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Solution Methods for Reliability Optimization of a Series System with Component Choices (부품선택이 존재하는 직렬시스템의 신뢰성 최적화 해법)

  • Kim, Ho-Gyun;Bae, Chang-Ok;Kim, Jae-Hwan;Son, Joo-Young
    • Journal of Korean Institute of Industrial Engineers
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    • v.34 no.1
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    • pp.49-56
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    • 2008
  • Reliability has been considered as an important design measure in various industrial systems. We discuss a reliability optimization problem with component choices (ROP-CC) subject to a budget constraint. This problem has been known as a NP-hard problem in the reliability design fields. Several researchers have been working to find the optimal solution through different heuristic methods. In this paper, we describe our development of simulated annealing (SA) and tabu search (TS) algorithms and a reoptimization procedure of the two algorithms for solving the problem. Experimental results for some examples are shown to evaluate the performance of these methods. We compare the results with the solutions of a previous study which used ant system (AS) and the global optimal solution of each example obtained through an optimization package, CPLEX 9.1. The computational results indicate that the developed algorithms outperform the previous results.

A Sedimentation Level in Pituitary Adenoma on Magnetic Resonance Imaging - Case Report - (자기공명촬영에서 침강 레벨을 나타낸 뇌하수체 선종 - 증 례 보 고 -)

  • Kim, Young-Rae;Song, Jun-Hyeok;Park, Hyang-Kwon;Kim, Sung-Hak;Shin, Kyu-Man
    • Journal of Korean Neurosurgical Society
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    • v.30 no.4
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    • pp.518-521
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    • 2001
  • We present a rare case of a pituitary adenoma revealing a sedimentation level on MRI, which has not been previously documented. This 55-year-old woman was referred with the diagnosis of craniopharyngioma. She presented with four-month history of progressive headache and visual dimness. Neurological examination revealed a bitemporal hemianopsia and decreased visual acuity. Laboratory data including endocrine examination were unremarkable. An additional three-dimensional MRI was taken for further evaluation, and demonstrated a sedimentation level within the tumor. The patient underwent transcranial removal of the tumor. About 12cc of dark-red blood was aspirated from the tumor. Histological examination revealed a pituitary adenoma with hemorrhage. Postoperatively, the patient showed gradual improvement of visual function. Considering that the pituitary adenoma is one of more common tumors that cause tumoral bleeding, a cystic sellar tumor that has a sedimentation level should be sought first for a pituitary adenoma rather than a craniopharyngioma. This may have an important impact when deciding surgical approach.

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The Effects of Aroma Hand Massage on Sleep and Depression in Hospitalized Elderly Patients (아로마테라피 손 마사지가 입원 노인의 수면 및 우울에 미치는 효과)

  • Kim, Yang-Hee;Kim, Youn-Chul;SaKong, Jeong-Kyu
    • Journal of Society of Preventive Korean Medicine
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    • v.13 no.3
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    • pp.73-85
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    • 2009
  • Objectives : To evaluate the effects of aroma hand massage on sleep disturbance and depression in hospitalized elderly patients. Methods : The data was collected using questionnaires from the subjects who were admitted to the G Medical Hospital in Daegu from 7 July to 12 July, 2008. A total of 23 subjects were selected. The subjects were applied with the aroma hand massage to both hands using a solution diluting four drops of lavender oil in jojoba oil 10cc. Aroma hand massage was given for 10 minutes, one time a day, during 5 days. Results : There was statistically significant improvement on the Korean sleep scale(t=-7.614, p=0.000) and on the Geriatric Depression Scale Short Korea Version(GDSSF-K)(t=3.444, p=0.002). Conclusions : aroma hand massage is an effective therapeutic intervention for decreased sleep disturbance and depression. Therefore, aroma therapy and hand massage by therapeutic intervention is recommended for improving psychological and physiological functions in hospitalized elderly patients.

