• 제목/요약/키워드: Bronchial Neoplasms

검색결과 42건 처리시간 0.022초

기관지선종의 수술요법 (surgical treatment of bronchial adenoma -Report of 6 cases-)

  • 서동만;김주현
    • Journal of Chest Surgery
    • /
    • 제17권1호
    • /
    • pp.129-132
    • /
    • 1984
  • Bronchial Adenomas are rare entity among the primary bronchopulmonary neoplasms. But they have received attention because of debate on their malignant nature, prognosis, and mode of therapy. We have four carcinoids and two cylindromas from Jan. 1972 to Jun. 1983. Operations include two pneumonectomies two lobectomies and one bilobectomy. In one cylindroma, resection was impossible due to its invasion into mediastinum and pericardium. There were no hospital deaths.

  • PDF

다발성 원격전이를 보인 비정형 기관지 유암종 1예 (A Case of atypical bronchial carcinoid with multiple distant metastasis)

  • 이태헌;양성욱;이태관;김병구;김지영;김귀완;이광민
    • Tuberculosis and Respiratory Diseases
    • /
    • 제43권3호
    • /
    • pp.440-448
    • /
    • 1996
  • Bronchial carcinoid tumors are uncommon, constituting approximately 3-5% of all primary lung cancers. Classification of these tumors has evolved substantially as our understanding of the cellular, biologic, and clinical aspects of these neoplasms has improved. Initially, bronchial carcinoids were thought to be benign and therefore were classified as bronchial adenomas. Currently, however, they are well recognized as having the potential for both local invasion and distant metastatic involvement. Consequently, carcinoid tumors are frankly malignant. Thus bronchial adenoma is a misnomer that should no longer be used for bronchial carcinoids. Most investigators currently favor classifying carcinoid tumors as a type of neuroendocrine neoplasm because of their potential to secrete a variety of chemical substances found in both the central nervous system and the epithelial cells of numerous organs. Bronchial carcinoids are usually characterized by a slow growth pattern and a low incidence of metastasis, and histologically conformed by the azurophil staining and the presence of the characteristic neurosecretary granule on electron microscopy. Atypical carcinoid tumor was first defined by Arrigoni et al, who proposed the following criteria for separation of atypical carcinoid from typical carcinoid tumor : 1) increased mitotic activity with 1 mitotic figure per 1-2 high power fields(or 5-10 mitoses /10 HPF), 2) nuclear pleomorphism, hyperchromatism, and an abnormal nuclear-cytoplasmic ratio, 3) areas of increased cellularity with disorganization of the architecture, and 4) tumor necrosis. In contrast, typical carcinoid tumor may have focal cytologic pleomorphism, but necrosis is absent and mitotic figures are rare. Recently we experienced a case of atypical bronchial carcinoid with multiple distant metastasis, so we report this case with a review of the literature.

  • PDF

비소세포성 폐암으로 인한 기관지 림프절 누공 1예 (A Case of Node-bronchial Fistula by Non-small Cell Lung Cancer)

  • 김서우;김현경;전승정;박혜성;장중현;이진화;류연주;심성신;천은미
    • Tuberculosis and Respiratory Diseases
    • /
    • 제68권4호
    • /
    • pp.231-235
    • /
    • 2010
  • Lymphadenopathy in the thoracic cavity is frequently caused by inflammatory diseases. In very rare cases, the node-bronchial fistula has been reported to be the cause of complications of pulmonary tuberculosis. A male patient with necrotizing pneumonia and mediastinal lymph node enlargements identified by chest computed tomography was also found to have a node-bronchial fistula caused by lung cancer. The patient was treated for tuberculosis with pneumonia for one week before a definitive diagnosis was made. A further investigation revealed him to have non-small cell lung cancer (NSCLC, adenocarcinoma) and multiple mediastinal lymphadenopathies accompanied with the node-bronchial fistula. We report this specific case that had been previously treated for tuberculosis but was later revealed to be NSCLC accompanied with a node-bronchial fistula.

