• 제목/요약/키워드: CD59

검색결과 245건 처리시간 0.024초

Arsenazo I-XAD-16 킬레이트 수지를 이용한 Th(IV)과 U(VI)의 분리 (Separation of Th(IV) and U(VI) Using Arsenazo I-XAD-16 Chelating Resin)

  • 서정민;김민균;임재희;이창헌;이원
    • 분석과학
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    • 제8권3호
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    • pp.397-404
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    • 1995
  • Three Arsenazo I-XAD Chelating resins, with different surface areas and pore sizes were synthesized and characterized. The total sorption capacities of these chelating resins for Cu(II) at pH 5.0 by batch method decreased as follows, Arsenazo I-XAD-16(0.59mmol/g)>Arsenazo I-XAD-4(0.56mmol/g)>Arsenazo I-XAD-2(0.38mmol/g). The sorption and desorption properties of Arsenazo I-XAD-16 chelating resins for U(VI), Th(IV), Hf(IV), Zr(IV), Ni(II), Mn(II), Cd(II). and Cu(II) were studied by both batch and elution method. The Arsenazo I-XAD-16 chelating resin was successfully applied to the separation and concentration of trace U(VI) and Th(IV) in sea and waste waters.

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광통신 모듈용 분포 귀환형 InGaAsP/InP 레이저 다이오드 제작 및 소자 특성평가 (Fabrication process and device characterization of distributed feedback InGaAsP/InP laser diodes for optical fiber communication module)

  • 전경남;김근주
    • 반도체디스플레이기술학회지
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    • 제10권4호
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    • pp.131-138
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    • 2011
  • We fabricated distributed feedback InGaAsP/InP laser diodes for optical fiber communication module and characterized the lasing properties in continuous wave operation. The active layer of 7-period InGaAsP(1.127 eV)/InGaAsP(0.954 eV) multi-quantum well structure was grown by the metal-organic chemical vapor deposition. The grating for waveguide was also fabricated by the implementation of the Mach-Zehender holographic method of two laser beams interference of He- Cd laser and the fabricated laser diode has the dimension of the laser length of $400{\mu}m$ and the ridge width of $1.2{\mu}m$. The laser diode shows the threshold current of 3.59 mA, the threshold voltage of 1.059 V. For the room-temperature operation with the current of 13.54 mA and the voltage of 1.12 V, the peak wavelength is about 1309.70 nm and optical power is 13.254 mW.

Characterization of a metalloprotease from an isolate Bacillus thuringiensis 29-126 in animal feces collected from a zoological garden in Japan

  • Lee, Eun Seok;Lee, Hyun Woo;Lee, Dong-Hyun;Kim, Hoon
    • Journal of Applied Biological Chemistry
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    • 제59권4호
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    • pp.373-377
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    • 2016
  • An extracellular metalloprotease, Btmp, was partially purified from the culture supernatant of Bacillus thuringiensis 29-126, isolated from animal feces collected in a zoological garden in Japan, by ultrafiltration, ammonium sulfate precipitation, and a set of chromatography on Sephadex G-75 and High-Q. The molecular mass of the protease was estimated to be 60 kDa by SDS-PAGE. The enzyme showed optimum activity at $50^{\circ}C$ and pH 6.0, and had a half-life of 14 min at $50^{\circ}C$. The enzyme activity was not influenced by $Na^+$, $K^+$, $As^+$, $Mg^{+2}$, $Ca^{2+}$, $Ba^{2+}$, and phenylmethylsulfonyl fluoride, but it was moderately inhibited by $Zn^{+2}$ at a concentration of 1.0 mM, while the activity was significantly inhibited to less than 50 % by $Cu^{2+}$, $Co^{2+}$, $Cd^{2+}$, and ethylenediaminetetraacetic acid. Interestingly, the enzyme was activated to 178 % by 1.0 mM of $Mn^{2+}$. From these results, it may be suggested that the protease is a novel extracellular manganeseactivated metalloprotease.

