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Development of Student-oriented Reformation for Pharmacy Education (수요자중심의 약학교육 개선 방향에 관한 연구)

  • 김태두;김창종
    • Proceedings of the PSK Conference
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    • 1999.06a
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    • pp.30-60
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    • 1999
  • In spite of many studies of The Korean Association of College of Pharmacy for improvement of the Korean pharmacy education and decrearing to change 4 year curriculum for pharmacy education to 6year curriculum from 1998 by The Ministry of Health and Wellfaire, there are many problems right now in view of the student-oriented education in front of the revolution program of The Ministry of Education. So the student-oriented reformation for pharmacy education in Korea was studied not only by observations of worldwide pharmacy education and pharmacy system, but also by 416 questionaires from many kinds of man and women such as pharmacists in drug store and hospital(159), administraters of The Ministry of Health and Wellfaire (59), professors in college of pharmacy (65), researchers in pharmaceutical company (31) and seniors in college of pharmacy(102).It shows that our Korean pharmacy education was a type of teacher-oriented education which is caused by the short time-education, a lots of subjects in the examination for pharmacy license and egoism of professors for their subjects, and so our teacher-oriented education have to change to the student-oriented education for the most function of pharmacist which is the pharmaceutical care for patients. For the preparing the clerkship/externship for one year, we have to change 4 year curriculum to 6 year curriculum for clinical pharmacy edu-cation, and also subjects of pharmacy in the national examination for pharmacy liciense have to reduce within 3-4 subjects of totally non-subject examination. The Korean Association of Collage of Pharmacy of Pan-pharmaceutical Revolution Association must purchase them and their program can be begun right now in spite of loss of the pharmacist supplement for 2 year and preparing the program of 6 years curriculum. Our teaching purposes of departments of pharmacy and manufacturing pharmacy were respectively clinical pharmacy, and development of new drug and compounding of many kinds of commercial drugs, but we have been not gone to their goals, respectively, because of short time-education for pharmacy as compared as world-wide pharmacy education containing the clerkship/externship and same twelve subjects in their examination for pharmacy license. Most function of pharmacist in Korea are the development of new drug, and social and administrative pharmacy in health care for patients, and so we have to teach them in the department of maunfacturing pharmacy.

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Studies on the Heavy Metals in Paddy Rice and Soils in Jang-hang Smelter (제연소인근지역(製鍊所隣近地域)의 토양(土壤) 및 수도체중(水稻體中) 중금속함량(重金屬含量)에 관(關)한 조사연구(調査硏究))

  • Kim, Seong-Jo;Ryang, Hwan-Seung
    • Korean Journal of Soil Science and Fertilizer
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    • v.18 no.4
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    • pp.336-347
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    • 1985
  • Soils and rice plants subject to smoke from the Jang-hang Smelter were samples at two depths to assess the nature and extend of Cd, Cu, Pb, and Zn contamination, particularly with respect to distance from pollution source. Soils at east site within 1km of the center of the smelter were highly contaminated with Cd, Cu, Pb, and Zn. Metal levels in the smoke-polluted area were higher in surface soil than in subsurface soil, and decreased rapidly with distance reaching nearly background levels at 5km from pollution source. A position correlation was found between contents of total and 0.1 N HCl-extractable, or 1.0N $CH_3COONH_4$- extractable heavy metals in surface soils of pollution. Contents of heavy metals in soils were positively correlated with soil organic matter and cation exchange capacity. The contents of heavy metals in brown rice collected from the paddy field around the Jang-hang Smelter were in the range of 0.23-1.33 ppm for Cd, 2.39-6.25 for Cu, 0.95-8.32 ppm for Pb and 14.60-27.31 for Zn. The contents of Cd, Cu, and Zn in rice straw were positively correlated with those in the brown rice. Negative correlation was found between the contents of Cd, Cu, Pb, and Zn in brown rice and the distance from the source.

