• Title/Summary/Keyword: C1-C2 instability

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High Temperature Deformation Behavior of a NIMONIC 80A Ni-based Superalloy (Ni계 초내열합금 NIMONIC 80A의 고온변형거동)

  • Ha, M.C.;Hwang, S.W.;Kim, C.S.;Kim, C.Y.;Park, K.T.
    • Transactions of Materials Processing
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    • v.22 no.5
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    • pp.258-263
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    • 2013
  • The deformation behavior of NIMONIC 80A was studied in the high temperature range of $900{\sim}1200^{\circ}C$ and for strain rates varying between 0.02 and $20s^{-1}$ via the hot compression test. Processing maps for hot working were constructed on the basis of the power dissipation efficiency using a dynamic material model. The results showed that the strength during hot compression increased with increasing strain rate and decreasing temperature. At low strains, the processing map of NIMONIC 80A did not reveal any instability domain regardless of the strain rate and temperature. However, at high strains, the processing map exhibited an instability domain at a low strain rate of $0.2s^{-1}$ and within a temperature range of $900{\sim}960^{\circ}C$. In the instability domain, the deformed microstructure exhibited shear bands and carbide precipitation while, in the safe domain, full recrystallization occurred.

Targeting a Safe Entry Point for C2 Pedicle Screw Fixation in Patients with Atlantoaxial Instability

  • Chun, Hyoung-Joon;Bak, Koang-Hum
    • Journal of Korean Neurosurgical Society
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    • v.49 no.6
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    • pp.351-354
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    • 2011
  • Objective : This investigation was conducted to evaluate a new, safe entry point for the C2 pedicle screw, determined using the anatomical landmarks of the C2 lateral mass, the lamina, and the isthmus of the pars interarticularis. Methods : Fifteen patients underwent bilateral C1 lateral mass-C2 pedicle screw fixation, combined with posterior wiring. The C2 pedicle screw was inserted at the entry point determined using the following method : 4 mm lateral to and 4 mm inferior to the transitional point (from the superior end line of the lamina to the isthmus of the pars interarticularis). After a small hole was made with a high-speed drill, the taper was inserted with a 30 degree convergence in the cephalad direction. Other surgical procedures were performed according to Harm's description. Preoperatively, careful evaluation was performed with a cervical X-ray for C1-C2 alignment, magnetic resonance imaging for spinal cord and ligamentous structures, and a contrast-enhanced 3-dimensional computed tomogram (3-D CT) for bony anatomy and the course of the vertebral artery. A 3-D CT was checked postoperatively to evaluate screw placement Results : Bone fusion was achieved in all 15 patients (100%) without screw violation into the spinal canal, vertebral artery injury, or hardware failure. Occipital neuralgia developed in one patient, but this subsided after a C2 ganglion block. Conclusion : C2 transpedicular screw fixation can be easily and safely performed using the entry point of the present study. However, careful preoperative radiographic evaluation, regardless of methods, is mandatory.

The Complex Formation of Gallium Bromide with i-Propyl Bromide in Nitrobenzene (니트로벤젠용액내에서의 브롬화갈륨과 i-브롬화프로필과의 착물형성에 관한 연구)

  • Oh Cheun Kwun;Dong Sup Lee;Young Hoon Lee
    • Journal of the Korean Chemical Society
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    • v.29 no.1
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    • pp.9-14
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    • 1985
  • The solubilities of i-propyl bromide in nitrobenzene have been measured at 10$^{\circ}$, 19$^{\circ}$ and 25$^{\circ}C$ in the presence and absence of gallium bromide. In the presence of gallium bromide, 1 : 1 complex, i-C$_3$H$_7Br{\cdot}GaBr_3$ is formed in the solution. The instability constant K of the complex formation was evaluated from the following equilibrium equation: i-C$_3$H$_7Br{\cdot}GaBr_3$ ${\rightleftharpoons}$ i-C$_3$H$_7$Br + $\frac{1}{2}$$Ga_2Br_6$. The change of enthalpy, free energy and entropy for the dissociation of the complex were also calculated. From these result, it seems that the stabilities of the complex formation, gallium bromide with alkyl bromide, are directly related with those of the carbonium ions of alkyl bromide.

