• Title/Summary/Keyword: CD206

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Manufacturing of 2025 Coin Type PAn/Li-Al Secondary Battery (2025 Coin형 PAn/Li-Al 2차전지의 제조)

  • Moon, Seong-In;Yun, Mun-Soo
    • Proceedings of the KIEE Conference
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    • 1990.07a
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    • pp.202-206
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    • 1990
  • The existing batteries such as lead acid battery and Nicad battery have been at serious issue, because heavy metal such as Pb and Cd give rise to environmental pollution. Therefor, when these material is changed over polymeric electroactive material, we expect environmental pollution will be prevented. We decided to develop 2025 coin type PAn/Li-Al secondary battery for goal of memory back-up battery. This report is concerned with manufacturing of 2025 coin type PAn/Li -Al secondary battery.

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A Study on Mixture Composition and Combustion Characteristics in Gasoline Engine (가솔린 기관의 혼합기 조성과 연소 특성에 관한 연구)

  • Kim, Gi-Bok;Yoon, Chang-Sik
    • Journal of the Korean Society of Industry Convergence
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    • v.18 no.4
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    • pp.197-206
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    • 2015
  • Recently the automobile engine has been developed in achieving the high performance, fuel economy, and emission reduction. In a conventional spark ignition engine the fuel and air are mixed together in the intake system, inducted through the intake valve into the cylinder, and then compressed. Under normal operating conditions, the combustion is initiated towards the end of the compression stroke at the spark plug by an electric discharge. Following inflammation, a flame develops and propagates through this premixed fuel-air mixture. Therefore the state of mixture is very important in the combustion and emission characteristics. In this study the combustion and emission characteristics were tested and analyzed with changing the mixture composition and engine operating parameters in order to improve the combustion and performance in engine.

Biosorption of Metal Ions by Seaweed Alginate, Polyguluronate, and Polymannuronate (알긴산, 폴리글루론산 및 폴리만뉴론산에 의한 금속이온의 흡착)

  • Jung, Dae-Young;Son, Chang-Woo;Kim, Sung-Koo;Kim, Yi-Joon;Chung, Chung-Han;Lee, Jin-Woo
    • Journal of Life Science
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    • v.19 no.5
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    • pp.553-560
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    • 2009
  • Based on $P_{1/2}$ values, relative affinities of alginate, polyguluronate, and polymannuronate for metal ions are, in order, as follows; 1) seaweed alginate: $Cu^{2+}$ > $Cd^{2+}$ > $Pb^{2+}$ > $Fe^{3+}$ >> $Zn^{2+}$ > $Sr^{2+}$ > $Ca^{2+}$ > $Co^{2+}$ >> $Cr^{6+}$ > $Mn^{2+}$ >> $Hg^{2+}$, $Mg^{2+}$, $Rb^+$, 2) polyguluronate: $Cd^{2+}$ > $Cu^{2+}$ > $Pb^{2+}$ > $Fe^{3+}$ >> $Ca^{2+}$ > $Sr^{2+}$, $Zn^{2+}$, $Co^{2+}$ >> $Mn^{2+}$ > $Cr^{6+}$ >> $Hg^{2+}$, $Mg^{2+}$, $Rb^+$, and 3) polymannuronate: $Cd^{2+}$, $Cu^{2+}$ > $Fe^{3+}$ > $Pb^{2+}$ > $Ca^{2+}$ > $Zn^{2+}$ > $Sr^{2+}$ > $Co^{2+}$ > $Cr^{6+}$ >> $Mn^{2+}$ >> $Hg^{2+}$, $Mg^{2+}$, $Rb^+$. Amounts of the metal ions, $Cd^{2+}$, $Cu^{2+}$, $Fe^{3+}$, $Pb^{2+}$, and $Zn^{2+}$, bound to 1 g of seaweed alginate, were measured as $363.5{\pm}45.0$, $226.3{\pm}9.2$, $1,299.4{\pm}$81.3, 500.7${\pm}$27.7, and 165.9${\pm}$11.4 mg, respectively. Amounts of the metal ions, $Cd^{2+}$, $Cu^{2+}$, $Fe^{3+}$, $Pb^{2+}$, and $Zn^{2+}$, bound to 1g of polyguluronate, were 354.5${\pm}$26.5, 177.6${\pm}$8.7, 1,288.6${\pm}$60.1, 424.0${\pm}$7.4, and 140.2${\pm}$28.5 mg, respectively, whereas those bound to 1 g of polymannuronate were 329.0${\pm}$10.3, 206.9${\pm}$1.9, 1,635.6${\pm}$11.1, 419.8${\pm}$12.6, and 251.0${\pm}$49.1 mg, respectively. Due to its higher solubility than alginate and higher affinity for metal ions than polyguluronate, polymannuronate can be used for bioremediation or biosorption of toxic and/or noble metal ions.

