• BMB Reports
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• 제49권2호
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• pp.99-104
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• 2016

The nuclear non-histone protein high mobility group box (HMGB) 1 is known to having an inhibitory effect on the repair of DNA damaged by the antitumor drug cisplatin in vitro. To investigate the role of HMGB1 in living cells, we studied the DNA repair of cisplatin damages in mouse fibroblast cell line, NIH-3T3. We evaluated the effect of the post-synthetic acetylation and C-terminal domain of the protein by overexpression of the parental and mutant GFP fused forms of HMGB1. The results revealed that HMGB1 had also an inhibitory effect on the repair of cisplatin damaged DNA in vivo. The silencing of HMGB1 in NIH-3T3 cells increased the cellular DNA repair potential. The increased levels of repair synthesis could be "rescued" and returned to less than normal levels if the knockdown cells were transfected with plasmids encoding HMGB1 and HMGB1 K2A. In this case, the truncated form of HMGB1 also exhibited a slight inhibitory effect.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2005년도 학술발표회(2)
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• pp.1338-1339
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• 2005

• Journal of Species Research
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• 제6권2호
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• pp.195-205
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• 2017

Zubovskya morii (Bey-Bienko, 1931) was rediscovered from its type locality, Mount Baekdusan, from materials collected by Bulgarian zoological expeditions to North Korea in the 1970s. This grasshopper species is endemic to North Korea and for the past 85 years was known only from a single holotype male. In the present study we describe the female Z. morii for the first time. A revised checklist of Orthoptera at Mount Baekdusan (also known as Changbaishan in China) is also provided. A new synonymy, Zubovskya longifurcula (Jin et al., 2011), syn. nov. for Zubovskya koreana Mistshenko, 1952 is proposed here.

• 한국분말야금학회:학술대회논문집
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• 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part 1
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• pp.561-562
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• 2006

The effect of chemical composition of the sintering atmosphere on density, microstructure and mechanical properties of Fe-3%Mn-(Cr)-(Mo)-0.3%C steels is described. Pre-alloyed Astaloy CrM and CrL, ferromanganese and graphite were used as the starting powders. Following pressing in a rigid die, compacts were sintered at 1120 and $1250^{\circ}C$ in atmospheres having different $H_2/N_2$ ratio and furnace cooled to room temperature. It has been found that the atmosphere composition has negligible effect on the as-sintered properties of the investigated materials.

• 대한수학회지
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• 제53권5호
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• pp.1077-1100
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• 2016

We develop an invariant local theory of Lorentz surfaces in pseudo-Euclidean 4-space by use of a linear map of Weingarten type. We find a geometrically determined moving frame field at each point of the surface and obtain a system of geometric functions. We prove a fundamental existence and uniqueness theorem in terms of these functions. On any Lorentz surface with parallel normalized mean curvature vector field we introduce special geometric (canonical) parameters and prove that any such surface is determined up to a rigid motion by three invariant functions satisfying three natural partial differential equations. In this way we minimize the number of functions and the number of partial differential equations determining the surface, which solves the Lund-Regge problem for this class of surfaces.

• The Plant Pathology Journal
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• 제26권3호
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• pp.293-293
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• 2010

• Journal of Microbiology and Biotechnology
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• 제25권4호
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• pp.439-447
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• 2015

The objective of this study was to isolate and identify the chemical structure of a biosurfactant produced by Nocardia farcinica strain BN26 isolated from soil, and evaluate its in vitro antitumor activity on a panel of human cancer cell lines. Strain BN26 was found to produce glycolipid biosurfactant on n-hexadecane as the sole carbon source. The biosurfactant was purified using medium-pressure liquid chromatography and characterized as trehalose lipid tetraester (THL) by nuclear magnetic resonance spectroscopy and mass spectrometry. Subsequently, the cytotoxic effects of THL on cancer cell lines BV-173, KE-37 (SKW-3), HL-60, HL-60/DOX, and JMSU-1 were evaluated by MTT assay. It was shown that THL exerted concentration-dependent antiproliferative activity against the human tumor cell lines and mediated cell death by the induction of partial oligonucleosomal DNA fragmentation. These findings suggest that THL could be of potential to apply in biomedicine as a therapeutic agent.

• 대한정형도수물리치료학회지
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• 제29권1호
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• pp.41-52
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• 2023

Background: Bulgarian split squat (BSS) is beneficial to improve dynamic balance ability and muscle activity of lower extremities, however its effects have not been fully investigated. Therefore, this study aimed to compare changes in dynamic balance ability and muscle properties according to various modifications of BSS exercises. Methods: Thirty healthy male volunteers participated in this study, and they were randomly divided into three different groups. The subjects performed the BSS exercise either on a stable surface with the eyes opened (n=10) or eyes closed (n=10), and on an unstable support plane with eyes opened (n=10) conditions, respectively. Dynamic balance ability was measured via Biodex balance system under the eyes-opened and closed conditions. Additionally, muscle properties of the rectus femoris (RF), vastus medialis (VM) and vastus lateralis (VL) were evaluated. Results: Dynamic balance ability did not show the significant differences among the groups that performed the BSS exercises. However, in the Unstable group, there were significant differences in the overall stability index and anterior posterior stability index under the eyes-closed condition between pre-exercise and post-exercise. In comparison of muscle properties according to the groups, RF muscle showed a significant difference in amount of change of elasticity (p=.038). Additionally, there were significant changes in post measurements of VM muscle tone (p=.016), stiffness (p=.012) and elasticity (p=.002). VL muscle, however had no significant differences in muscle properties. Conclusion: These results indicate that BSS exercises could induce the alteration of RF and VM muscle properties, in particular VM muscle which is susceptible to weakness. Thus, BSS could be applied in various ways as an effective rehabilitation exercise.

• Mycobiology
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• 제29권3호
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• pp.145-153
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• 2001

The mycoflora of Korea was rather poorly studied in the past and the fungi belonging to the genus Septoria are no exception. For this reason, taxonomic studies on Septoria have been initiated, with the eventual aim of producing a monograph of the Septoria species present in Korea. The present study circumscribes 10 species; viz., Septoria artemisiae, S. callistephi, S. chrysanthemella, S. erigerontis, S. lycopersici, S. lysimachiae, S. oenotherae, S. phlogis, S. rohlenae, and S. sonchi. Distinguishing morphological characters are described and illustrated for each species.

• 호남수학학술지
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• 제41권2호
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• pp.321-328
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• 2019

We completely characterize the isomorphic class of those associative unitary rings whose elements are sums of four commuting idempotents. Our main theorem enlarges results due to Hirano-Tominaga (Bull. Austral. Math. Soc., 1988), Tang et al. (Lin. & Multilin. Algebra, 2019), Ying et al. (Can. Math. Bull., 2016) as well as results due to the author in (Alban. J. Math., 2018), (Gulf J. Math., 2018), (Bull. Iran. Math. Soc., 2018) and (Boll. Un. Mat. Ital., 2019).