• 제목/요약/키워드: CBM+

검색결과 231건 처리시간 0.021초

Relationship Between GSTT1 Gene Polymorphism and Hepatocellular Carcinoma in Patients from China

  • Chen, Jie;Ma, Liang;Peng, Ning-Fu;Wang, Shi-Jun;Li, Le-Qun
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권9호
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    • pp.4417-4421
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    • 2012
  • Objective: The results from studies on associations of the glutathione S-transferase T1 (GSTT1) gene polymorphism and hepatocellular carcinoma (HCC) risk in Chinese populations are still conflicting. This meta-analysis was performed to evaluate the relationship in detail. Methods: Eligible reports were recruited into this meta-analysis from the databases of PubMed, Embase, Cochrane Library and CBM-disc (China Biological Medicine Database). Results were expressed with odds ratios (OR) for dichotomous data, and 95% confidence intervals (CI) were also calculated. Results: Eighteen investigations were identified for the analysis of association between polymorphic deletion of GSTT1 and HCC, consisting of 2,693 patients with HCC and 4,696 controls. Null genotype of GSTT1 was associated with HCC susceptibility in Chinese (OR=1.53, 95%CI: 1.28-1.82; P<0.00001). Conclusion: The GSTT1 null genotype is associated with HCC susceptibility in Chinese.

Aberrant Methylation of Genes in Sputum Samples as Diagnostic Biomarkers for Non-small Cell Lung Cancer: a Meta-analysis

  • Wang, Xu;Ling, Li;Su, Hong;Cheng, Jian;Jin, Liu
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권11호
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    • pp.4467-4474
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    • 2014
  • Background: We aimed to comprehensively review the evidence for using sputum DNA to detect non-small cell lung cancer (NSCLC). Materials and Methods: We searched PubMed, Science Direct, Web of Science, Chinese Biological Medicine (CBM), Chinese National Knowledge Infrastructure (CNKI), Wanfang, Vip Databases and Google Scholar from 2003 to 2013. The meta-analysis was carried out using a random-effect model with sensitivity, specificity, diagnostic odd ratios (DOR), summary receiver operating characteristic curves (ROC curves), area under the curve (AUC), and 95% confidence intervals (CI) as effect measurements. Results: There were twenty-two studies meeting the inclusion criteria for the meta-analysis. Combined sensitivity and specificity were 0.62 (95%CI: 0.59-0.65) and 0.73 (95%CI: 0.70-0.75), respectively. The DOR was 10.3 (95%CI: 5.88-18.1) and the AUC was 0.78. Conclusions: The overall accuracy of the test was currently not strong enough for the detection of NSCLC for clinical application. Dscovery and evaluation of additional biomarkers with improved sensitivity and specificity from studies rated high quality deserve further attention.

Efficacy of Chamomile in the Treatment of Premenstrual Syndrome: A Systematic Review

  • Khalesi, Zahra Bostani;Beiranvand, Soheila Pirdadeh;Bokaie, Mahshid
    • 대한약침학회지
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    • 제22권4호
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    • pp.204-209
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    • 2019
  • Premenstrual syndrome (PMS) encompasses a vast array of physical and psychological symptoms. Of the herbal supplements mentioned for remedy PMS symptoms, chamomile used as an effective herbal medicine. The overall purpose of this review was to determine the efficacy of chamomile on the treatment PMS. An extensive research review using Web of Science, the Cochrane Controlled Trials Register database, PubMed, Chinese Biomedical Database (CBM), CINAHL, China National Knowledge Infrastructure (CNKI), Psych INFO, Social Science Research Network, SID, Google Scholar, Iran Doc, Magiran and Iran Medex. Eligible studies were identified from English and Persian databases, published between 1990 and 2019. Studies were screened independently by two researchers who performed the data extraction. Of Twenty-seven studies identified, Eight RCTs met our inclusion criteria. Chamomile has been used to treat PMS relief because of therapeutic properties such as anti-inflammatory effects (Chamazulene and α-Bisabolol); anti-spasmodic effects (Apigenin, Quercetin, and Luteolin, Metoxicomarin, Matrisin, and Phytoestrogens); anti-anxiety effects (Glycine, Flavonoid). The results of this review show that Chamomile is effective for the treatment of PMS. Based on these results, we believe that Chamomile can be used as good herbal medicine to treat in women with PMS.

