• 대한전자공학회논문지TC
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• 제40권7호
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• pp.261-272
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• 2003

Ethernet PON(Passive Optical Network)은 최근 활발하게 연구되고 있는 경제적이고 효율적인 가입자망이다. 차세대 가입자망인 Ethernet PON의 MAC(Media Access Control) 프로토콜은 TDMA(Time Division Multiple Access)방식을 기본으로 하며, QoS(Qualify of Service)를 보장해야 하는 전용회선(Leased Line) 가입자에 적합한 고정 할당 방식과 LAN/MAN의 최선형(Best Effort) 방식에 적합한 동적 할당 방식으로 나눌 수 있다. 본 논문에서는 이들 프로토콜의 성능을 분석하기 위하여 OPNET 시뮬레이션 도구를 이용해 Ethernet PON 모델을 설계한다. 설계된 모델에 대한 단대단 Ethernet 지연(end-to-end Ethernet delay), 큐잉 지연(queuing delay), 처리(throughput)과 사용률(utilization) 분석을 통해서 MAC 프로토콜을 검증하고, 하나의 OLT(Optical Line Terminal)가 수용할 수 있는 최적의 ONU(Optical Network Unit) 개수를 산정한다. 또한, 적정한 ONU의 버퍼 크기를 제안하여 Ethernet PON의 망 효율을 극대화하는 방안을 제시한다.

• BMB Reports
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• 제34권5호
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• pp.402-407
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• 2001

Based on the currently proposed toxicity model for the different Bacillus thuringiensis Cry $\delta$-endotoxins, their pore-forming activity involves the insertion of the ${\alpha}4-{\alpha}5$ helical hairpin into the membrane of the target midgut epithelial cell. In this study, a number of polar or charged residues in helix 4 within domain I of the 65-kDa dipteranactive Cry11A toxin, Lys-123, Tyr-125, Asn-128, Ser-130, Gln-135, Arg-136, Gln-139 and Glu-141, were initially substituted with alanine by using PCR-based directed mutagenesis. All mutant toxins were expressed as cytoplasmic inclusions in Escherichia coli upon induction with IPTG. Similar to the wild-type protoxin inclusion, the solubility of each mutant inclusion in the carbonate buffer, pH 9.0, was relatively low When E. coli cells, expressing each of the mutant proteins, were tested for toxicity against Aedes aegypti mosquito-larvae, toxicity was completely abolished for the alanine substitution of arginine at position 136. However, mutations at the other positions still retained a high level of larvicidal activity Interestingly, further analysis of this critical arginine residue by specific mutagenesis showed that conversions of arginine-136 to aspartate, glutamine, or even to the most conserved residue lysine, also abolished the wild-type activity The results of this study revealed an important determinant in toxin function for the positively charged side chain of arginine-136 in helix 4 of the Cry11A toxin.

• 한국경영과학회지
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• 제37권4호
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• pp.211-223
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• 2012

This study purposed to evaluate the influences of rival hospitals on the number of patients who visited the a study territory hospital. Spatial analysis technique was used to measure the impact of rival hospitals in study region. Selected hospitals were all medical school affiliated hospitals which were located in Daejeon metropolitan city and Chungchungnamdo. Patient data was collected from the claims data of the study hospital, and the number of inpatient and outpatients who visited the study hospital between January and June in 2008 were calculated on the smallest administrative district, Eup, Myeon, and Dong, in study region. To control the differences of regional characteristics among Eup, Myeon, Dong, socio-economic variables (total population, number of people aged over 65, number of basic livelihood security recipients, distance from the study hospital to the centroid point of each Eup, Myeon, Dong, number of business, and number of employees) were included in analysis model. These variables were collected from the annual year book of city as well as county located in study region. Cluster analysis classified the study region into three groups by using the difference of between th actual number of inpatient/outpatient and the predicted number of inpatient/outpatient in Eup, Myeon, and Dong. Most areas around the rivalry hospitals were categorized into same group. Multiple regression analysis indicated that areas around rivalry hospitals had statistically significantly negative relationship with the number of inpatients and outpatients who visited the study hospital. As the buffer size was increased from 5Km to 10Km, the standardized regression coefficients were decreased. These study results confirmed that rivalry hospitals in region had negative impacts on the performance of hospitals. It suggests that hospitals will require not only to select their location to minimize the effects of rivalry hospitals, but also to establish their strategy to cope with the rivalry's threats in their region.

