Objectives : In 2007, a survey of how Kampo was regarded in Japanese clinical practice guidelines (CPGs) was first conducted by the Special Committee for Evidence Based Medicine (EBM), namely the Japan Society for Oriental Medicine (JSOM). A manual for CPG development was also published in 2007 by the Japan Council for Quality Health Care, and the revised edition came out in 2014. The purpose this study is to review the current state in CPGs applied to Kampo after 2007, while focusing on how Kampo products being regarded evidence based branch of medicine by CPG developers. Methods : Sources include the Kampo CPGs website of Japan Society for Oriental Medicine (JSOM) and MINDS (Medical Information Network Distribution Service) website of Japan Council for Quality Health Care. Results : Among the 784 CPGs existing by the end of 2015, 91 CPGs were considered containing descriptions of Kampo. Furthermore, 28 type A Kampo CPG (KCPG) which had quality of evidence and strength of recommendation with references were found. Also, most of type A KCPGs relied on the MINDS Handbook for Clinical Practice Guideline Development that was published in 2007. Conclusions : The number of KCPGs are increasing yearly. However, there is still not much Kampo evidence found in CPGs in Japan. Overall, it could be said that we need to not only make evidence vertically but preach it horizontally well.
Background : Osteoporosis and atrophic cell pattern in Pap smear are frequent findings In postmenopausal women due to loss of ovarian function, The present study attempted to find out possible correlation between morphologic characteristics of Pap smear and osteoporosis. Material & methods: The subjects were 825 women(age from 35 to 80) who had undergone Pap smear and bone mineral density(BMD) at The Korea Association of Health Promotion, Seoul Branch, from March 8 to May 10, 2005. Pap smears from 825 women were reviewed and classified either mature cell pattern or atrophic cell pattern by their cytologic patterns, BMD were measured using LUNAR DPX MdIQ(Minster, Ohio, USA). BMD value of lumbar spine(Ll, L2,L3 and L4) were measured from 825 women and BMD value of proximal region off emur(neck NK, Wards triangle WT, and trochanter TR) were measured from 818 women and their bone status were classified as normal( T-sore:>-1.0), osteopenia (T-score: -l~<-2,5) and osteoporosis(T-score: ≤ -2.5). And age distribution of Pap smear, average T-value andfrequency ofsteoporo-sis of each region of the bone, percentage of osteoporosis of each boneregion by age group and changing pattern of percentage of osteopenia and osteoporosis in certain postmenopausal period were compared between mature and atrophic cell pattern. Results: Pap smears revealed total mature cell pattern 53,9%(445/825) and total atrophic cell pattern 46.1%(380/825), Percentage of mature cell pattern decreased from 98.2%(168/171)under 44 age group to 13,3%(17/128) over 65 age group and mature cell pattern increased from 1.8%(3/171) under 44 age group to 86.7%(111/128) oyer 65 age group. Mean T-value of each region of lumbar spine and femur of mature cell pattern were lower than that of atrophic cell pattern about -1,5. And osteoporosis has noted in atrophic cell pattern showing odds ratio Ll 13.9, L2 15.3, L3 12.0, L4 10,4, UK 6.7, WT 10.9 and TR 4.1.Atrophic cell pattern started to increase after 45 years of age and osteoporosis of a trophic cell pattern started after 55 years of age. During 50 to 64 years of age period, L3, L4 and WT revealed parallel increased of osteopenia and osteoporosis and Ll, L2 revealed decreased of osteopenia and increased of osteoporosis. nia Conclusion: Above findings suggest that atrophic cell pattern of Pap smear precedes osteoporosis about 10 years and one of predictor of osteoporosis.
This experiment has been made to find out the influence of soil bulk density on growth and root development of Populus alba ${\times}$ P. glandulosa in Buyeo-kun, Chungnam. Bulk density and porosity significantly change according to slope position and soil depth and have a significant effect on tree height, DBH, biomass, and the distribution of root development. The results extracted from the experiments are as follows; 1) Bulk density in average changes from $1.17g/cm^3$ (1.05 ~ 1.40) in lower slope position to $1.43g/cm^3$ (1.36 ~ 1.60) in upper slope position, and porosity from 52.65% (55.05 ~ 45.50) in lower slope position to 41.20% (43.81 ~ 37.21) in upper slope position. 2) Bulk density increases significantly with soil depth. 3) Tree height, DBH, and total biomass decrease with bulk density. 4) Foliage, branch, bolewood, bolebark, and root also significantly have a negative correlation with hulk density. 5) Populus alba ${\times}$ P. glandulosa has a shallow root system chiefly distributing only in AI horizon, and critical bulk density is $1.43g/cm^3$. Therefore, slope position, hulk density, and porosity are considered to influence on the growth, biomass, and root development of Populus alba ${\times}$ P. glandulosa.