Lack of any Association between Insertion/Deletion (I/D) Polymorphisms in the Angiotensin-converting Enzyme Gene and Digestive System Cancer Risk: a Meta-analysis

  • Liu, Jin-Fei;Xie, Hao-Jun;Cheng, Tian-Ming
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권12호
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    • pp.7271-7275
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    • 2013
  • Objective: To investigate the association between the gene polymorphisms of angiotensin-converting enzyme (ACE) and digestive system cancer risk. Method: A search was performed in Pubmed, Medline, ISI Web of Science and Chinese Biomedical (CBM) databases, covering all studies until Sep 1st, 2013. Statistical analysis was performed by using Revman5.2 and STATA 12.0. Results: A total of 15 case-control studies comprising 2,390 digestive system cancer patients and 9,706 controls were identified. No significant association was found between the I/D polymorphism and digestive cancer risk (OR=0.93, 95%CI = (0.75, 1.16), P=0.53 for DD+DI vs. II). In the subgroup analysis by ethnicity and cancer type, no significant associations were found for the comparison of DD+DI vs. II. Results from other comparative genetic models also indicated a lack of associations between this polymorphism and digestive system cancer risks. Conclusions: This meta-analysis suggested that the ACE D/I polymorphism might not contribute to the risk of digestive system cancer.

Band Alignment at CdS/wide-band-gap Cu(In,Ga)Se2 Hetero-junction by using PES/IPES

  • Kong, Sok-Hyun;Kima, Kyung-Hwan
    • Transactions on Electrical and Electronic Materials
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    • 제6권5호
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    • pp.229-232
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    • 2005
  • Direct characterization of band alignment at chemical bath deposition $(CBD)-CdS/Cu_{0.93}(In_{1-x}Ga_x)Se_2$ has been carried out by photoemission spectroscopy (PES) and inverse photoemission spectroscopy (IPES). Ar ion beam etching at the condition of the low ion kinetic energy of 400 eV yields a removal of surface contamination as well as successful development of intrinsic feature of each layer and the interfaces. Especially interior regions of the wide gap CIGS layers with a band gap of $1.4\~1.6\;eV$ were successfully exposed. IPES spectra revealed that conduction band offset (CBO) at the interface region over the wide gap CIGS of x = 0.60 and 0.75 was negative, where the conduction band minimum of CdS was lower than that of CIGS. It was also observed that an energy spacing between conduction band minimum (CBM) of CdS layer and valance band maximum (VBM) of $Cu_{0.93}(In_{0.25}Ga_{0.75})Se_2$ layer at interface region was no wider than that of the interface over the $Cu_{0.93}(In_{0.60}Ga_{0.40})Se_2$ layer.

Thiadiazolopyrimidines as Acid Corrosion Inhibitors for Mild Steel

  • Chitra, S.;Parameswari, K.;Vidhya, M.;Kalishwari, M.;Selvaraj, A.
    • Corrosion Science and Technology
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    • 제10권1호
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    • pp.13-23
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    • 2011
  • The inhibitive action of thiadiazolopyrimidines on mild steel in 1 M $H_{2}SO_{4}$ has been studied using weight loss, gasometric studies and electrochemical polarization and AC impedance measurements. The effect of temperature on the corrosion behaviour of mild steel in 1 M $H_{2}SO_{4}$ with optimum concentration of inhibitors was studied in the temperature ranging from 313-333K The adsorption of the inhibitor on the surface of mild steel was found to be exothermic, spontaneous and followed the mechanism of physisorption. The adsorption of these compounds on mild steel surface was found to obey Langmuir adsorption isotherm. The protective film formed on the surface of mild steel by the adsorption of inhibitor in 1 M $H_{2}SO_{4}$ solution was confirmed by optical microscopic technique. Synergistic effect of halide ions on mild steel in 1 M $H_{2}SO_{4}$ was studied by weight loss technique.