Heavy Metal Contamination of Soils and Stream Sediments at the Sanggok Mine Drainage, Upper Chungju Lake, Korea (충주호 상류, 상곡광산 수계에 분포하는 토양과 하상퇴적물의 중금속 오염)

  • 이현구;이찬희
    • Journal of the Korean Society of Groundwater Environment
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    • v.5 no.1
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    • pp.10-20
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    • 1998
  • Heavy metal contamination in subsurface soils and stream sediments at the Suggok mine area were investigated on the basis of major, trace and rare earth elements geochemistry and mineralogy. The Sanggok mine area is mainly composed of Cambro-Ordovician carbonate rocks. The mine had been mined for Pb-Zn-Fe and Au- Ag, but already closed in past. For major elements, especially Fe (mean value=18.58 wt.%) and Mn (mean value=4. 18 wt.%) are enriched in soils, and the average enrichment indices of soils and sediments are 6.84 and 1.54, respectively. The average enrichment index of rare earth elements are 0.92 of mining drainage sediments and 0.52 of subsurface soils on the tailing dam. Concentrations of minor and/or environmental toxic elements in those samples range from 29 to 3400 for As,1 to 11 for Cd, 35 to 292 for Cu, 50 to 1827 for Pb, 1 to 22 for Sb and 112 to 2644 for Zn. Extremely high concentrations (mean values) are found in subsurface soils on the tailing dam (As=2278, Cd=7, Cu=206, Pb=1372, Sb=14 and Zn=2231 ppm, respectively). Average enrichment index normalized by composition of non-mining drainage sediments is 2.42 in mining drainage sediments and 25.47 in subsurface soils on the tailing dam. Based on EPA value, enrichment index of toxic elements is 0.53 in non-mining drainage sediments, 1.84 in mining drainage sediments and 23.71 in subsurface soils on the tailing dam. As a results from X-ray powder diffraction method, mineral composition of soils and sediments near the mine area varied in part, and are calcite, dolomite, magnesite, quartz, mica, chlorite and clay minerals. With the separation of heavy minerals, soils and sediments of highly concentrated toxic elements included some pyrite, arsenopyrite, sphalerite, galena, goethite and hydroxide minerals on the polished sections.

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Glutamine and Leucine Provide Enhanced Protective Immunity Against Mucosal Infection with Herpes Simplex Virus Type 1

  • Uyangaa, Erdenebileg;Lee, Hern-Ku;Eo, Seong Kug
    • IMMUNE NETWORK
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    • v.12 no.5
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    • pp.196-206
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    • 2012
  • Besides their role as building blocks of protein, there are growing evidences that some amino acids have roles in regulating key metabolic pathways that are necessary for maintenance, growth, reproduction, and immunity. Here, we evaluated the modulatory functions of several amino acids in protective immunity against mucosal infection of herpes simplex virus type 1 (HSV-1). We found that glutamine (Gln) and leucine (Leu) showed enhanced protective immunity to HSV-1 mucosal infection when two administration of Gln and single administration of Leu per day, but not when administered in combinations. Ameliorated clinical signs of HSV-1 challenged mice by the intraperitoneal administration of Gln and Leu were closely associated with viral burden and IFN-${\gamma}$ production in the vaginal tract at 2 and 4 days post-infection. In addition, the enhanced production of vaginal IFN-${\gamma}$ appeared to be caused by NK and HSV-1 antigen-specific Th1-type CD4+ T cells recruited into vaginal tract of mice treated with Gln and Leu, which indicates that IFN-${\gamma}$, produced by NK and Th1-type CD4+ T cells, may be critical to control the outcome of diseases caused by HSV-1 mucosal infection. Collectively, our results indicate that intraperitoneal administration of Gln and Leu following HSV-1 mucosal infection could provide beneficial effects for the modulation of protective immunity, but dosage and frequency of administration should be carefully considered, because higher frequency and overdose of Gln and Leu, or their combined treatment, showed detrimental effects to protective immunity.

