• Title/Summary/Keyword: Breath analysis

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Exhaled Breath Analysis of Lung Cancer Patients Using a Metal Oxide Sensor

  • Yu, Joon-Boo;Byun, Hyung-Gi;Zhang, Sholin;Do, Seoung-Hun;Lim, Jeong-Ok;Huh, Jeung-Soo
    • Journal of Sensor Science and Technology
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    • v.20 no.5
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    • pp.300-304
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    • 2011
  • Exhaled breath gases include gases generated in the body. When there is disease in the body, exhalation can include gas components from the disease. If we can find these specific elements through analysis of the exhalation gases, this can be an effective way to diagnose the disease. The lung has a close relationship with exhalation. Lung cancer refers to malignant tumors which originate in the lungs. Exhalation from the lung causes direct jets of gas to be ejected through the mouth and nose, so by analyzing these jets it may be possible to diagnose lung cancer. In our study we attempt to diagnose lung cancer from patient's exhaled gases. Exhalation of lung cancer patients was analyzed using gas chromatography-mass spectroscopy(GC-MS) and the expiratory gas was also measured using a sensor system. The system was designed to use a metal oxide sensor and solid phase micro extraction(SPME) fiber. The GC-MS analysis of the healthy subject's and cancer patient's exhalation gases both showed the presence of decane in the breath of patients with lung cancer. In addition, the results from the sensor system showed significant difference between the lung cancer patients and the healthy subjects.

Assessment of Inhalation Exposure to Volatile Disinfection By-products Associated with Household Uses of Chlorinated Tap Water (가정에서의 수돗물 사용과 관련된 휘발성 염소소독부산물에 대한 흡입노출 평가)

  • 김희갑;김문숙;윤지현
    • Environmental Analysis Health and Toxicology
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    • v.17 no.2
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    • pp.125-133
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    • 2002
  • Volatile disinfection by-products (DBPs) contained in chlorinated tap water are released into household air during indoor activities (showering, cooking, dish -washing, etc.) associated with tap water uses and may cause adverse health effects on humans. Twenty seven subjects were recruited and their homes were visited during the winter of 2002. Tap water, household air, and exhaled breath samples were collected and analyzed for five volatile DBPs (chloroform, bromodichloromethane, dichloroacetonitrile, 1,1 -dichloropropanone and 1,1,1 trichloropropanone). Chloroform was a major DBP found in most samples. Tap water chloroform concentrations were not statistically correlated with its household air concentrations, probably due to individual variability in indoor activities such as showering, cooking, and dish - washing as well as household ventilation. Correlation of breath chloroform concentration with household air chloroform concentration showed its possible use as a biomarker of exposure to household air chloroform. Exposure estimates suggested that inhalation during household stay be a major route of exposure to volatile DBPs and that ingestion of tap water be a trivial contributor to the total exposure in Koreans.

The Effect of Added Mass of Water and Breath Mode in Fluid-Structure Coupled Vibration Analysis (부가질량 효과와 호흡모드를 고려한 구조-유체연성진동해석)

  • Bae, S.Y.
    • Journal of Power System Engineering
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    • v.9 no.4
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    • pp.71-76
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    • 2005
  • Marine structures are often in contact with inner or outer fluid as stern, ballast and oil tanks. The effect of interaction between fluid and structure has to be taken into consideration when we estimate the dynamic response of the structure appropriately. Fatigue damages can also be sometimes observed in these tanks which seem to be caused by resonance. Thin walled tank structures in ships which are in contact with water and located near engine or propeller where vibration characteristics are strongly affected by the added mass of containing water. Therefore it is essentially important to estimate the added mass effect to predict vibration characteristics of tank structures. But it is difficult to estimate exactly the magnitude of the added mass because this is a fluid-structure interaction problem and is affected by the free surface, vibration modes of structural panels and the depth of water. I have developed a numerical tool of vibration analysis of 3-dimensional tank structure using finite elements for plates and boundary elements for fluid region. In the present study, the effect of added mass of containing water, the effect of structural constraint between panels on the vibration characteristics are investigated numerically and discussed. Especially a natural frequencies by the fluid interaction between 2 panels and a breath mode of the water tank are focused on.

