• Proceedings of the Korea Institute of Convergence Signal Processing
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• 2001.06a
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• pp.109-112
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• 2001

기존의 K-means 알고리즘은 학습벡터가 단일군집에 할당되는 방법이 crisp 이므로 다른 군집에 할당될 확률을 무시하게 된다. 따라서 군집화 작업과 관련하여 반복적인 코드북 설계 과정에서 각 학습벡터를 다중 군집으로 할당하는 Fuzzy c-means를 사용한다. 또한 Fuzzy c-means 알고리즘의 학습과정에서 구해지는 각 클래스 의 프로토타입에 가중치를 곱하여 다음 학습의 프로토타입으로 사용함으로써 Fuzzy c-means 알고리즘 적용 결과 얻어지는 코트북의 성능을 기존 알고리즘과 비교하여 개선된 Fuzzy c-means 알고리즘을 찾기 위한 근거를 마련한다.

• Tuberculosis and Respiratory Diseases
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• v.43 no.2
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• pp.123-127
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• 1996

Secretion of surfactant phospholipid can be stimulated by a variety of agonists acting via at least three different signal transduction mechanisms. These include the adenylate cyclase system with activation of cAMP-dependent protein kinase; activation of protein kinase C either directly or subsequent to activation of phosphoinositide-specific phospholipase C and generation of diacylglycerols and inositol trisphosphate; and a third mechanism that involves incresed $Ca^{2+}$ levels and a calmodulin-dependent step. ATP stimulates secretion via all three mechanisms. The protein kinase C pathway is also coupled to phopholipase D which, acting on relatively abundant cellular phospholipids, generates diacylglycerols that further activate protein kinase C. Sustained protein kinase C activation can maintain phosphatidylcholine secretion for a prolonged period of time. It is likely that interactions between the different signaling pathways have an important role in the overall physiological regulation of surfactant secretion.

• Journal of Life Science
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• v.8 no.1
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• pp.102-108
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• 1998

The nascent from of glycosylphosphatidylinositol (GPI)-anchored proteins possesses both amino and carboxy terminal hydrophobic signal sequences to direct processing in the endoplasmic reticulum (ER). Following cleavage of the amino-terminal signal peptide, the carboxy-terminal peptide is processed. Previously, mouse lymphocyte NDA: agrinine ADP-ribosyltransferase (Yac-1) was cloned and the deduced amino acid sequence of the Yac-1 transferase contained hydrophobic amino and carboxy termini, consistent with known signal sequences of GPI-anchored proteins. This tranferase was present on the surface of NMU (rat mammary adenocarcinoma) cells transfected with the wildtype cDNA and was released with phosphatidylinositol-specific phosphilpase C. Expression of the mutant protein, lacking the carboxy terminal hydrophobic sequence, resulted in the peoduction of soluble, secreted from of the transferase. This result shows that carboxy terminal sequence is important for GPI-attachment.

• Journal of Advanced Navigation Technology
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• v.26 no.2
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• pp.78-84
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• 2022

In this paper, we propose a closed-form based 3D localization method in the presence of multiple signal sources. General localization methods such as TDOA, AOA, and FDOA can estimate a location when a single signal source exists. When there are multiple unknown signal sources, there is a limit in estimating the location. The proposed method calculates a cross-correlation vector of signals received by sensors having an array antenna, and estimates TDOA and AOA values from the cross-correlation values. Then, the coordinate transformation is performed using the position of the reference sensor. Then, the coordinate rotation is performed using the estimated AOA value for the transformed coordinates, and then the three-dimensional position of each emitter is estimated. The proposed method verifies its performance through computer simulation.

• Investigative Magnetic Resonance Imaging
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• v.26 no.2
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• pp.125-134
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• 2022

Purpose: The aim of this study was to investigate the change in signal sensitivity over different acquisition start times and optimize the scanning window to provide the maximal signal sensitivity of [1-¹³C]pyruvate and its metabolic products, lactate and alanine, using spatially localized hyperpolarized 3D ¹³C magnetic resonance spectroscopic imaging (MRSI). Materials and Methods: We acquired 3D ¹³C MRSI data from the brain (n = 3), kidney (n = 3), and liver (n = 3) of rats using a 3T clinical scanner and a custom RF coil after the injection of hyperpolarized [1-¹³C]pyruvate. For each organ, we obtained three consecutive 3D ¹³C MRSI datasets with different acquisition start times per animal from a total of three animals. The mean signal-to-noise ratios (SNRs) of pyruvate, lactate, and alanine were calculated and compared between different acquisition start times. Based on the SNRs of lactate and alanine, we identified the optimal acquisition start timing for each organ. Results: For the brain, the acquisition start time of 18 s provided the highest mean SNR of lactate. At 18 s, however, the lactate signal predominantly originated from not the brain, but the blood vessels; therefore, the acquisition start time of 22 s was recommended for 3D ¹³C MRSI of the rat brain. For the kidney, all three metabolites demonstrated the highest mean SNR at the acquisition start time of 32 s. Similarly, the acquisition start time of 22 s provided the highest SNRs for all three metabolites in the liver. Conclusion: In this study, the acquisition start timing was optimized in an attempt to maximize metabolic signals in hyperpolarized 3D ¹³C MRSI examination with [1-¹³C] pyruvate as a substrate. We investigated the changes in metabolic signal sensitivity in the brain, kidney, and liver of rats to establish the optimal acquisition start time for each organ. We expect the results from this study to be of help in future studies.