A study on the characteristics of pollutants on bottom sediments in Shin-Gal Reservoir (신갈호 저층 퇴적물에 대한 오염물질 특성에 관한 연구)

  • Ahn, Tae-Woong;Kim, Tae-Hoon;Lee, Sang-Eun;Kim, Sang-Hyeon;Choi, I-Song;Oh, Jong-Min
    • Proceedings of the Korea Water Resources Association Conference
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    • 2011.05a
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    • pp.202-206
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    • 2011
  • 본 연구에서는 정체성 수역인 신갈호를 대상으로 저층 퇴적물의 오염물질에 대한 조사를 실시 하였다. 신갈호 저층 퇴적물의 분석 결과, 함수율의 범위는 49.0~68.2%로 조사되었으며, 평균 함수율은 60.8%로 나타났다. 함수비의 경우에는 지점별 96.1~214.6%의 넓은 범위를 보였으며 평균 함수비는 165.8%로 조사되었다. 퇴적물의 pH는 모든 지점에서 산성을 띄었으며, 하류부로 갈수록 더욱 낮아지는 경향을 보였다. 입도분석 결과, 토성은 SL(사양토) 및 SiL(실트질양토)로 나타났으며, 이러한 토성분포는 입자별 침강속도에 의한 것으로 퇴적물의 지점별 이 화학적 특성에 많은 영향을 줄 것으로 판단된다. 유기물 함량 분석결과, 강열감량의 경우 8.22~11.36%로 평균 10.22% 의 유기물 함량을 보였으며, COD는 24,92 mg/kg~27,38 mg/kg의 값으로 평균 26,16 mg/kg로 조사되었다. 영양물질 함량 분석결과, T-N의 경우 신갈호 저층 퇴적물 평균 2,916 mg/kg의 질소 함량을 보였으며, T-P의는 평균 710 mg/kg로 조사되었다. 영양물질 함량 분석결과 하류부로 갈수록 높아지는 경향을 보였으나 총질소의 경우 지점별 비슷한 값을 보인 반면, 총인은 지점별 큰 차이를 보였다. 퇴적물의 중금속 함량은 Cd, Cu, Zn, $Cr^{6+}$, Pb을 분석하였으며, Cd 0.10~0.12 mg/kg, Cu 18.33~20.67 mg/kg, Zn 82.73~110.15 mg/kg, $Cr^{6+}$ 0.78~0.93 mg/kg Pb 11.04~14.53 mg/kg의 범위를 보였으며, 지점별로 큰 차이를 보이지 않았다. 본 연구의 자료는 신갈호 유역의 개발계획 및 준설 검토에 대한 유용한 자료로 활용 가능할 것으로 판단된다.

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The Value of Interleukin-12 as an Activity Marker of Pulmonary Sarcoidosis (폐유육종증의 활동성 지표로서 IL-12의 효용성에 관한 연구)

