• Title/Summary/Keyword: CCI₄

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Effect of Carbon Tetrachloride Intoxication on the Type Conversion of Xanthine Dehydrogenase Into Xanthine Oxidase in Rats

  • Yoon, Chong-Guk;Huh, Keun
    • Archives of Pharmacal Research
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    • v.10 no.1
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    • pp.36-41
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    • 1987
  • The conversion of xanthine dehydrogenase (type D) into xanthine oxidase (type D) was significantly increased in serum and liver of all $CCI_4$ treated rats on the necrosis and early cirrhosis stage of liver tissue. In the pretreatment of prednisolone, the ratio of type O per type O + D showed the decreasing tendency in serum, but the significant decrease in liver. In vitro, the conversion of liver xanthine oxidase from type D into type O was markedly increased by following preincubation with lysosomal fraction. The type conversion of xanthine oxidase may be caused by protelytic enzymes in lysosome.

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An Improved V-BLAST Receiver based on Relibability Normalization (신뢰성 정규화를 기반으로 한 개선된 V-BLAST 수신기 구조에 관한 연구)

  • Kim, Hyoun-Kuk;Park, Hyun-Cheol
    • Proceedings of the IEEK Conference
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    • 2004.06a
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    • pp.71-74
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    • 2004
  • We present an improved V-BLAST receiver that cancels co-channel interference (CCI), based on reliability normalization over frequency-selective channels, in log-likelihood ratio (LLR) sense. The performance has been evaluated in the exponential decay channel model with various normalized ms delay spread and different filter taps. It is also compared with the ordered successive interference cancellation-decision feedback equalizer (OSIC-DFE). Simulation results show that the performance of the proposed receiver with (2,1) is close to OSIC-DFE with (6,3) at normalized ms delay spread 0.5 symbol periods.

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Study on the $\delta$-endotoxin by Bacillus thuringiensis subsp. indiana(TH109) (Bacillus thuringiensis subsp. indlana(TH109)가 생산한 $\delta$-endotoxin에 관한 연구)

  • 이광배;채용곤
    • Journal of environmental and Sanitary engineering
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    • v.9 no.1
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    • pp.89-96
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    • 1994
  • This report was investigate the biological characteristic of $\delta$-endotoxin of product by TH109 strain, one strain TH109 which has toxicity on Cockroach is isolate and identification. Generally the $\delta$-endotoxin of product by 3. thuringiensis strain was easily soluble in acid, alkaline and organic solvents but $\delta$-endotoxin of product by TH109 strain are insoluble in HCI, NaOH Thiol- reagent(25mM Dithiotheritol, 25mM Dithioeryritol, 25mM Nathioglycolate, 0.2M ESCN, 2% v/v $\beta$-mecaptethanol), organic solvents( acetone, $CCI_{4}$, ether, dioxin MeOH chloroforrh xylene ), Protease. Through this study of $\delta$-endotoxin produced by TH109 strain is insoluble in acid, alkaline, organic solvents and pretense etc. In the point of view, it is greater possibility that $\delta$-endotoxin will be transform into toxin by the reducible materials instead of the reaction of protease in the intestine.

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국내 임상시험의 현재와 미래

  • 이훈주
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1997.11a
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    • pp.51-55
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    • 1997
  • 국내 신약 1호를 기다리며, 현재 우리나라의 임상시험 현 주소와 앞으로 나아가야 할 방향에 관하여 한번쯤 검토하고, 어떻게 임상시험의 수준을 선진국 수준으로 끌어올릴 수 있는지 검토할 필요가 있다. 졔약 산업은 요즘 한창 주가를 높이고 있는 정보 통신 분야 만큼이나 고부가가치 산업이다. 때문에 정부의 주도하에 제약 기업 부설연구소 및 정부출연구소에서 의약품 개발과 관련한 연구 수행 과제 중 신약 개발 연구과제가 약 200여 가지나 되며, 이중 임상시험 단계가 10과제로 현재 임상시험이 진행되고 있다. 따라서 머지않아 이러한 노력에 대한 결실을 기대할 수 있을 것이다. 특히, 신약 개발은 인류의 건강, 복지와 밀접한 관련을 맺고 있으며, 기초 학문과 응용 분야의 접목이 필수적인 분야이다. 그러나, 하나의 신약을 개발하기 위해서는 평균 12년이라는 긴 세월의 개발 기간과 약 1,800억이라는 천문학적인 비용이 소요되기 때문에 쉽게 투자하지 못하는 산업이기도 하다. 때문에 잠시 한 걸음 옆에서 첨단 산업 분야로 신약 개발을 계속 추진하여야 할지 고민할 필요가 있다. 우리에게 이러한 자본, 인력, 시간이 충분치 않기 때문이다. 아마도 선진국으로 진입하기 위한 커다란 관문일지도 모른다. 하지만 포기할 수 없는 산업이기 때문에 어떻게 하면 우리의 목적을 달성할 수 있는지 그 방안을 모색하는 것이 현 상황에 대한 올바른 판단일 것이다.

