• 제목/요약/키워드: CBE

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Buried-Ridge Waveguide Laser Diode 제작 및 특성평가 (Fabrication and characterization of InGaAsP/InP multi-quantum well buried-ridge waveguide laser diodes)

  • 오수환;이지면;김기수;이철욱;고현성;박상기
    • 한국광학회지
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    • 제14권6호
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    • pp.669-673
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    • 2003
  • 본 연구에서는 기존의 ridge waveguide laser diode(RWG LD)보다 ridge폭에 따른 측방향 단일모드 특성이 우수하고 planar 화에 유리하며 측방향의 유효 굴절률차를 ridge 구조에 추가로 성장된 InGaAsP층의 두께로 조절이 가능한 Buried RWG LD를제작하였다. 본 연구에서는 Buried RWG LD를 CBE장치로 InGaAs/InGaAsP multiple quantum well(MQW) 에피 웨이퍼를 성장하고, LPE로 재성장하여 B-RWG LD를 제작하였다. 또한 ridge 폭을 5 $\mu\textrm{m}$와 7 $\mu\textrm{m}$로 하여 B-RWG LD를 제작하고 특성을 비교하여 보았다. 제작된 7 $\mu\textrm{m}$ B-RWG LD에서 광출력이 20㎽에 이를 때까지 고차모드 발진에 의한 kink현상이 일어나지 않았으며, 포화 광출력이 80 ㎽ 이상임을 확인하였다. 제작된 B-RWG LD가 측방향 단일모드로 동작함을 확인하기 위해 FFP을 측정한 결과, ridge 폭이 5 $\mu\textrm{m}$일 때는 2.7I$_{th}$ , ridge 폭이 7 $\mu\textrm{m}$일 때는 2.4I$_{th}$ 까지 단일모드로 동작함을 확인할 수 있다.

RNase P-dependent Cleavage of Polycistronic mRNAs within Their Downstream Coding Regions in Escherichia coli

  • Lee, Jung-Min;Kim, Yool;Hong, Soon-Kang;Lee, Young-Hoon
    • Bulletin of the Korean Chemical Society
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    • 제29권6호
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    • pp.1137-1140
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    • 2008
  • M1 RNA, the catalytic subunit of Escherichia coli RNase P, is an essential ribozyme that processes the 5' leader sequence of tRNA precursors (ptRNAs). Using KS2003, an E. coli strain generating only low levels of M1 RNA, which showed growth defects, we examined whether M1 RNA is involved in polycistronic mRNA processing or degradation. Microarray analysis of total RNA from KS2003 revealed six polycistronic operon mRNAs (acpP-fabF, cysDNC, flgAMN, lepAB, phoPQ, and puuCBE) showing large differences in expression between the adjacent genes in the same mRNA transcript compared with the KS2001 wild type strain. Model substrates spanning an adjacent pair of genes for each polycistronic mRNA were tested for RNase P cleavage in vitro. Five model RNAs (cysNC, flgMN, lepAB, phoPQ, and puuBE) were cleaved by RNase P holoenzyme but not by M1 RNA alone. However, the cleavages occurred at non-ptRNA-like cleavage sites, with much less efficiency than the cleavage of ptRNA. Since cleavage products generated by RNase P from a polycistronic mRNA can have different in vivo stabilities, our results suggest that RNase P cleavage may lead to differential expression of each cistron.

Breast Cancer Knowledge and Screening Behavior among Female School Teachers in Gaza City

  • Abu-Shammala, Bissan Ismail;Abed, Yehia
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권17호
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    • pp.7707-7711
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    • 2015
  • A cross-sectional survey of 370 female teachers working at Governmental schools in Gaza city was conducted. Twenty four schools were selected randomly of all female schools of the city that included primary, preparatory and secondary. In each school all-female teachers aged 35-45 year were invited to fill out a self-administered questionnaire to investigate knowledge and behavior toward breast cancer screening. The survey revealed that more than 75% of women had never undergone clinical breast examination and 60% had never undergone mammography, whereas 62% performed breast self-examination (BSE). Women who performed BSE had significantly higher knowledge about breast cancer screening (P=0.001). Women attending CBE and mammography screening also had significantly higher knowledge (P=0.001). There were significant associations between the practices and presence of positive breast cancer family history (P=0.002) and the level of education of husbands (P=0.024). The oldest women demonstrated higher performance rates of screening methods than the youngest (P=0.001). Lack of breast screening knowledge was identified among more than one third of the women, and 24.6% of women did not know any screening method. About a half of women harboured misconceptions about breast cancer screening, including the belief that breast cancer not treatable. Women residing in Gaza city (P=0.00) and with husbands less educated were more likely to have a high level of misconceptions (P=0.01).

