• Title/Summary/Keyword: C-factor

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Pervaporation Separation Characteristics for Water-Ethanol Mixtures Using Porous Hollow Fiber PVA Composite Membranes (미세 다공성 중공사 PVA복합막을 이용한 에탄올 수용액의 투과증발분리 특성)

  • Kim, Ji Seon;Park, Hun Whee;Seo, Chang Hee;Rhim, Ji Won
    • Membrane Journal
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    • v.23 no.5
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    • pp.360-366
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    • 2013
  • The Poly (vinylidene fluoride) and poly (acrylonitrile) (PAN) hollow fiber composite membranes coated with poly (vinyl alcohol) (PVA) and poly (acrylic acid) (PAA) as the crosslinkig agent are prepared. The resulting membranes were characterized for aqueous 90 wt% ethanol solution by pervaporation techniques in terms of the permeability and separation factor. In general, as both the crsslinking reaction temperature and the crosslinking agent concentration increase, the permeability decrease while the separation factor tends to increase. And also the permeability increased and the separation factor decreased as the feed temperature increased. Typically, the permeability $502g/m^2hr$ at the feed temperature $70^{\circ}C$ was obtained for PVDF hollow fiber membrane prepared with the crosslinking agent PAA 3 wt% at the reaction temperature $60^{\circ}C$ whereas the separation factor 218 was shown for the membrane reacted with PAA 11 wt% and at $100^{\circ}C$ for the feed temperature $50^{\circ}C$.

Methanol extract of Myelophycus caespitosus ameliorates oxidative stress-induced cytotoxicity in C2C12 murine myoblasts via activation of heme oxygenase-1

  • Cheol Park;Hyun Hwangbo;Min Ho Han;Jin-Woo Jeong;Suengmok Cho;Gi-Young Kim;Hye-Jin Hwang;Yung Hyun Choi
    • Fisheries and Aquatic Sciences
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    • v.26 no.1
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    • pp.35-47
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    • 2023
  • Myelophycus caespitosus, a brown alga belonging to genus Myelophycus, has been traditionally used as a food and medicinal resource in Northeastern Asia. However, few studies have been conducted on its pharmacological activity. In this study, we evaluated whether methanol extract of M. caespitosus (MEMC) could protect against oxidative damage caused by hydrogen peroxide (H2O2) in C2C12 murine myoblasts. Our results revealed that MEMC could suppress H2O2-induced growth inhibition and DNA damage while blocking the production of reactive oxygen species. In H2O2-treated cells, cell cycle progression was halted at the G2/M phase, accompanied by changes in expression of key cell cycle regulators. However, these effects were attenuated by MEMC. In addition, we found that MEMC protected cells from induction of apoptosis associated with mitochondrial impairment caused by H2O2 treatment. Furthermore, MEMC enhanced the phosphorylation of nuclear factor-erythroid-2 related factor 2 (Nrf2) and expression and activity of heme oxygenase-1 (HO-1) in H2O2-treaetd C2C12 myoblasts. However, such anti-apoptotic and cytoprotective effects of MEMC were greatly abolished by HO-1 inhibitor, suggesting that MEMC could increase Nrf2-mediated activity of HO-1 to protect C2C12 myoblasts from oxidative stress.

Quality Verification for Respiratory Gated Proton Therapy (호흡동조 양성자치료의 Quality Verification)

  • Kim, Eun Sook;Jang, Yo Jong;Park, Ji Yeon;Kang, Dong Yun;Yeom, Doo Seok
    • The Journal of Korean Society for Radiation Therapy
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    • v.25 no.2
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    • pp.107-113
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    • 2013
  • Purpose: To verify accuracy of respiratory gated proton therapy by measuring and analyzing proton beam delivered when respiratory gated proton therapy is being performed in our institute. Materials and Methods: The plan data of 3 patients who took respiratory gated proton therapy were used to deliver proton beam from proton therapy system. The manufactured moving phantom was used to apply respiratory gating system to reproduce proton beam which was partially irradiated. The key characteristics of proton beam, range, spreat-out Bragg peak (SOBP) and output factor were measured 5 times and the same categories were measured in the continuous proton beam which was not performed with respiratory gating system. Multi-layer ionization chamber was used to measure range and SOBP, and Scanditronix Wellhofer and farmer chamber was used to measure output factor. Results: The average ranges of 3 patients (A, B, C), who had taken respiratory gated proton therapy or not, were (A) 7.226, 7.230, (B) 12.216, 12.220 and (C) 19.918, 19.920 $g/cm^2$ and average SOBP were (A) 4.950, 4.940, (B) 6.496, 6.512 and (C) 8.486, 8.490 $g/cm^2$. And average output factor were (A) 0.985, 0.984 (B) 1.026, 1.027 and (C) 1.138, 1.136 cGy/MU. The differences of average range were -0.004, -0.004, -0.002 $g/cm^2$, that of SOBP were 0.010, -0.016, -0.004 $g/cm^2$ and that of output factor were 0.001, -0.001, 0.002 cGy/MU. Conclusion: It is observed that the range, SOBP and output factor of proton beam delivered when respiratory gated proton therapy is being performed have the same beam quality with no significant difference compared to the proton beam which was continuously irradiated. Therefore, this study verified the quality of proton beam delivered when respiratory gated proton therapy and confirmed the accuracy of proton therapy using this.

