularly, benoxinate and acepromazine is useful chemical restraint without a change of the ophthalmic vascular resistance.

• 멤브레인
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• 제29권5호
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• pp.276-283
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• 2019

본 논문에서는 축전식 탈염 공정에서 파울링 현상의 확인과 파울링의 제거공정 조건을 확립하는 연구를 진행하였다. 공급액에 첨가된 파울링 유발 물질인 Humic acid sodium salt (HA)의 농도는 5, 10, 15 mg/L이었다. 주어진 일반의 흡/탈착 조건에서 파울링의 발생은 시간이 지남에 따라 흡착과 탈착 농도의 증가로 확인할 수 있었다. 파울링 현상을 제거하기 위해 흡착 및 탈착에서의 전압과 시간을 변경하였다. 이로부터 흡착 조건 1.2 V/5 min, 탈착 조건 -3 V/2 min에서 파울링 제거를 확인하였다.

• Korean Journal of Acupuncture
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• 제32권2호
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• pp.41-50
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• 2015

Objectives : In this study we investigated characteristics of eight extra meridians based on the chapter of Pyoung Gi Kyoung Pal Maek Byoung(PGKPMB) of the Pulse Classic(Maijing; PC) and the 27, 28, and $29^{th}$ question of the Classic of Difficult Issues(Nanjing; CDI). Methods : We searched out the contents of eight extra meridians in historical background, the principal and circulation of eight extra meridians, and the symptoms and pulse diagnosis of eight extra meridians on the PGKPMB of the PC and the 27, 28, and $29^{th}$ question of the CDI. Results and Conclusions : About development of eight extra meridians, content which was scattered in the CDI was supplemented and developed in the CDI. Also taking over the content in the CDI, the meaning of the eight extra meridians was expanded and supplemented in the PC. In the PC, the mechanism about symptom of eight extra meridians especially has been described. Also materialization of symptom which linked to pathogenic pulse of eight extra meridians had a great impact on future generation.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2015년도 학술발표회
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• pp.603-603
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• 2015

모든 외재적 형식의 가뭄을 모니터링하고 예측 및 평가하기 위해서는 가뭄지수가 필수적 요소로써 이용된다. 일반적으로 가뭄지수는 단일지수(single index), 다중지수(multiple index), 복합지수(composite index)로 분류되며 대부분 강수량, 유출량, 토양 수분량 등과 같은 하나의 변수만을 사용하는 단일지수이다. 가뭄지수는 가뭄평가에 있어서 각각의 장단점이 있다. 하나의 변수를 사용하는 가뭄지수는 계산이 간편하지만 가뭄의 물리적 특성을 정확하게 반영할 수 없기 때문에 신뢰할 수 있는 가뭄평가에 충분하지 않다. CDI(Composite Drought Index)는 PDSI(Palmer Drought Index), ADI(Aggregate Drought Index), SWSI(Surface Water Supply Index)와 같은 다중지수의 개념을 착안하여 고안되었으며, 모든 가뭄 형태(농업적 수문학적 기상학적)와 관련된 강우량, 유출량, 정규식생지수(NDVI)를 변수로써 사용하였다. NDVI는 MODIS(Moderate resolution imaging spectroradiometer)에서 제공하는 16일 간격의 위성자료를 이용하여 계산되었고 이와 시간 스케일을 맞추기 위해 나머지 두 변수 또한 16일 시계열을 사용하였다. CDI는 (1)각 변수들의 시계열을 행렬로 나타내고 (2)이것을 정규화하여 무차원 행렬로 변환한 후 (3)연구 지역의 최고습윤상태(most wet condition) 및 최고건조상태(most dry condition)의 차이값을 기반으로 하여 산정된다. 본 연구에서는 상대적으로 다른 유역에 비해 장기적이고 연속적인 자료를 확보할 수 있으며 농경지와 산림지역 비율이 높은 낙동강 유역을 대상유역으로 설정하였으며, 2001-2013년 기간의 자료를 이용하였다. 그 결과 연구 기간 중 실제 발생했던 가뭄을 반영하는 것을 확인하였다. 또한 CDI는 다양한 변수의 활용으로 가뭄의 물리적 특성의 반영이 가능하며 연구 지역의 기상 조건에 직접적으로 관련된 결과를 나타낸다. 자료의 가용성에 따라 적용범위가 제한적일 수 있으나 입력값으로 사용된 변수와 시계열을 편의와 효율에 따라 유연하게 적용할 수 있다. 따라서 CDI는 농업적, 수문학적, 기상학적 가뭄의 모든 관점을 통합하는 실용적 가뭄지수로써 사용될 수 있는 가능성을 포함하고 있다.