Assessment of Solubility, Heavy Metals and Microbial Safety in Differently- Treated Muscle Tissues of Mackerel Scomber japonicus

  • Asaduzzaman, A.K.M.;Lee, Won-Kyoung;Chun, Byung-Soo
    • Fisheries and Aquatic Sciences
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    • 제17권1호
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    • pp.59-65
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    • 2014
  • We measured the reductions in size and solubility of mackerel muscle that was freeze-dried, deoiled by supercritical carbon dioxide (SC-$CO_2$), or roasted. The percent size reduction and solubility were high in SC-$CO_2$-treated muscle compared with freeze-dried and roasted muscle. We used oil-free residues to test for heavy metals and determine microbial safety. The SC-$CO_2$, hexane, and ethanol were used to separate oil from muscle. The concentrations of cadmium (Cd) in all treated muscles were less than the values reported in the literature, as were the concentrations of lead in SC-$CO_2$- and hexane- treated muscle. In contrast, concentrations of arsenic and mercury in muscles were greater than the reported values regardless of treatment. Zinc and iron, which are beneficial for health, were found in high levels after all treatments of muscle tissue. After 6 months of storage at different temperatures, SC-$CO_2$-and ethanol-treated muscle showed few bacterial colonies, and none were found after 4 months of storage at $-20^{\circ}C$. These results will be useful to food-processing industries for maintaining high-quality, safe mackerel muscle.

하이퍼텍스트 한글백과사전의 개발 (Development of Hypertext Encyclopedia)

  • 전경헌;강현규;김용일;박상규;최기선
    • 한국정보과학회 언어공학연구회:학술대회논문집(한글 및 한국어 정보처리)
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    • 한국정보과학회언어공학연구회 1993년도 제5회 한글 및 한국어정보처리 학술대회
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    • pp.59-70
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    • 1993
  • 개인용 컴퓨터가 많이 보급되고, CD-ROM과 같은 대용량의 기록장치가, 널리 퍼지면서, 전자화된 사전이 널리 사용되게 되었다. 그러나 이러한 전자사전들은 대개 매우 단순화된 탐색기능만을 제공하므로, 전자화의 잇점을 크게 살리지 못하고 있다. 따라서, 컴퓨터의 힘을 빌린, 보통의 종이로된 사전보다 훨씬 유용한 전자사전을 생각해 볼 수 있을 것이다. 이러한 노력이 과거 80년대 말에 하이퍼텍스트로 시작되어 이제는 매우 상업적인 곳에까지 사용되어지고있다. 국내에서도 전자사전의 개발은 다양하게 진행되어오고 있으나, 대부분 컴퓨터를 위한 사전, 다시 말하면, 빠른 접근시간, 적은 메모리사용만을 고려한 사전에 그치고 있다. 본 논문에서는 이러한 필요성에 부합하여, 백과사전자료를 가지고 사람을 위한 전자백과사전을 개발하는 방법을 소개한다. 특히, 이러한 개발과정을 자동화 할 수 있음을 보이고, 백과사전을 하이퍼텍스트로 자동변환하는 방법을 자세히 기술한다. 이 방법은 원시 자료를 하이퍼텍스트로 변환하기 좋은 정형화된 중간자료로 바꾸고, 이 중간자료와 기초적인 명사추출 알고리즘을 이용하여, 각 노드들 사이에 링크를 만드는 것이다. 또한, 이 방법을 이용하여 개발한 HE(Hypertext Encyclopedia) 시스템을 소개한다.

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누에번데기 및 누에애벌레 밀리타리스동충하초(Cordyceps militaris) 열수추출물의 투여가 고형암이 유발된 마우스의 종양성장 억제 및 면역기능에 미치는 영향 (Tumor Growth Inhibitory and Immunomodulatory Activities of Cordyceps Militaris Water Extracts in ICR Mice Bearing Sarcoma-180 Solid Tumor)

