• 제목/요약/키워드: C&SD

검색결과 941건 처리시간 0.025초

Serum Amyloid A as an Independent Prognostic Factor for Renal Cell Carcinoma - A Hospital Based Study from the Western Region of Nepal

  • Mittal, Ankush;Poudel, Bibek;Pandeya, Dipendra Raj;Gupta, Satrudhan Pd;Sathian, Brijesh;Yadav, Shambhu Kumar
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권5호
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    • pp.2253-2255
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    • 2012
  • Objective: The objective of our present study was to assess the role of serum amyloid A (SAA) in stages and prognosis of renal cell carcinoma. Material and Methods: It was a hospital based retrospective study carried out in the Department of Medicine and Biochemistry of Manipal Teaching Hospital, Pokhara, Nepal between $1^{st}$ January 2008 and $31^{st}$ December 2011. The variables collected were SAA, CRP. Approval for the study was obtained from the institutional research ethical committee. Quantitative analysis of human SAA and C-reactive protein (CRP) was performed by radial immune diffusion (RID) assay for all cases. Results: Of the 422 total cases of renal cell carcinoma, 218 patients had normal and 204 abnormal SAA. SAA levels were grossly elevated in T3 stage ($122.3{\pm}SD35.7$) when compared to the mean for the T2 stage ($84.2{\pm}SD24.4$) (p value: 0.0001). Similarly, SAA levels were grossly elevated in M1 stage ($190.0{\pm}SD12.7$) when compared to the M0 stage ($160.9{\pm}SD24.8$) (p: 0.0001). There was no significant association with elevated CRP levels ($209.1{\pm}SD22.7$, normal $199.0{\pm}SD19.5$). Conclusion: The validity of SAA in serum as being of independent prognostic significance in RCC was demonstrated with higher levels in advanced stage disease.

Component Characteristics of Xanthoceras sorbifolium Seeds for Bioenergy Plant Utilization

  • Lee, Hyunseok;Yi, Jaeseon;An, Chanhoon;Kim, Minsu;Lee, Jeonghoon
    • Journal of Forest and Environmental Science
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    • 제31권4호
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    • pp.272-279
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    • 2015
  • Xanthoceras sorbifolium is considered as bio-energy crops owing to the high oil content from kernel. This study was performed to analyze calorific value, crude ash content, ultimate ratio, crude lipid and fatty acid composition among seed sources. Calorific values ranged from $4,526.0\;cal\;g^{-1}$ to $7,377.2\;cal\;g^{-1}$ in seeds and kernels showed the highest value. Calorific values and crude ash contents were observed as significant difference among plantations and/or individuals (p>0.05). Kernel from SD-F plantation showed the highest calorific value and lower crude ash content. C content comprised 63.4%, the highest levels was detected from SD-F (64.8%). Crude lipid content in kernel observed as 54.5 g $100\;g^{-1}$ from SD-F. In contrast it was determined the lowest value from LN-JARS as 46.5 g $100\;g^{-1}$. The fatty acid composition of kernel was determined to those of oleic acid (31.3%) and linoleic acid (38.1%) from SD-F and LN-JARS. These results will be offered to useful information for breeding materials selection.

High Speed SD-OCT System Using GPU Accelerated Mode for in vivo Human Eye Imaging

  • Cho, Nam Hyun;Jung, Unsang;Kim, Suhwan;Jung, Woonggyu;Oh, Junghwan;Kang, Hyun Wook;Kim, Jeehyun
    • Journal of the Optical Society of Korea
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    • 제17권1호
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    • pp.68-72
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    • 2013
  • We developed an SD-OCT (Spectral Domain-Optical Coherence Tomography) system which uses a GPU (Graphics Processing Unit) for processing. The image size from the SD-OCT system is $1024{\times}512$ and the speed is 110 frame/sec in real-time. K-domain linearization, FFT (Fast Fourier Transform), and log scaling were included in the GPU processing. The signal processing speed was about 62 ms using a CPU (Central Processing Unit) and 1.6 ms using a GPU, which is 39 times faster. We performed an in-vivo retinal scan, and reconstructed a 3D visualization based on C-scan images. As a result, there were minimal motion artifacts and we confirmed that tomograms of blood vessels, the optic nerve, and the optic disk are clearly identified. According to the results of this study, this SD-OCT can be applied to real-time 3D display technology, particularly auxiliary instruments for eye operations in ophthalmology.