Breast Self-examination Practices and the Effect of a Planned Training Program in Western Turkey

  • Donmez, Yelda Candan;Dolgun, Eda;Yavuz, Meryem
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권12호
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    • pp.6159-6161
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    • 2012
  • This cross-sectional and descriptive study was aimed to evaluate women breast self-examination (BSE) practice and effects of a planned educational programme for breast cancer and BSE. The samples of the study consisted 266 women. The study data were collected by a questionnaire in six months periods as two times in a month in which the periods were defined and announced to all women. After that all the women were informed about BSE. The statue of performing BSE of women (n=146) was evaluated. They were interviewed on phone after 6 months. The collected data were analyzed by using statistical SPSS program. The average age of women was $35.68{\pm}7.54$. It is also determined that (61.3%) had no knowledge about BSE, (87.6%) had examined clinical breast examination (CBE) in a year and half of them (50.8%) never practiced BSE, (29.0%) had BSE regularly every month. Concerning the status of BSE practice before the education and after the education significant difference is found statistically (p<0.00). The significance of this study is that it is to give education about breast cancer and BSE for raising awareness among women.

Effect of a Training Programme on Knowledge of Nurses from a Missionary Hospital in India Regarding Breast Cancer and its Screening

  • Khokhar, Anita
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권12호
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    • pp.5985-5987
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    • 2012
  • A cross-sectional study was conducted among nursing staff of a missionary hospital of Delhi in June 2009. All the nurses were invited to participate in the training programme on breast cancer and techniques of breast self examination (BSE). A questionnaire was administered to all 259 participants seeking information on their level of awareness regarding breast cancer and relevant screening guidelines. With the help of 5 training workshops all the nurses were imparted training regarding the most appropriate technique of doing breast self exams. The mean age of the participants was 35.8 years. Out of a total of 259 nursing staff members 77.2% correctly answered all the 10 questions regarding high risk factors for breast cancer and after the training programme this increased to 100% (p<0.05). Only 65.2% of the participants gave correct responses to all the 8 questions regarding correct technique of performing a BSE, which after the training programme increased to 99.3% (p<0.05). At the baseline only 56.8% knew all the three screening methods correctly and after the intervention 98.7% could correctly mark the responses regarding screening (p<0.05). The actual practice of following the screening guidelines amongst the nursing staff was poor. Only 26 (10.03%) had ever done a BSE, none performed it monthly, 58 (22.4%) had ever gone themselves for a CBE and 18 (6. 94%) had ever undergone mammography.

Knowledge of Risk Factors & Early Detection Methods and Practices towards Breast Cancer among Nurses in Indira Gandhi Medical College, Shimla, Himachal Pradesh, India

  • Fotedar, Vikas;Seam, Rajeev K.;Gupta, Manoj K.;Gupta, Manish;Vats, Siddharth;Verma, Sunita
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권1호
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    • pp.117-120
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    • 2013
  • Background: Breast cancer is an increasing health problem in India. Screening for early detection should lead to a reduction in mortality from the disease. It is known that motivation by nurses influences uptake of screening methods by women. This study aimed to investigate knowledge of breast cancer risk factors & early detection methods and the practice of screening among nurses in Indira Gandhi Medical College, Shimla, Himachal Pradesh. Materials and Methods: A cross-sectional study was conducted using a self-administered questionnaire to assess the knowledge of breast cancer risk factors, early detection methods and practice of screening methods among 457 nurses working in a Indira Gandhi Medical College, Shimla-H.P. Chi square test, Data was analysed using SPSS version 16. Test of significance used was chi square test. Results: The response rate of the study was 94.9%. The average knowledge of risk factors about breast cancer of the entire population is 49%. 10.5% of nurses had poor knowledge, 25.2% of the nurses had good knowledge, 45% had very good knowledge and 16.3% of the nurses had excellent knowledge about risk factors of breast cancer and early detection methods. The knowledge level was significantly higher among BSC nurses than nurses with Diploma. 54% of participants in this study reportedly practice BSE at least once every year. Less than one-third reported that they had CBE within the past one year. 7% ever had mammogram before this study. Conclusions: Results from this study suggest the frequent continuing medical education programmes on breast cancer at institutional level is desirable.