Bae, Sang Jun;Eum, Hyang Lan;Kim, Byung-Sup;Yoon, Jungro;Hong, Sae Jin
Horticultural Science & Technology
/
v.33
no.2
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pp.233-241
/
2015
Kimchi cabbage 'Choon Gwang' cultivar that was grown in highlands in Gangneung was subjected to predrying, room cooling, and forced air cooling, and then packed with/without 0.02 mm HDPE film to investigate the effect of postharvest treatment on quality characteristics during 8 weeks storage at $2^{\circ}C$ (RH $90{\pm}5%$). Weight loss in forced air cooling and room cooling was lower than 3-4% with 0.02 mm HDPE film liner treatment during storage. However, it was only below 10% in room cooling without liner treatment and forced air cooling without liner treatment led to the highest weight loss, above 15%. Conversely, the control had lower weight loss than the others. SSC was $2-4^{\circ}brix$ for all treatments and there was no difference between postharvest treatments and liner treatments. Color index and firmness both showed no differences with/without 0.02 mm HDPE film and postharvest treatments. In sensory evaluation, forced air cooling with liner treatment was effective, with the highest score, especially in appearance and crispness. After 6 weeks, control kimchi cabbage without liner treatment was damaged seriously in appearance and the internal color had changed to brown. Room cooling and predrying with liner treatment changed the start of internal browning to after 8 weeks storage.
The peroxisome proliferator-activated receptor $\gamma$(PPAR$\gamma$), a member of the steroid/thyroid nuclear hormone receptor suferfamily of ligand-activated transcription factor, is an important regulator of adipocyte gene expression and differentiation. In this studies, we report the identification, characterization, and expression of a Hanwoo PPAR$\gamma$ gene. The PPAR$\gamma$ cDNA sequence of the Hanwoo show strong conservation with the corresponding sequences reported in other species except of three amino acid sequences. The distribution of PPAR$\gamma$ mRNA in various tissues of Korean cattle aged 12 months were investigated using Northern Blot analysis. The highest expression was detected in adipose tissue, more lower expression was detected in colon, small intestine, kidney, lung, while expression was not detected in brain, heart. PPAR$\gamma$ expression was higher in adipose tissue of Korean cattle when aged 30 months than aged 12 months. These results indicated PPAR$\gamma$, regulator adipocyte gene expression and differentiation, related on adipose differentiation in Korean native cattle(HANWOO).
Kim Jong Kwan;Kim Hyoung Soon;Bae Young Chun;Lee Sang Min;Kim Kyung Yo;Joo Jong Cheon
Journal of Physiology & Pathology in Korean Medicine
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v.18
no.4
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pp.1192-1198
/
2004
Sasang Constitutional Medicine is a major branch of Korean Traditional Medicine. The differences of disease susceptibility to be shown in Sasang constitution may be due to genetic factors. Therefore, I examined interrelationship among cerebral infarction (CI), apolipoprotein E (apo E) gene polymorphism, and Sasang constitutional classification. Apo E is a key protein modulating the highly atherogenic apoB containing lipoproteins and is a candidate gene for the development of coronary artery disease (CAD). The ε2 and/or ε4 alleles were the first to be implicated in premature CAD, which resulted in this polymorphism being extensively studied. I investigated the association between apo E genotype and CI by case-control study in a Korean population. I also classified CI patients and control group into groups according to Sasang Constitutional Medicine. 218 CI patients and 379 controls without CI were examined. Apo E genotype was determined by 8% polyacrylamide gel separation after DNA amplification. A frequency of apo E ε3/ε3 in the apo E genotype distribution was higher in the CI patients compared with that in controls. Also, it was widely known that Taeumin was easily attacked with CI, but there was no association between apo E polymorphim and Taeumin. However, the Taeumin constitution did not enhance the relative risk for CI in the subjects with apo E ε2 and/or ε4 alleles. No differences in the apo E genotypes frequencies were observed in the Taeumin compared with that in the other constitutions. In addition, I investigated whether the DD(deletion/deletion) or ID(insertion/deletion) genotype of angiotensin converting enzyme (ACE) gene, a candidate gene for CI, was associated with CI, Taeumin constitution, and apo E polymorphism. As a result, the frequency of Taeumin constitution was significantly higher in CI patients with both apo E ε3/ε4 and ACE ID/DD genotypes than in the remaining Sasang constitutions. In summary, it was concluded that the apo E polymorphism is a major risk factor for CI in Koreans and the ACE ID/DD genotype enhanced the relative risk for CI in the subjects with apo E ε3/ε4 genotype and Taeumin constitution.
Hwang, In-Phil;Choi, Heui-Joo;Roh, Jang-Hoon;Kim, Jin
Tunnel and Underground Space
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v.22
no.3
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pp.173-180
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2012
In this study, diagonal ventilation circuits that are advantageous in air flow direction control were studied. Based on the results of the study, it could be seen that air volumes in diagonal ventilation circuits could also be calculated using numerical formulas or programs if the air volumes and air flow directions to be infused into diagonal branches are determined in advance as with other serial/parallel circuits. To apply the results, design plans for high level radioactive waste repositories applied with diagonal ventilation circuits and parallel ventilation circuits. To compared the each design plans and obtain expected operation results, ventilation network simulations were conducted through the Ventsim program which is a ventilation networking program. Based on the results, in the case of diagonal repositories that was expected to cause great increases in resistance, fan pressure was 1570 pa, total flux was 84 $m^3/s$, fan efficiency was 76.4%, fan power consumption was 181.2 kW and annual fan operating costs were 178,710,838 and thus maximum around 8% differences were shown in pressure and flux values and a difference of around 1.5% was shown in terms of operating costs.
