References
- Stashenko P, Teles R, D'Souza R. Periapical inflammatory responses and their modulation. Crit Rev Oral Biol Med 1998;9:498-521. https://doi.org/10.1177/10454411980090040701
- Caviedes-Bucheli J, Munoz HR, Azuero-Holguin MM, Ulate E. Neuropeptides in dental pulp: the silent protagonists. J Endod 2008;34:773-788. https://doi.org/10.1016/j.joen.2008.03.010
- Siqueira JF Jr, Rocas IN, Favieri A, Machado AG, Gahyva SM, Oliveira JC, Abad EC. Incidence of postoperative pain after intracanal procedures based on an antimicrobial strategy. J Endod 2002;28:457-460. https://doi.org/10.1097/00004770-200206000-00010
- Steinhoff M, Stander S, Seeliger S, Ansel JC, Schmelz M, Luger T. Modern aspects of cutaneous neurogenic inflammation. Arch Dermatol 2003;139:1479-1488. https://doi.org/10.1001/archderm.139.11.1479
- Caviedes-Bucheli J, Rojas P, Escalona M, Estrada A, Sandoval C, Rivero C, Lombana N, Munoz HR. The effect of different vasoconstrictors and local anesthetic solutions on substance P expression in human dental pulp. J Endod 2009;35:631-633. https://doi.org/10.1016/j.joen.2008.12.020
- Roosterman D, Goerge T, Schneider SW, Bunnett NW, Steinhoff M. Neuronal control of skin function: the skin as a neuroimmunoendocrine organ. Physiol Rev 2006;86:1309-1379. https://doi.org/10.1152/physrev.00026.2005
- Peters EM, Ericson ME, Hosoi J, Seiffert K, Hordinsky MK, Ansel JC, Paus R, Scholzen TE. Neuropeptide control mechanisms in cutaneous biology: physiological and clinical significance. J Invest Dermatol 2006;126:1937-1947. https://doi.org/10.1038/sj.jid.5700429
- N'Diaye A, Gannesen A, Borrel V, Maillot O, Enault J, Racine PJ, Plakunov V, Chevalier S, Lesouhaitier O, Feuilloley MG. Substance P and calcitonin gene-related peptide: key regulators of cutaneous microbiota homeostasis. Front Endocrinol (Lausanne) 2017;8:15.
- Fischer HP, Eich W, Russell IJ. A possible role for saliva as a diagnostic fluid in patients with chronic pain. Semin Arthritis Rheum 1998;27:348-359. https://doi.org/10.1016/S0049-0172(98)80014-0
- Lee YH, Wong DT. Saliva: an emerging biofluid for early detection of diseases. Am J Dent 2009;22:241-248.
- Li Y, Denny P, Ho CM, Montemagno C, Shi W, Qi F, Wu B, Wolinsky L, Wong DT. The Oral Fluid MEMS/NEMS Chip (OFMNC): diagnostic and translational applications. Adv Dent Res 2005;18:3-5. https://doi.org/10.1177/154407370501800102
- Nicolodi M, Del Bianco E. Sensory neuropeptides (substance P, calcitonin gene-related peptide) and vasoactive intestinal polypeptide in human saliva: their pattern in migraine and cluster headache. Cephalalgia 1990;10:39-50. https://doi.org/10.1046/j.1468-2982.1990.1001039.x
- Borelli V, Marchioli A, Di Taranto R, Romano M, Chiandussi S, Di Lenarda R, Biasotto M, Zabucchi G. Neuropeptides in saliva of subjects with burning mouth syndrome: a pilot study. Oral Dis 2010;16:365-374. https://doi.org/10.1111/j.1601-0825.2009.01648.x
- Zidverc-Trajkovic J, Stanimirovic D, Obrenovic R, Tajti J, Vecsei L, Gardi J, Nemeth J, Mijajlovic M, Sternic N, Jankovic L. Calcitonin gene-related peptide levels in saliva of patients with burning mouth syndrome. J Oral Pathol Med 2009;38:29-33. https://doi.org/10.1111/j.1600-0714.2008.00721.x
- Haririan H, Andrukhov O, Bottcher M, Pablik E, Wimmer G, Moritz A, Rausch-Fan X. Salivary neuropeptides, stress, and periodontitis. J Periodontol 2018;89:9-18.