  • 이해미;이여진;박태선
    • 한국식품영양과학회지
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    • 제33권1호
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    • pp.59-65
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    • 2004
  • 본 연구에서는 누에번데기 또는 누에애벌레를 기주로 하여 인공 재배된 밀리타리스동충하초의 고형암 성장억제 및 면역조절 기능을 평가하였다. 이를 위해 sarcoma-180 세포주를 겨드랑이에 피하 이식받은 ICR 마우스를 대상으로 밀리타리스동충하초 또는 유효성 분으로 알려진 cordycepin을 10일간 복강투여한 후 고형암 성 장저지능, 면역관련 장기의 무게변화, 비장 내 면역세포수의 변화, 그리고 비장세포에 의한 interleukin-2(IL-2) 생성능을 측정하여 다음과 같은 결론을 얻었다. 겨드랑이에 고형암을 이식받은 마우스에게 50 mg/kg(CMP50) 또는 100 mg/kg(CMP100)의 누에번데기 밀리타리스동충하초 추출물을 10일간 투여한 결과 생리식염수를 투여한 대조군에 비해 3주 후 고형암 성장이 47.3% 및 57.6% 유의하게 억제되었다(p<0.05). 50 mg/kg(CML50) 및 100 mg/kg(CML100)의 누에애벌레 밀리타리스동충하초를 투여받은 경우 35.5% 및 37.1%, 그리고 1 mg/kg 및 2 mg/kg의 cordycepin을 투여받은 군의 경우 26.1%와 29.8%의 고형암 성장 억제효과가 관찰되었다(p<0.05). 고형암을 이식받은 후 누에번데기 또는 누에애벌레 밀리타리스동충하초를 투여받은 마우스는 대조군에 비해 흉선무게가 38∼44% 유의하게 증가하였고(p<0.05), 비장내 CD4+ 및 CD8+ T-세포수, NK-세포수(63∼110% 증가), 그리고 비장세포에 의한 IL-2 생성능(33∼51%증가)이 모두 유의하게 증가하였다(p<0.05). 이상의 결과를 종합해 볼 때, 밀리타리스동충하초 열수추출물은 고형암의 성장을 억제하는 효과가 있으며, 이와 같은 밀리타리스동충하초 추출물의 항암활성은 면역기능 증강효과와 연관이 있을 것으로 생각된다. 아울러 밀리타리스동충하초의 고형암 성장억제 및 면역조절 기능은 cordycepin 단일물질에 비해 더 우수하였다.

용접사업장 근로자의 흄 및 금속 노출농도에 대한 평가와 혈중 금속 농도 (Airborne Concentrations of Welding Fume and Metals of Workers Exposed to Welding Fume)

  • 최호춘;김강윤;안선희;박화미;김소진;이영자;정규철
    • 한국산업보건학회지
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    • 제9권1호
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    • pp.56-72
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    • 1999
  • Airborne concentrations of welding fumes in which 13 different metals such as Al, Cd, Cr, Cu, Fe, Mn, Mo, Ni, Pb, Si, Sn, Ti, and Zn were analyzed were measured at 18 factories including automobile assembly and manufactures, steel heavy industries and shipyards. Air samples were collected by personal sampler at each worker's worksite(n=339). Blood levels of Cd, Cu, Fe, Mn, Pb and Zn were also measured from samples taken from 447 welders by atomic absorption spectrometry and compared with control values obtained from 127 non-exposed workers. The results were as follows ; 1. Among various welding types, $CO_2$ welding 70.2 % were widely used, shielded metal arc welding(SMAW) 22.1 % came next, and rest of them were metal inert gas(MIG) welding, submerged arc welding(SAW), spot welding(SPOT) and tungsten inert gas(TIG) welding. 2. Welding fume concentration was $0.92mg/m^3$($0.02{\sim}15.33mg/m^3$) at automobile assembly and manufactures, $4.10mg/m^3$($0.02{\sim}70.75mg/m^3$) at steel heavy industries and $5.59mg/m^3$($0.30{\sim}91.16mg/m^3$) at shipyards, respectively, showing significant difference among industry types. Workers exposed to high concentration of welding fumes above Korean Permissible Exposure Limit(KPEL) amounted to 7.9 % and 12.5 %, in $CO_2$ welding and in SMAW at automobile assembly and manufactures and 62.7 % in $CO_2$ welding, and 12.5 % in SMAW at shipyards, and 66.2 % in $CO_2$ welding and 70.6 % in SMAW at steel heavy industries. 3. Geometric mean of airborne concentration of each metal released from welding fumes was below one 10th of KPEL in all welding types. Percentage of workers, however, exposed to airborne concentration of metals above KPEL amounted to 16.8 % in Mn and 7.6 % in Fe in $CO_2$ welding; 37.5 % in Cu in SAW, 30 % in Cu in TIG; and 25 % in Pb in SPOT welding. As a whole, 76 Workers(22.4%) were exposed to high concentration of any of the metals above KPEL. 4. There were differences in airborne concentration of metals such as Al, Cd, Cr, Cu. Fe. Mn, Mo, Ni, Pb, Si, Sn, Ti and Zn by industry types. These concentrations were higher in shipyards and steel heavy industries than in automobile assembly and manufactures. Workers exposed to higher concentration of Pb above KPEI amounted to 7.4 % of workers(7/94) in automobile assembly and manufactures. In shipyards, 19.2 % of workers(19/99) were over-exposed to Mn and 7.1 % (7/99) to Fe above KPEL. In steel heavy industries, 14.4 %(21/146), 7.5 %(11/146) and 13 %(19/146) were over-exposed to Mn, Fe and Cu, respectively. As a whole, 76 out of 339 workers(22.4%) were exposed to any of the metals above KPEL. 5. Blood levels of Cd, Cu, Fe, Mn, Pb, and Zn in welders were $0.11{\mu}g/100m{\ell}$, $0.84{\mu}g/m{\ell}$, $424.4{\mu}g/m{\ell}$, $1.26{\mu}g/100m{\ell}$, $5.01{\mu}g/100m{\ell}$ and $5.68{\mu}g/m{\ell}$, respectively, in contrast to $0.09{\mu}g/100m{\ell}$, $0.70{\mu}g/m{\ell}$, $477.2{\mu}g/m{\ell}$, $0.73{\mu}g/100m{\ell}$, $3.14{\mu}g/100m{\ell}$ and $6.15{\mu}g/m{\ell}$ in non-exposed control groups, showing significantly higher values in welders but Fe and Zn.