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Method Validation for the Simultaneous Analysis of Organophosphorous Pesticides in Blood by GC/MS (GC/MS를 이용한 혈액 중 유기인제류 농약의 동시 분석에 관한 방법의 유효화)

  • Park Mee Jung;Yang Ja Youl;Kim Ki Wook;Park Yoo Shin;Chung Hee Sun;Lee Sang Ki
    • Environmental Analysis Health and Toxicology
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    • v.20 no.4 s.51
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    • pp.297-302
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    • 2005
  • The purpose of this study was to provide the standard method for the analysis of organophosphorous pesticides such as chlorpyrifos, diazinon, malathion and parathion in blood. We performed method validation for these pesticides in blood according to EURACHEM (A focus For Analytical Chemistry in Europe) guide. For the analysis of the pesticides, we used solid-phase extraction ,column (Waters Oasis $HLB^{(R)}$. After the extraction, the supernatants were evaporated to dryness under the nitrogen stream. They were analyzed by gas chromatography/mass spectrometry (GC/MS) after reconstituting with ethanol. Terbufos was used as an internal standard. To validate this method, we performed verification procedures with the following parameters: selectivity, linearity of calibration, accuracy, precision, limit of detection and quantification. Validation data according to Eurachem guide were adequate for our purpose for the analysis of chlorpyrifos, diazinon, malathion and parathion in blood.

Methylenetetrahydrofolate Reductase Gene Germ-Line C677T and A1298C SNPs are Associated with Colorectal Cancer Risk in the Turkish Population

  • Ozen, Filiz;Sen, Metin;Ozdemir, Ozturk
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.18
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    • pp.7731-7735
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    • 2014
  • Colorectal cancer (CRC) is the third most common cause of death due to cancer in the worldwide and the incidence is also increasing in Turkey. Our present aim was to investigate any association between germ-line methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and CRC risk in Turkey. A total of 86 CRC cases and 212 control individuals of the same ethnicity were included in the current study. Peripheral blood-DNA samples were used for genotyping by StripAssay technique, based on the reverse-hybridization principle and real-time PCR methods. Results were compared in Pearson Chi-square and multiple logistic regression models. The MTHFR 677TT (homozygous) genotype was found in 20.9% and the T allele frequency 4.2-fold increased in CRC when compared with the control group.The second SNP MTHFR 1298CC (homozygous) genotype was found in 14.0% and the C allele frequency 1.4-fold elevated in the CRC group. The current data suggest strong associations between both SNPs of germ-line MTHFR 677 C>T and 1298 A>C genotypes and CRC susceptibility in the Turkish population. Now the results need to be confirmed with a larger sample size.

Industrial Waters of Taegu City and on the Objection of Iron for Water Softening (大邱市의 工業用水와 鐵의 軟化障害에 關하여)

  • Lee, Dae-Soo;Hong, Soon-Yung
    • Journal of the Korean Chemical Society
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    • v.6 no.2
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    • pp.117-121
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    • 1962
  • The waters throughout Taegu area for 87 points were analysed and according to the analytical data, following unfavorable characteristics for industrial uses were given: (1)Shows strong hardness, (2)Has high ratio of ignition residue to evaporation residue, (3) pH value is over 7, (4) Contains considerable quntities of iron.And then investigated the exchange rate and regeneration level of iron ion using cation exchange resin, Lewatit KS.When the hard water containing 2.2 ppm of iron with 18.4 ppm of calcium and 6.2 ppm of magnesium was passed through the ion exchange resin under $3cc/cm^2/min$ in exhaustant flow rate, exchange rate of iron reached to 42% after 300 hours flow. The exchange efficiency shows abrupt decreasing in initial stage of flow up to 100 hours flow. The exchanger which contains iron was regenerated with 10% sodium hydroxide aqua solution under SV (space velocity) 4. By this method, 57% of iron was eliminated from exchanger while calcium and magnesium are removed as much as 85% and 87% respectively.

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Characteristics of Pressure wave Pulsation at Carburetor on Small SI Engine (소형엔진 기화기 내의 흡기 맥동 특성)

  • Oh, J.W.;Choi, Y.H.;Kim, B.G.;Lee, D.G.;Kim, D.S.;Yoon, S.J.
    • Journal of ILASS-Korea
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    • v.14 no.1
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    • pp.34-38
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    • 2009
  • This paper presents the pulsation of carburetor inlet and outlet pressure of a small SI gasoline engine. The engine used in this paper is a 23cc, single cylinder, diaphragm carburetor, two-stroke, air-cooled for brush cutter. The rpm and pressure wave pulsation at the inlet and the outlet of carburetor were measured and analysed for the understand of the internal air flow into the barrel on the diaphragm carburetor. These data should be used for the development of the duel fuel injection system for gasoline and LPG. The results showed that the carburetor inlet pressure variations were very steady, but the pressure variations at carburetor outlet were very sensitive to the pressure variation into the crank case and were to similar independently to the engine speed on partial opened throttle conditions. According to increasing engine speed, the pressure waves started to come out and be developed after closing the intake port of the engine at carburetor outlet. Reverse flow occurred on the WOT (wide open throttle) condition.