• 한국식품영양과학회지
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• 제22권5호
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• pp.570-575
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• 1993

양조간장 분말을 Sephadex 겔 여과 크로마토그래피법으로 분획한 후, 가장 갈색도가 높은 melanoidin 관련 물질의 획분인 melanoidin related products(MRPs)을 모아 동결 건조시킨 다음, 이의 free redical scavenger 기능, 항산화 효력상승제의 기능과 금속 킬레이터로서의 기능, 리폭시게나아제 활성 저해능, 그리고 저장안전성 등에 대한 항산화 특성을 고찰한 결과 다음과 같다. MRPs는 첨가농도(혹은 갈색도)의 증가에 따라 과산화물의 생성을 저해하였으며, 그 항산화력은 ${\alpha}-토코페롤$ 보다는 낮았다. 그리고 free redical scavenger로서의 능력을 가지고 있어 리놀레산 혼합물의 산호를 지연 시켰으며, 염화제일철에 의하여 촉매된 산화반응에서 synergistic antioxidative effect를 나타내었다. 또한 양조간장 MRPs는 리폭시게나아제 활성을 저해하여 conjugated dienoic acid 생성량을 감소시켰다. 한편, 이 MRPs는 저장 안전성이 상당히 있어, $50^{\circ}C$에서 15일간 저장되어 있어도 항산화 효과의 상실이 거의 없음이 관찰되었다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2010년도 제39회 하계학술대회 초록집
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• pp.139-139
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• 2010

Ionic Transition Metal Complex based (iTMC) Light-emitting electrochemical cells (LEECs) have been drawn attention for cheap and easy-to-fabricate light-emitting device. LEEC is one of the promising candidate for next generation display and solid-state lighting applications which can cover the defects of current commercial OLEDs like complicated fabrication process and strong work-function dependent sturucture. We have investigated the performance characteristics of LEECs based on poly (3, 4-ethylenedioxythiophene):poly (styrene sulfonate) (PEDOT:PSS)-incorporated transition metal complex, which is tris(2, 2'-bipyridyl)ruthenium(II) hexafluorophosphate in this study. There are advantages using conductive polymer-incorporated luminous layer to prevent light disturbance and absorbance while light-emitting process between light-emitting layer and transparent electrode like ITO. The devices were fabricated as sandwiched structure and light-emitting layer was deposited approximately 40nm thickness by spin coating and aluminum electrode was deposited using thermal evaporation process under the vacuum condition (10-3Pa). Current density and light intensity were measured using optical spectrometer, and surface morphology changes of the luminous layer were observed using XRD and AFM varying contents of PEDOT:PSS in the Ruthenium(II) complex solution. To observe enhanced ionic conductivity of PEDOT:PSS and luminous layer, space-charge-limited-currents model was introduced and it showed that the performances and stability of LEECs were improved. Main discussions are the followings. First, relationship between film thickness and performance characteristics of device was considered. Secondly, light-emitting behavior when PEDOT:PSS layer on the ITO, as a buffer, was introduced to iTMC LEECs. Finally, electrical properties including carrier mobility, current density-voltage, light intensity-voltage, response time and turn-on voltages were investigated.

• 폴리머
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• 제25권1호
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• pp.108-114
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• 2001

Krebs회로 산인 L-malic acid와 glycerol의 -OH와 -COOH의 몰비를 달리하면서 가교공중합체 poly(glycerol-co-malate)s를 합성하였다. 단량체 및 합성된 가교공중합체를 적외선흡수 분광기법에 의하여 확인하였으며, pH에 따른 수팽윤도를 측정하였다. 용액의 pH가 증가함에 따라 그 공중합체 수화겔의 수팽윤도는 증가하였으며, 각 pH에서 가교공중합체는 -COOH에 대한 -OH기의 몰비가 증가할수록 수팽윤도가 감소하였다. 용액의 pH 변화에 따른 가교공중합체의 가수분해도를 37${\circ}C$에서 조사한 결과 용액의 pH가 증가함에 따라 가수분해는 빨리 진행되었다. 모델 약물로는 diclofenac monosodium salt를 사용하여 pH에 따른 약물방출 거동을 조사한 결과 약물의 방출은 pH가 증가할수록 더 빨리 방출되었고, 합성된 가교공중합 에스테르는 미반응 카르복실기와 하이드록실기로 인해 pH에 의해 크게 영향을 받음을 확인하였다.

• 한국정보처리학회논문지
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• 제7권4호
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• pp.1211-1216
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• 2000

ATM은 패킷 데이터 서비스 통신에 적합한 통신방식으로 데이터, 음성, 영상 등의 서비스를 동시에 지원할 수 있다. 이러한 ATM의 QoS를 보증하기 위해서는 패킷 데이터를 전송하는 소스 비율에 대해 네트워크 초과적조 조건을 조절하는 것이 필요하는데 대부분의 제어알고리즘이 임계값을 기반으로 한 피드백 제어방식이다. 그러니 실시간 음성 트레픽과 같은 서비스는 네트워크 상에서 데이터 서비스 동안에 동적인 연결이 설정되고 종료될 수 있으므로 피드벡 제어정보가 지연된다면 고속으로 서비스된 음성 데이터에 대한 품질은 소스의 목적지 사이의 시간 지연으로 인해 손실될 수 있다. 본 논문에서는 제시된 최소평균제곱오차에 근거를 둔 제어 알고리즘은 예시적인 피드백 제어로 피드백 제어를 위해 미지함수의 기울기와 버퍼크기를 이용하여 미래의 버퍼크기를 예측하려 하였으며 시뮬레이션 질과 본 논문에서 제시한 제어 알고리즘은 효과적임이 증명되었다.