노후 학교건물의 유지관리비용 정책 평가를 위한 시스템 다이내믹스 모델 (A System Dynamics Model for Evaluation of Maintenance Cost Policy in Deteriorated School Building)

  • 강수현;김상용
    • 대한건축학회논문집:구조계
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    • 제35권12호
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    • pp.181-188
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    • 2019
  • The maintenance of school building is pivotal issue. However, it is difficult to obtain basic analysis data for LCC(Lifecycle Cost) analysis and maintenance planning of school building. Therefore, this study proposed System Dynamics(SD) techniques to make maintenance decisions for school building. The interaction between the major parameters related to the aging of a building, maintenance activities, and cost were expressed in Causal Loop Diagram. Based on this, the formula for the relationship between causal maps was defined and converted to Stock and Flow Diagram. Through the completed SD model the 50-year plan of 214 educational building were tested by considered in account budget, maintainability, and budget allocation opinions. As a result, the integrated SD model demonstrated that it can support strategic decision making by identifying the status class and LCC behavior of school buildings by scenario. According to the scenario analysis, the rehabilitation action of preventive maintenance that primarily repairs the buildings in condition grade C showed the best performance improvement effect relative to the cost. Therefore, if the proposed SD model is expanded to consider the effects of other educational policies, the crucial performance improvement budget can be estimated in the long-term perspective.

포도 품종을 달리한 한국산 포도주의 제조 및 기호도 분석 (Development of Korean Red Wines Using Various Grape Varieties and Preference Measurement)

  • 이승주;이장은;김성수
    • 한국식품과학회지
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    • 제36권6호
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    • pp.911-918
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    • 2004
  • 국내산 거봉, 캠벨, 머스켓 베일리 A, 쉐레단 품종을 이용하여 일반 적포도주와 스위트 와인을 제조하였으며, 사이벨 품종을 이용하여 백포도주, 네오머스켓 품종의 화이트 스위트 와인을 제조하였다. 본 실험의 결과 적포도주 제조에는 캠벨과 머스켓 베일리 A 품종이 타 품종과 비교해 적합한 산도 및 색도를 보였으나, 캠벨의 경우 당 함량이 다소 낮고 신 맛이 강한 결함이 있어 이를 위한 향후 가당 방법 및 포도재배 연구가 필요할 것으로 보인다. 백포도주 제조용 품종인 사이벨의 경우 산도가 매우 높아 발효에 적합하지 않았으며, 신맛의 증가로 인해 기호도가 떨어져 이를 보완할 수 있는 감산 연구가 요구된다. 기호도 조사 결과 품종 별로는 캠벨, 머스켓 베일리 A로 제조된 포도주의 기호도가 높게 나타났다. 향후 선별된 품종을 이용한 포도주의 고품질화 연구가 수행될 예정이며 축척된 제조 기술로 현지의 기술 지도를 통하여 제품의 산업화 및 상품화에 기여하고자 한다.

SALS를 이용한 고분자용액의 상전환 기구에 관한 연구 : C1-C4 알콜의 첨가에 따른 상분리 거동에 미치는 효과와 투과 특성 (The study of phase inversion of polymer solutions using small angle light scattering (SALS): The effect of addition of alcohol (C1-C4) on phase separation behavior and hydraulic permeation)

  • Kang, Jong-Seok;Lee, Young-Moo
    • 한국막학회:학술대회논문집
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    • 한국막학회 2002년도 춘계 총회 및 학술발표회
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    • pp.81-85
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    • 2002
  • Small angle light scattering and field emission scanning electron microscope have been used to quantify the kinetics of liquid-liquid separation behavior during water vapor(RH52%[$\pm$3%] at 27$^{\circ}C$) quenching (non-solvent induced phase separation, NIPS) of polysulfone/NMP/Alcohol and CPVC/THF/Alcohol, respectively. Time dependence of the position of the light scattering maximum was observed at polysufone dope solutions, confirming spinodal secomposition (SD). while CPVC dope solutions showed a decreased scattered light intensity with a increased q-valuel, indicating nucleation & growth (NG). For the each system, domain growth rate in the intermediate and late stage of phase separation decreased with increasing the number of carbon of alcohol used as additive (non-solvent). Also, in the early stage for SD, the scattering intensity with time was in accordance with Cahns linear theory of spinodal decomposition,[1-3] regardless of types of non-solvent additive.