미국 건축사시험 관리운영체제 연구 - ARE $4.0^{(R)}$ 버전을 중심으로 - (A Study on the Administration & Operating System of the Architect Registration $Examination^{(R)}$ in the USA - Focused on the Version of the ARE $4.0^{(R)}$ -)

  • 박종성
    • 한국디지털건축인테리어학회논문집
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    • 제11권2호
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    • pp.103-114
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    • 2011
  • The purpose of this study is to find good references for the administration & operating system of Korea Architects License Examination. It is because we may predict to discuss with its system to develop the international level. To achieve this goal, the 'Architect Registration $Examination^{(R)}$($ARE^{(R)}$)' in the USA was selected and analysed as one of the role models. As a result, the analysed key contents and study scopes are as below; 1) Consideration the evolutionary process to the administration & operating system of the Architect Registration $Examination^{(R)}$ in the USA 2) Working role the National Council of Architectural Registration Boards(NCARB) for the $ARE^{(R)}$ 3) Analysis the carrying out system of the cooperation network & infrastructure for the $ARE^{(R)}$ 4) Analysis the operating regulation & system of the newest version in the $ARE^{(R)}4.0$ 5) Consideration the administration & operating system's know-how of the Computer Based Examination in the $ARE^{(R)}$ 6) Research the taking exam.'s full process of the $ARE^{(R)}4.0$ from the beginning to the end 7) Comparative analysis between the Korea Architects License Examination and the $ARE^{(R)}4.0$.

Successful First Round Results of a Turkish Breast Cancer Screening Program with Mammography in Bahcesehir, Istanbul

  • Kayhan, Arda;Gurdal, Sibel Ozkan;Ozaydin, Nilufer;Cabioglu, Neslihan;Ozturk, Enis;Ozcinar, Beyza;Aribal, Erkin;Ozmen, Vahit
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권4호
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    • pp.1693-1697
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    • 2014
  • Background: The Bahcesehir Breast Cancer Screening Project is the first organized population based breast cancer mammographic screening project in Turkey. The objective of this prospective observational study was to demonstrate the feasibility of a screening program in a developing country and to determine the appropriate age (40 or 50 years old) to start with screening in Turkish women. Materials and Methods: Between January 2009 to December 2010, a total of 3,758 women aged 40-69 years were recruited in this prospective study. Screening was conducted biannually, and five rounds were planned. After clinical breast examination (CBE), two-view mammograms were obtained. True positivity, false positivity, positive predictive values (PPV) according to ACR, cancer detection rate, minimal cancer detection rate, axillary node positivity and recall rate were calculated. Breast ultrasound and biopsy were performed in suspicious cases. Results: Breast biopsy was performed in 55 patients, and 18 cancers were detected in the first round. The overall cancer detection rate was 4.8 per 1,000 women. Most of the screened women (54%) and detected cancers (56%) were in women aged 40-49. Ductal carcinoma in situ (DCIS) and stage I cancer and axillary node positivity rates were 22%, 61%, and 16.6%, respectively. The positive predictivity for biopsy was 32.7%, whereas the overall recall rate was 18.4 %. Conclusions: Preliminary results of the study suggest that population based organized screening are feasible and age of onset of mammographic screening should be 40 years in Turkey.