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Performance Evaluation of Direct Broadcasting Satellite Channel using a MC and QA Method (MC기법과 QA기법을 이용한 직접위성방송채널 성능평가)

  • 정지원;조형래;고성찬
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.3 no.4
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    • pp.839-847
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    • 1999
  • This paper presents the performance evaluation of direct broadcasting satellite by monte-carlo(MC) and quasi-analytic(QA) simulation method in the existence of uplink/downlink adjacent channel interference(ACI), co-channel interference(CCI), and gaussian noise. Korea's satellite system parameters and link design are used at the simulation. MC and QA simulation methods are a valuable adjunct to analytical performance.

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Evaluation of Hepatoprotective Potential of Cassia tora Leaf Extract

  • Maity, Tapan Kumar;Mandal, Subhash C.;Mukherjee, Pulok K.;Saha, Kakali;Das, J.;Saha, B.P.;Pal, M.
    • Natural Product Sciences
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    • v.3 no.2
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    • pp.122-126
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    • 1997
  • Methanolic extract of the leaves of Cassia tom was evaluated for its hepatoprotective potentials in rats by inducing hepatotoxicity with carbon tetrachloride. The extract at a dose of 400 mg/kg orally showed significant protective effect by lowering the serum levels of transaminase (SGOT and SGPT), bilirubin and alkaline phosphatase (ALP). The effects produced were comparable to that of a standard hepatoprotective agent.

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The Tree Growth and Breakdown Characteristics of Unsaturated Polyester Dissolving the Electronegative Gases (부성기체를 용해시킨 불포화 폴리에스터의 Tree 성장과 절연파괴 특성)

  • 이보호;전춘생
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.41 no.2
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    • pp.178-184
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    • 1992
  • This study treats the improvement of the dielectric strength of polymer by eliminating the air in it and dissolving electronegative gases. As experimental material, unsaturated polyester resin was used and the specimen was made by dissolving NS12T. SFS16T abd CCIS12TFS12T gases which have strong electron affinity. And also the electrical properties (tree growth and breakdown characteristics) of them were tested and discussed. The results are as follows. When the specimen dissolved with electronegative gas compared with one with air` 1) The tree breakdown voltage of the former is higher than that of the latter. 2) The tree growth of the former is slower than that of the latter. 3) The temperature dependence of the former is smaller than that of the latter. 4) The breakdown voltage of the specimen dissolved with electronegative gas is much higher than that dissolved with air.

A Multi-Dimensional Radio Resource Scheduling Scheme for MIMO-OFDM Wireless Systems

  • Li, Lei;Niu, Zhisheng
    • Journal of Communications and Networks
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    • v.8 no.4
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    • pp.401-409
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    • 2006
  • Orthogonal frequency division multiplexing (OFDM) and multiple input multiple output (MIMO) technologies provide additional dimensions of freedom with spectral and spatial resources for radio resource management. Multi-dimensional radio resource management has recently been identified to exploit the full dimensions of freedom for more flexible and efficient utilization of scarce radio spectrum while provide diverse quality of service (QoS) guarantees. In this work, a multi-dimensional radio resource scheduling scheme is proposed to achieve above goals in hybrid orthogonal frequency division multiple access (OFDMA) and space division multiple access (SDMA) systems. Cochannel interference (CCI) introduced by frequency reuse under SDMA is eliminated by frequency division and time division between highly interfered users. This scheme maximizes system throughput subjected to the minimum data rate guarantee. for heterogeneous users and transmit power constraint. By numerical examples, system throughput and fairness superiority of the our scheduling scheme are verified.

Performance Analysis of IMT-2000 System with Improvement Rake Receiver (개선된 레이크 수신기를 채용하는 IMT-2000 시스템의 성능 분석)

  • 소준영;우병훈;강희조
    • Proceedings of the Korea Electromagnetic Engineering Society Conference
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    • 2000.11a
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    • pp.39-43
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    • 2000
  • 본 논문에서는 IMT-2000 시스템에 대한 제안된 표준안을 기초로 송수신 시스템을 구성하여 광대역 무선채널 환경 및 다양한 시스템 운용환경에서 시스템의 성능을 분석한다. 수신 성능의 개선을 위하여 CCI(Co-Channel Interference) Canceller와 Rake 수신기를 혼합하여 기존의 Rake 수신기에서 제거할 수 없었던 자기 간섭(Auto Interference)을 제거하는 새로운 Rake수신기를 제안하였다. 또한 다중 경로 페이딩 모델로는 ITU-R M.1225에서 제시된 모델을 적용하였다. 성능 분석 결과, 상대적으로 작은 지연 확산을 가지는 채널 A가 중간 지연 확산을 가지는 채널 B보다 수신성능이 양호함을 알 수 있었으며, 채널 A와 B에 관계없이 제안된 레이크 수신기를 채용하였을 경우 자기 간섭의 제거 효과로 인해 수신성능이 기존의 레이크 수신기를 채용하였을 경우에 비해 향상됨은 알 수 있었다. 또한 간섭제거기와 제안된 레이크 수신기를 직렬로 연결한 수신기를 채용하였을 경우 다중접속간섭을 효과적으로 제거할 수 있었으며, 수신성능의 차이는 채널 환경이 양호할수록, $E_{b/}$N/ sub o/값이 커질수록 차이가 커짐을 알 수 있었다.다.

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