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A Study on Foot Shape of Women (성인 여성의 발 형태 분석에 관한 연구)

  • 서추연;석은영
    • Journal of the Korean Home Economics Association
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    • v.41 no.6
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    • pp.1-12
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    • 2003
  • The purpose of this study were to analyze the anthropometric data of feet of Korean women with aging, to categorize the women's foot shapes, and to compare the shoe size according to the foot shapes in order to provide the basic information for more comfortable shoes. Subjects of this study were 181 women over age 20. They were measured with the direct measurement method and the indirect measurement method. 26 items were measured from the right foot and 6 items were taken on foot outline. Factor analysis, cluster analysis, analysis of variance, post-hoc test, and cross tabs were peformed for statistical analysis of the data by SPSS program. There were significant differences in height items, breadth items, girth items, and angle items by subjects' age. The older subjects' feet were wide and thick with big deformity on toes. The arch height of the older ones was low. This implicates that the degree of deformity on toes, the foot ratio, the foot girth, the foot breath and the arch height as well as the foot length are needed to be considered in developing comfortable shoes. Nine foot construction factors were extracted by the factor analysis of anthropometric measurements; foot size factor, heel and instep factor, malleolus lateralis factor, malleolus medialis factor, foot shape factor, shape of toes factor, heel height factor, big toe height factor, and internal factor. On the basis of the cluster analysis, three different foot shapes were categorized. Type 1 was large and wide foot with little deformity on little toe. Type 2 was medium foot with deformation of big toe, and with the lowest arch height. Type 3 was small and narrow foot with the highest arch height. Distribution of shoe size according to the foot shape was analyzed. The ball of foot breath was of wide distribution than the ball of foot girth. This implicates that girth items and breath items of the foot should be enclosed for the same foot length in the shoe sizing system.

The Effects of Entrance Examination Stress on Oral Health Behavior and Subjective Oral Health in Female High School Students

  • Chung, Kyung-Yi
    • Journal of dental hygiene science
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    • v.20 no.3
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    • pp.126-135
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    • 2020
  • Background: The purpose of this study is to investigate the effects of entrance exam stress on oral health behaviors and subjective oral health status in female high school students. Methods: A self-reported questionnaire was administered to 216 female high school students in the Gwangju area. We performed an independent t-test, one-way analysis of variance (ANOVA), Pearson's correlation coefficient, and multiple regression analysis using the SPSS/WIN 21.0 program. Results: The average of the entrance exam stress was 2.73, and among the sub-areas, the tension for exam/poor stress was the highest with 3.21. As a result of analysis of general characteristics and subjective oral health status, oral mucosal disease was lower in family income level (p<0.05), bad breath was significantly higher with lower academic performance (p<0.001) and family income level (p<0.05). As a result of oral health behavior and subjective oral health status analysis, dental caries has more than 4 times of caries snacks (per week) (p<0.05), bad breath was found to be more perceived when the average number of daily brushing was 2 or less (p<0.01). Factors affecting subjective oral health status were that dental caries was a patients pressure stress (β=0.202); temporomandibular disorder (β=0.227), xerostomia (β=0.342), and oral mucosal disease (β=0.190) were insufficient spare time; bad breath was academic performance (lower) (β=0.231) and insufficient spare time (β=0.184). There was a statistically significant positive correlation between the subjective oral health status and the subarea of entrance exam stress, excluding future uncertainty stress. Conclusion: It is considered that oral health education should be conducted to prevent oral diseases for students with high parental pressure and insufficient spare time stress as well as finding practical ways to reduce entrance stress.