• 농촌계획
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• 제14권1호
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• pp.59-71
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• 2008

The landscape commonly refers to the appearance of the land, including its shape, texture, and colours. Among many factors contributing to the landscape, tree and plants factors playa significant role in rural landscape as a colours. Therefore the rural traditional theme village where had been designated under the rural traditional theme village since 2007 in Naegok-ri, Eohang-myeon, Haman-gun has planned to design the tree plant planning for creating a unique rural landscape. The landscape proposal for the new Rural Village in Naegokri, Yeohang-myeon, Haman-gun suggests three main strategies; 1) The riverside area and reservoir area adjoined forest was required to be prepared to offer organization waterside landscape and forest landscape through landscape planting and selecting trees i.e. able to reflect sense of the season that promote high quality values of landscape area in rural. 2) The area adjoined stable was required to strengthen the screen planting and buffer planting with multiple plant layer structure and trees of branches and leaves closeness, shrubs of beauty flowers in order to improve disamenity landscape and odours. 3) The rural traditional theme village adjoined entrance was required to open space such as multipurpose garden, specialized or themed garden which include Landmark factors and prepared to the space with the various theme and visual diversity in order to take charge of function as landmark characteristic in Naegok-ri, Eohang-myeon, Haman-gun, and so on. In conclusion, this winning principal purpose of this study is applied to basic tree plant model for sustainable rural landscape creation in rural areas by selecting beautiful landscape plants and the tree plant planning.

• 인터넷정보학회논문지
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• 제3권3호
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• pp.87-93
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• 2002

복잡한 통신망과 병렬컴퓨터에서는 효율적인 상호 연결을 위해 스위치가 중요한 영향을 미친다. 이 스위치는 라우팅 정보에 따라서 입력포트와 출력포트 사이에 연결을 해주는 역할을 하게 된다. 따라서 스위치에 성능을 향상시키는 것은 중요한 일이다. 본 논문에서 제안한 스위치는 컴퓨터 시뮬레이션 결과 입력버퍼형 보다 최대처리율이 11%이상 향상되었고, 다른 반얀형 스위치들에 비하여 성능과 하드웨어 양을 비교하여 볼 때 좋은 결과를 얻었다. 따라서 이 스위치는 VLSI 칩으로 구현될 경우 초고속 ATM-LAN 과 병렬컴퓨터를 개발하는데 유용하게 활용될 수 있을 것이다. 제안된 반얀형 스위치는 MAX$＋^+$PLUSII, VHDL을 이용하여 설계 및 검증을 하고 시뮬레이션을 하였다

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1998년도 Proceedings of UNESCO-internetwork Cooperative Regional Seminar and Workshop on Bioassay Guided Isolation of Bioactive Substances from Natural Products and Microbial Products
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• pp.191-191
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• 1998

It has been hypothesized that formation of oxygen-derived free radicals may play an important part in ischemically induced tissue injury. In this study, the effects of vitamin C treatment on hepatic reperfusion model were investigated. Livers isolated from 18 hrs fasted rats were subjected to low flow hypoxia (1 $m\ell$/g liver/min, for 45min) followed by reoxygenation (for 30min). The perfusion medium used was Krebs-Henseleit bicarbonate buffer (KHBB, pH 7.4) and vitamin C (0.25, 0.5, 1.0 and 2.0 mM) was added to perfusate. 7-Ethoxycoumarin was used as substrate of phase and metbolism. After hypoxia oxygen consumption significantly dropped but vitamin C 0.25, 0.5 and 1.0 mM treatments restored oxygen consumption to the level of control group. LDH and lipid peroxidation were not changed in all experimental groups. Oxidation, phase metabolism, significantly decreased following hypoxia but improved during reoxygenation. Vitamin C 0.25 mM treatment significantly improved the oxidation of 7-ethoxycoumarin during hypoxia and reoxygenation, but the oxidation significantly decreased by vitamin C 2.0 mM treatment. Similarly, sulfate conjugation decreased in hypoxic group, but this decrease was inhibited by vitamin C 0.25, 0.5 and 1.0 mM treatments. Our findings suggest that hypoxia/reoxygenation diminishes hepatic drug metabolizing function, vitamin C at concentration of 0.25-1.0 mM ameliorates but at higher concentration aggravates these hypoxia/reoxygenation-induced changes.