• Clinical and Experimental Pediatrics
• /
• v.63 no.12
• /
• pp.485-490
• /
• 2020

Background: Recurrent abdominal pain (RAP) is one of the frequent complaints in general practice, particularly in pediatrics and is among the common cause of referral to gastroenterology clinics. Purpose: This study is designed to investigate the effects of probiotics for the treatment of RAP and desired therapeutic outcomes. Methods: One hundred twenty-five children with the diagnosis of RAP according to Rome III criteria for irritable bowel syndrome (IBS), functional abdominal pain (FAP), functional dyspepsia (FD), and abdominal migraine (AM), were enrolled in this double-blind randomized controlled trial. Results: Sixty-five subjects received probiotics, and others received placebo treatment for 4 weeks. Lactobacillus reuteri was therapeutically effective in 32 patients compared to 8 patients, responding to the placebo treatment. Compared to baseline, all pain-related variables showed a significant reduction for the IBS and FD at the end of the 4th week. However, it did not respond well in FAP and AM groups. Pain-related outcomes such as, frequency of the pain, severity, and duration of the pain were decreased following the probiotic treatment. No therapeutic response was seen in AM group after the administration of probiotics. L. reuteri significantly led to pain relief in the overall population, and also in FAP, FD, and IBS subgroups. Conclusion: L. reuteri probiotics are likely to lead to RAP relief and can be recommended for the treatment of functional gastrointestinal disorders.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.15 no.5
• /
• pp.1649-1665
• /
• 2021

In view of the low accuracy of the traditional FunkSVD algorithm, and in order to improve the computational efficiency of the algorithm, this paper proposes a parallel algorithm of improved FunkSVD based on Spark (SP-FD). Using RMSProp algorithm to improve the traditional FunkSVD algorithm. The improved FunkSVD algorithm can not only solve the problem of decreased accuracy caused by iterative oscillations but also alleviate the impact of data sparseness on the accuracy of the algorithm, thereby achieving the effect of improving the accuracy of the algorithm. And using the Spark big data computing framework to realize the parallelization of the improved algorithm, to use RDD for iterative calculation, and to store calculation data in the iterative process in distributed memory to speed up the iteration. The Cartesian product operation in the improved FunkSVD algorithm is divided into blocks to realize parallel calculation, thereby improving the calculation speed of the algorithm. Experiments on three standard data sets in terms of accuracy, execution time, and speedup show that the SP-FD algorithm not only improves the recommendation accuracy, shortens the calculation interval compared to the traditional FunkSVD and several other algorithms but also shows good parallel performance in a cluster environment with multiple nodes. The analysis of experimental results shows that the SP-FD algorithm improves the accuracy and parallel computing capability of the algorithm, which is better than the traditional FunkSVD algorithm.

• The Journal of Asian Finance, Economics and Business
• /
• v.9 no.9
• /
• pp.229-239
• /
• 2022

The primary objective of the current study is to ascertain the effect of transparency and disclosure (T&D) on the value of banks operating in the Indian banking sector. It also includes finding the moderating impact of financial distress (FD) and environmental, social, and governance (ESG) on the association between T&D and the valuation of banks. The study employs Panel data analysis (PDA) to analyze data and produce novel results thereafter. The authors of the study have considered using data of secondary nature which is sourced from banks operating in the Indian banking industry. Data in the current study has been considered for ten financial years, i.e., 2010 to 2019. The results reveal that T&D positively impacts a firm's valuation. We have also found evidence that financial distress and ESG (Environmental, Social, and Governance) significantly impact the value of firms under the influence of T&D. As far as we are aware, no study of this kind has been done yet in any developing nation to determine the effect that T&D, FD, and ESG have on the value of Indian banks. This paper can help future researchers in their respective studies that will involve the study variables (FD, T&D, and ESG).

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.15 no.7
• /
• pp.4416-4422
• /
• 2014

In the present study, mycosporine-like amino acids (MAAs)were extracted from in Chlamydomonas hedleyi, and their function was investigated regarding to protective capacity against UV radiation and a possibility to be developed into functional suncream including MAAs by using natural compounds. In particulr, we assessed UV protective ability and anti-inflammation of shinorine in human skin cells. As a result, shinorine can protect the skin against damage by the absorption of energy from UV radiation and functions as an anti-wrinkling substrate through a increase of collagen synthesis. These data suggest that shinorine can be utilized not only as a substrate to protect UV radiation, but anti-aging material in cosmetic products.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.15 no.9
• /
• pp.5628-5636
• /
• 2014

Currently, many countries have an interest in developing cosmetics materials using native plants. In this aspect, there is increasing need to develop cosmetics materials using native plants in our county. In the present study, calluses were induced from Artemisia annua Linne, which was highlighted because of its useful effects, such as anti-cancer, anti-fungal and anti-inflammation. Water and ethanol extractions were performed from the calluses of Artemisia annua Linne. After the mass production of Artemisia annua Linne's calluses, water and ethanol extraction was performed to examine its functional roles in healing wounds and inflammation. The differences in the effective elements were observed in the ethanol extract. The callus showed anti-inflammation activity through the suppression of the inflammation-related gene, COX-2, and ethanol extracts showed their ability to heal wounds. Overall, these results suggest that the extract of Artemisia annua Linne's calluses is a natural and environment-friendly material, and can be used as medical supplies associated with anti-inflammation and healing wounds.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.15 no.8
• /
• pp.5070-5077
• /
• 2014

