• Title/Summary/Keyword: CD73

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GLOBAL CONVERGENCE OF AN EFFICIENT HYBRID CONJUGATE GRADIENT METHOD FOR UNCONSTRAINED OPTIMIZATION

  • Liu, Jinkui;Du, Xianglin
    • Bulletin of the Korean Mathematical Society
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    • v.50 no.1
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    • pp.73-81
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    • 2013
  • In this paper, an efficient hybrid nonlinear conjugate gradient method is proposed to solve general unconstrained optimization problems on the basis of CD method [2] and DY method [5], which possess the following property: the sufficient descent property holds without any line search. Under the Wolfe line search conditions, we proved the global convergence of the hybrid method for general nonconvex functions. The numerical results show that the hybrid method is especially efficient for the given test problems, and it can be widely used in scientific and engineering computation.

Drive Circuit Development for LED Tile Which is Added the Communication (통신기능이 부가된 LED Tile용 구동회로 개발)

  • Cheon, Woo-Young;Song, Sang-Bin;Kim, Jin-Hong;Kim, Gi-Hoon
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 2007.05a
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    • pp.70-73
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    • 2007
  • 생활수준의 향상으로 인하여 조명 및 디스플레이 제품을 이용하여 건물 및 건축물에 대하여 장식을 하는 것이 일반화 되어가고 있다. 본 연구에서는 옥외 및 옥내에 사인물로 사용되어지고 있으며 설치가 간편한 디스플레이 조명기기인 LED Tile을 개발하여 옥내 및 옥외용 디스플레이 조명 시장의 시장성 확보하기 위하여, 광학설계를 통한 고휘도 LED의 선정 및 배치, 케이스 설계를 실시하고 LED모듈에 AC 220V 전원을 직접 인가할 수 있으며 효율이 높고 최적화된 구동회로를 설계하였다. 또한 One Chip 마이크로컨트롤러를 사용하여 RGB LED의 광색가변 및 점멸 제어회로를 설계하고, LED 모듈간에 2개의 제어선만을 연결하여 다양하고 다이나믹한 패턴 동작(점멸, 광색가변)이 가능하도록 펌웨어를 설계하였다. 그 결과 설계된 LED Tile은 전체 크기가 $D130{\times}W130{\times}H50mm$로 매우 컴팩트하고 LED 배치 및 광학설계를 통하여 최대광도 60cd를 실현하였으며, LED Tile의 동작개수에 관계없이 설치가 간단하며 10개 이상의 디스플레이 패턴 제어가 가능하였다.

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A study on OLED device's accelerated lifetime test (OLED 소자의 가속수명 시험에 관한 연구)

  • Choi, Young-Tae;Joe, Jae-Rib
    • Journal of the Korea Safety Management & Science
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    • v.10 no.3
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    • pp.73-79
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    • 2008
  • Display's life time is defined as the time of 50% luminance drop. It was used luminance and temperature as accelerated factor to accelerated lifetime at test. When it's working jule-heat is generated and device's temperature is growing as any temperature because OLED is self-luminance display device. So we decided temperature condition is 25, $70^{\circ}C$, and luminance condition is $60{\sim}300cd/m^2$ in test. It's assumed accelerated lifetime model by result of the test.

A Novel Polymer Membrane for Extraction Applications

  • Wang, Xungai;Xu, Jianying;Paimin, Rohani;Shen, Wei
    • Fibers and Polymers
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    • v.3 no.2
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    • pp.68-73
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    • 2002
  • In this study, a new type of Aliquat 336/PVC membrane has been made for extraction experiments. This new membrane is capable of holding more Aliquat 336 than previously developed extraction membranes, hence overcoming a major problem that has confronted many researchers for a long time. The new membrane has been used try investigate the rate of extraction fur the Cd(II) ion in 2.0 M HCI solution and the effect of membrane thickness on the rate of extraction. The experimental results have shown this new membrane has a promising future in relevant industrial applications. A new method is also used in this study to qualitatively identify the oily substance on the surface of membrane after the extraction experiment was completed. This oily substance has been found to be Aliquat 336.