Study on changes in Ryodoraku test according to carbon monoxide concentration in exhaled breath (호기 중 일산화탄소 농도에 따른 양도락 상의 변화 연구 (후향적 증례연구))

  • Koo, Jin Suk
    • The Journal of Korean Medicine
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    • v.41 no.1
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    • pp.45-54
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    • 2020
  • Objectives: The aim of this study was to investigate relationships between Ryodoraku and carbon monoxide concentration during expiration of smokers. This study was designed as an exploratory observational study. This study was based on the hypothesis that increased levels of carbon monoxide in the smoker's breath may affect indicators that reflect the respiratory and circulatory systems in the Ryodoraku test. Methods: The participants were 49 people who smoked for over a year. They were examined at least one hour after their last smoking. They were tested in a stable state. When examining carbon monoxide during expiration, they breathed deeply, kept breathing for 20 seconds, and slowly exhaled. The Ryodoraku test was performed on its representative points of twelve meridians. Pearson's correlation analysis was used to investigate correlation between the concentration of carbon monoxide in the breath and the current in the measurement points. Results: The higher the carbon monoxide concentration in the exhalation, the significantly greater the current value of Lt H1·both H2·Lt H3·Rt H5, deviation of Lt H1·Lt H2·Lt H3 current value and the laterality between right and left current of H3. Conclusion: The more cigarette smoked, the more changes in heart, lung, pericardium and triple energizer meridians were observed in the Ryodoraku test. I found that increased carbon monoxide in smokers could affect the results of the Ryodoraku test.

A study on characteristics to territorial among awareness of halitosis (영역별 특성에 따른 구취 자각정도와 인지에 관한 조사 연구)

  • Park, Sung-Suk;Suh, Eun-Ju;Jang, Gye-Won
    • Journal of Korean society of Dental Hygiene
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    • v.8 no.4
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    • pp.127-139
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    • 2008
  • The purpose of this study was to examine the awareness of people in general about halitosis. The subjects in this study were 184 people who visited the clinical practice lab at J health college to get their teeth scaled. After a survey was conducted from May 1 to June 3, 2008, the analyzable answer sheets from 178 respondents were analyzed after four different areas were selected, which included smoking/nonsmoking, scaling experience, toothbrushing frequency and the use of oral hygiene supplies. SPSSWIN 12.0 program was utilized to make a frequency analysis and crosstabs analysis. The findings of the study were as follows: 1. Concerning subjective feelings of halitosis, 55.3 percent(99 people) of the respondents found themselves to have a moderate level of bad breath. 28.5 percent(51) deemed themselves to have a little foul breath, and 14 percent(25) didn't feel they had any bad breath. 2. As to the subjective level of halitosis, 89.8 percent(168) thought that their bad breath was a little perceived only by themselves, regardless of smoking, scaling experience, toothbrushing frequency and the use of oral hygiene supplies. 3. In regard to the cause of halitosis, 31 percent(56) cited plaque in the mouth as the cause, and 28.5 percent(51) pointed out the other causes that weren't mentioned in the questionnaire. 18.4 percent(33) cited decayed tooth, and 11.2 percent(20) pointed out gastroenteric disorder. 10.6 percent(19) viewed diabetes as the cause. 4. As to the time when they had the subjective symptom of halitosis, 114 respondents(63.7%) felt their own bad breath the most immediately after they got up 21.8 percent(39 respondents) did it when they were hungry 5.5 percent(9) did that before breakfast, and 4.5 percent(8) did that after having breakfast. 5. Regarding view of how to prevent halitosis, 52.5 percent(94) brushed their teeth frequently 21.2 percent(38) got their teeth scaled on a regular basis at a dentist's office, and 17.9 percent(32) drank water often. The above-mentioned finding seemed to suggest that the respondents weren't well aware of the fact halitosis was a sort of oral and systemic disease. Therefore the development of halitosis prevention and care programs geared toward practice lab visions were required.

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A study on factors relevant to the self-perception of halitosis and the correlation between halitosis and obsessive-compulsive disorders (구취의 자각요인과 강박증에 관한 연구)