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The Soil Improvement and Plant Growth on the Newly-Reclaimed Sloped Land -I. Effects of Vinyl Mulching and Zeolite Application on Silage Corn (신개간경사지(新開墾傾斜地) 토양개량(土壤改良)과 작물생육(作物生育)에 관(關)한 연구(硏究) -I. 청예용(靑刈用) 옥수수에 대(對)한 비닐피복(被覆) 및 Zeolite 시용(施用) 효과(效果))

  • Hur, Bong-Koo;Jo, In-Sang;Um, Ki-Tae
    • Korean Journal of Soil Science and Fertilizer
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    • v.22 no.1
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    • pp.25-30
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    • 1989
  • A field experiment was carried out to evaluate the effects of zeolite application and vinyl mulching on the changes in soil physico-chemical properties and yield of silage corn on the newly-reclaimed sloped land. Corn (Suweon 19) was cultivated under 4 application levels of zeolite, 0, 500, 1,000 and 1,500 kg/10a, with and without vinyl mulching, and various soil physico-chemical properties and corn growth were investigated. Soil physical properties, such as cation exchange capacity and water stable aggregates, were increased, but soil hardness was decreased by zeolite application. The porosity and temperature of soil were increased greatly by vinyl mulching. The differences between daily maximum and minimum soil temperature were large in beginning stages of crop growth, but those were decreased to $2^{\circ}C$ after mid-August. Zeolite application enhanced the plant growth and increased yields by 3-37% compare to control, also vinyl mulching brought to increase the corn yields by 17-23%. Water stable aggregates was correlated with soil hardness, and silage yields were highly correlated with porosity, air phase and water stable aggregates.

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Granulation of Artificial Zeolite for the Simultaneous Removal of Nitrogen and Phosphorous from the Wastewater (질소, 인 동시 제거용 입상 인공제올라이트 제조)

  • Lee, Deog-Bae;Lee, Kyeong-Bo;Han, Sang-Soo;Henmi, Teruo
    • Korean Journal of Soil Science and Fertilizer
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    • v.31 no.1
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    • pp.67-71
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    • 1998
  • This study was carried out to granulate artificial zeolite powder that remove ammonium nitrogen and phosphorous simultaneously in wastewater treatment. Optimum water content was required for 30 percent volume to granulate artificial zeolite with 1.7mm diameter and 1~2cm length using granulator. Portland cement could remove much $NH_4{^+}$ and $PO_4{^{3-}}$ from the wastewater than other binding materials. Mixed 33, 25. 20. 16 percent of portland cement to artificial zeolite powder(v/v), cation exchange capacity of the granulars were 66.5, 81.4, 126.8, $151.2cmol^+kg^{-1}$ and hardness of that were 176.1, 24.4, 4.1, $0.4kg\;cm^{-2}$, respectively. Content of portland cement in the granular were related with removal of $PO_4{^{3-}}$ positively and that of $NH_4{^+}$ negatively. Shaked 1g of the granulars that made of portland cement 33 percent with 40ml synthetic wastewater containing $NH_4{^+}$ $1545mgl^{-1}$ and $PO_4{^{3-}}$ $417mgl^{-1}$, 99.4 percent of $NH_4{^+}$ and 90.3 percent of $PO_4{^{3-}}$ were removed simultaneously after 48 hours shaking. The longer shaking, the more $NH_4{^+}$ and $PO_4{^{3-}}$were removed. The artificial zeolite granular had both micropore and macropore that could be useful in the wastewater purification.

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Relative Contribution rate on Soil Physico-chemical properties Related to Fruit Quality of 'Fuji' apple (사과 '후지' 품종의 품질에 미치는 토양이화학성의 상대적 기여도)

  • Kim, Seung-Heui;Choi, In-Myung;Han, Jeom-Wha;Cho, Jung-Gun;Son, In-Chang;Lim, Tae-Jun;Yun, Hea-Keun
    • Korean Journal of Soil Science and Fertilizer
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    • v.44 no.5
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    • pp.722-726
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    • 2011
  • The management standard on soil conditions in 'Fuji' apple to produce high quality fruit were not yet made. Therefore, this study was carried out to investigate the optimum soil environmental conditions of ten contents on production of high quality fruit in 'Fuji' apple. The soil and fruit characteristics were analyzed at total 60 orchards in major apple producing areas such as Chungju, Moonkyeung, yeongju, andong, yeosan and yeongcheon (10 orchards an area). The soil environmental factors affected fruit weight was highest relative contribution in saturated hydraulic conductivity of 36.5%. The bulk density and soil pH were low as relative contribution. The fruit weight was influenced by soil physical properties more than soil chemical properties. The soil environmental factors affected sugar content were hydraulic conductivity of 28.3% and organic matter content of 18.2%. The cultivation layer depth and soil pH were low as relative contribution. The fruit coloring was highest relative contribution in saturated hydraulic conductivity 55.9%. while soil pH, cation and soil texture were low. Fruit coloring was high influenced over 70% by soil physical properties. Finally, relative contribution on fruit quality related with sugar content, fruit weight, and coloring were high influenced by saturated hydraulic conductivity of 21.% and organic matter content of 18.7% but bulk density and cultivation layer depth were low relative contribution. The fruit growth and saturated hydraulic conductivity in 'Fuji' apple were very closely related. Therefore, orchard soil management to produce high quality fruit was very importance drainage management and organic matter application. We concluded that scientific soil management is possible by qualifiable of soil management factors.

