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Dosimetric Comparison of Setup Errors in Intensity Modulated Radiation Therapy with Deep Inspiration Breath Holding in Breast Cancer Radiation Therapy

Deep Inspiration Breath Holding을 적용한 유방암 세기변조방사선치료 시 위치잡이오차 분석을 통한 선량 평가

  • Ham, Il-Sik (Department of Radiological Science, Daegu Catholic University) ;
  • Cho, Pyong-Kon (Department of Radiological Science, Daegu Catholic University) ;
  • Jung, Kang-Kyo (Department of Radiology, Andong Hospital)
  • 함일식 (대구가톨릭대학교 방사선학과) ;
  • 조평곤 (대구가톨릭대학교 방사선학과) ;
  • 정강교 (안동병원 영상의학과)
  • Received : 2019.03.09
  • Accepted : 2019.04.28
  • Published : 2019.04.30

Abstract

The aim of this study was analyzed the setup error of breast cancer patients in intensity modulated radiation therapy(IMRT) with deep inspiration breath holding(DIBH) and was analyzed the dose distribution due to setup error. A total of 45 breast cancer cases were performed a retrospective clinical analysis of setup error. In addition, the re-treatment planning was carried by shifting the setup error from the isocenter at the treatment. Based on this, the dose distribution of PTV and OARs was compared and analyzed. The 3D error for small breast group and medium breast group and large breast group were 3.1 mm and 3.7 mm and 4.1 mm, respectively. The difference between the groups was statistically significant(P=0.003). DVH results showed HI, CI for the PTV difference between standard treatment plan and re-treatment plan of 14.4%, 4%. The difference in $D_5$ and $V_{20}$ of the ipsilateral lung was 5.6%, 13% respectively. The difference in $D_5$ and $V_5$ of the heart of right breast cancer patients was 6.8%, 8% respectively. The difference in $D_5$, $V_{20}$ of the heart of left breast cancer patients was 7.2%, 23.5% respectively. In this study, there was a significant association between breast size and significant setup error in breast cancer patients with DIBH. In addition, it was found that the dose distribution of the PTV and OARs varied according to the setup error.

Keywords

References

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