Radioimmunotherapy (I): Development of Radioimmunoconjugates (방사면역치료(I): 방사면역접합체 개발)

  • Choi, Tae-Hyun;Lim, Sang-Moo
    • Nuclear Medicine and Molecular Imaging
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    • v.40 no.2
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    • pp.66-73
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    • 2006
  • Monoclonal antibodies are designed to bind specifically to certain antigen, give therapeutic effect to the target and to be produced in large scale with homogeneity. The monoclonal antibodies conjugated with radionuclide can deliver therapeutic irradiation to the target, and showed successful results in certain malignancies, which is known as radioimmunotherapy. The target-to-background ratio depends on the antigen expression in the target and normal tissues, which is related to the therapeutic efficacy and toxicity in radioimmunotherapy. For the solid tumor beta-ray energy should be high, but lower beta energy is better for the hematological malignancies. I-l31 is widely used in thyroid cancer with low cost and high availability. Labeling monoclonal antibody with I-131 is relatively simple and reproducible. Some preclinical data for the I-131 labeled monoclonal antibodies including acute toxicity and efficacy are available from already published literatures in KIRAMS, physician sponsored clinical trial protocols using Rituximab, KFDA approved anti-CD20 chimeric monoclonal antibody and I-131 were approved by KFDA and currently are ongoing.

Analysis for the secondary gamma-ray emission for glasses irradiated with various doses of fast neutron: Case study borate and silicate glasses

  • O.L. Tashlykov;V. Yu. Litovchenko;N.M. Aristov;K.A. Mahmoud
    • Nuclear Engineering and Technology
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    • v.55 no.7
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    • pp.2366-2372
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    • 2023
  • Are borate and silicate glasses suitable for working as shieling materials against fast neutrons? To correctly answer the above question, some silicate, and borate-based glasses were fabricated and irradiated with various doses of fast neutrons varied between 1.73 and 12.10 MGy. The color and hardness of the fabricated glasses were affected by the fast neutron fluence where the transparent glasses turned colored as well as the hardness of the fabricated glasses was decreased. The gamma-ray spectrometric analysis shows a high activity concentration produced in the barium borate glasses due to the formation of radioisotopes Ba-131 and Ba-133 reaches to 5.92E+05 Bq and 4.25E+03 Bq, respectively for sample Cd-5 Batch 3. Additionally, the gamma-ray spectrometric analysis for the sodium silicate glasses shows low activity concentrations emitted from isotopes formed due to the activation of Y2O3-associated impurities. These activities are low compared to that emitted by barium borate-based glasses.

Adsorption of Heavy Metal Ions onto Chemically Oxidized Ceiba pentandra (L.) Gaertn. (Kapok) Fibers

  • Chung, Byung-Yeoup;Cho, Jae-Young;Lee, Min-Hee;Wi, Seung-Gon;Kim, Jin-Hong;Kim, Jae-Sung;Kang, Phil-Hyun;Nho, Young-Chang
    • Journal of Applied Biological Chemistry
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    • v.51 no.1
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    • pp.28-35
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    • 2008
  • The physico-chemical properties of kapok fibers were altered via the combination processes of chlorite-periodate oxidation, in order to assess their efficacy as a heavy metal adsorbent. The chemically-oxidized kapok fibers were found to harbor a certain amount of polysaccharides, together with lowered lignin content. This alteration in lignin characteristics was clearly confirmed via FTIR and NBO yield. Moreover, chemically oxidized kapok fibers retained their hollow tube shape, although some changes were noted. The chemically oxidized kapok fibers evidenced elevated ability to adsorb heavy metal ions with the best fit for the Langmuir adsorption isotherm model. Three cycles of adsorption-desorption were conducted with in-between regeneration steps. Our experimental results indicated that chemically oxidized kapok fibers possessed excellent adsorption characteristics, and the modified kapok fibers could be completely regenerated with almost equimolar diluted sodium hydroxide. Pb, Cu, Cd and Zn ions evidenced adsorption rates of 93.55%, 91.83%, 89.75%, and 92.85% on the chemically oxidized kapok fibers. The regeneration efficiency showed 73.58% of Pb, 71.55% of Cu, 66.87% of Cd, and 75.00% of Zn for 3rd cycle with 0.0125N NaOH.

Effect of Coarse mateflal on the mechanical properties of Soil (조립재가 흙의 역학적 성질에 미치는 영향)