Effects of Rice Straw Incorporation by Cutting Methods on Soil Properties and Rice Yield in a Paddy Field (볏짚 혼입이 논 토양개선 및 쌀수량에 미치는 영향)

  • Yang, Chang-Hyu;Kim, Taek-Kyum;Ryu, Jin-Hee;Lee, Sang-Bog;Kim, Sun;Baek, Nam-Hyun;Choi, Weon-Young;Chung, Doug-Young;Kim, Si-Ju
    • Korean Journal of Soil Science and Fertilizer
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    • v.43 no.6
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    • pp.1047-1050
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    • 2010
  • This study was to investigate the effects of rice straw incorporation by cutting height on paddy soil fertility. The average residual amount of rice straw by cutting height were showed 1,420 kg $ha^{-1}$, 1,850 kg $ha^{-1}$, and 2,400 kg $ha^{-1}$ for depths of 10 cm, 15 cm, and 20 cm, respectively. For soil physical properties, soil hardness and bulk density were decreased while porosity was increased by rice straw incorporation. But soil organic matter (SOM), available silicate content, and cation exchange capacity (CEC) were significantly decreased when rice straw was removed from the field. These results indicated that the SOM as residual amount of rice straw was influenced by level of cutting height. Milled rice yield was increased by 28% and 32% for cutting heights of 15 cm and 20 cm, compared with that of control, respectively. The number of spikelets per square meter and the percentage of ripeness were increased with increasing incorporation by lower level of cutting height of rice straw. Therefore, incorporation of rice straw practices under cutting method influenced soil improvement and rice yield in paddy field.

Isolation and purification of a cecropin-like antimicrobial peptide from the japanese oak silkworm, Antheraea yamamai (천잠 세크로핀 항균펩타이드 분리 및 정제)

  • Kim, Seong-Ryul;Goo, Tae-Won;Choi, Kwang-Ho;Park, Seung-Won;Kim, Sung-Wan;Hwang, Jae-Sam;Kang, Seok-Woo
    • Journal of Sericultural and Entomological Science
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    • v.50 no.2
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    • pp.145-149
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    • 2012
  • Cecropin is a well-studied antimicrobial peptide that play important role as key factor in insect humoral immunity. In this study, cecropin-like antimicrobial peptide was isolated and purified from the larval haemolymph of immune-challenged japanese oak silkworm, Antheraea yamamai. To isolate antimicrobial peptide, we separated and compared acidic extracted hemolymph protein bends between control and immune-challenged larvae using SDS-PAGE analysis. In the immune hemolymph extract, but not of non-immune hemolymph, we detected differential expressed peptide band with molecular mass 4,223.01 Da. To understand this peptide better, we successfully purified this peptide using cation exchange chromatography and gel permeation chromatography. Its N-terminal amino acid sequence obtained by Edman degradation evidenced a significant degree of identity with other lepidopteran cecropins. The purified A. yamamai cecropin-like peptide showed a broad spectrum of activity against fungi, Gram-negative and Gram-positive bacteria.

Physico-Chemical Properties of Paddy Soil and Actual Farming Conditions in Gyehwa Reclaimed Tidal Land (계화간척지 논토양의 물리화학적 특성 및 영농실태)