Relationships of Fear of Breast Cancer and Fatalism with Screening Behavior in Women Referred to Health Centers of Tabriz in Iran

  • Ghahramanian, Akram;Rahmani, Azad;Aghazadeh, Ahmad Mirza;Mehr, Lida Emami
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권9호
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    • pp.4427-4432
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    • 2016
  • Background: Fear and fatalism have been proposed as factors affecting breast cancer screening, but the evidence is not strong. This study aimed to determine relationships of fear and fatalism with breast cancer screening behavior among Tabriz women in Iran. Materials and Methods: In a cross- sectional study, 370 women referred to 12 health centers in Tabriz were selected with two-stage cluster sampling and data regarding breast cancer screening, fatalism and fear of breast cancer were collected respectively with a checklist for screening performance, Champions Fear and Pow Fatalism Questionnaires. Data were analyzed by logistic regression with SPSS software version 16. Results: Only 43% and 23% of participants had undergone breast self- examination and clinical breast examination. Among women older than 40 years, 38.2% had mammography history and only 2.7% of them had done it annually. Although fatalism and fear had a stimulating effects on breast cancer screening performance th relationships were not significant (P>0.05). There was a negative significant correlation between fear and fatalism (r= -0.24, p=0.000). On logistic regression analysis, age (OR=1.037, p<0.01) and income status (OR= 0.411, p<0.05) significantly explained BSE and age (OR=1.051, p<0.01) and body mass index (OR= 0.879, p<0.01) explained CBE. Also BMI (OR= 0.074, p<0.05) and income status (OR=0.155, p<0.01) was significantly effective for mammography following. Conclusions: Breast cancer screening behavior is inappropriate and affected by family livelihood status and lifestyle leads to weight gain, so that for promoting of screening behaviors, economic support to families, lifestyle modification and public education are suggested.

Fe ion을 주입한 1.55$\mu\textrm{m}$ MQW 레이저 다이오드의 전기적 절연 특성

  • 강병권;김태곤;박윤호;우덕하;이석;김선호;강광남;송종한;황정남;박승한
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 1999년도 제17회 학술발표회 논문개요집
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    • pp.91-91
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    • 1999
  • 광소자 기술은 정보 전달 및 저장 기술의 지속적인 증가 요구에 따라 발전을 거듭하여 왔다. 특히 광통신 및 저장 기술에서 광원으로 사용되는 레이저 다이오드는 안정되면서 쉽게 제작할 수 있어야 한다. 이온 주입 방법은 반도체 공정에서 광범위하게 사용되는 공정이며 이미 소자측면에서 안정성이 확보되었다고 볼 수 있으나 대부분 메모리 등의 실리콘 반도체에서 이용되어 왔다. 최근에는 화합물 반도체 분야에서도 적용하는 예가 증가되고 있으나 광원으로 사용되는 레이저 다이오드의 경우는 우수한 품질의 반도체 층이 요구되며 따라서 damage가 큰 이온 주입 방법을 이용한 연구는 아직 많이 이루어져 있지 않다. 본 연구에서는 레이저 다이오드 구조의 성장측에 국부적으로 Fe 이온을 주입하여 도파로를 형성하여 광을 구속하여 도파시키는 동시에 전기적으로도 도파로 부분으로만 다이오드가 형성되도록 하고자 한다. 먼저 p층의 전기적 절연에 필요한 조건을 확보하기 위하여 CBE를 사용하여 Fe가 doping 된 SI-InP wafer 위에 p-InP (Be:5x1017 cm-3)층을 1.2$mu extrm{m}$ 성장한 후 ohmic 층으로 p-InGaAs (Be:1x1019 cm-3)을 0.1$\mu\textrm{m}$ 성장한 시료에 고에너지 이온 주입 장치를 사용하여 Fe 이온을 1MeV, 1.6meV의 에너지에 각각 1x1014cm-2, 2x1014cm-2 의 dose로 전면에 implant 하였다. 이 시료를 tube furnace에서 500, 600, $700^{\circ}C$각각 10분씩 annealing 한 후 재성장을 확인하기 위하여 DCXRD을 측정하였다. 그림 1은 DCXRD rocking curve로 annealing 하기 전 후의 In rich에서 side peak의 감소를 확인 할 수 있었는데 이는 damage가 어느 정도 복구되었음을 의미한다. 또한 절연 특성을 확인하기 위하여 ohmic metal을 증착하여 Hall 효과를 측정하였다. 그림 2에 보이는 것과 같이 annealing 온도가 증가함에 따라 면저항이 크게 증가함을 볼 수 있으며 이온 주입하기 전의 시료에 비해 104 이상의 저항을 갖을 수 있다. 향후 이러한 결과를 바탕으로 1.55$\mu\textrm{m}$ LD 구조에서 발진 특성을 관찰할 계획이다.

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