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전뇌허혈 유발 후 침전극저주파자극 적용이 소뇌의 세포자멸사 억제에 미치는 영향 (The Effect of Needle Electrode Electrical Stimulation Following Global Ischemia on the Suppression of Apoptosis in the Cerebellum)

  • 왕중산;박주현;문옥곤;김년준;최정현;김지성
    • 한국전자통신학회논문지
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    • 제8권12호
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    • pp.1949-1958
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    • 2013
  • 본 연구는 온목동맥의 일시적 폐색에 의해 유발된 전뇌허혈로 인해 발생한 SD 랫드 소뇌 부위의 세포자멸사에 대한 침전극저주파자극(Needle Electrode Electrical Stimulation : NEES) 적용의 효과를 알아보기 위하여 면역조직화학적검사법을 통하여 조직을 관찰하였다. 연구를 통하여 대조군과 전뇌허혈유발군, 침전극저주파자극시행군의 세포자멸사 관련 인자의 발현정도를 비교하여 분석한 결과 전뇌허혈 후 침전극저주파의 적용은 SD 랫드 소뇌 부위의 c-fos 발현 감소에 유의한 효과를 보였으며, bax, caspase-3의 발현 감소에는 유의한 영향이 없는 것으로 나타났다. 이상의 결과로 보아 전뇌허혈 후 침전극저주파자극의 적용은 세포자멸사 관련 인자의 발현 억제에 일부분 효과성이 있는 것으로 사료된다.

Health-Related Quality of Life among Breast Cancer Patients and Influencing Factors in Morocco

  • El Fakir, Samira;El Rhazi, Karima;Zidouh, Ahmed;Bennani, Maria;Benider, Abdelatif;Errihani, Hassan;Mellass, Nawfel;Bekkali, Rachid;Nejjari, Chakib
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권12호
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    • pp.5063-5069
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    • 2016
  • Background: Breast cancer is the most common cancer among women in most countries of the world. It is ranked first in females in Morocco (accounting for 33.4% of the total cancer burden) and more than 60% of cases are diagnosed at stage III or IV. During the last decade, health-related quality of life (HRQOL) has become an important aspect of breast cancer treatment. The objective of this study was to describe self-reported HRQOL in patients with breast cancer and to investigate its associations with sociodemographic and clinical variables. Methods: A prospective study was carried out in the main oncology centers in Morocco. Quality of life was measured using the Moroccan Arabic versions of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C 30 (EORTC QLQ C30) and the Breast Cancer-Specific Quality of Life Questionnaire (EORTC QLQ-BR23). Statistical analyses were performed using descriptive statistics and multivariate analyses. Results: A total of 1463 subjects were included in the study, with a mean age of 55.6 (SD. 11.2) years, 70% being married. The majority had stage II (45.9%) and a few cases stage IV (12.9%) lesions. The participants' global health mean score was 68.5 and in "functional scales", social functioning scored the highest (Mean 86.2 (SD=22.7)). The most distressing symptom on the symptom scale was financial difficulties (Mean 63.2 (SD=38.2)). Using the disease specific tool, it was found that future perspective scored the lowest (Mean 40.5 (SD=37.3)). On the symptom scale, arm symptoms scored the highest (Mean 23.6 (SD=21.6)). Significant mean differences were noted for many functional and symptom scales. Conclusion: Our results emphasized that the general HRQOL for our study population is lower than for corresponding populations in other countries. This study provided baseline information on the quality of life for a large sample of Moroccan women diagnosed with breast cancer.