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이성간 성접촉을 통한 HIV 전파율과 위험인자에 관한 연구: 남성으로부터 여성으로의 전파 (Male to Female Heterosexual Transmission of HIV in Korea: Transmission Rate and Risk Factors)

  • 고운영;기미경;최병선;강춘;도경미;이주현;이주실
    • Journal of Preventive Medicine and Public Health
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    • 제32권2호
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    • pp.228-235
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    • 1999
  • Objectives: Despite the importance of human immunodeficiency virus(HIV) transmission through heterosexual contact, the features of heterosexual transmission has not been well studied in Korea. So we conducted a cross sectional study to determine the transmission rates in married couples and assess risk factors for male to female heterosexual transmission of HIV. Methods: 169 HIV-infected males and their female sex partners were recruited from 1985 to tune 1998. We examined female sex partner's HIV infection status and interviewed male index partners and their female sex partners about demographic characteristics and sexual practices. We analysed heterosexual transmission rate by epidemiologic characteristics, disease status and sexual practices. And we assessed risk factors for HIV infection by univariate and multivariate analysis. Results: 30 female sex partners were infected at enrollment, yielding an transmission rate of 17.8%. Among couples who had used condoms consistently, none of the female sex partners was infected with HIV. In univariate analysis the significant risk factors were full blown AIDS status (OR=4.1, 95% CI: 1.49-11.43) and low CD4 T cell count of index partners at enrollment (OR=7.8, 95% CI: 2.19-27.80). In multivariate analysis HIV-1 RNA levels was significant risk factor when adjusted by CD4 T cell courts and mean sexual contacts per month (OR=19.2, 95% CI: 1.03-357.59) Conclusion: The risk of male to female heterosexual transmission increased with advanced stages of HIV infection in the index male partners.

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단일의복의 보온력 정량화와 영향 요인 (Quantification of Thermal Insulation by Clothing Items and Analysis of Influencing Factors)