  • Lee, Mi-Ra;Kim, Nam-Song;Shim, Jae-Suk
    • Journal of Korean society of Dental Hygiene
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    • v.13 no.2
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    • pp.231-237
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    • 2013
  • Objectives : The purpose of this study to provide preliminary data to effective halitosis control. Methods : A survey was carried out the self-perception of causative factors of halitosis in 98 female college students in Chungnam province. In addition, the levels of oral gas and breath gas were measured by use of the B&B checker, and an analysis was made of the correlation between halitosis and obsessive-compulsive disorder (OCD). Results : 1. Subjective halitosis awareness degree different degree of dryness, 'None', 'some', 'little' people who feel as the 'little fly' (68%), 78.3%, 70% was higher (p<0.05), halitosis interest 'very worried', 'worry', 'normal' person with a' not at all 'to 58.3% higher (p<0.01). 2. In regard to OCD severity, 49.0%, 34.7% and 16.3% were found to be mild, moderate and severe respectively. Halitosis tended to be severe in proportion to OCD severity, which was statistically significant (p<0.05). 3. Oral gas had a positively correlation with breath gas (r=0.329, p<0.01), but had a negative one with OCD severity (r=0.204, p<0.05). Conclusions : Symptoms of oral dryness and halitosis interest were associated with self-perception of halitosis. The levels of oral gas and breath gas were in inverse proportion to OCD severity. Hereat, it needs to analyze psychogenic factors properly as regards the diagnosis or treatment of halitosis.

Dosimetric Comparison of Setup Errors in Intensity Modulated Radiation Therapy with Deep Inspiration Breath Holding in Breast Cancer Radiation Therapy (Deep Inspiration Breath Holding을 적용한 유방암 세기변조방사선치료 시 위치잡이오차 분석을 통한 선량 평가)

  • Ham, Il-Sik;Cho, Pyong-Kon;Jung, Kang-Kyo
    • Journal of radiological science and technology
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    • v.42 no.2
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    • pp.137-143
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    • 2019
  • The aim of this study was analyzed the setup error of breast cancer patients in intensity modulated radiation therapy(IMRT) with deep inspiration breath holding(DIBH) and was analyzed the dose distribution due to setup error. A total of 45 breast cancer cases were performed a retrospective clinical analysis of setup error. In addition, the re-treatment planning was carried by shifting the setup error from the isocenter at the treatment. Based on this, the dose distribution of PTV and OARs was compared and analyzed. The 3D error for small breast group and medium breast group and large breast group were 3.1 mm and 3.7 mm and 4.1 mm, respectively. The difference between the groups was statistically significant(P=0.003). DVH results showed HI, CI for the PTV difference between standard treatment plan and re-treatment plan of 14.4%, 4%. The difference in $D_5$ and $V_{20}$ of the ipsilateral lung was 5.6%, 13% respectively. The difference in $D_5$ and $V_5$ of the heart of right breast cancer patients was 6.8%, 8% respectively. The difference in $D_5$, $V_{20}$ of the heart of left breast cancer patients was 7.2%, 23.5% respectively. In this study, there was a significant association between breast size and significant setup error in breast cancer patients with DIBH. In addition, it was found that the dose distribution of the PTV and OARs varied according to the setup error.

Economical Gas Chamber for In-situ Gas Measurement and Analysis of Gas Response Characteristics according to Sensor Voltage (인시투 가스 측정이 가능한 경제적 가스 챔버 구현 및 센서 전압에 따른 가스 응답 특성 분석)

  • Choi, Yun-Suk;Lee, In Hwan
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.18 no.5
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    • pp.1-8
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    • 2019
  • Breath analysis using a portable device is better than the classical breath analysis system in terms of installation and operation. There is an increasing need to develop cost-effective equipment for testing gas sensors from the viewpoint of functionalities that can be applied applicable to portable devices. In the present study, an economical gas chamber for in-situ gas measurement is implemented with a single gas chamber without using expensive gas storage and control equipment; the gas response characteristics are analyzed using the above-described chamber. The main features of the implemented gas chamber are simple injection procedure, improved gas diffusion, easy measurement and cleaning, support for low-power mode measurement function for portable devices, and open source platform. Moreover, an analysis of gas response characteristics based on changes in sensor voltage show that the sensitivity and 90% response time are affected by the sensor voltage. Furthermore, the sensitivity graph has an inflection point in a specific range. The gas sensor applied in this study showed fast response speed and high sensitivity for sensor voltages of 3.0-3.5 V, regardless of the concentration of acetone gas, the target gas used in this study.