Many countries in the world have protected their native plants and utilized them as industrial materials in each country. In this aspect, it is increasingly important to develop cosmetics materials using native plants in Korea. Cosmetic materials have been developed with niche plants, such as Campanula takesimana Nakai, Dianthus superbus, Aster spathulifolius in Ullengdo, in which a specific plant distribution by distinct climate and environment was present. Water and ethanol extractions were performed from the calluses of Campanula takesimana Nakai, Dianthus superbus, Aster spathulifolius. HPLC analysis revealed different compositions and functions of effective elements in each ethanol extract. For example, all types of ethanol extracts showed an ability to heal wounds. In particular, the expression of the inflammation-related gene, COX-2, was decreased in response to the ethanol extracts of Dianthus superbus. These results indicate that the ethanol extracts from niche plants' calluses in Ullengdo are natural and environmentally-friendly compounds, and can be used as medical supplies associated with anti-inflammation and wound healing.

• Food Science of Animal Resources
• /
• v.40 no.5
• /
• pp.795-812
• /
• 2020

Novel food sources have enormous potential as nutritional supplements. For instance, edible insects are considered as an alternative food source due to their higher protein content; moreover, they are economically efficient reproducers and have high in nutritional value. In this study, we investigated the toxicity of the freeze-dried powder of Locusta migratoria (fdLM), known to contain rich proteins as well as fatty acids. The objective of the present study was to evaluate the subacute toxicity of fdLM in male and female Sprague-Dawley (SD) rats. The SD rats were divided into four groups based on the dosage of fdLM administered: dosage of 0 (vehicle control), 750, 1,500, and 3,000 mg/kg/day were administered for 28 days. Toxicological assessments including observations on food consumption, body and organ weights, clinical signs, mortality, ophthalmologic tests, urinalyses, hematologic tests, clinical chemistry tests, gross findings, and histopathology tests were performed. Clinical signs, urinalyses, hematology, serum biochemistry tests, and organ weight examinations revealed no fdLM-related toxicity. The no-observed-adverse-effect level for fdLM was higher than 3,000 mg/kg/day in rats of both sexes; therefore, fdLM, in conclusion, can be considered safe as an edible alternative human and animal food source material.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
• /
• v.38 no.2
• /
• pp.109-121
• /
• 2020

Depth calculation of objects in a scene from images is one of the most studied processes in the fields of image processing, computer vision, and photogrammetry. Conventionally, depth is calculated using a pair of overlapped images captured at different view points. However, there have been studies to calculate depths from a single image. Theoretically, it is known to be possible to calculate depth using the diameter of CoC (Circle of Confusion) caused by defocus under the assumption of a thin lens model. Thus, this study aims to verify the validity of the thin lens model to calculate depth from edge blur amount which corresponds to the radius of CoC. For this study, a commercially available DSLR (Digital Single Lens Reflex) camera was used to capture a set of target sheets which had different edge contrasts. In order to find out the pattern of the variations of edge blur against varying combination of FD (Focusing Distance) and OD (Object Distance), the camera was set to varying FD and target sheet images were captured at varying OD under each FD. Then, the edge blur and edge displacement were estimated from edge slope profiles using a brute-force method. The experimental results show that the pattern of the variations of edge blur observed in the target images was apart from their corresponding theoretical amounts derived under the thin lens assumption but can still be utilized to calculate depth from a single image for the cases similar to the limited conditions experimented under which the tendency between FD and OD is manifest.

• Journal of Oriental Medical Thermology
• /
• v.6 no.1
• /
• pp.56-62
• /
• 2008

Objective: To investigate the significance of temperature differences on two different acupuncture points between functional dyspepsia(FD) group and non-functional dyspepsia(non-FD) group respectively. Methods: We performed this research on 40 patients who came and took D.I.T.I in Kang-nam korean hospital kyung-hee university. We analyzed the averaged temperature of Zhongwon(CV12), Indang(HN1) and, also, investigated the significance of subtraction from Indang to Zhongwon temperature statistically. Results: The temperature differences from Indang to Zhongwon between functional dyspepsia group and non-functional dyspepsia group was significant, it meant that patients who have functional dyspepsia have more significant temperature difference from Indang(HN1) to Zhongwon(CV12). The direct comparisons of mean temperature between Indang and Zhongwon in the FD group and non-FD group were not significant. Conclusion: The study provide hypothesis on the temperature difference from Indang(HN1) to Zhongwon(CV12) and its association with functional dyspepsia. This study can provide a foundation for future studies on the evaluation of functional dyspepsia by using D.I.T.I.

• Aerospace Engineering and Technology
• /
• v.11 no.1
• /
• pp.103-110
• /
• 2012

In the COMS satellite mission operation, more large meteorological images such as Full Disk(FD) image or 2 adjacent Extended Northern Hemisphere(ENH) images can be taken by the time shift of East West Station Keeping(EWSK) maneuver when the EWSK conflicts with the large images. In this study an analytical approach based on probability of the conflict is proposed for theoretical analysis about the EWSK time shift to avoid the conflict with FD or 2 ENH images. The EWSK time shift has been applied to the COMS operation as a test, too. The theoretical study result and test operation outcome are synthesized to provide the analysis of impact on the COMS fuel consumption by the EWSK time shift. This study is expected to contribute to the maximization of COMS meteorological mission application.