• KSII Transactions on Internet and Information Systems (TIIS)
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• v.18 no.9
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• pp.2589-2604
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• 2024

Brain tumors, characterized by uncontrollable cellular growths, are a significant global health challenge. Navigating the complexities of tumor identification due to their varied dimensions and positions, our research introduces enhanced methods for precise detection. Utilizing advanced learning techniques, we've improved early identification by preprocessing clinical dataset-derived images, augmenting them via a Generative Adversarial Network, and applying an Improved Privacy-Preserving Collaborative Convolutional Neural Network (IPC-CNN) for segmentation. Recognizing the critical importance of data security in today's digital era, our framework emphasizes the preservation of patient privacy. We evaluated the performance of our proposed model on the Figshare and BRATS 2018 datasets. By facilitating a collaborative model training environment across multiple healthcare institutions, we harness the power of distributed computing to securely aggregate model updates, ensuring individual data protection while leveraging collective expertise. Our IPC-CNN model achieved an accuracy of 99.40%, marking a notable advancement in brain tumor classification and offering invaluable insights for both the medical imaging and machine learning communities.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.11 no.3
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• pp.253-259
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• 2017

Conventional upper extremity rehabilitation paradigm after brain injury has several shortcomings that is monotonous, simple, and repetitive in exercises over a long period of time, thereby causing training efficiency to decline as a consequence of low interest and participation. To resolve this issue, this paper proposes a new rehabilitative program integrating a wearable device integrated with EMG and motion sensor and a mobile game for the upper limbs' rehabilitative training. The developed wearable device is manufactured in the form of band, making it easy to wear. The mobile game is designed to enable rehabilitative training through games reflective of flexion, extension, abduction, and adduction identified by motion sensors along with grasp motion recognized by EMG signals measured from the wearable device. It also provides a tailored rehabilitative environment suitable for individual patients based on difficulty adjustments. As a consequence of applying the developed program to 14 brain injury in need of the upper limb rehabilitation and taking surveys on the utility of the developed rehabilitative program, the responses indicated that the developed rehabilitative program is far much more interesting and fun than the conventional rehabilitative program, further to the desire of those surveyed to reuse the developed program in the future.

• Parasites, Hosts and Diseases
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• v.48 no.1
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• pp.15-21
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• 2010

Astrocytes are the most abundant cells in the central nervous system that play roles in maintaining the blood-brain-barrier and in neural injury, including cerebral malaria, a severe complication of Plasmodium falciparum infection. Prostaglandin (PG) $D_2$ is abundantly produced in the brain and regulates the sleep response. Moreover, $PGD_2$ is a potential factor derived from P. falciparum within erythrocytes. Heme oxygenase-1 (HO-1) is catalyzing enzyme in heme breakdown process to release iron, carbon monoxide, and biliverdin/bilirubin, and may influence iron supply to the P. falciparum parasites. Here, we showed that treatment of a human astrocyte cell line, CCF-STTG1, with $PGD_2$ significantly increased the expression levels of HO-1 mRNA by RT-PCR. Western blot analysis showed that $PGD_2$ treatment increased the level of HO-1 protein, in a dose- and time-dependent manner. Thus, $PGD_2$ may be involved in the pathogenesis of cerebral malaria by inducing HO-1 expression in malaria patients.

• Speech Sciences
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• v.9 no.4
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• pp.237-252
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• 2002

MIT has been applied for nonfluent aphasic patients on the basis of lateralization of brain hemisphere. However, its applications for different languages have some inquiry for aphasic patients because of prosodic and rhythmic differences. The purpose of this study is to develop the Korean Melodic Intonation Therapy program using personal computer and its clinical effects for nonfluent aphasic patients. The algorithm was composed to voice analog signal, PCM, AMDF, Short-time autocorrelation function and center clipping. The main menu contains pitch, waveform, sound intensity and speech files on window. Aphasic patients' intonation patterns overlay on selected kMIT patterns. Three aphasic patients with or without kMIT training participated in this study. Four affirmative sentences and two interrogative sentences were uttered on CSL by stimulus of ST. VOT, VD, Hold and TD were measured on Spectrogram. In addition, articulation disorders and intonation patterns were evaluated objectively on spectrogram. The results indicated that nonfluent aphasic patients with kMIT training group showed some clinical effects of speech intelligibility based on VOT, TD values, articulation evaluation and prosodic pattern changes.

• Journal of Korean Biological Nursing Science
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• v.15 no.2
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• pp.65-73
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• 2013

Purpose: The purpose of this study was to review the literature on music intervention for neurological patients in Korea and to explore the effect of music intervention on functional rehabilitation of neurological patients. Methods: This systematic review examined literature from 2005 to 2010. The existing literature was searched in the electronic databases of RISS and KISS using the following keywords: music, rhythmic movement, stroke, brain injury, dementia, Parkinson, spinal cord injury. Seventy-seven studies were founded through the database. After The exclusion of duplicates, case studies, literature review, and irrelevant studies, nine studies were included for analysis. Results: They included nine quasi-experimental studies. The medical diagnoses of the study participants were stroke, dementia, brain injury, and spinal cord injury. Among nine studies, only two studies were conducted in the nursing area. Eight studies used comprehensive music programs composed of health education, gait training, vocal training, or relaxation therapy, and these comprehensive programs were effective in the areas of physical and psychosocial treatment. Seventeen sessions were provided on average throughout intervention, and the average duration of each session was 49.4 minutes. Conclusion: Comprehensive music intervention can be implemented in nursing care for patients with neurological problem.