주변부 폐암에서 기관지세척액을 이용한 MAGE유전자검사법의 임상적 유용성 (MAGE Gene Expression in Bronchial Washing Fluid in Suspected Parenchymal Lung Cancer)

  • 김규진;최은영;신경철
    • Tuberculosis and Respiratory Diseases
    • /
    • 제72권2호
    • /
    • pp.156-162
    • /
    • 2012
  • Background: The main goal of this study was to evaluate the diagnostic efficacy of reverse transcription-nested polymerase chain reaction (RT-nested PCR) in bronchial washing fluid with MAGE A1-6 common primers for the detection of lung cancers invisible by bronchoscopy. Methods: To determine the expression of MAGE A1-6 gene in 189 lung cancers diagnosed by conventional fluoroscopy-guided lung biopsy and 89 cancer-free controls, RT-nested PCR was performed in bronchial washing specimens. We analyzed MAGE A1-6 RT-nested PCR data according to tumor histology, stage, size, and compared them with cytological data. Results: 189 patients (111 cases in adenocarcinoma, 47 cases in squamous cell carcinoma, 22 cases in small cell lung carcinoma, and 9 cases in other cancers) and 89 benign patients were investigated. The expression of MAGE was performed by nested RT-PCR using common MAGE primer. Among 189 cancer patients, the expression rate of MAGE was 49.2%, and the positive predictive value was 89.4%. However, the expression rate of MAGE in patients with benign lesions was 12.4%. In peripheral lung cancer, the positive rate of MAGE expression was 57.4% in squamous cell carcinoma, 44.1% in adenocarcinoma and 59.1% in small cell lung cancer. Whereas the expression rate of bronchial washing cytology in peripheral lung cancer was 9.0% (p=0.011). Conclusion: MAGE RT-PCR in bronchial washing fluid gave us promising data for the detection of peripheral lung cancer. It could be a useful method for selecting diagnostic tools for peripheral lesions.

국소 임파절 전이를 동반한 전형적 기관지 유암종 1예 (A Case of Typical Bronchial Carcinoid with Metastasis to Regional Lymph Nodes)

  • 김지훈;신동호;김태화;박성수;이정희;정원상;류근신;고영혜;이중달
    • Tuberculosis and Respiratory Diseases
    • /
    • 제40권1호
    • /
    • pp.67-71
    • /
    • 1993
  • Bronchial carcinoids were classified as one of the bronchial adenoma group and constituted about 90% of bronchial adenoma. Typical carcinoids are common benign neoplasms of the airway because of their uniform histologic feature, predictable clinical course and good survival after surgical resection. And atypical carcinoid is regarded as a malignant tumor because of its pleomorphic, hyperchromatic nucleus, frequent mitosis and distant metastasis (about 70%). However, typical carcinoids rarely metastasize to regional lymph nodes and such cases would be regarded as a low grade malignancy because their clinical prognosis could be bad. We present a case of typical bronchial carcinoid which metastasize to hilar lymph node who has been followed up 10 months after resection.

  • PDF

Cicatricial Fibromatosis Diagnosis after Suspected Local Recurrence at the Bronchial Stump Following Lobectomy for Lung Cancer

  • Hwang, Wan Jin;Lee, Yeiwon;Jung, Soo Young;Yeh, Daewook;Park, Soon Hyo;Yoon, Yoo Sang
    • Journal of Chest Surgery
    • /
    • 제49권2호
    • /
    • pp.134-137
    • /
    • 2016
  • A mass excision surrounding the bronchial stump was performed to exclude malignancy in a 42-year-old man who had undergone a right lower lobectomy for lung cancer. The mass was identified as a cicatricial fibroma. Cicatricial fibromatosis, which is desmoid fibromatosis that arises in a surgical scar, is a well-known clinical condition. It consists of histologically benign neoplasms. Their occurrence after thoracic surgery is extremely rare. Biopsy or excision of suspicious lesions is very important for diagnosis. R0 resection remains the principal outcome for intrathoracic desmoid fibromatosis. We report that a cicatricial fibromatosis in the subcarinal space was removed after suspicion of local recurrence at the bronchial stump follwing lobectomy for lung cancer.