  • 백윤정;황수경;이효현;박준희;김도희;이주영
    • 한국의류학회지
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    • 제42권1호
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    • pp.172-182
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    • 2018
  • The purpose of the present study was to quantify the thermal insulation of garments by item and examine factors influencing clothing insulation. A total of 769 garments in clo unit were collected and classified into 12 categories: blouses/shirts (95 items, BS), T-shirts/sweaters (62 items, TS), vest (23 items, VT), cardigans (23 items, CD), jackets/coats (75 items, JC), sport outerwear (including padding jackets)(48 items, SO), trousers (23 items, TR), skirts (56 items, SK), dresses (28 items, DS), underwear (150 items, UW), sleepwear (50 items, SW), and personal protective clothing (59 items, PPC). The results showed that clothing insulation was $0.21{\pm}0.01clo$ for the BS, $0.22{\pm}0.01clo$ for TS, $0.12{\pm}0.00clo$ for VT, $0.23{\pm}0.02clo$ for CD, $0.40{\pm}0.02clo$ for JC, $0.49{\pm}0.03clo$ for SO, $0.21{\pm}0.01clo$ for TR, $0.18{\pm}0.01clo$ for SK, $0.34{\pm}0.03clo$ for DS, $0.09{\pm}0.01clo$ for UW, $0.42{\pm}0.03clo$ for SW, and $0.56{\pm}0.03clo$ for PPC (p<.001). The most influential factors among the seven factors for thermal insulation of garments were clothing weight and covering area; however, the explanatory powers of two factors differed according to clothing categories. The covering area had more significant impact on clothing insulation in cardigans, jackets/coats, trousers, and dresses than clothing weight. Covering areas and clothing weight were the most influential factors in the following categories: blouses/shirt, T-shirts/sweaters, skirts, sleepwear and personal protective clothing. The garment weight was the most important factor for thermal insulation for the sport outerwear.

한반도의 황사 관측현황 및 배경지역 미세먼지의 화학적 조성에 관한 연구 (Study on the Yellow Sandy Dust Phenomena in Korean Peninsula and Chemical Compositions in Fine Particles at Background Sites of Korea.)

  • 백광욱;정진도
    • 환경위생공학
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    • 제19권4호
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    • pp.9-18
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    • 2004
  • In this study, the observation data for the yellow sandy dust phenomena from the year 1999 to 2003 at background sites in Korea were collected at Global Atmospheric Observatory at An-Myeon island and its temporal variation were analyzed. The chemical characteristics of the fine particles were also analyzed in order to evaluate sources of the yellow sandy dust particles. The results showed that the monthly average mass concentration of the fine particles was the highest in springtime and the lowest in summertime in general. The magnitude of its variation was also the highest in March in which the occurrence of yellow sandy dust was the most frequent and thus the number of samples was the largest, while the lowest in June through September. The yearly variation of ion components contributions to the total mass concentration of the fine particles was slowly decreasing, showing that $63\%$ in 1999, $59\%$ in 2000 and $56\%$ in 2003. The most prevalent ion components in the fine particles were found to be $NO_3$ and $SO_4^{2-}$, which are known to be source materials of acidic precipitation, and $NH_4^+$, a neutralizing material of the acid precipitation. Relative proportion of metal components in the fine particles was calculated as $14\%$ in average, and their concentrations are in an order of Fe > Al > Na > Ca > Zn > Pb > Cu > Mn > Ni > Cd > Cr > Co > U. The results indicated that main sources of the metals was soil-originated Fe, Al, Ca, and Mg, and the contribution of anthropogenic air Pollution-originated Zn, Pb, Cu, Mn were also high and keep slightly increasing. Statistical analysis showed that the chemical components could be divided into soil-originated group of Mg, Al, Ca, Fe, and Mn and air pollution-originated group of $NO_3$, Zn, Pb, and they are occupying more than $60\%$of all the components in the dusty sand. The results explain that An-Myeon island is more influenced by soil-originated source than ocean-originated one and also the influencing strength of anthropogenic poilution-originated source is less than $50\%$ of that of soil-originated sources. Compared to non-yellow sandy period, the yellow sandy dust period showed that the amounts of soil-originated $Mg^{2+}$ and $Ca^{2+}$ and ocean-originated $Na^+$ and $Cl^-$ were increased to more than double and the metals of Mg, Al, Ca, Fe were also highly increased, while micro metal components such as Pb, Cd, Zn, which have a tendency of concentrating in air, were either decreased or maintained at nearly constant level. In the period of yellow sandy dust, a strong positive correlation was observed between water soluble ions and between metals in terms of its concentration, respectively. Factor analysis showed that the first group being comprised of about $43\%$ of the total inorganic components was affected by soil and they are ions of $Na^+,\;Mg^{2+}\;and\;Ca^{2+}$ and metals of Na, Fe, Mn and Ni. The result also showed that the metals of Mg and Cr were classified as second group and they were also highly affected by soil sources.