• 한국동물위생학회지
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• 제34권1호
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• pp.5-12
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• 2011

Infectious bursal disease (IBD) caused by infectious bursal disease virus (IBDV) is a highly contagious viral disease in chicken. It causes heavy economic loss by immune suppression and high mortality. The IBDV, designated Avibirnavirus in the Family Birnaviridae, has a double-stranded RNA genome formed by two segments, segment A and segment B. Segment A encodes a 108 KDa polypeptide that is self-cleaved to produce pVP2, VP3 and VP4, and later pVP2 is cleaved to VP2. The VP2 contains the antigenic regions responsible for elicitation of neutralizing antibodies and VP3 is a major immunogenic protein of IBDV. In this study, monoclonal antibodies (MAbs) specific for IBDV were produced and characterized. All 15 MAbs were specific for IBDV and did not react with other viruses used in this study. The protein specificity of MAbs was determined by comparing the reactivity patterns of each MAb with IBDV VP2 and VP234 recombinant baculoviruses and Western blot analysis. As a result, 7 MAbs (1F5, 2C8, 2F4, 3C7, 4C3, 6F11, 6G5) and 5 MAbs (2A4, 2G2, 3F5, 3G2, 4F10) were specific for VP2 and VP3, respectively. The protein specificity of 3 MAbs (2B8, 3F7, 3F8) were not determined. Five (2C8, 2F4, 4C3, 6F11, 6G5) of the VP2-specific MAbs had a neutralizing activity against IBDV. Some MAbs reacted with IBDV-infected bursa of Fabricius by indirect fluorescence antibody (IFA) and immunohistochemistry (IHC) assay. The MAbs produced in this study would be used for diagnostic reagents for the detection of IBDV infection.

• 한국잡초학회지
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• 제9권2호
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• pp.149-153
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• 1989

Allelopathy 작용성(作用性)을 나타내는 4종(種)의 잡초(雜草) 중에 존재(存在)하는 휘발성(揮發性) terpene 물질(物質)을 GC 및 GC-MS로 동정(同定)하였다. 쑥에서는 26종(種)의 휘발성(揮發性) terpene 류(類)를 분리(分離) 동정(同定)하였는데 이들은 monoterpene 16종(種)과 sesquiterpene 10종(種)이었다. 또한 토끼풀에서는 4종(種), 쇠비름과 냉이에서 각(各) 3종(種)이 확인(確認)되었다. 동정(同定)된 terpene 중 allelopathy 작용성(作用性)을 나타내는 물질(物質)로는 쑥에서 ${\alpha}$-phellandrene, 1,8-cineole, limonene, ${\beta}$-pinene, borneol, selinene 및 caryophyllene, 토끼풀에서 ${\alpha}$-pinene과 ${\beta}$-caryophyllene, 그리고 냉이에서 ${\alpha}$-pinene 등이었고, 쇠비름 중에는 allelopathy 작용성(作用性)을 나타내는 휘발성(揮發性) terpene 류(類)는 없는 것으로 나타났다.

• Parasites, Hosts and Diseases
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• 제58권1호
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• pp.37-46
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• 2020

Livestock husbandry is vital to economy of the Tarim Basin, Xinjiang Autonomous Region, China. However, there have been few surveys of the distribution of ixodid ticks (Acari: Ixodidae) and tick-borne pathogens affecting domestic animals at these locations. In this study, 3,916 adult ixodid ticks infesting domestic animals were collected from 23 sampling sites during 2012-2016. Ticks were identified to species based on morphology, and the identification was confirmed based on mitochondrial 16S and 12S rRNA sequences. Ten tick species belonging to 4 genera were identified, including Rhipicephalus turanicus, Hyalomma anatolicum, Rh. bursa, H. asiaticum asiaticum, and Rh. sanguineus. DNA sequences of Rickettsia spp. (spotted fever group) and Anaplasma spp. were detected in these ticks. Phylogenetic analyses revealed possible existence of undescribed Babesia spp. and Borrelia spp. This study illustrates potential threat to domestic animals and humans from tick-borne pathogens.

• 한국식품저장유통학회지
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• 제13권6호
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• pp.726-731
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• 2006

식물 추출물들의 어유에 대한 항산화력을 rancimart test, 과산화물가, TBA, DPPH 소거능을 이용하여 알아보고자 하였다. 44종 식물추출물을 1,000 ppm 첨가한 어유를 선 실험하여 대조구보다 induction period가 약 $1.5{\sim}3.1$배 증가된 결과를 보인 추출물 7종을 선별하여 주된 실험 시료로 사용하였다. 농도별(100, 200, 300, 500, 700, 1,000 ppm) rancimat test 결과 감자 추출물이 가장 연장된 induction period를 보였으며 붉나무는 첨가량에 따른 높은 증가율을 보였다. 과산화물가와 IBA에서 감자와 붉나무의 항산화력이 보였으며, DPPH 소거능에서는 붉나무의 활성이 높게 나타났다.