기관지에 발생한 원발성 신경초종-2예 보고- (Primary Schwannoma of Bronchus - 2 case report-)

  • 홍순창;박인규;김대준;정경영
    • Journal of Chest Surgery
    • /
    • 제37권12호
    • /
    • pp.1036-1039
    • /
    • 2004
  • 기관 및 기관지 종양은 대부분이 악성 종양이며 양성 종양은 10% 이내에 불과하다. 특히 폐에 발생하는 원발성 신경성 종양은 전체 폐종양의 2% 이하로 대부분이 Schwann세포에서 기원한다고 알려져 있다. 이러한 종양은 주로 고립성 양성 종양으로 나타나며 드문 경우에 악성의 형태를 보이기도 한다. 기관지내 신경초종은 폐의 원발성 종양 중에서 발생빈도가 매우 낮은 것으로 알려져 있다. 저자들은 기관지내 신경초종으로 폐엽절제술을 시행한 2예를 보고하는 바이다.

Bronchial Carcinoid Tumor Arising from an Intralobar Bronchopulmonary Sequestration

  • Ma, Dae-Sung;Kim, Sun-A;Kim, Hyeong-Ryul;Kim, Yong-Hee;Park, Seung-Il;Kim, Dong-Kwan
    • Journal of Chest Surgery
    • /
    • 제44권6호
    • /
    • pp.444-447
    • /
    • 2011
  • We report a rare case of a 38-year-old woman with a bronchial carcinoid tumor arising from an intralobar bronchopulmonary sequestration. The vascular supply to the sequestered left lower lobe originated from the descending thoracic aorta. A left lower lobe lobectomy was performed. The findings of the pathological examination revealed an atypical carcinoid tumor that was immunopositive for chromogranin and synaptophysin. At the 3-year follow-up examination, the patient was healthy.

우하엽 기관지에서 발생한 점막 표피양 종양의 수술 치험 -1예 보고- (Mucoepidermoid Carcinoma of the Right Lower Lobe Bronchus - A case report-)

  • 김연수;김욱성;장우익;주미;류지윤
    • Journal of Chest Surgery
    • /
    • 제37권11호
    • /
    • pp.955-958
    • /
    • 2004
  • 점막 표피양 선종은 드문 종양으로 원발성 악성 기관지 선종의 1%와 모든 폐종양의 0.2%를 차지한다. 이종양은 기관지 자극이나 폐쇄에 의한 증상을 나타낸다. 원격 전이는 드물기 때문에 완절 절제술이 최선의 치료법이다. 이 종양의 예후는 종양의 조직학적 악성도에 의한다. 저자들은 기침과 피가래의 증상을 보인 15세의 점막 표피양 종양환자를 경험하였다. 환자는 흥부 전산화단층 촬영과 기관지 내시경하 생검 후 개흉술을 시행하여 이엽절제술에 의한 완전한 종양 절제를 받았다.

폐에 전이된 점액표피양 암종의 세포병리학적 소견 (Cytopathology of Metastatic Mucoepidermoid Carcioma of the Lung)

  • 박원서;함의근
    • 대한세포병리학회지
    • /
    • 제5권2호
    • /
    • pp.180-183
    • /
    • 1994
  • A case of metastatic mucoepidermoid carcinoma of the lung, originating from the hard palate, was diagnosed by sputum and bronchial washing cytology. Although the cytologic features of mucoepidermoid carcinoma have been well described, it is easy to confuse mucoepidermoid carcinoma with the more common primary adenocarcinoma or squamous cell carcinoma of the lung. The features distinguishing mucoepidermoid carcinoma from other primary neoplasms include 1) mucus-secreting cells individually and in clusters admixed with other cell components, 2) epidermoid cells identified by the presence of abundant spread-out cytoplasm and an oval dark nucleus and 3) intermediate cells resembling normal ductal epithelial cells with moderate-to-scanty cytoplasm, a central, round vesicular nucleus and a prominent nucleolus. The morphologic features of metastatic mucoepidermoid carcinoma in this case were similar to those of primary salivary mucoepidermoid carcinoma.

  • PDF