• Clinical Psychopharmacology and Neuroscience
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• v.16 no.4
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• pp.391-397
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• 2018

Objective: Meditation can elicit trait-like changes in psychological and social styles, as well as enhancement of emotional regulatory capacity. We investigated the relation between personality traits and emotional intelligence in meditation practitioners. Methods: Seventy-two long-term practitioners of mind-body training (MBT) and 62 healthy comparative individuals participated in the study. The participants completed emotional intelligence questionnaires and the Myers-Briggs Type Indicator (MBTI). Results: The MBT group revealed higher scores on all five emotional intelligence factors than did those in the control group, such as emotional awareness and expression, empathy, emotional thinking, emotional application, and emotional regulation (all $p{\leq}0.001$). MBT practitioners also had higher scores on the intuition of perceiving function (t=-2.635, p=0.010) and on the feeling of the judging function (t=-3.340, p=0.001) of the MBTI compared with those in the control group. Only the MBT group showed a robust relationship with every factor of emotional intelligence and MBTI-defined intuitive styles, indicating that higher scores of emotional intelligence were related to higher scores for intuition. Conclusion: Emotional intelligence of meditation practitioners showed notable relationships with some features of personality trait. In-depth associations between emotional intelligence and personality traits would help to foster psychological functions in meditation practitioners.

• 한국노년학
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• v.28 no.4
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• pp.925-940
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• 2008

As the proportion of old people in contemporary societies steadily increases, the influence on cognitive rehabilitation strategy of the memory deficit associated with normal and pathological aging grows greater as well. This paper reviewed the current memory rehabilitation techniques for older adults. In the first part of this article, human memory systems as a framework for understanding memory aging were considered. In the second part, research findings concerning memory performance in normal aging and Alzheimer's disease were reviewed. Finally, recent evidence for the kinds of memory rehabilitation procedures with proven efficacy were offered. The existent memory rehabilitation technique have focused on prompt of residual explicit memory, use of preserved implicit memory, utilization of memory external memory aids. A suggestion of memory training based on brain plasticity as a novel approach is offered.

• Cartoon and Animation Studies
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• s.38
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• pp.71-91
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• 2015

This study is a process to study the life drawing teaching method considering professional characteristics in animation and has a study objective to design the model and teaching method which applies the strategies considering the creative mechanism of the brain. Recently, study results about integrated teaching method are being announced which apply brain based learning principles as the alternative arguments about teaching methods in each area based on creativeness. In other words, integrated education based on creative mechanism in the brain is applied not only to fine arts and drawing education, but also to the entire areas of the arts. Life drawing is an area which demands comprehensive teaching method that vivid expressions could be skillfully obtained by understanding the communication methods with the objects through cognitive senses, creativeness and movements beyond the structural knowledge about human body. Therefore in this study, the strategies and methods for the skillfulness of life drawing and consequently arranged education model structure drawing are to be designed based on the creativeness, study materials and content factors which were analyzed in previous stages of this study. In order to combine the content factors based on creativeness and study materials of the brain which are the results of previous studies, the conclusion has been reached that 5 step cognitive strategy stages to wake brain senses, flexibilize the brain, purify the brain, integrate the brain and become the master of the brain. Strategic methods to execute this were designed with brain gym, right brain energization drawing and HSP(high-level cognizance) training. Teaching and learning model structure diagram which is designed based on this is to be continued to teaching and learning guidelines during the relevant semesters after the research.

• Sleep Medicine and Psychophysiology
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• v.12 no.1
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• pp.5-10
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• 2005

Study in the field of sleep and memory has greatly expanded recently and the number of publications supporting the association between sleep and memory consolidation is rapidly growing. This study presents evidence related to sleep-dependent memory consolidation, ranging from behavioral task-performing studies to molecular studies, and several arguments against the association. Basic researches show that many genes are upwardly regulated during sleep and patterns of brain activation seen during daytime task training are repeated during subsequent REM sleep. Several electrophysiological studies demonstrate the correlation between spindle density increase following training and subsequent improvement in performing the training task. Overnight improvement or deterioration in task performance correlates with REM or SWS sleep. In the end, a lot of issues remain to be studied and discussed further in the future in spite of supporting evidence now available.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.18
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• pp.7811-7816
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• 2014

Background: Despite advances in radiotherapy, overall survival of glioblastoma multiforme (GBM) patients is still poor. Moreover dosimetrical analyses with these newer treatment methods are insufficient. The current study is aimed to compare intensity modulated radiation therapy (IMRT) linear accelerator (linac) and helical tomotherapy (HT) treatment plans for patients with prognostic aggressive brain tumors. Material and Methods: A total of 20 GBM patient plans were prospectively evaluated in both linac and HT planning systems. Plans are compared with respect to homogenity index, conformity index and organs at risk (OAR) sparing effects of the treatments. Results: Both treatment plans provided good results that can be applied to GBM patients but it was concluded that if the critical organs with relatively lower dose constraints are closer to the target region, HT for radiotherapeutical application could be preferred. Conclusion: Tomotherapy plans were superior to linear accelerator plans from the aspect of OAR sparing with slightly broader low dose ranges over the healthy tissues. In case a clinic has both of these IMRT systems, employment of HT is recommended based on the observed results and future re-irradiation strategies must be considered.