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Microsatellite Instability and p53, k-ras c-myc Oncoprotein Expression in Non-Small Cell Lung Carcinoma (비소세포 폐암에서의 Microsatellite Instability와 p53. K-ras, c-myc 암단백의 발현)

  • 나석주;곽문섭
    • Journal of Chest Surgery
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    • v.33 no.1
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    • pp.60-67
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    • 2000
  • Background: Microsatellites are short-tandem repeated uncleotide sequences present throughout the human genome. Alterations of microsatellites have been termed microsatellite instability(MI). It has been generally known that microsatellite instability detected in hereditary non-polyposis colorectal cancer (HNPCC) reflects genetic instability that is caused by impairments of DNA mismatch repair system regarding as a novel tumorigenic mechanism. A number of studies reported that MI occurred at varying frequencies in non-small cell lung carcinoma (NSCLC). However It has been unproven whether MI could be a useful market of genetic instability and have a clinical significance in NSCLC. Material and Method : We have examined whether MI can be observed in thirty NCSLC using polymerase chain reaction whether such alterations are associated with other molecular changes such as p53, K-ras and c-myc oncoproteins expression detected by immunohistochemical stain,. Result: MI(+) was observed in 16.6%(5/30) and MI(-) was 83.3% (25/30) Average age was 50$\pm$7.5 year-old in MI(+) group and 57$\pm$6.6 year-old in MI(-) group. Two year survival rate in MI(=) group (20% 1/5) was worse than MI(-) group (64% 16/25) with a statistic difference. (P=0.04) The positive rate of K-ras oncoprotein expression and simultaneous expression of 2 or 3 oncoproteins expression were higher in MI(+) group than MI(-) group with a statistic difference(P=0.05, P=0.01) Conclusion: From, these results the authors can conclude that MI is found in some NSCLC and it may be a novel tumorigenic mechanism in some NSCLC. We also conclude that MI could be used as another poor prognostic factor in NSCLS.

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Characterization of Hot Deformation Behavior of Ti-6Al-4V Alloy (Ti-6Al-4V 합금의 고온변형거동 규명)

  • 염종택;김두현;나영상;박노광
    • Transactions of Materials Processing
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    • v.10 no.4
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    • pp.347-354
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    • 2001
  • Compression tests were carried out to investigate the hot-deformation behavior of Ti-6Al-4V alloy in the temperature range of $915^{\circ}C$ to $1015^{\circ}C$ and the strain rate range of $10^{-3}s^{-i}$ to $10s^{-1}$. Under the given test conditions, the hot-deformation of Ti-6Al-4V alloy was mainly led by dynamic recovery rather than by dynamic recrystallization. The activation energy for the plastic deformation in $\alpha+\beta$ field was about 894 kJ/mol and $\beta$ field was 332kJ/mo1. Processing map for hot working are developed on the basis of the variations of efficiency of power dissipation($\eta$=2m/m+1) and flow instability criterion using the dynamic material model. The optimum process condition in the ($\alpha+\beta$) field was obtained at the temperature ranges of $930^{\circ}C$ to $955^{\circ}C$$^{\circ}C$ and a strain rate of $10^{-3}s{-1}$.

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Gravitational Instability of Rotating Isothermal Rings

  • Moon, Sanghyuk;Kim, Woong-Tae
    • The Bulletin of The Korean Astronomical Society
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    • v.41 no.2
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    • pp.61.2-61.2
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    • 2016
  • Nuclear rings at centers of barred galaxies exhibit strong star formation activities. They are thought to undergo gravitational instability when sufficiently massive. We approximate them as rigidly-rotating isothermal objects and investigate their gravitational instability. Using a self-consistent eld method, we first construct their equilibrium sequences specified by two parameters: ${\alpha}$ corresponding to the thermal energy relative to gravitational potential energy, and $R_B$ measuring the ellipticity or ring thickness. The density distributions in the meridional plane are steeper for smaller ${\alpha}$, and well approximated by those of infinite cylinders for slender rings. We also calculate the dispersion relations of nonaxisymmetric modes in rigidly-rotating slender rings with angular frequency ${\Omega}$ and central density ${\rho}_c$. Rings with smaller are found more unstable with a larger unstable range of the azimuthal mode number. The instability is completely suppressed by rotation when ${\Omega}$ exceeds the critical value. The critical angular frequency is found to be almost constant at $0.7(G{\rho}_c)^{1/2}$ for ${\alpha}$ > 0.01 and increases rapidly for smaller ${\alpha}$. We apply our results to a sample of observed star-forming rings and confirm that rings without a noticeable azimuthal age gradient of young star clusters are indeed gravitationally unstable.

