• Title/Summary/Keyword: CD7

Search Result 2,343, Processing Time 0.024 seconds

The Effects of Herbal-acupuncture with Aconiti Iateralis Preparata Radix solutionon Collagen-induced arthritis (부자약침(附子藥鍼)이 흰쥐의 Collagen 유발 관절염에 미치는 영향)

  • Kim, Yoon-Hee;Yim, Yun-Kyoung;Lee, Hyun
    • Korean Journal of Acupuncture
    • /
    • v.23 no.2
    • /
    • pp.137-154
    • /
    • 2006
  • Results: 1. In the AlPR-HA group, the incidence of arthritis and arthritis index were significantly decreased. 2. In the AlPR-HA group, the levels of $IL-6,\;IFN-{\gamma},\;TNF-{\alpha},\;IL-1{\beta},\;IgG,\;IgM,\;Anti-collagen\;II$ in serum of the CIA mouse were significantly decreased. 3. In the AlPR-HA group, the levels of $IFN-{\gamma:,\;IFN-{\gamma}\;/IL-4$ in spleen cell culture of the CIA mouse were significantly decreased. 4. In the Hematoxylin and eosin stain, the cartilage destruction and synovial cell proliferation were decreased in the AIPR-HA group. 5. In the Masson's trichrome stain, the collagen fiber expressions were similar with that of the Normal group. 6. In the AlPR-HA group, the expression ratio of $CD3e^+$ to $CD19^+$ cell and $CD4^+$ to $CD8^+$ cell were similarly maintained as Normal group in the CIA mouse lymph nodes. 7. In the AlPR-HA group, $CD3e^+/CD69^+$ cells in the CIA mouse joint and $CD11a^+/CD19^+$ cells and $CD11b^+/Gr-1^+$ cells in the CIA mouse lymph nodes were significantly decreased. 8. In the AIPR-HA group, $CD4^+/CD25^+$ cells were significantly decreased in the CIA mouse spleen cell and were similarly maintained as Normal group in the CIA mouse lymph nodes. Conclusions: These results suggest that AlPR-HA at 51'36 has an effect to control synovial cell proliferation and cartilage destruction in rheumatoid arthritis.

  • PDF

Biological Functions of Lactoferrin and Antigenic Determinants of Lactoferricin (Lactoferrin의 생리적 기능과 Lactoferricin의 항원결정기)

  • Nam, Myeong-Su;Shimazaki, K.
    • Journal of Dairy Science and Biotechnology
    • /
    • v.14 no.2
    • /
    • pp.229-245
    • /
    • 1996
  • 1. CM-Sephadex C-50-120 column을 사용하여 HLF를 효과적으로 정제하였다. CM-Sepha-dex 50-120 column chromatography를 수행한 결과, HLF는 NaCl 350 mM-500 mM 사이에서 용출되었으며, 용출된 분획을 SDS-PAGE를 수행해서 단일 band를 확인하였다. Anti-HLF antibody를 이용한 Western blotting 결과 nitrocellulose paper 상에 단일 band 가 나타나므로 HLF 가 효과적으로 정제되었다는 것을 알 수 있었다. 2. Con A, PWM, PWA LPS 등의 자극원으로 단핵구와 대식세포를 자극한 다음 BLF를처리한 배 양액을 IL-1 bioassy한 결과는 Con A 33%, PMA 33%, PWM 15%, LPS 35% 이고, HLF로 처리하여 IL-1 bioassay를 한 결과는 Con A 15%, PMA 22%, PWM 10%, LPS 5%로 감소된 것으로 나타났다. 3. K-562 세포를 이용한 colony forming assay에서 BLF가 10 g/ml일 때는 30%, 30 g/ml일 때는 35%, HLF는 10 g/ml일 때는 5%,30 g/ml일 때는 30%의 저해를 나타냈다. 4. Lactoferrin의 면역증강효과를 알아보기 위하여 hapten인 VCR-BSA를 투여 한 후, 생성되는 항체생성능력을 ELISA로 비교하였다. 그 결과 HLF 및 BLF 투여군에서 대조군에 비하여 adjuvant 효과를 관찰할 수 있었다. 또한 이때 macrophage 수는 대조군에 비하여 HLF와 BLF를 투여한 군이 증가됨을 알 수 있었다. 이러한 결과로 미루어 볼 때 LF는 macrophage를 활성화 시켜서 항체 생성 능력을 증가시키는 효과가 있음을 관찰할 수 있었다. 5. Balb/c mouse의 thymus로부터 분리한 CD4- CD8- 세포를 BLF로 처리하여 24 시간 배양한 후 CB4$^-$ CD8$^-$ 세포의 분화를 측정한 결과, CD4$^-$를 CD4$^+$ 로 분화하였다. 그리고 HLF로 처리하여 24 시간 배양 후 CD4$^-$ CD8$^-$ 세포의 분화를 측정한 결과, CD4$^-$ CD8$^-$를 CD4$^+$ CD8$^+$ 로 분화하였다. 6. Lactoferrin이 T cell의 IL-2 production에 미치는 영향은 PMA 처리군, PMA+OKT3처리군, LF 단독 처리군 보다 PMA+OKT3+LF를 처리한 군이 IL-2 생성에 영향을 미쳤다. 7. Lfcin B의 단일크론항체에 의해 인식되어지는 Lfcin B의 항원결정기는 ‘QWR’로 밝혀졌다.