• 적정기술학회지
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• 제6권2호
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• pp.183-189
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• 2020

개발도상국은 빈약한 식수 인프라로 인해 식수공급에 어려움을 겪고 있으며 식수가 공급되지 않는 지역에서는 지하수를 주된 식수원으로 이용하는 경우가 많다. 하지만 지하수의 경우 다양한 오염원에 노출되어 있고 이로 인한 문제가 발생하기도 한다. 특히 해안지역은 그 지리적 특성으로 인해 해수침투에 노출되기 쉽고 해수침투에 노출된 지역의 지하수는 일반적인 경우보다 높은 염도를 가지는 경향이 있다. 만약 염도가 높은 지하수를 지속적으로 마시게 된다면 심장 및 신장질환 등 인체에 다방면으로 치명적인 영향을 끼치는 원인이 될 수 있기에 주의가 필요하다. 본 연구에서는 해수침투가 일어난 지역에서의 탈염을 위한 기술인 CDI(Capacitive Deionization)와 역삼투의 원리를 이용한 RO(Reverse Osmosis)의 적용가능성을 탐색해보고자 하며, 염수 농도에 따른 정수성능 실험을 진행하여 탈염성능을 평가해 보고자 한다. 또한 개발도상국의 일부 지역은 전력이 원활하게 보급되지 않는 경우가 많기에 본 연구에는 정수하는데 실제 사용하는데 필요한 소비전력을 계산하여 평가에 포함하고자 한다. 이를 통해 개발도상국 해수침투지역에 적합한 탈염기술을 제안할 수 있을 것으로 기대한다.

• 대한수의학회지
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• 제51권4호
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• pp.319-323
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• 2011

A 12-year-old spayed female Yorkshire terrier dog was presented with two-weeks history of lethargy, mental dullness and polydipsia. Neurologic examination revealed proprioceptive defect of all limbs and loss of swallowing gag reflex. The dog revealed persistent dehydration, hypernatremia, hyperosmolarity and hyposthenuria. On magnetic resornance imaging (MRI), the mass were heterogeneous signality on T1 weighted images, hyperintense signality on T2 weighted image with contrast enhancement on hypothalamohypophyseal lesion. Based on these findings, the dog was suspected as having pituitary gland tumor. Through water deprivation test and response to desmopressin acetate (1-deamino-8-D-arginine, DDAVP), this case was diagnosed by central diabetes insipidus (CDI). This paper reports the clinical sign, MRI, response to the exogenous antidiuretic hormone of CDI due to suspected pituitary tumor in a dog and DDAVP administration was evaluated effective therapy to correct hypernatremia induced by CDI.

• International Journal of Contents
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• 제10권2호
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• pp.42-46
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• 2014

This study suggests a teaching-learning method to improve creative design abilities of students majoring in design. By suggesting a creative design-inducing (CDI) teaching-learning method process and a creative design-inducing (CDI) teaching-learning method, this study aims to expand creative thinking among students with the aim of producing produce creative output as well as improving the effectiveness of design teaching. It also presents a case of the teaching-learning method in a design-related department, the process of teaching where the new method is applied is also examined. The teaching method this study suggests has the following merits: First, it allows the teacher to use various tools depending on the creative thinking abilities of individuals. By providing students with custom-made teaching, the method motivates and focuses students during the lesson. Second, it is easier for students to generate creative ideas than with other teaching methods.