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Effects of Ag and Cu Additions on the Electrochemical Migration Susceptibility of Pb-free Solders in Na2SO4 Solution

  • Yoo, Y.R.;Nam, H.S.;Jung, J.Y.;Lee, S.B.;Park, Y.B.;Joo, Y.C.;Kim, Y.S.
    • Corrosion Science and Technology
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    • v.6 no.2
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    • pp.50-55
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    • 2007
  • The smaller size and higher integration of advanced electronic package systems result in severe electrochemical reliability issues in microelectronic packaging due to higher electric field under high temperature and humidity conditions. Under these harsh conditions, electronic components respond to applied voltages by electrochemical ionization of metal and the formation of a filament, which leads to short-circuit failure of an electronic component, which is termed electrochemical migration. This work aims to evaluate electrochemical migration susceptibility of the pure Sn, Sn-3.5Ag, Sn-3.0Ag-0.5Cu solder alloys in $Na_{2}SO_{4}$. The water drop test was performed to understand the failure mechanism in a pad patterned solder alloy. The polarization test and anodic dissolution test were performed, and ionic species and concentration were analyzed. Ag and Cu additions increased the time to failure of Pb-free solder in 0.001 wt% $Na_{2}SO_{4}$ solution at room temperature and the dendrite was mainly composed of Sn regardless of the solders. In the case of SnAg solders, when Ag and Cu added to the solders, Ag and Cu improved the passivation behavior and pitting corrosion resistance and formed inert intermetallic compounds and thus the dissolution of Ag and Cu was suppressed; only Sn was dissolved. If ionic species is mainly Sn ion, dissolution content than cathodic deposition efficiency will affect the composition of the dendrite. Therefore, Ag and Cu additions improve the electrochemical migration resistance of SnAg and SnAgCu solders.

Development and Assessment of New RT-qPCR Assay for Detection of HIV-1 Subtypes

  • Lim, Kwanhun;Park, Min;Lee, Min Ho;Woo, Hyun Jun;Kim, Jong-Bae
    • Biomedical Science Letters
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    • v.22 no.3
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    • pp.83-97
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    • 2016
  • The measurement of viral load in HIV-1 infected patients is essential for the establishment of a therapeutic strategy. Several commercial assays have shown shortcomings in quantifying rare genotypes of HIV-1 such as minor groups of N and O. In this study, the HIV-1 RT-qPCR assay was developed. The primers and probe of HIV-1 were designed to target the pol gene and to increase the detection efficiency of various subtypes including group N and O. The HIV-1 quantitative RT-qPCR assay was assessed for its analytical performance and clinical evaluation. The LoD was determined to 33.9 IU/ml. The LoD of several subtypes including A, C, D, CRF_01AE, F, CRF_02AG, G and H, were determined to less than 40 IU/ml. The HIV-1 quantitative RT-qPCR assay was evaluated using the China National Reference Panel of HIV-1 RNA to determine the analytical performance. The results were all within the acceptable range. The clinical evaluation was performed at Hunan CDC in China. The clinical evaluation results were compared with those of the China domestic commercial kit. A significant correlation (fresh samples; $R^2=0.84$, P<0.001, frozen samples; $R^2=0.76$, P<0.001) between the two systems was observed for 64 fresh samples and 76 frozen samples with viral loads, and the Bland-Altman plot showed good agreement (98.4%, 96.1%, respectively). In conclusion, the HIV-1 quantitative RT-qPCR assay had comparable analytical performance with several commercial kits. The study provides basic data for the research of HIV-1 diagnosis and the development of P < HIV-1 molecular diagnostic assay.