  • Kim, Tae-Hyung;Jeon, Yong-Gam;Shim, Tae-Sun;Lim, Chae-Man;Koh, Yun-Suck;Lee, Sang-Do;Kim, Woo-Sung;Kim, Won-Dong;Kim, Dong-Soon
    • Tuberculosis and Respiratory Diseases
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    • v.46 no.2
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    • pp.215-228
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    • 1999
  • Background: Sarcoidosis is a chronic granulomatous inflammatory disease of unknown etiology often involving the lungs and intrathoracic lymph nodes. The natural course of sarcoidosis is variable from spontaneous remission to significant morbidity or death. But, the mechanisms causing the variable clinical outcomes or any single parameter to predict the prognosis was not known. In sarcoidosis, the number and the activity of CD4 + lymphocytes are significantly increased at the loci of disease and their oligoclonality suggests that the CD4 + lymphocytes hyperreactivity may be caused by persistent antigenic stimulus. Recently, it has been known that CD4+ lymphocytes can be subdivided into 2 distinct population(Th1 and Th2) defined by the spectrum of cytokines produced by these cells. Th1 cells promote cellular immunity associated with delayed type hypersensitivity reactions by generating IL-2 and IFN-$\gamma$. Th2 cells playa role in allergic responses and immediate hypersensitivity reactions by secreting IL-4, IL-5, and IL-10. CD4+ lymphocytes in pulmonary sarcoidosis were reported to be mainly Th1 cells. IL-12 has been known to play an important role in differentiation of undifferentiated naive T cells to Th1 cells. And, Moller et al. observed increased IL-12 in bronchoalveolar lavage fluid(BALF) in patients with sarcoidosis. So it is possible that the elevated level of IL-12 is necessary for the continuous progression of the disease in active sarcoidosis. This study was performed to test the assumption that IL-12 can be a marker of active pulmonary sarcoidosis. Methods: We measured the concentration of IL-12 in BALF and in conditioned medium of alveolar macrophage(AM) using ELISA(enzyme-linked immunosorbent assay) method in 26 patients with pulmonary sarcoidosis(10 males, 16 females, mean age: $39.8{\pm}2.1$ years) and 11 normal control. Clinically, 14 patients had active sarcoidosis and 12 patients had inactive. Results: Total cells counts, percentage and number of lymhocytes, number of AM and CD4/CD8 lymphocyte ratio in BALF were significantly higher in patients with sarcoidosis than in control group. But none of these parameters could differentiate active sarcoidosis from inactive disease. The concentration of IL-12 in BALF was significantly increased in sarcoidosis patients ($49.3{\pm}9.2$ pg/ml) than in normal control ($2.5{\pm}0.4$ pg/ml) (p<0.001). Moreover it was significantly higher in patients with active sarcoidosis ($70.3{\pm}14.8$ pg/ml) than in inactive disease ($24.8{\pm}3.l$ pg/ml) (p=0.001). Also, the concentration of IL-12 in BALF showed significant correlation with the percentage of AM(p<0.001), percentage(p<0.001) and number of lymphocyte(p<0.001) in BALF, suggesting the close relationship between the level of IL-12 in BALF and the inflammatory cell infiltration in the lungs. Furthermore, we found a significant correlation between the level of IL-12 and the concentration of soluble ICAM-1 : in serum(p<0.001) and BALF (p=0.001), and also between IL-12 level and ICAM-1 expression of AM(p<0.001). The AM from patients with pulmonary sarcoidosis secreted significantly larger amount of IL-12 ($206.2{\pm}61.9$ pg/ml) than those of control ($68.3{\pm}43.7$ pg/ml) (p<0.008), but, there was no difference between inactive and active disease group. Conclusion : Our data suggest that the BALF IL-12 level can be used as a marker of the activity of pulmonary sarcoidosis.

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Development of 2.32-inch $320{\times}350$ LTPS TFT-LCD for Advanced Mobile Phones Using SLS Technology

  • Zhang, Lintao;Kang, Myung-Koo;Lee, Joong-Sun;Park, Jong-Hwa;Joo, Seung-Yong;Moon, Kuk-Chul;Kim, Il-Kon;Kim, Sung-Ho;Park, Kyung-Soon;Yoo, Chun-Ki;Kim, Chi-Woo
    • 한국정보디스플레이학회:학술대회논문집
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    • 2005.07b
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    • pp.1035-1037
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    • 2005
  • 2.32-inch $320{\times}350$ TFT-LCD with high resolution (206PPI) for advanced mobile phones could be successfully developed. The compact pixel design based on PMOS SLS technique is used to achieve this high resolution. Gate driver and part of data driver are integrated onto the glass substrate. High brightness (170cd) and contrast ratio (400:1) were obtained with very low flickering and crosstalk levels.

