• Korean Journal of Radiology
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• 제1권3호
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• pp.127-134
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• 2000

Objective: To determine the extent to which thin-section and volumetric three-dimensional CT can depict airway reactivity to bronchostimulator, and to assess the effect of different airway sizes on the degree of reactivity. Materials and Methods: In eight dogs, thin-section CT scans were obtained before and after the administration of methacholine and ventolin. Cross-sectional areas of bronchi at multiple levels, as shown by axial CT, proximal airway volume as revealed by three-dimensional imaging, and peak airway pressure were measured. The significance of airway change induced by methacholine and ventolin, expressed by percentage changes in cross-sectional area, proximal airway volume, and peak airway pressure was statistically evaluated, as was correlation between the degree of airway reactivity and the area of airways. Results: Cross-sectional areas of the bronchi decreased significantly after the administration of methacholine, and scans obtained after a delay of 5 minutes showed that normalization was insufficient. Ventolin induced a significant increase in cross-sectional areas and an increase in proximal airway volume, while the effect of methacholine on the latter was the opposite. Peak airway pressure increased after the administration of methacholine, and after a 5-minute delay its level was near that of the control state. Ventolin, however, induced no significant decrease. The degree of airway reactivity did not correlate with airway size. Conclusion: Thin-section and volumetric spiral CT with three-dimensional reconstruction can demonstrate airway reactivity to bronchostimulator. The degree of reactivity did not correlate with airway size.

• Tuberculosis and Respiratory Diseases
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• 제55권3호
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• pp.239-249
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• 2003

Multi-detector row CT (MDCT) provides faster speed, longer coverage in conjunction with thin slices, improved spatial resolution, and ability to produce high quality muliplanar and three-dimensional (3D) images. MDCT has revolutionized the non-invasive evaluation of the central airways. Simultaneous display of axial, multiplanar, and 3D images raises precision and accuracy of the radiologic diagnosis of central airway disease. This article introduces central airway imaging with MDCT emphasizing on the emerging role of multiplanar and 3D reconstruction.

• Tuberculosis and Respiratory Diseases
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• 제70권1호
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• pp.10-20
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• 2011

Various diseases can diffusely involve central airways, including the trachea and main stem bronchi. Central airway abnormalities are frequently not apparent or are overlooked on chest radiographs, even though the patient may have significant symptoms. Recent advances in spiral and multi-detector computed tomography (CT) with multi-planar reconstruction and three-dimensional demonstration, including virtual bronchoscopy, allow for excellent display of central airway anatomy and abnormalities with visualization of accurate locations of lesions. Early detection and proper diagnosis of airway diseases based on various radiographic findings will help determine appropriate treatment, including surgical planning and evaluation of treatment response. Herein we describe and illustrate the imaging findings of a wide spectra of diffuse central airway diseases.

• Tuberculosis and Respiratory Diseases
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• 제56권4호
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• pp.343-347
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• 2004

선천성 기관지 폐쇄증은 단순촬영에서 폐 결절로 보여 악성 종양으로 오인될 수 있다. 그러나 흉부단순촬영과 특히 전산화단층촬영에서는 늘어난 기관지 내의 점액고착, 구역 과팽창 등이 특징적으로 보여 더 이상의 침습적 검사 없이 선천성 기관지 폐쇄증으로 진단할 수 있다.

• Journal of Chest Surgery
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• 제22권3호
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• pp.468-472
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• 1989

Bronchogenic cysts are uncommon congenital lesions which are derived from primitive foregut. Most of the bronchogenic cysts may occur at the tracheal bifurcation, both main bronchi, the lung parenchyme and the mediastinum. We experienced a case of bronchogenic cyst with a esophageal stalk. The diagnosis was made by simple chest x-ray and confirmed by bronchoscopy and chest CT. On the chest CT findings, 6.8X4.8 cm-sized oval shaped mass was located on the right posteroinferior side of the carina, elevating the right main bronchus and the thin wall of the mass was enhanced with contrast materials. On the operative findings, the esophagus and the cyst were connected with a stalk and the cyst was filled with mucinous materials. And on the histological findings, the mass was lined with pseudostratified ciliated columnar epithelium. Thus we report this case of bronchogenic cyst with review of literatures.

• Korean Journal of Radiology
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• 제1권3호
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• pp.135-141
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• 2000

Objective: To compare the clinical utility of the different imaging techniques used for the evaluation of tracheobronchial diseases. Materials and Methods: Forty-one patients with tracheobronchial diseases [tuberculosis (n = 18), bronchogenic carcinoma (n = 10), congenital abnormality (n = 3), post-operative stenosis (n = 2), and others (n = 8)] underwent chest radiography and spiral CT. Two sets of scan data were obtained: one from routine thick-section axial images and the other from thin-section axial images. Multiplanar reconstruction (MPR) and shaded surface display (SSD) images were obtained from thin-section data. Applying a 5-point scale, two observers compared chest radiography, routine CT, thin-section spiral CT, MPR and SSD imaging with regard to the detection, localization, extent, and characterization of a lesion, information on its relationship with adjacent structures, and overall information. Results: SSD images were the most informative with regard to the detection (3.95±0.31), localization (3.95±0.22) and extent of a lesion (3.85±0.42), and overall information (3.83±0.44), while thin-section spiral CT scans provided most information regarding its relationship with adjacent structures (3.56±0.50) and characterization of the lesion (3.51±0.61). Conclusion: SSD images and thin-section spiral CT scans can provide valuable information for the evaluation of tracheobronchial disease.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.2393-2398
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• 2012