Three Dimensional Correction Factors for the Added Mass Moment of Inertia of Ships in Torsional Vibration (선체(船體)비틂진동(振動)에 있어서의 부가관성(附加慣性)모우멘트 3차원수정계수(次元修正係數))

  • K.C.,Kim;H.S.,Lee
    • Bulletin of the Society of Naval Architects of Korea
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    • v.11 no.2
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    • pp.15-22
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    • 1974
  • As for the added mass moment of inertia of ships in torsional vibration, it seems that the works by T. Kumai[1,2] are the only systematic one available currently. The work[1] is for the calculation of the two dimensional correction factors with finitely-long elliptic cylinders as the mathematic model. In this work the authors recalculated the above factors, $J_{\tau}$, with the same mathematic model and the same problem formulation, and presented the numerical results in Fig. 1. The reason why the reinvestigation was done was that in Kumai's work he obtained the solutions of the Mathieu equations, which was derived from the problem formulation for the velocity potential, under the assumption that the dummy constant q involved in the equations was always far less than unity, whereas in fact it takes values within the region of $0<q{\leq}{\infty}$ in sequence. As a result the authors found two remarkable differences in general features of $J_{\tau}$(refer to Fg.3); one that the authors' numerical results are considerably higher than the results given in [2], and the other that for a given number of node those have properties of decreasing monotonically with increase of the beam-draft ratio while these rapidly decrease from a maximum value of near at B/T=2.00 with B/T becoming greater or less than ratio. It seems that the latter trend was resulted from the fact that the assumption of $q{\ll}1$ employed in [2] was more closely satisfied in the vicinity of B/T=2.00.

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Effect of Muscle Activation Change of Lower Limb According to Whole Body Vibration During Different Squat Exercises (다양한 스쿼트 자세 수행 시 전신진동자극이 하지 근 활성도에 미치는 영향)

  • Seo, S.B.;Kang, S.R.;Yu, C.H.;Min, J.Y.;Kwon, T.K.
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.8 no.1
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    • pp.33-40
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    • 2014
  • The objective of this study was to assess leg muscle activities during whole body vibration (WBV) training with various squat position exercises. Subjects performed four different squat exercises on a vibration platform (VM-10, Sonicworld Co.) Ten healthy women volunteers (age $21{\pm}1.3years$, height $160{\pm}2.1cm$, weight $52{\pm}4.6kg$) were selected. EMG signals four leg muscles were taken and analyzed. The exercises were performed both with 10 seconds WBV and without 10 seconds WBV. Muscle activities during WBV were compared with non-vibration stimulus. In the result, EMG signals caused by WBV were significantly higher (P<0.05) compared with non-vibration stimulus in all leg muscles and squat exercises. The increase in muscle activity caused by Whole body vibration was significantly higher (P<0.05) in LS and OS compared with HU&HS.

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Some biological notes on Eriophyes kuko KISHIDA (1) Its biology and life history (구기자 혹응애(Eriophyes kuko KISHIDA)에 관한 생태학적 지견 (1) 그의 생태 및 생활사)

  • Kim C. H.
    • Korean journal of applied entomology
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    • v.5_6
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    • pp.59-63
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    • 1968
  • This Paper deals With the biology and the life Cycle of Eriophyes kuko KISHIDA. 1. The host of Eriophyes kuko KISHIDA is Lycium chinense MILL (Boxthorn), Solanum nigrum LINNE(Morel) and Capacium annum LINNE(Red pepper) etc. 2. Eriophyes kuko KISHIDA is migrated and propagated by physical carriers. The direction of the wind has a great influence upon migration and dispersal. 3. The number of e99s deposited by a adult female is $28.5\pm0.449$ egg period is $7.0\pm0.447$ and larval period is $4.33\pm0.667$ days respectively. 4. The size of gall diameter on the leaf of Lycium Chinense MILL after boring in each date by Eriophyes kuke KISHIDA is as follows, 1st day after boring is $290.5\pm0.3415\mu$ End 25st day after boring is $3260.5\pm0.5157\mu$ in average. 5. Adult periods are from 25 to 30 days and the egg laying period is 6 days. 6. Eriophyes kuko KISHIDA has 6 to 7 generations in a year, and hibernate they over winter in the gall as an adult. The first adult appears in late May.