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Cancellation of Phase Noise in 1.4 GHz RF Signal Transferred to a Remote Site through 13 km Fiber (13 km 광섬유를 통하여 원격지로 전송된 1.4 GHz RF 신호의 위상잡음 제거)

  • Lee, Won-Kyu;Park, Chang-Yong;Mun, Jong-Chul;Yu, Dai-Hyuk
    • Korean Journal of Optics and Photonics
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    • v.21 no.3
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    • pp.103-110
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    • 2010
  • A fiber-phase-noise compensating system was constructed for a 1.4 GHz reference frequency transferred through a 13-km-long fiber spool. The transfer instability was dependent on the temperature variation of the compensating system. With the room temperature variation stabilized within $0.3^{\circ}C$, the transfer instability was $4.6{\times}10^{-14}$ at 0.8 s of average time and $2.5{\times}10^{-16}$ at 1000 s of average time with the fiber phase noise compensated. However, with the room temperature changed by $3.5^{\circ}C$, the transfer instability was $6.8{\times}10^{-14}$ at 1.2 s of average time and $3.0{\times}10^{-15}$ at 1000 s of average time. From this result, the temperature stability condition for the experimental setup could be determined to obtain a transfer instability of $10^{-16}$ at 1000 s of average time.

Quantitative Difference in the Extinguishing Concentration of Inert Gases with Fire Suppression Criteria in a Cup Burner Test (컵버너시험에서 소화기준에 따른 불활성기체의 소화농도에 대한 정량적 차이)

  • Cho, Jae-Ho;Hwang, Cheol-Hong
    • Fire Science and Engineering
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    • v.28 no.3
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    • pp.34-42
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    • 2014
  • The concentrations of inert gases ($N_2$, Ar, $CO_2$ and He) required to induce the flame instabilities such as swing, rotation, lifted and blow-out were measured in a cup burner nonpremixed flames for $CH_4$ and $C_3H_8$ fuels. Quantitative differences in the extinguishing concentration with fire suppression criteria (i.e. blow-out or onset of flame instability) were also examined. It was found that the difference in extinguishing concentration was increased with the appearance of lifted flame and the low extinguishing performance of inert gaseous. The maximum difference in extinguishing concentration with the suppression criteria was approximately 35% at the highest fuel velocity condition (1.3 cm/s) for the $C_3H_8$-air nonpremixed flame. It can be also expected that the extinguishing concentration by the criteria based on the onset of flame instability will provide the useful information from the viewpoint of the accurate and economical design concentration.

Comparison of Outcomes after Atlantoaxial Fusion with Transarticular Screws and Screw-Rod Constructs

  • Kim, Ji Yong;Oh, Chang Hyun;Yoon, Seung Hwan;Park, Hyeong-Chun;Seo, Hyun Sung
    • Journal of Korean Neurosurgical Society
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    • v.55 no.5
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    • pp.255-260
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    • 2014
  • Objective : The purpose of this study was to compare the radiological and neurological outcomes between two atlantoaxial fusion method for atlantoaxial stabilization; C1 lateral mass-C2 pedicle screws (screw-rod constructs, SRC) versus C1-2 transarticular screws (TAS). Methods : Forty-one patients in whom atlantoaxial instability was treated with atlantoaxial fixation by SRC group (27 patients, from March 2005 to May 2011) or TAS group (14 patients, from May 2000 to December 2005) were retrospectively reviewed. Numeric rating scale (NRS) for pain assessment, Oswestry disability index (ODI), and Frankel grade were also checked for neurological outcome. In radiologic outcome assessment, proper screw position and fusion rate were checked. Perioperative parameters such as blood loss during operation, operation time, and radiation exposure time were also reviewed. Results : The improvement of NRS and ODI were not different between both groups significantly. Good to excellent response in Frankel grade is shown similarly in both groups. Proper screw position and fusion rate were also observed similarly between two groups. Total bleeding amount during operation is lesser in SRC group than TAS group, but not significantly (p=0.06). Operation time and X-ray exposure time were shorter in SRC group than in TAS group (all p<0.001). Conclusion : Both TAS and SRC could be selected as safe and effective treatment options for C1-2 instability. But the perioperative result, which is technical demanding and X-ray exposure might be expected better in SRC group compared to TAS group.