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Resveratrol Ameliorates High-fat-induced Metabolic Complications by Changing the Expression of Inflammasome Markers and Macrophage M1 and M2 Markers in Obese Mice (라스베라트롤 투여가 고지방식이 비만쥐의 지방조직에서의 inflammasome과 대식세포 마커에 미치는 영향)

  • Lee, Young-Ran;Pitriani, Pipit;Park, Hee-Geun;Lee, Wang-Lok
    • Journal of Life Science
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    • v.27 no.12
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    • pp.1462-1469
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    • 2017
  • The purpose of this study was to investigate the effects of resveratrol supplementation on inflammasome, inflammation, and macrophage markers in subcutaneous adipose tissue of high-fat-diet-induced obese mice. C57BL/6 mice were randomly assigned to three groups: normal diet control (NC; n=10), high-fat diet control (HC; n=10), or high fat with resveratrol (HRE; n=10) group. The mice were fed a high-fat diet (60% of calories from fat) or normal diet (18% of calories from fat). Resveratrol dissolved in a 0.1ml solution of dimethyl sulfoxide was supplemented orally at 25 mg/kg body weight. After 15 weeks, the body weight was significantly higher in the high-fat diet group than in the normal diet group. The inflammasome markers NLRP3, ASC, and caspase1 were significantly lower in the HRE group than in the HC group. The levels of an inflammation marker, IL-18, were also significantly lower in the HRE group than in the NC and HC groups. The levels of macrophage markers F480 and CD86 were significantly lower in the HRE group than in the HC group. The levels of the M2 macrophage marker CD206 were significantly decreased in the HC and HRE groups. Resveratrol had a positive effect on ameliorating the complications of high fat diet-induced obesity by reducing inflammasome and M1 macrophage gene expressions. However, resveratrol supplementation did not reduce inflammation gene expression.

Effect of Raw Broun Rice and Job식s Tear Supplemented Diet on Serum and Hepatic Lipid Concentrations, Antioxidative System, and Immune Function of Rats (현미 및 율무 함유 생식이 영양불균형이 유도된 흰쥐의 체내 지질농도, 항산화체계 및 면역기능에 미치는 영향)

  • 박진영;양미자;전혜승;이진희;배희경;박태선
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.2
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    • pp.197-206
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    • 2003
  • Physiological functions of raw grain diet composed of brown rice and Job's Tear (1 : 1) were evaluated in rats raised with nutritionally unbalanced diet including 1% cholesterol, high proportion of animal lipids (lard: soybean oil : 8 : 2), sub-optimal levels of vitamin and mineral mixture along with 0.5% ethanol in drinking water for 4 weeks. Control rats were fed the AIN-93G diet for 9 weeks, and nutritionally unbalanced rats were divided into 3 groups, and fed one of the following diets with 0.5% ethanol in drinking water for another 5 weeks: unbalanced control diet (UCD), raw grain diet (RGD) (UCD +20% brown rice and Job's Tear mixture, and cooked grain diet (CGD)(autoclaved RGD at 121$^{\circ}C$ for 3 hours). Feeding UCD for 5 weeks significantly lowered the food efficiency ratio (FER) of rats than the value for control animals, and dietary supplementation of brown rice and Job's Tear mixture to UCD significantly restored the FER. Serum total cholesterol concentration was significantly lowered in rats fed RGD (24% decrease) or CGD (16% decrease) compared to the value for rats fed UCD. Feeding RGD for 5 weeks significaly lowered the serum LDL+VLDL-cholesterol concentration (26% decrease), as well as the hepatic cholesterol level (16% decrease) than the values for UCD rats. Animals fed CGD (38% decrease) or RGU (59% decrease) showed significantly lower level of hepatic thiobarbituric acid reactive substances (TBARS) compared to the value for rats fed UCD (p<0.05), although hepatic activities of antioxidative enzymes were not influenced by dietary supplementation. Feeding RGD for 5 weeks significantly increased CD4$^{+}$ T-cell population along with CD4$^{+}$/CD8$^{+}$ ratio of mesenteric lymph nodes compared to those for UCD rats (p<0.05). In conclusion, dietary supplementation of brown rice and Job's Tear mixture as raw grains exhibited superior activity lowering blood and hepatic levels of cholesterol, and improving mesenteric lymph nodes immune function of rats to the cooked grain mixture of identical ingredients.