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A Study on the Classification of Nursing Diagnoses by Student Nurses (간호학생이 내린 간호진단 분석에 관한 연구)

  • Min, Soon
    • Journal of Korean Academy of Nursing
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    • v.25 no.3
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    • pp.457-471
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    • 1995
  • This research was done to promote improvement of practical application of nursing diagnoses and to improve the quality of nursing. The subjects of this research were 156 second year students of C junior nursing college who were giving adult patient care. The nursing diagnoses of 312 reports were analyzed using NANDA. In these case reports only nursing diagnoses were considered, of which there were a total of 982. In the data analysis the 9H of the nursing students' nursing diagnoses matched with 105 NANDA nursing diagnoses, Of these, the most frequent diagnoses were pain(165, 17.48%), anxiety(101, 10.70%), alteration in nutrition(83, 8.79%) , sleep disturbance (67, 7.10%), in activity intolerance (67, 7.10%), ineffective breathing pattern(51,5.40%). The etiology for the students' nursing diagnoses were compared with NANDA's nursing diagnoses by frequency. The most frequent etiology for the nursing diagnoses of pain was a biological etiology(50, 31%), for anxiety, situation crisis(58, 57.43%), for alteration in nutrition, indigesion(23, 27.71%), for sleep disturbance, external etiology(25, 37.32%), for activity intolerance, immobile position(22, 32.84%), for ineffective breathing pattern, pain(35, 68.63%), and for ,impaired physical mobility, pain(31, 65.96%). The most frequent etiology for constipation was inadquate digestion of water and cellulose (16, 34.78%), for fluid volume felicity, loss of body fluid (21, 52.50%), for impaired skin integrity, external etilogy(16, 43.24%), for impaired physical mobility, pain(22, 62.86%) , for knowledge deficits, cognition disturbance(9, 27.27%), for ineffective air way clearance, secretion obstruction(14, 48.27%) , for impaired gas exchange, loss of transport ability of blood oxygen(9, 37.50%) , and for powerlessness, therapy environment (5, 22.73%). The number of nursing diagnoses by pattern was exchange(16), moving(6), feeling(4), choosing(4), relating(3), communication(1), perceiving(1), knowing(1), valuing(1).

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Effects of an Integrated Self-Management Program on Self-Management, Glycemic Control, and Maternal Identity in Women with Gestational Diabetes Mellitus (통합 자가관리 프로그램이 임신성 당뇨병 임부의 자가관리, 혈당 및 모성 정체성에 미치는 효과)

  • Kim, HeeSook;Kim, Sue
    • Journal of Korean Academy of Nursing
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    • v.43 no.1
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    • pp.69-80
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    • 2013
  • Purpose: The purpose of the study was to investigate the effects of an integrated self-management program on self-management, glycemic control, and maternal identity in women with gestational diabetes mellitus (GDM). Methods: A non-equivalent control group non-synchronized quasi-experimental design was used. A total of 55 women with GDM were recruited from Cheil General Hospital, Seoul, Korea and were assigned to an experimental (n=28) or control group (n=27). The participants were 24-30 weeks pregnant women who had been diagnosed with GDM as of July 30, 2010. The program was conducted as a 1 hour small group meeting 3 out of 5 times and by telephone-counseling 2 out of 5 times. The integrated self-management program was verified by an expert panel. Results: Although there was no significant reduction in HbA1c (U= -1.17, p=.238), there were statistically significant increases in self-management (U= -3.80, p<.001) and maternal identity (U= -4.48, p<.001), and decreased 2-h postprandial glucose levels (U= -2.43, p<.015) in the experimental group compared to the control group. Conclusion: These findings suggest that an integrated self-management program for women with GDM improves self-management, maternal identity, and glycemic control. Further studies are needed to identify the effects of an integrated self-management program on pregnancy and neonatal outcomes.

