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http://dx.doi.org/10.13067/JKIECS.2013.8.11.1949

The Effect of Needle Electrode Electrical Stimulation Following Global Ischemia on the Suppression of Apoptosis in the Cerebellum  

Wang, Joong-San (여주대학교 물리치료과)
Park, Joo-Hyun (수원여자대학교 물리치료과)
Moon, Ok-Kon (군장대학교 물리치료과)
Kim, Nyeon-Jun (포항대학교 물리치료과)
Choi, Jung-Hyun (남서울대학교 물리치료학과)
Kim, Ji-Sung (수원여자대학교 물리치료과)
Publication Information
The Journal of the Korea institute of electronic communication sciences / v.8, no.12, 2013 , pp. 1949-1958 More about this Journal
Abstract
This study conducted observation of tissues using the immunohistochemistry methods in order to see the effect of Needle Electrode Electrical Stimulation(: NEES) on apoptosis in the SD rat cerebellum caused by global ischemia which came from common carotid artery occlusion. The comparison and analysis results of expression of factors related to apoptosis among the control group, the global ischemia group and the NEES group showed that NEES following global ischemia had a significant effect on the reduction of c-fos expression in the SD rat cerebellum, and didn't have a significant effect on the reduction of bax and caspase-3 expression. In conclusion, it is considered that NEES following global ischemia is partially effective in suppressing the expression of factors related to apoptosis.
Keywords
Common Carotid Artery Occlusion; Global Ischemia; Apoptosis; Needle Electrode Electrical Stimulation;
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Times Cited By KSCI : 3  (Citation Analysis)
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