• 한국초전도학회:학술대회논문집
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• v.16
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• pp.45-45
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• 2006

• The Transactions of the Korean Institute of Electrical Engineers C
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• v.55 no.4
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• pp.166-171
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• 2006

In this paper, we have studied for analysis of the partial discharge(PD) signal in underground transmission line. The PD signal has estimated as detected signal accumulation of a PRPDA method by using Labview, and analyzed with fuzzy algorithm. In our algorithm, we developed system configuration that detected accumulating PD signal using by Labview and programmed fuzzy algorithm can be analyzed the PD signal using with Matlab. With practical PD logic implementation of theoretical detected system and hardware implementation, the device for Hipotronics Company's 50kV setup has generated and then has applied with $15k{\sim}17kV$ with 1:1 time probe. It's also used the LDPE 0.27mmt (scratch error 0.05mmt) to sample for making PD. In conclusion, Our new class of PD detected algorithm has also compared with previous PRPDA or Fuzzy algorithm. which has diagnose more conveniently by adding numerical values.

• Journal of Power System Engineering
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• v.14 no.6
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• pp.41-46
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• 2010

Acoustic emission (AE) technique is a well-known non-destructive test technique. Fatigue crack growth test was performed using SM53C to check up the AE signal occurred by crack growth, so AE system was used to detect the crack signal. Features calculated by the AE signals were analyzed to evaluate the steps divided the crack growth into three. The steps, initiation, growth and breaking, were separated by velocity of the crack growth. Time waveform and power spectrum were created by the AE signal of each one of the steps and compared. In the feature domains, it was found that AE values changed rapidly as the velocity of the crack increasing.

• Journal of the Institute of Convergence Signal Processing
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• v.8 no.4
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• pp.285-292
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• 2007

SoC which deploys software modules as well as hardware IPs on a single chip is a major revolution taking place in the implementation of a system design, and high-level synthesis is an important process of SoC design methodology. Recently, SPARK parallelizing high-level synthesis software tool has been developed. It takes a behavioral ANSI-C code as an input, schedules it using code motion and various code transformations, and then finally generates synthesizable RTL VHDL code. Although SPARK employs various loop transformation algorithms, the synthesis results generated by SPARK are not acceptable for basic signal and image processing algorithms with nested loop. In this paper we propose a SoC platform with an application-specific PLD targeting local operations which are feature of many loop algorithms used in signal and image processing, and demonstrate design process which maps behavioral specification with nested loops written in a high-level language (ANSI-C) onto 2D systolic array. Finally the derived systolic array is implemented on the proposed application-specific PLD of SoC platform.

• BMB Reports
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• v.32 no.3
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• pp.215-225
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• 1999

Phytochromes (with gene family members phyA, B, C, D, and E) are a wavelength-dependent light sensor or switch for gene regulation that underscore a number of photo responsive developmental and morphogenic processes in plants. Recently, phytochrome-like pigment proteins have also been discovered in prokaryotes, possibly functioning as an auto-phosphorylating/phosphate-relaying two-component signaling system (Yeh et al., 1997). Phytochromes are photochromically convertible between the light sensing Pr and regulatory active Pfr forms. Red light converts Pr to Pfr, the latter having a "switch-on" conformation. The Pfr form triggers signal transduction pathways to the downstream responses including the expression of photosynthetic and other growth-regulating genes. The components involved in and the molecular mechanisms of the light signal transduction pathways are largely unknown, although G-proteins, protein kinases, and secondary messengers such as $Ca^{2+}$ ions and cGMP are implicated. The 124-127 kDa phytochromes form homodimeric structures. The N-terminal half contains the tetrapyrrolic phytochromobilin for red/far-red light absorption. The C-terminal half includes both a dimerization motif and regulatory box where the red light signal perceived by the chromophore-domain is recognized and transduced to initiate the signal transduction cascade. A working model for the inter-domain signal communication within the phytochrome molecule is proposed in this Review.