Objectives: The purpose of this study was to evaluate the geometric accuracy of thoracic anatomic landmarks as target surrogates of intrapulmonary tumors for manual rigid registration during image-guided radiotherapy (IGRT). Methods: Kilovolt cone-beam computed tomography (CBCT) images acquired during IGRT for 29 lung cancer patients with 33 tumors, including 16 central and 17 peripheral lesions, were analyzed. We selected the "vertebrae", "carina", and "large bronchi" as the candidate surrogates for central targets, and the "vertebrae", "carina", and "ribs" as the candidate surrogates for peripheral lesions. Three to six pairs of small identifiable markers were noted in the tumors for the planning CT and Day 1 CBCT. The accuracy of the candidate surrogates was evaluated by comparing the distances of the corresponding markers after manual rigid matching based on the "tumor" and a particular surrogate. Differences between the surrogates were assessed using 1-way analysis of variance and post hoc least-significant-difference tests. Results: For central targets, the residual errors increased in the following ascending order: "tumor", "bronchi", "carina", and "vertebrae"; there was a significant difference between "tumor" and "vertebrae" (p = 0.010). For peripheral diseases, the residual errors increased in the following ascending order: "tumor", "rib", "vertebrae", and "carina"; There was a significant difference between "tumor" and "carina" (p = 0.005). Conclusions: The "bronchi" and "carina" are the optimal surrogates for central lung targets, while "rib" and "vertebrae" are the optimal surrogates for peripheral lung targets for manual matching of online and planned tumors.

• 디지털융복합연구
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• 제16권2호
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• pp.19-26
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• 2018

흉부 CT 영상에서 폐 질환의 진단을 위해서 폐 분할, 폐혈관 분할과 폐 질환 부위에 대한 괴사 세포 비율의 수치적 계산을 제안 하였다. 첫 번째 단계는 흉부 CT 영상에서 3차원 레이블링 기법과 3차원 영역 성장법을 적용하여 폐와 기관지를 분리한다. 두 번째 단계는 폐혈관 분할은 1차 다항식 회귀(Polynomial Regression)를 사용한 변화율을 적용하여 분할한 다음, 잡음 제거를 실시하여 최종의 폐혈관을 분할한다. 세 번째 단계는 2단계 이미지 에서 질환 예상 인자를 발견하고, 괴사 세포의 비율을 계산하는 것이다. 질환 예상인자는 폐에 대해서 3차원 레이블링 기법을 적용하였고, 각 레이블 중심 값을 관측하여 변화가 없는 레이블을 찾는다. 이렇게 찾은 질환 예상 인자는 조영제 투입 전/후 영상을 정합한 뒤, 면적을 비교하면 폐의 괴사 세포 비율을 계산할 수 있다.

• 대한영상의학회지
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• 제82권6호
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• pp.1441-1476
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• 2021

기관-기관지분지는 폐와 전신에 산소 공급을 위한 공기의 통로이며, 다양한 병적 상태들이 이러한 해부학적 부위를 침범할 수 있다. 다중 검출 전산화단층촬영은 다양한 기도 질환들의 진단을 위한 발견 및 특성화에 있어 중요한 역할을 한다. 가상 기관지경 검사나 자동 폐분석과 같은 후처리를 통해 영상 영상검사의 활용이 더욱 높아질 수 있다. 본 임상 화보에서는 벽비후와 기관 내 결절의 형태로 나타나는 다양한 기관지 병변들의 다중 검출 전산화단층촬영에서의 소견 및 고차원적 영상 시각화와 분석 영상을 제공하고자 한다.

• 한국임상수의학회지
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• 제22권4호
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• pp.431-434
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• 2005

A 2-year-old castrated male, Cocker spaniel dog with a history of chronic productive cough for 2 to 3 months and with unsuccessful treatment was referred to Veterinary Medical Teaching Hospital, Seoul National University. On thoracic radiographs, there were alveolar infiltrations at left cranial and right caudal lung fields, and soft-tissue opacity round to oval images at overall lung field. The bronchi were dilated, tortuous and not tapered. Abnormal air was accumulated focally in the caudodorsal lung fields. To scrutinize the soft-tissue opacity image and accumulated air, computed tomography (CT) was done. On CT images, severe cylindrical or tubular bronchiectasis was confirmed. And the soft-tissue opacity images were found in the dilated bilated and thought to complexes of mucous plugs, inflammatory cells, necrotic and fibrotic tissue. The dog was dead next day to the CT scan, so necropsy and histopathologic examination were perfermed. On the histopathology, there were cylindrical bronhiectasis and severe diffuse chronic fibrinous necropurulent bronchitis and bronchopneumonia. In this case, it was difficult to diagnose the bronchiectasis only with radiography due to the concurrent lesions, such as pulmonary infiltrations and mucous plugs, which was identified by computed tomography. Thus, computed tomography is considered as a useful modality to confirm tile bronchiectasis camouflaged by the concurrent lesion.