  • Yoo, Chul-Hyun;Yang, Chang-Hyu;Kim, Taek-Kyum;Ryu, Jin-Hee;Jung, Ji-Ho;Kang, Seung-Weon;Kim, Jae-Duk;Jung, Kwang-Yung
    • Korean Journal of Soil Science and Fertilizer
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    • v.40 no.2
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    • pp.109-113
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    • 2007
  • In order to establish the fertilization and soil management method in Gyehwa reclaimed tidal land, we investigated soil property and actual farming condition. Soil properties of 100 field paddy soil and farming surveys of 177 farm households were conducted. Average of effective soil depth was 17.8 cm, which was very smaller than the optimum level 50 cm. The hardness and bulk density of subsoil were $12.40kg\;cm^{-2}$ and $1.59g\;cm^{-3}$, respectively. These results showed that soil physical condition of Gyehwa reclaimed tidal land was very poor. Soil salinity ranged from 0.03 to 0.12%, and average of pH was 6.0, which implied that desalinization of Gyehwa reclaimed tidal land was progressed. However, soil nutrients in Gyehwa reclaimed tidal land were very unbalanced conditions as following, available phosphate $58mg\;kg^{-1}$, available silicate $85mg\;kg^{-1}$, cation exchangeable capacity $7.4cmolc\;kg^{-1}$ and organic matter $8.6g\;kg^{-1}$. On the farm household in Gyehwa reclaimed tidal land, fertilization amounts were $200-54-61(N-P_2O_5-K_2O)kg\;ha^{-1}$ They mainly practiced spring tillage(84%) rather than autumn tillage(16%), and only 14% of them applied rice straw annually in the paddy soil.

Characteristic of Precipitated Metal Carbonate for Carbon Dioxide Conversion Using Various Concentrations of Simulated Seawater Solution (해수 농축수 내 금속 이온 농도에 따른 이산화탄소 전환 생성물의 특성연구)

  • Choi, Eunji;Kang, Dongwoo;Yoo, Yunsung;Park, Jinwon;Huh, Il-sang
    • Korean Chemical Engineering Research
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    • v.57 no.4
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    • pp.539-546
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    • 2019
  • Global warming has mentioned as one of the international problems and these researches have conducted. Carbon Capture, Utilization and Storage (CCUS) technology has improved due to increasing importance of reducing emission of carbon dioxide. Among of various CCUS technologies, mineral carbonation can converted $CO_2$ into high-cost materials with low energy. Existing researches has been used ions extracted solid wastes for mineral carbonation but the procedure is complicated. However, the procedure using seawater is simple because it contained high concentration of metal cation. This research is a basic study using seawater-based wastewater for mineral carbonation. 3 M Monoethanolamine (MEA) was used as $CO_2$ absorbent. Making various concentrations of seawater solution, simulated seawater powder was used. Precipitated metal carbonate salts were produced by mixing seawater solutions and $rich-CO_2$ absorbent solution. They were analyzed by X-ray Diffraction (XRD), Scanning Electron Microscope (SEM), and Thermogravimetric Analysis (TGA) and studied characteristic of producing precipitated metal carbonate and possibility of reusing absorbent.

Purification of Alginate Lyase from Streptomyces violaceoruber and the Growth Activity of Intestinal Bacteria by Degree of Polymerization of Alginate Hydrolysates (Streptomyces violaceoruber 유래 Alginate Lyase의 정제 및 Sodium Alginate 가수분해 올리고당의 중합도별 Bifidobacterium spp.과 Lactobacillus spp.에 대한 생육활성)

  • Yoon, Min;Park, Young-Seo;Park, Gwi-Gun
    • Food Engineering Progress
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    • v.21 no.2
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    • pp.103-109
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    • 2017
  • Alginate lyase from Streptomyces violaceoruber was purified by DEAE sephacel chromatography and SP sepharose chromatography. The specific activity of the purified enzyme was 14.6 units/mg protein, representing a 40.6-fold purification of the crude extract. The final preparation thus obtained showed a single band on Tricine-SDS polyacrylamide gel electrophoresis whose molecular weight was determined to be 23.3 kDa. The polyMG block of sodium alginate was hydrolyzed by the purified alginate lyase and then separated by activated carbon column chromatography and bio gel P-2 gel filtration. The main hydrolysates were composed of hetero type M/G-oligosaccharides with the degrees of polymerization (D.P.) being 6 and 8. To investigate the effects of hetero type M/G-oligosaccharides from the sodium alginate on the growth of some intestinal bacteria, cells were cultivated individually on the modified-MRS medium containing D.P. 6 and 8 M/G-oligosaccharides. B. longumgrew 4.25-fold and 6.44-fold more effectively by the treatment of D.P. 6 and 8 M/G-oligosaccharides compared with those of standard MRS medium. In addition, B. bifidumgrew 3.3-fold and 5.4-fold more effectively by the treatment of D.P. 6 and 8 M/G-oligosaccharides. In conclusion, D.P. 8 was more effective than D.P. 6 hetero M/G-oligosaccharides as regards the growth of Bifidobacteriumspp. and Lactobacillus spp.