Synthesis and Physical Properties of Decylbithiophene End-Capped Oligomers Based on Naphthalene, Anthracene and Benzo[1,2-b:4,5-b']dithiophene

  • Jang, Sang-Hun;Tai, Truong Ba;Kim, Min-Kyu;Han, Jeong-Woo;Kim, Yun-Hi;Shin, Sung-Chul;Yoon, Yong-Jin;Kwon, Soon-Ki;Lee, Sang-Gyeong
    • Bulletin of the Korean Chemical Society
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    • v.30 no.3
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    • pp.618-622
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    • 2009
  • The new candidates for OTFTs, which were composed of naphthalene, anthracene, benzo[1,2-b:4,5-b’]dithiophene and 2-decylbithiophene end-capper were synthesized under Suzuki coupling reaction conditions. All of the oligomers were characterized by FT-IR, mass analysis, UV-vis, PL spectrum, cyclic voltametry (CV), differential scanning calorimetry (DSC), thermal gravimetric analysis (TGA), $^1H-NMR\;and\;^{13}C-NMR$. Investigation of physical properties showed that all of the oligomers have higher oxidation potential and good thermal stability. Especially, DBT-DtB-DBT is soluble in common solvents and suitable for low cost processing technologies.

Nucleophilic Substitution Reactions of Phenyl Y-Substituted-Phenyl Carbonates with Butane-2,3-dione Monoximate and 4-Chlorophenoxide: Origin of the α-Effect

  • Kim, Min-Young;Min, Se-Won;Um, Ik-Hwan
    • Bulletin of the Korean Chemical Society
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    • v.34 no.1
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    • pp.49-53
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    • 2013
  • Second-order rate constants have been measured spectrophotometrically for the reactions of phenyl Y-substituted-phenyl carbonates 7a-g with butane-2,3-dione monoximate ($Ox^-$) in 80 mol % $H_2O$/20 mol % DMSO at $25.0{\pm}0.1^{\circ}C$. The ${\alpha}$-nucleophile $Ox^-$ is 53-95 times more reactive than the corresponding normal-nucleophile 4-$ClPhO^-$ toward 7a-g, indicating that the ${\alpha}$-effect is operative. The magnitude of the ${\alpha}$-effect (e.g., the $k_{Ox^-}/k_{4-ClPhO^-}$ ratio) is independent of the electronic nature of the substituent Y. The cause of the ${\alpha}$-effect for the reactions of 7a-g has been suggested to be ground-state (GS) effect rather than transition-state (TS) stabilization through a six-membered cyclic TS, in which $Ox^-$ behaves a general acid/base catalyst. This idea is further supported by the result that $OH^-$ exhibits negative deviation from the linear Br${\o}$nsted-type plot composed of a series of aryloxides, while $Ox^-$ deviates positively from the linearity. Differential solvation of the GS of $Ox^-$ and 4-$ClPhO^-$ has been suggested to be responsible for the ${\alpha}$-effect exerted by $Ox^-$.

Amperometric Glucose Biosensor Based on Sol-Gel-Derived Zirconia/Nafion Composite Film as Encapsulation Matrix

  • Kim, Hyun-Jung;Yoon, Sook-Hyun;Choi, Han-Nim;Lyu, Young-Ku;Lee, Won-Yong
    • Bulletin of the Korean Chemical Society
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    • v.27 no.1
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    • pp.65-70
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    • 2006
  • An amperometric glucose biosensor has been developed based on the use of the nanoporous composite film of sol-gel-derived zirconia and perfluorosulfonated ionomer, Nafion, for the encapsulation of glucose oxidase (GOx) on a platinized glassy carbon electrode. Zirconium isopropoxide (ZrOPr) was used as a sol-gel precursor for the preparation of zirconia/Nafion composite film and the performance of the resulting glucose biosensor was tuned by controlling the water content in the acid-catalyzed hydrolysis of sol-gel stock solution. The presence of Nafion polymer in the sol-gel-derived zirconia in the biosensor resulted in faster response time and higher sensitivity compared to those obtained at the pure zirconia- and pure Nafion-based biosensors. Because of the nanoporous nature of the composite film, the glucose biosensor based on the zirconia/Nafion composite film can reach 95% of steady-state current less than 5 s. In addition, the biosensor responds to glucose linearly in the range of 0.03-15.08 mM with a sensitivity of 3.40 $\mu$A/mM and the detection limit of 0.037 mM (S/N = 3). Moreover, the biosensor exhibited good sensor-to-sensor reproducibility (~5%) and long-term stability (90% of its original activity retained after 4 weeks) when stored in 50 mM phosphate buffer at pH 7 at 4 ${^{\circ}C}$.