- Cao YQ, Mantyh PW, Carlson EJ, Gillespie AM, Epstein CJ, Basbaum AI. Primary afferent tachykinins are required to experience moderate to intense pain. Nature 1998;392:390-394. https://doi.org/10.1038/32897
- Sabbadini E, Berczi I. The submandibular gland: a key organ in the neuro-immuno-regulatory network? Neuroimmunomodulation 1995;2:184-202. https://doi.org/10.1159/000097197
- Lembeck F, Holzer P. Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation. Naunyn Schmiedebergs Arch Pharmacol 1979;310:175-183. https://doi.org/10.1007/BF00500282
- Mashaghi A, Marmalidou A, Tehrani M, Grace PM, Pothoulakis C, Dana R. Neuropeptide substance P and the immune response. Cell Mol Life Sci 2016;73:4249-4264. https://doi.org/10.1007/s00018-016-2293-z
- De Felipe C, Herrero JF, O'Brien JA, Palmer JA, Doyle CA, Smith AJ, Laird JM, Belmonte C, Cervero F, Hunt SP. Altered nociception, analgesia and aggression in mice lacking the receptor for substance P. Nature 1998;392:394-397. https://doi.org/10.1038/32904
- Bessac BF, Jordt SE. Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control. Physiology (Bethesda) 2008;23:360-370. https://doi.org/10.1152/physiol.00026.2008
- Gunthorpe MJ, Benham CD, Randall A, Davis JB. The diversity in the vanilloid (TRPV) receptor family of ion channels. Trends Pharmacol Sci 2002;23:183-191. https://doi.org/10.1016/S0165-6147(02)01999-5
- Ekstrom J, Brodin E, Ekman R, Hakanson R, Sundler F. Vasoactive intestinal peptide and substance P in salivary glands of the rat following denervation or duct ligation. Regul Pept 1984;10:1-10. https://doi.org/10.1016/0167-0115(84)90047-8
- de Paula F, Teshima TH, Hsieh R, Souza MM, Nico MM, Lourenco SV. Overview of human salivary glands: highlights of morphology and developing processes. Anat Rec (Hoboken) 2017;300:1180-1188. https://doi.org/10.1002/ar.23569
- Konttinen YT, Hukkanen M, Kemppinen P, Segerberg M, Sorsa T, Malmstrom M, Rose S, Itescu S, Polak JM. Peptide-containing nerves in labial salivary glands in Sjogren's syndrome. Arthritis Rheum 1992;35:815-820. https://doi.org/10.1002/art.1780350717
- Awawdeh LA, Lundy FT, Linden GJ, Shaw C, Kennedy JG, Lamey PJ. Quantitative analysis of substance P, neurokinin A and calcitonin gene-related peptide in gingival crevicular fluid associated with painful human teeth. Eur J Oral Sci 2002;110:185-191. https://doi.org/10.1034/j.1600-0447.2002.21236.x
- Taylor JJ, Preshaw PM. Gingival crevicular fluid and saliva. Periodontol 2000 2016;70:7-10. https://doi.org/10.1111/prd.12118
- Schlereth T, Schukraft J, Kramer-Best HH, Geber C, Ackermann T, Birklein F. Interaction of calcitonin gene related peptide (CGRP) and substance P (SP) in human skin. Neuropeptides 2016;59:57-62. https://doi.org/10.1016/j.npep.2016.06.001
- Albo F, Antonangeli R, Cavazza A, Marini M, Roda LG, Rossi P. Neuropeptide enzyme hydrolysis in allergic human saliva. Peptides 2002;23:185-192. https://doi.org/10.1016/S0196-9781(01)00594-0
- Lundy FT, Salmon AL, Lamey PJ, Shaw C, Linden GJ. Carboxypeptidase-mediated metabolism of calcitonin gene-related peptide in human gingival crevicular fluid--a role in periodontal inflammation? J Clin Periodontol 2000;27:499-505. https://doi.org/10.1034/j.1600-051x.2000.027007499.x
- Ahmad M, Williams J, Al-Abbousi R, Wheater M. Substance P concentration in saliva of patients who report dental pain. J Adv Oral Res 2014;5:1-5.
- Caviedes-Bucheli J, Lombana N, Azuero-Holguin MM, Munoz HR. Quantification of neuropeptides (calcitonin gene-related peptide, substance P, neurokinin A, neuropeptide Y and vasoactive intestinal polypeptide) expressed in healthy and inflamed human dental pulp. Int Endod J 2006;39:394-400. https://doi.org/10.1111/j.1365-2591.2006.01093.x
- Marco B, Alessandro R, Philippe F, Fabio B, Paolo R, Giulio F. The effect of aging on nerve morphology and substance P expression in mouse and human corneas. Invest Ophthalmol Vis Sci 2018;59:5329-5335. https://doi.org/10.1167/iovs.18-24707
- Luthman J, Friskopp J, Dahllof G, Ahlstrom U, Sjostrom L, Johansson O. Immunohistochemical study of neurochemical markers in gingiva obtained from periodontitis-affected sites. J Periodontal Res 1989;24:267-278. https://doi.org/10.1111/j.1600-0765.1989.tb01792.x
- Bartold PM, Kylstra A, Lawson R. Substance P: an immunohistochemical and biochemical study in human gingival tissues. A role for neurogenic inflammation? J Periodontol 1994;65:1113-1121. https://doi.org/10.1902/jop.1994.65.12.1113
- Bender IB. Pulpal pain diagnosis--a review. J Endod 2000;26:175-179. https://doi.org/10.1097/00004770-200003000-00012
- Dawidson I, Blom M, Lundeberg T, Theodorsson E, Angmar-Mansson B. Neuropeptides in the saliva of healthy subjects. Life Sci 1997;60:269-278. https://doi.org/10.1016/S0024-3205(96)00627-3
- Tschoppe P, Wolgin M, Pischon N, Kielbassa AM. Etiologic factors of hyposalivation and consequences for oral health. Quintessence Int 2010;41:321-333.
- Alobaid AS, Cortes LM, Lo J, Nguyen TT, Albert J, Abu-Melha AS, Lin LM, Gibbs JL. Radiographic and clinical outcomes of the treatment of immature permanent teeth by revascularization or apexification: a pilot retrospective cohort study. J Endod 2014;40:1063-1070. https://doi.org/10.1016/j.joen.2014.02.016
- Yazdanfar I, Gutknecht N, Franzen R. Effects of diode laser on direct pulp capping treatment: a pilot study. Lasers Med Sci 2015;30:1237-1243. https://doi.org/10.1007/s10103-014-1574-8
- Marukawa H, Shimomura T, Takahashi K. Salivary substance P, 5-hydroxytryptamine, and gamma-aminobutyric acid levels in migraine and tension-type headache. Headache 1996;36:100-104. https://doi.org/10.1046/j.1526-4610.1996.3602101.x