• 혜화의학회지
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• 제10권1호
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• pp.337-364
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• 2001

Clinically the arthritis occupies much part of musculoskeletal diseases. The arthritis is subordinate to Bi-jeung in the oriental medicine. No matter what is the cause of the diseases, the lesions of the arthritis are mostly cartilages and bursa. But in process of the depravation bones, muscles, tendons, ligaments and blood are influenced and become new the lesions of the arthritis. it is important that the treatments of the oriental medicine must be objectified and we must absorb a good of the western medical treatments and understand the excellent study of the arthritis in the western medicine. This study was done to comply a reference of 56 master's theses on the cartilage of the western medicine. And these theses were classified by the college, time, treatments and topics. The following results were obtained in this study: 1. Whereas In the theses on the cartilages of the western medicine, Jung-ang and Catholic university have the more theses than any other universities. 2. Analysing the theses on the cartilages of the western medicine, we can classify them by the topics with the influence on the regeneration and culture of the cartilages, observation of the historical structure and the influence on the cartilages by the operation. 3. The theses of the influence on the regeneration and culture of the cartilages were the most, 48%, and the seceond was the influence on the cartilages by the operation.(22%) However the theses on the observation of the historical structure occupied 16%.

• 한국동물위생학회지
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• 제34권4호
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• pp.353-359
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• 2011

Fowl cholera is a contagious acute and chronic disease caused by Pasteurella multocida in both domesticated and wild birds. Acute fowl cholera in both chickens and wild birds has recently been documented in Korea, but the chronic form has not been reported in Korea until now. This study describes the first outbreak of chronic fowl cholera in 13-week-old Arbor Acre broiler breeder chickens submitted to the College of Veterinary Medicine, Kyungpook National University in April 2006. The clinical signs of the affected flock of 9,621 chickens were lameness caused by swollen hock joints, diarrhea, ruffled feathers, and an average weekly mortality of 1.0%. At necropsy, purulent or caseous exudates were found in the hock and wing joints, humerus, and eyes, and severe pneumonia and pericarditis were discovered. Eleven bacterial isolates obtained from the liver, joint, infraorbital sinus and sternal bursa of the submitted chickens were all identified as Pasteurella multocida based on their physiological and biochemical characteristics. Five isolates were examined for antimicrobial susceptibility against 21 different antimicrobial agents including ampicillin. All were resistant to kanamycin, neomycin, and streptomycin, and some were resistant to gentamicin. The tested isolates were all susceptible to the other 17 antimicrobial agents. All 11 isolates were capsular serogroup A based on multiplex polymerase chain reaction. In addition, two of five isolates used in the antimicrobial susceptibility test were identified as somatic serotype 1 by an agar gel diffusion precipitin test, while the others were non-typable.

• 대한정형도수물리치료학회지
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• 제13권1호
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• pp.67-72
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• 2007

Anatomy: The rotator cuff comprises four muscles-the subscapularis, the supraspinatus, the infraspinatus and the teres minor-and their musculotendinous attachments. The subscapularis muscle is innervated by the subscapular nerve and originates on the scapula. It inserts on the lesser tuberosity of the humerus. The supraspinatus and infraspinatus are both innervated by the suprascapular nerve, originate in the scapula and insert on the greater tuberosity. The teres minor is innervated by the axillary nerve, originates on the scapula and inserts on the greater tuberosity. The subacromial space lies underneath the acromion, the coracoid process, the acromioclavicular joint and the coracoacromial ligament. A bursa in the subacromial space provides lubrication for the rotator cuff. Etiology: The space between the undersurface of the acromion and the superior aspect of the humeral head is called the impingement interval. This space is normally narrow and is maximally narrow when the arm is abducted. Any condition that further narrows this space can cause impingement. Impingement can result from extrinsic compression or from loss of competency of the rotator cuff. Syndrome: Neer divided impingement syndrome into three stages. Stage I involves edema and/or hemorrhage. This stage generally occurs in patients less than 25 years of age and is frequently associated with an overuse injury. Generally, at this stage the syndrome is reversible. Stage II is more advanced and tends to occur in patients 25 to 40 years of age. The pathologic changes that are now evident show fibrosis as well as irreversible tendon changes. Stage III generally occurs in patients over 50 years of age and frequently involves a tendon rupture or tear. Stage III is largely a process of attrition and the culmination of fibrosis and tendinosis that have been present for many years. Treatment: In patients with stage I impingement, conservative treatment is often sufficient. Conservative treatment involves resting and stopping the offending activity. It may also involve prolonged physical therapy. Sport and job modifications may be beneficial. Nonsteroidal anti - inflammatory drugs(NSAIDS) and ice treatments can relieve pain. Ice packs applied for 20 minutes three times a day may help. A sling is never used, because adhesive capsulitis can result from immobilization.