  • 윤충섭;김호일
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.31 no.3
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    • pp.57-69
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    • 1989
  • The study was carried out for the strength parameter of coarse grained Soil and slope stability analysis of earth dam. The test samples were taken fifteen kinds of soil from cohesive soil to coarse gravel. The degree of compaction of test samples for shear test and permeability test was chosen 95 percentage of maximum dry density. The results of this study are as follows ; 1.The maximum dry density(Yd) of coarse grained soil increase in proportion to coarse particles(P) with the relation of Y d= 1.609+0.0043P. 2.The coefficients of permeability(k) decrease by the increase of fine particles(n) with the relation of k=0.0426e-0 185n. 3.The cohesions of soil decrease by the increase of coarse particles, but internal friction angles are more increased in same condition. 4.The internal friction angles(${\Phi}$) decrease in inverse proportion to void ratio(e) with the relation of ${\Phi}$ = 73.068 - 69.268e. 5.The strength parameters( Ct ${\Phi}$t) by triaxial compression test are clearly smaller than that (Cd, ${\Phi}$d) by direct shear test in fine grained soil, but the differences between both parameters are a little in coarse grained soil.The relations of both parameters are as follows; Ct = O.544Cd + 0.04 ${\Phi}$t= 1.282${\Phi}$d-2306 6.In cohesive soil, the strength parameters( Cl ${\Phi}$l) by large size shear test apparatus are similar to the strength parameters(Cs , ${\Phi}$s) by small size shear test appratus, but Cs and ${\Phi}$s values are larger than Cl and ${\Phi}$l values from 10 percentage to 20 percentage in coarse grained soil. 7.The fine grained soil is inappropriate to high dam more than 20 meters and it must be taken coarse grained soil with high internal friction angle for high dam.

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Concentration and Distribution of Heavy Metals in Sediments and Bivalves(Solen Strictus Gould) from Tidal Flats along the Mid-Western Coast, Korea (서해 중부연안 갯벌에서의 저질 및 패류 (Solen Strictus Gould) 중 중금속 분포특성)

  • 황갑수;신형선;김강주;여성구;김진삼
    • Journal of Environmental Health Sciences
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    • v.27 no.4
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    • pp.25-34
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    • 2001
  • Heavy metal level and distribution in sediment and bivalves from the tidal flats along the mid-western coast, Korea. were investigated in this study. The averages of heavy metal concentrations in sediments from 5 sampling sites ranged from 86.35-187.77mg/kg for Mn. 13.25-17.73mg/kg for Zn.6.80-11.85mg/kg for Cr,4.28-6.25mg/kg for Ni, 1.85-3.09mg/kg for Cu, 0.004-0.02()mg/kg for Cd and 5.70-10.41 mg/kg for Pb, respectively. From the results of heavy metal concentrations in mussels, the levels of Mn and Fe concentrations in S. strictus collected from S1 antral S2 sites were particularly high. Deviations of heavy metal concentrations am(Ing the individual mussels from the same site could be largely minimized by selecting mussel samples of the limited range in body size(8.5-11cm). Among the mussels of the limited body size, heavy metal concentrations both in the flesh and in the whole soft part were not strongly related to the body size. It was shown that ,in S. strictus, Cu moves fast into the flesh parts after absorption, while Pb and Fe move fast into the non-flesh parts. Overally. the heavy metal concentration in the tends to increase with that in the whole soft parts. The concentration factors(heavy metal concentration in 5. strictus/heavy metal concentration in sediment) showed that, of the examined meta1s. Cd is the most cumulative in the body of S. strictus followed by Zn and Cu, while Mn, Cr. Ni and Pb are not cumulative.

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First Outcome of MDR-TB among Co-Infected HIV/TB Patients from South-West Iran

  • Motamedifar, Mohammad;Ebrahim-Saraie, Hadi Sedigh;Abadi, Ali Reza Hassan;Moghadam, Mahboube Nakhzari
    • Tuberculosis and Respiratory Diseases
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    • v.78 no.3
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    • pp.253-257
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    • 2015
  • Background: Tuberculosis (TB) is the leading cause of mortality among human immunodeficiency virus (HIV) patients and the majority of them occur in developing countries. The aims of the present study were to determine the frequency of HIV/TB co-infection and other probable associated factors. Methods: This 10 year retrospective study was conducted on 824 HIV patients in the south-west of Iran. HIV infection was diagnosed by the enzyme linked immunosorbent assay and confirmed by Western blot. TB diagnosis was based on consistency of the clinical manifestations, chest X-ray, and microscopic examination. Drug susceptibility testing was done by the proportional method on $L{\ddot{o}}wenstein$-Jensen media. Results: Of 824 HIV patients, 59 (7.2%) were identified as TB co-infected and the majority (86.4%) of them were male. Of the overall TB infected patients, 6 cases (10.2%) showed multidrug-resistant with the mean CD4+ lymphocyte count of $163{\pm}166cells/mm^3$. The main clinical forms of TB were pulmonary (73%). There was a significant (p<0.05) correlation between TB infection and CD4+ lymphocyte counts ${\leq}200cells/mm^3$, gender, prison history, addiction history, and highly active anti-retroviral therapy. Conclusion: We reported novel information on frequency of HIV/TB co-infection and multidrug resistant-TB outcome among co-infected patients that could facilitate better management of such infections on a global scale.