Atmospheric Photochemistry in Low-and High-NOx Regimes

  • Kim, Do-Yong;Soda, Satoshi;Kendo, Akira;Oh, Jai-Ho
    • 한국환경과학회지
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    • 제16권1호
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    • pp.1-8
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    • 2007
  • Atmospheric photochemistry of $O_3-NOx-RH$ were considered theoretically, to clarify the reasons for the different trends of between the formation of photochemical oxidants (Ox) and its primary pollutants for the Low-and High-NOx regimes. Equations of OH, $HO_2$, and production of ozone ($O_3$) as a function of nitrogen oxides (NOx) and reactive hydrocarbons (RH) were represented in this study. For the Low-NOx regime, $HO_2$ radical is proportional to RH but independent of NOx. OH radical is proportional to NOx but inversely-proportional to RH. $O_3$ production is proportional to NOx but has a weak dependence on RH. For the High-NOx regime, OH and $HO_2$ radicals concentrations and $O_3$ production are proportional to RH but inversely-proportional to NOx. In addition, the Osaka Bay and surrounding areas of Japan were evaluated with the mass balance of odd-hydrogen radicals (Odd-H) using CBM-IV photochemical mechanism, in order to distinguish the Low- and High-NOx regimes. The Harima area (emission ratio, RH/NOx = 6.1) was classified to the Low-NOx regime. The Hanshin area (RH/NOx = 3.5) and Osaka area (RH/NOx = 4.3) were classified to the High-NOx regime.

Coal Bed Methane을 사용한 다양한 응용 기술에 대한 고찰 (A Study on Various Application Technologies Using Coal Bed Methane)

  • 조원준;이제설;유혜진;이현찬;주우성;임옥택
    • 한국수소및신에너지학회논문집
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    • 제29권1호
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    • pp.130-137
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    • 2018
  • Now discusses the potential use and applications of coal bed methane (CBM) in various industries. One of the options for gas monetization is gas to power (GTP), sometimes called gas to wire (GTW). Electric power can be an intermediate product, such as in the case of mineral refining in which electricity is used to refine bauxite into aluminum; or it can be an end product that is distributed into a large utility power grid. For stranded gas, away from the regional markets, the integration of the ammonia and urea plants makes commercial sense. These new applications, if established, could lead to a surge in demand for methanol plants.

No Association Between the GSTM1 Null Genotype and Risk of Renal Cell Carcinoma: A Meta-analysis

  • Liu, Rui;Wang, Xiao-Hua;Liu, Li;Zhou, Qiang
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권7호
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    • pp.3109-3112
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    • 2012
  • Background: Many studies have focused on possible associations between the glutathione S-transferase M 1 (GSTM1) null genotype and risk of renal cell carcinoma (RCC), but the impact remains unclear owing to obvious inconsistencies among the findings. The present study aimed to quantify the strength of any association in a meta-analysis. Methods: We searched the PubMed, Embase and CBM databases for studies concerning the association between the GSTM1 null genotype and risk of RCC. We estimated the summary odds ratio (OR) with its 95% confidence intervals (95% CI) to assess the association. Results: The meta-analysis showed the GSTM1 null genotype was not associated with risk of RCC overall (OR = 1.04, 95% CI 0.92-1.18, P = 0.501). For Caucasians, the GSTM1 null genotype was also not associated with risk of RCC (OR=1.02, 95% CI 0.90-1.16, P = 0.761). The cumulative meta-analyses showed a trend of no obvious association between GSTM1 null genotype and risk of RCC as information accumulated. Sensitivity analyses by omitting those studies also did not materially alter the overall combined ORs. No evidence of publication bias was observed. Conclusion: Meta-analyses of available data show that the GSTM1 null genotype is not significantly associated with risk of renal cell carcinoma.

Meta Analysis of Treatment for Stage IE~IIE Extranodal Natural Killer /T Cell Lymphomas in China

  • Li, Hui;Wang, Chun-Sen;Wang, Xiao-Dong
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권5호
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    • pp.2297-2302
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    • 2014
  • Objective: To evaluate early treatment for extranodal natural killer/T cell lymphoma (ENK/TCL) in China and provide reference for clinical treatment of these patients. Methods: Computer-based retrieval was performed in PubMed, CNKI, CBM, VIP and WanFang Data to search for randomized controlled trials (RCTs) of treatment for early ENK/TCL, and a meta-analysis was conducted with RevMan 5.0 software. Results: A total of 11 RCTs, including 871 patients, were selected, of which the first radiotherapy had a higher complete response (CR) than the first chemotherapy [OR=14.16, 95%CI (8.68, 23.10), P<0.00001] and CR was not different between combined treatment group and radiotherapy group [OR=1.86, 95%CI (0.47, 3.58), P=0.61], but long-term survival rate was higher with combined treatment[OR=1.88, 95%CI (1.09, 3.19), P=0.02]. No difference in survival rate was observed between radio-chemotherapy and chemo-radiotherapy groups [OR=1.11, 95%CI (0.73, 1.69), P=0.63]. Conclusions: Radiotherapy is of great significance in the treatment of early ENK/TCL, but combined therapy could further enhance long-term survival rate of patients. This conclusion still requires further confirmation using RCTs with high quality and large sample size.