• 대한족부족관절학회지
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• 제6권2호
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• pp.261-264
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• 2002

Purpose: To investigate the clinical features of fistulas of the ankle joints. Materials and Methods: Seven fistulas in seven patients were reviewed during Apr. 2000 to Mar. 2002, retrospectively. There are five men and two wemen. Average age was 47.7 years (range, 42-65 years). Average follow-up period was 1.4 years. There were six cystic lesions after ankle sprain and one patient with persistent discharge after excision of bursa over lateral malleolus. Results: Duration from injury to presentation was average 9.8 years. The site of preoperative swelling was mostly over the lateral malleolus in five patients. In one patient, the area of swelling was extended to the anterolateral ankle joint and in another patient there was extensive swelling from Achilles tendon to the anterolateral ankle joint. Concomitant symptoms were instability in three patients, pain and instability in three patients. Methods of surgery were simple repair in one, modified Brostrom in three, augmentation with periosteal flap in addition to modified Brostrom in two and Chrisman-Snook in addition to augmentation with periosteal flap and modified Brostrom in one. There were no recurrence of instability as well as fistula. Conclusion: We think that the fistula of the ankle joint should be included in the differential diagnosis of the cystic lesion over the lateral malleolus and the result of surgical treatment would be satisfactory in most cases.

• Restorative Dentistry and Endodontics
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• 제45권3호
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• pp.40.1-40.12
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• 2020

Objectives: The aim of this study was to evaluate the effects of endodontic treatment on levels of substance P (SP) and calcitonin gene-related peptide (CGRP) in the saliva of patients with symptomatic apical periodontitis. Materials and Methods: Twelve patients with mandibular molars with symptomatic apical periodontitis were enrolled in this study. An initial saliva sample was collected just before administration of anesthesia for root canal treatment, which was performed at the first visit. A second saliva sample was collected at a control visit 1 week after treatment. Salivary SP and CGRP levels were evaluated quantitatively using biochemical assays. The data were analyzed using Pearson correlation analysis, the paired samples t-test, and the Mann-Whitney U test (p = 0.05). Results: The postoperative salivary level of SP was significantly lower than the preoperative level (p = 0.005). However, the postoperative salivary level of CGRP was similar to the preoperative level (p = 0.932). Visual analog scale (VAS) scores of patients' subjective pain were found to be positively correlated with salivary levels of SP (r = 0.421; p = 0.040). No statistically significant correlations were observed between salivary levels of CGRP and VAS scores for patients' subjective percussion tenderness (p = 0.533) or VAS scores for patients' subjective pain (p = 0.459). Conclusions: According to the results of the present study, salivary SP levels may be used as an objective indicator in the diagnosis and assessment of the degree of pain in endodontic diseases.

• 대한관절경학회지
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• 제14권3호
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• pp.192-195
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• 2010

상완골두의 전상방부와 전방 오구견봉 궁 사이의 비정상적인 접촉으로 인해 발생되는 오구돌기하 충돌증후군은 견관절 전방부 동통을 유발하는 비교적 드문 질환이다. 이는 견관절부의 수술적 치료로 인해 오구돌기와 소결절 사이의 해부학적 관계가 변형되어 견갑하근과 점액낭을 포함한 주변 연부조직의 충돌을 유발 하게 된다. 저자들은 오구돌기 골절을 유관나사를 이용해 고정한 환자에서 오구돌기하 공간의 협소화로 인해 견갑하건 파열을 동반하는 오구돌기하 충돌증후군을 경험하였다. 관절경하에서 유관나사 제거 및 견갑하건 봉합 시행 후 술전 환자의 증상은 소실되었다. 오구돌기하 충돌증후군은 견관절 수술 후 지속적 견관절 동통을 유발하는 원인 중의 하나가 될 수 있다.