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Numerical Studies on Bearing Capacity Factor Nγ and Shape Factor of Strip and Circular Footings on Sand According to Dilatancy Angle (모래지반에서 팽창각에 따른 연속기초와 원형기초의 지지력계수 Nγ와 형상계수에 대한 수치해석 연구)

  • Kim, Dong-Joon;Youn, Jun-Ung;Jee, Sung-Hyun;Choi, Jaehyung;Lee, Jin-Sun;Kim, Dong-Soo
    • Journal of the Korean Geotechnical Society
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    • v.30 no.1
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    • pp.49-63
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    • 2014
  • Bearing capacity factor $N_{\gamma}$ and shape factor were studied for rigid strip and circular footings with a rough base on sand by numerical modelling considering the effect of dilation angle. The numerical model was developed with an explicit finite difference code. Loading procedures and interpretation methods were devised in order to shorten the running time while eliminating the exaggeration of the reaction caused by the explicit scheme. Using the Mohr-Coulomb plasticity model with associated (${\psi}={\phi}$) and nonassociated (${\psi}$ < ${\phi}$) flow-rules, the bearing capacity factor $N_{\gamma}$ was evaluated for various combinations of internal friction angles and dilation angles. Bearing capacity factor decreased as the dilation angle was reduced from the associated condition. An equation applicable to typical sands was proposed to evaluate the relative bearing capacity for the nonassociated condition compared to the associated condition on which most bearing capacity factor equations are based. The shape factor for the circular footing varied substantially when the plane-strain effect was taken into account for the strip footing. The numerical results of this study showed closer trends with the previous experimental results when the internal friction angle was increased for the strip footing. Discussions are made on the reason that previous equations for the shape factor give different results and recommendations are made for the appropriate design shape factor.

Electric Degradation of Failure Mode of Solar Cell by Thermal Shock Test (열충격 시험 후 태양전지 파괴 모드에 따른 전기적 특성변화)

  • Kang, Min-Soo;Jeon, Yu-Jae;Shin, Young-Eui
    • Journal of Energy Engineering
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    • v.22 no.4
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    • pp.327-332
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    • 2013
  • 일본 연구에서는 열충격 시험을 통한 태양전지의 파괴모드에 따른 전기적 특성을 분석하였다. 시편은 Photovoltaic Module을 만들기 전 3 line Ribbon을 Tabbing한 단결정 Solar Cell을 제작하였다. 열충격 시험 Test 1의 온도조건은 저온 $-40^{\circ}C$, 고온 $85^{\circ}C$, Test 2는 저온 $-40^{\circ}C$, 고온 $120^{\circ}C$에서 Ramping Time을 포함하여 각각 15분씩, 총 30분을 1사이클로 500사이클을 각각의 조건으로 수행하였다. 열충격 시험 후 Test 1에서는 4.0%의 효율 감소율과 1.5%의 Fill Factor 감소율을 확인하였으며, Test 2에서는 24.5%의 효율 감소율과 11.8%의 Fill Factor 감소율을 확인하였다. EL(Electroluminescence)촬영 및 단면을 분석한 결과, Test 1과 Test 2 시편 모두 Cell 표면 및 내부에서의 Crack이 발견되었다. 하지만, Test 2의 시험이 Test 1보다 가혹한 온도조건의 시험으로 인해 Test 1에서 나타나지 않았던, Cell 파괴를 Test 2에서 확인하였다. 결국, Test 1에서 효율의 직접적인 감소 원인은 Cell 내부에서의 Crack이며, Test 2에서는 Cell 내부에서의 Crack 및 Cell 파괴로 인한 Cell 자체의 성능저하로 효율이 크게 감소한다는 것을 본 실험을 통하여 규명하였다.

Power Factor Correction of Switched Reluctance Motor Drive System using Boost Converter (승압형 컨버터를 이용한 SRM의 구동시스템 역률개선)

  • Yoon Yong-Ho;Kim Jae-Moon;Lee Tae-Won;Kim Hack-Seong;Won Chung-Yuen
    • The Transactions of the Korean Institute of Power Electronics
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    • v.10 no.3
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    • pp.211-218
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    • 2005
  • Switched Reluctance Motor(SRM) offers the advantages of simple and robust motor construction, high speed and high efficiency over a wide operating range of torque and speed, excellent controllability. However SRM has the disadvantages of high current harmonics, and low power factor because the required output of speed and torque is produced by the discontinuous and loss of power system, and brings about the incorrect operation of electronic system. This paper deals with an energy efficient converter fed SRM system with the reduced harmonics and improved power factor. The validity of the proposed scheme is verified via experiments. We are implemented the proposed control system using 80C196KC micro-controller.