Quality of Life and Psychological Well-Being of Breast Cancer Survivors in Jordan

  • Abu-Helalah, Munir;Al-Hanaqta, Motasem;Alshraideh, Hussam;Abdulbaqi, Nada;Hijazeen, Jameel
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권14호
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    • pp.5927-5936
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    • 2014
  • Introduction: Breast cancer is the most common cancer among Jordanians. Breast cancer patients suffer from several negative consequences after treatment and these include pain, fatigue, sexual problems, appearance and body image concerns, with psychological dysfunction. This could affect the patient quality of life and psychological well-being. To the best of our knowledge, there is no published quantitative data on the quality of life and psychological well-being of breast cancer patients in Jordan. The objective of this study was to obtain such data and assess predictors with calculated scores. Methods: In this cross-sectional study conducted among breast cancer patients in Jordan diagnosed in 2009 and 2010, assessment was performed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), the Breast Module (QLQ-BR23) and the Hospital Anxiety and Depression Scale (HADS). Clinical, demographic and psychosocial indicators that could predict patient quality of life scores were collected. Results: The number of patients interviewed was 236 (mean age=$50.7{\pm}10.7$ years). The mean Global Health score for the QLQ-C30 was $63.7{\pm}20.2$ SD. Among functional scales, "social functioning" scored the highest ($mean=78.1{\pm}28.6$ SD), whereas "emotional functioning" scored the lowest ($mean=59.0{\pm}SD\;33.5$). For the QLQ-BR23, the worst scores within the functional scales were for "body image" ($mean=52.1{\pm}36.8$ SD) and "future perspective" ($mean=52.9{\pm}38.5$ SD). The worst symptom was "upset by hair loss" ($mean=69.8{\pm}43.0$). The mean HADS scores was $18.{\pm}9.0$ SD. Out of study participants, 53% scored abnormal on the anxiety scale and 45% on the depression scale. Severe depression and severe anxiety were detected among 8% and 14% of study participants, respectively. Statistically significant predictors for individual scores were similar to those reported in published studies, such as the presence of recurrence since baseline, family history of cancer, low educational status, current social problems, extent of the disease, presence of financial difficulties, and employment status. Conclusions and Recommendations: Breast cancer survivors in Jordan have overall good quality of life scores when compared with patients from Western countries. However, their psychological wellbeing is more impaired. There is an urgent need for psychosocial support programs and psychological screening and consultation for breast cancer patients at hospitals of the Ministry of Health in Jordan.

Full HD TV를 위한 효율적인 VDP SoC 구조 (Effective SoC Architecture of a VDP for full HD TVs)

  • 김지훈;김영철
    • 스마트미디어저널
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    • 제1권1호
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    • pp.1-9
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    • 2012
  • 본 논문에서는 Full HD TV를 위한 화질 개선 VDP( Video Display Processor)의 SoC( System on a Chip) 구현을 위한 효율적인 하드웨어 구조를 제안한다. 제안한 구조는 SoC 설계의 한 방법으로써 효율적인 버스 구조와 유연성 있는 인터페이스를 지원하여 실시간 비디오 처리를 가능하게 한다. VDP를 구성 하고 있는 비디오 IP 들은 고화질 영상 제공 및 화질 개선을 위한 목적으로 설계 되었고, 각각의 IP는 실시간성 보장 및 SoC의 하드웨어 통합을 위해서 Avalon 인터페이스가 사용되었다. 이는 설계시간을 단축하고, IP 검증과 특히 SoC를 구성하는데 있어서 IP 추가 삭제 및 변경 등이 용이함으로써 사용자의 편리성을 높여준다. 또한 SoC의 임베디드 소프트웨어는 실시간으로 비디오 세부 항목 설정 및 데이터 전송 방식 설정 등을 제어할 수 있음으로써 유연성 있는 실시간 처리 시스템을 구현할 수 있다. VDP의 SoC 구현은 CyclonIII SoPC(System on a Programmable Chip) 플랫폼 상에서 구현되었으며, 실험 결과 SD 해상도의 입력 영상을 Full HD 해상도로 변환시킴으로써 고화질 영상을 획득 할 수 있다.

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