  • PDF

Heat-treatment Effects of CdS Thin Films Fabricated by Thermal Evaporation Method (진공증착법으로 제작한 CdS 박막의 열처리효과)

  • Park, Tae-Seong;Jin, Gyo-Won;Kim, Yeong-Ho;Han, Eun-Ju;Kim, Geun-Muk
    • Korean Journal of Materials Research
    • /
    • v.7 no.11
    • /
    • pp.981-985
    • /
    • 1997
  • 열증착법에 의해서 온도 85$^{\circ}C$인 glass기판 위에 CdS 박막을 제작하였다. 두께가 200nm정도로 측정된 CdS박막은 공기 중에서 온도 25$0^{\circ}C$-55$0^{\circ}C$범위에서 각각 30분간 열처리 되었으며 이들 시료에 대하여 4-point probe, XRD, SEM, UV-Spectrophotometer 및 광발광 측정으로 전기적 광학적 특성을 조사하였다. 이들의 일련의 실험값은 열처리 온도 37$0^{\circ}C$ 근처에서 구조의 변화를 보여주었는데, 열처리 온도에 대한 비저항아니 XRD, SEM 의 측정은 cubic로부터 hexagonal구조로의 변환을 나타내었다. 특히 상온에서 측정한 광발광에서 green edge emission(GEE)피이크가 2.42eV를 나타내었는데 이 때의 발광 중심은 열처리할 때 생긴 S-vacancy에 보상된 산소로 이루어진 'CdO'의 악셉터준위에 기인하는 것으로 해석되며 그 이온화 에너지는 약 0.16eV이었다.

  • PDF

Cadmium - Titanium alloy plating (Cadmium - Titanium 합금도금 공정개발)

  • 이종호;박용성
    • Proceedings of the Korean Society of Propulsion Engineers Conference
    • /
    • 1994.04a
    • /
    • pp.10-15
    • /
    • 1994
  • 전기도금 공정에서 발생하는 수소취성은 다량의 수소이온이 강제품에 흡수되어 취화되는 현상을 나타내는 것으로 인장강도 200KSI 이상이 요구되는 항공기용 또는 로켓트 추진기관용 초고강도강에서 크게 문제가 되고 있다. 본 내용은 전기 카드뮴도금 작업시에 발생되는 수소취성에 대하여 간략하게 기술하고. 이 수소취성을 제거하는 방법 및 수소취성을 저게 생성시키는 저취성도금인 Cd-Ti 합금도금의 공정개발 결과를 보고한다. 실험결과에 의하면 도금층의 Ti함량은 0.1-0.7%이며 Ti의 공석에 의하여 Cd 도금에 비하여 저취성을 나타냈으며, Cd-Ti합도금의 내식성은 상대평가인 염수분무시험 결과 Cd도금과 비교하여 소재표면의 부식을 일으키는 붉은녹발생까지의 시간이 500시간으로 보다 높은 내식성을 나타내었다. 그리고 Cd-Ti 합금의 공정표준 및 Ti농도의 관리방법 등을 정리하여 보고한다.

  • PDF

Measurement on the deep levels of $Cd_4GeSe_6$ single crystals ($Cd_4GeSe_6$ 단결정의 deep level측정)

  • 김덕태
    • Electrical & Electronic Materials
    • /
    • v.7 no.6
    • /
    • pp.504-510
    • /
    • 1994
  • In this work the crystal structure, optical absorption and photoluminescence of Cd$_{4}$GeSe$_{6}$ single srystals grown by the vertical bridgman method are investigated. From the observed results of the PICTS, we proposed on energy band model which contains deep levels between the conduction band and the valence band. The energy band model permit us to explain the mechanism of the radiative recombination for the Cd$_{4}$GeSe$_{6}$ single crystals.als.