Microwave Dielectric Properties of (1-x)ZnWO4-xTiO2 Ceramics ((1-x)ZnWO4-xTiO2 세라믹스의 마이크로파 유전특성)

  • 윤상옥;김대민;심상흥;강기성
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.16 no.5
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    • pp.397-403
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    • 2003
  • Microwave dielectric properties of (1-x)ZnW $O_4$-xTi $O_2$ ceramic systems were investigated with calcination temperatures and Ti $O_2$ contents. The ZnW $O_4$ ceramic could be suitably sintered at 1075$^{\circ}C$ and showed the dielectric constant of 13.6, quality factor(Q$\times$ $f_{O}$value) of 22,000 and temperature coefficient of resonant frequency($\tau$$_{f}$) of -65$\pm$2ppm/$^{\circ}C$. Increasing the amount of Ti $O_2$ in the range of 0.25 to 0.45 mol, the dielectric constant and $\tau$$_{f}$ increased due to the role of Ti $O_2$ but the quality factor decreased due to the increase of phase boundaries. The 0.7ZnW $O_4$-0.3Ti $O_2$ ceramic showed the dielectric constant of 19.8, qualify factor(Q$\times$ $f_{0}$) of 20,000 and $\tau$$_{f}$ of -3$\pm$1ppm/$^{\circ}C$.>.EX>.>.>.

A study on the electrical characteristic of PZT ceramics with additive. (첨가제에 의한 PZT세라믹의 전기적 특성에 관한 연구)

  • 김현철;김진섭;김혁동;배선기
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1999.11a
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    • pp.236-239
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    • 1999
  • This paper is the study for electrical characteristic of PZT ceramics with Sb$_2$O$_3$, CoO additive. Effect of Sb$_2$O$_3$, CoO additive ranged from 0.0 wt% to 1.2wt% on the electrical characteristic of the PZT ceramics have been investigated. In the case of Sb$_2$O$_3$ 0.6wt%, the maximum vague of mechanical quality factor(Qm) was obtained 124.11 at l15$0^{\circ}C$. And, additive CoO 1.2wt% was obtained 184.12 at l15$0^{\circ}C$. The electromechanical coupling factor(kp) was increased by increasing the amount of Sb$_2$O$_3$, CoO additive. The maximum value of electromechanical coupling factor(kp) was obtained 58.35 with Sb$_2$O$_3$1.2wt% additive at l15$0^{\circ}C$. Dopped with additive CoO 0.9wt%, electromechanical coupling factor(kp) was obtained 47.84 at 115$0^{\circ}C$.

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Induction of Maturation Promoting Factor in Runo Oocvtes by Protein Kinase C Activation in uitro. (개구리 난자에서 Protein Kinase C의 활성화에 의한 Maturation Promoting Factor의 생성유도)

  • 유영란;임욱빈
    • The Korean Journal of Zoology
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    • v.35 no.3
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    • pp.277-286
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    • 1992
  • 개구리의 난자로 부터 maturation promoting factor(MPF)를 추출, 부분 분리하여 이들의 활성을 조사하고 이 물질의 생성과 protein kinase C(반KC)와의 관계를 조사하SB다. 성숙된 난자를 분쇄한 후 초원심분리과정을 거쳐 MPF의 crude extract(CE)를 얻은 다음 ultrafiltration (UF)과 고속액체크로마토그라피를 거쳐서 3종류의 분획 (peak 1, 11, and 111)을 얻었다. 이들 분획을 in nitro assay와 autoradiDgraphy를 사용하여 확인한 결과 분획 11에서 MPF 활성이 있는 것을 알았다. 분리 단계에 따라 MPF의 정제도를 Hl histone kinase assay로 조사한 결깍 UF를 거친 것은 CE보다 약 3배로, 분획 11에서는 약 117배로 증가한 것을 확인하였다. 또한 MPF분획의 인산화를 autoradiography로 조사한 결과 45 KD 단백질을 포함한 수종의 난자 단백질이 강하게 인산화되었음을 알 수 있었다. PKC의 활성화가 난자내 MPF의 생성을 유도하는가를 보기 위하여 PKC의 활성제인 12-0-tetradecanoyl phorbol 13 acetate(TPA)를 처리한 난자의 세포질 추출물을 미세주입 법으로 조사한 결과 TPA 처리 후 6시간부터 난자내 MPF의 활성이 나타나는 것을 알 수 있었다. 이러한 결과들은 PKC의 활성화가 MPF의 생성을 유도하고, MPF의 활성화와 함께 일부 단백질들의 인산화를 통하여 궁극적으로 난자 성숙을 촉진했음을 시사한다.

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