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Development of An Expert System for Classifying and Identifying Asbestos Fibers in the Indoor Air (실내공기 중 석면 섬유의 분류 및 확인을 위한 전문가 시스템의 개발)

  • 김수환;김동술
    • Journal of Korean Society for Atmospheric Environment
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    • v.15 no.6
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    • pp.703-712
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    • 1999
  • In order to determine the number concentration of asbestos, it is initially necessary to develop a method to identify the type of asbestos. Thus a SEM/EDX was used to obtain both physical and chemical information from known asbestos samples as reference samples. Based on these information, we could make a source profile matrix consisted of a glass fiber and 3 other types of asbestos such as chrysotile, crocidolite, and tremolite. After collinearity test was performed for these sources, we could successfully develop an expert system by C-language to separate and to identify various unknown types of fiber particles. The expert system was perfectly self-verified with original reference data. Then the program was extensively applied to survey indoor and outdoor environment such as a residential area, an elementary school, and underground store, and an auto junkyard. As a result for surveying, a total of 442 individual fibrous particles were well classified into 4 types of particle classes above mentioned; 5.4% of chrysotile, 4.1% of crocidolite, 3.6% of glass fiber, and 86.9% of unknown fibers in terms of number concentration. However, tremolite was not detected in the study sites. All the samples were satisfied with the recommendation level of 0.01 f/cc.

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Effect of Alpha-lactalbumin Gene Polymorphism on Milk Production Traits in Water Buffalo

  • Dayal, S.;Bhattacharya, T.K.;Vohra, V.;Kumar, P.;Sharma, Arjava
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.3
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    • pp.305-308
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    • 2006
  • A genetic study was conducted to elucidate the effect of alpha-Lactalbumin (${\alpha}$-LA) gene polymorphism on milk production traits involving total milk yield and daily milk yield during first lactation in two breeds of water buffaloes namely, Murrah and Bhadawari. Single strand conformation polymorphism (SSCP) was carried out to explore genetic polymorphism present at this locus. For this study, exon 1 region of ${\alpha}$-LA was analyzed. Finally, polymorphism data was associated with milk production traits by employing least square analysis. In Murrah buffalo, five genotypes such as AB, BB, BC, CC and CD and four alleles A, B, C and D were detected whereas in Bhadawari buffalo two genotypes namely, AB and BC and three alleles namely, A, B and C were found. Genotypes showed significant effects ($p{\leq}0.05$) on total milk yield and daily milk yield in Bhadawari buffalo but had non-significant effects on these traits in Murrah buffalo.

Activity Measurement of Zn in Liquid Zn-Cd Alloy Using EMF Method (기전력법을 이용한 용융 Zn-Cd 합금중 Zn의 활동도 측정)

  • Jeong, Seong-Yeop;Jeong, U-Gwang;Park, Jong-Jin
    • Korean Journal of Materials Research
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    • v.12 no.4
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    • pp.283-289
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    • 2002
  • The E.M.F of the galvanic cell with fused salt was measured to determine the activities of zinc at 700-820K over the entire composition range of liquid Zn-Cd alloys. The cell used was as follows: (-) W | Zn(pure) $Zn^{2+}(KCI-LiCl)$ | Zn(in Zn-Cd alloy) | W (+) The activities of zinc in the alloys showed positive deviation from Raoult's law over the entire composition range. The activity of cadmium and some thermodynamic functions such as Gibbs free energy, enthalpy, entropy were derived from the results by the thermodynamic relationship. The comparison of the results and the literature data was made. The liquid Zn-Cd alloy is found to be close to the regular solution. The concentration fluctuations in long wavelength limit, $S_{cc}(o)$, in the liquid alloy was calculated from the results.