  • PDF

Optimal Position of the Dampers in a CD-ROM Drive to Remove the Tilting Vibration mode (기울어짐 진동 모드 제거를 위한 CD-ROM 드라이브의 댐퍼 최적 위치)

  • 정진태;박준민;노대성
    • Journal of KSNVE
    • /
    • v.7 no.3
    • /
    • pp.393-399
    • /
    • 1997
  • This study proposes a methodology with which the optimal damper positions of the feeding system in a CD-ROM drive are determined to removal the harmful tilting vibration modes. For this purpose, vibration characteristics of the feeding system are identified by a theoretical modeling as well as vibration experiments. We perform the modal testings using the impact hammer and shaker; furthermore, we establish a vibration model due to the rigid-body motion. The analysis and experiments show that the feeding system has three rigid-body vibration modes in the low-frequency region and two of them come from the tilting modes. We show that the tilting modes can be removed by determining the damper positions.

  • PDF

Luminescent Characteristics of CdSe Quantum Dot Phosphor Depending on Se Precursor Ratio (Se 전구체 함량 따른 CdSe 양자점 형광체의 발광특성)

  • Eom, Nu Si A;Kim, Taek-Soo;Choa, Yong-Ho;Kim, Bum Sung
    • Journal of Powder Materials
    • /
    • v.19 no.6
    • /
    • pp.442-445
    • /
    • 2012
  • The quantum dots (QD) have unique electrical and optical properties due to quantum dot confinement effect. The optical properties of QDs are decided by various synthesis conditions. In a prior QDs study, a study on the QDs size with synthesis condition such as synthesis time and temperature is being extensively researched. However, the research on QDs size with composition ratio has hitherto received scant attention. In order to evaluate the ratio dependence of CdSe crystal, synthesis ratio of Se precursor is changed from 16.7 mol%Se to 44 mol%Se. As the increasing Se ratio, the band gap was increased. This is caused by red shift of emission. We confirmed optical property of CdSe QDs with composition ratio.

A Properties of n-CdS/p-InP Heterojunction Diodes (n-CdS/P-InP 이종접합 다이오드 특성)

  • 송복식;문동찬;김선태
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 1993.11a
    • /
    • pp.60-63
    • /
    • 1993
  • We have prepared n-CdS/p-InP hetero- junction solar cells by thermal evaporation. The efficiency under the optium conditions without the grid line contact was 7.3%, and the solar cell having glid line contact with SiO AR coating was the open circuit voltage of 0.71V, the short circuit voltage current density of 15mA/cm$^2$, the fill factor of 0.73, and the efficiency of 11.5%. As result of photoresponse in 400-1000nm wavelength the cutoff of n-CdS/p-InP solar at 500nm results from absorption by the CdS \"window\" and the cutoff at 930 nm result from absorption by the InP.

  • PDF

Photoluminescent properties for CdTe crystal grown by Bridgman method (Bridgman 방법으로 성장된 CdTe의 광발광 특성)

  • Hong, Kwang-Joon;You, Sang-Ha
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2004.04b
    • /
    • pp.42-45
    • /
    • 2004
  • High quality CdTe single crystal for the solar cell fabrication was grown by vertical Bridgman method. The etch pits patterns of {111}surfaces of CdTe etched by Nakagawa solution was observed the {111} A composed of Cd atoms with typical triangle etch pits of pyramid mode. From the photoluminescence measurement on {111}A, we observed free exciton($E_x$) existing only higy quality crystal and neytral acceptor bound exciton($A^0$,X) having very strong peak intensity. Then, the full width at half maximum and binding energy of neutral acceptor bound exciton were 7 meV and 5.9 meV, respectively. By Haynes rule, an actibation energy of impurity was 59 meV. Therefore, the origins on impurity level acting as a neutral acceptor were associated Ag or Cu elements.

  • PDF

Adsorption Characteristics of Cu, Zn and Cd by Granular Activated Carbon (입상활성탄에 의한 Cu, Zn, Cd 이온의 흡착 특성)

  • 옥삼복;정용준;정승원;강운석
    • Journal of Environmental Science International
    • /
    • v.11 no.4
    • /
    • pp.333-338
    • /
    • 2002
  • In this work, the characterization of adsorption of Cu, Zn and Cd on granular activated carbon in water has been studied. The factors that affect adsorption in boundary between activated carbon and wastewater are concentration, temperature, contact time, pH and so on. As the result of this study, the maximum adsorption amount of Cu occurred near pH 7, while that of Zn and Cd was near pH 9.6 and 10, respectively. As contact time and temperature are transformed, such factors as optimum contact time and temperature are taken into consideration in an adsorptive process of heavy metal because an adsorption and a reducing process occur. In isotherm of Freundlich, 1/n values of Cu, Cd capacity were between 0.16 and 0.5.