Varietal difference in structural and physical characteristics of rice starch and interrelationships between these starch properties and the physicochemical components of rice grains were investigated for twenty four rice varieties, which were considerably different in amylose content, gelatinization temperature and gel consistency, to obtain the basic informations for diversifying the utility of rice grains and for developing various rice cultivars adaptable to rice food processing. Wave length of maximum absorbance for blue color reaction of starch-I$_2$ complex was 520nm for glutinous rice and 560~600nm for nonglutinous rice. The higher amylose rice showed the longer wave length but there was considerable difference of the wave length among rice materials with similar amylose content. Varietal difference in frequency distribution of debranched starch molecules by isoamylase hydrolysis was largest in amylose fraction, the longest fraction(Fr. I), and was next bigger in intermediate fraction(Int.Fr.) and the ratio between short and long glucose chain of amylopectin fraction(Fr. III /Fr. II). The Fr. III / Fr II ratio was higher in glutinous rice than in nonglutinous one but it was considerably different among nonglutinous rice varieties without any connection with amylose content. The lower alkali digestible rice showed the longer half-hydrolysis time in acid solution. Both soft and hard gel rice varieties in gel consistency test revealed significant varietal difference of 50% acid hydrolysis time. The harder rice in gel consistency exhibited the less frequency of short branch fraction of amylopectin (Fr. III) and the higher amylose content. Twenty four rice varieties were cleary classified by upper two principal components contracted from structural or physical traits of rice starch and some physicochemical properties of rice grain by principal component analysis. The 1st and 2nd principal components can be characterized to components related with amylose and amylopectin structure respectively.
Journal of the Korea Academia-Industrial cooperation Society
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v.9
no.5
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pp.1154-1163
/
2008
DAS and SCADA system are main systems, which operate and manage the power system by using computer and communication technology. But DAS and SCADA have been operated independently in Korea, so there was some time delay in the fault handling and live-line work. To improve that problems, studies on the interface between DAS and SCADA have been needed. From November 2005 to December 2007, the pilot project has been performed in KEPCO's branch offices, as a result, direct method will be applied widely all over the country until 2010 because the operation information of substation users want can be transmitted fast and it is possible to control 43RC directly although the expense for direct method is about 1.3 times larger than that for web method. To improve problems revealed during the pilot project, substation object to object communication method is proposed and interface database automatic generation and interface system diagnosis and logging functions are developed. Interface data point and communication data type are defined, substation single line diagram automatic generation or manual editing function, SCADA monitoring and controlling function, log data managing function are developed in SCADA HMI program. It is expecting to reduce the average time for each outage about 33% and to improve the reliability, efficiency of operation, execution of DAS from automatic load transfer under a fault, and to contribute to export project.
Journal of The Korean Society of Agricultural Engineers
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v.54
no.1
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pp.11-18
/
2012
This study was investigated agricultural water supply system of major agricultural waterway for Gimje canal, Jeongeup canal, Dongjin river conduit of Dongjin river basin. Furthermore, this result will be used for water resources and agricultural demand in Saemangeum reclaimed arable land. Annual precipitation for 5 years in Dongjin river basin was 1,311.7mm. The average discharges in Dongjin river basin was $1,390{\times}10^6\;m^3$ and $1,516{\times}10^6\;m^3$ and $744{\times}10^6\;m^3$ for 2,007 and 2008, respectively. Also, annual average amount of water resources was 1,861${\times}10^6\;m^3$ and $2,279{\times}10^6\;m^3$ and $1,227{\times}10^6\;m^3$ for 2,007 and 2008, respectively. Dongjin river basin water system for the analysis of agricultural water in water resources, runoff, agricultural water demand and usage surveys were analyzed, resulting in the total amount of water due to precipitation of the watershed of the $12.3{\times}10^9\;m^3$ ~$22.8{\times}10^9\;m^3$ and Dongjin River basin in waters flowing discharge is $7.4{\times}10^9\;m^3$~$16.1{\times}10^9\;m^3$, agricultural water demand and usage of each of $6.8{\times}10^9\;m^3$~$6.9{\times}10^9\;m^3$ and $4.9{\times}10^9\;m^3$~$7.1{\times}10^9\;m^3$ compared to the agricultural water demand was more likely. Agricultural water supply system in Dongjin river basin is complex because of devided branches to the main canal and branch canal. In this process, accurately assessment of water usage is very difficult. Therefore, systematic management of water resources and supply of agricultural water supply system to use the terms of the complexity and diversity by considering the appropriate level of agricultural water management systems will be needed. As a result of this study, it can be used water resources assessment in quantity, rational usefulness and basic planning of water resources development for water distribution.
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