• Title/Summary/Keyword: Bps

Search Result 373, Processing Time 0.031 seconds

Identification of Gene Expression Signatures in the Chicken Intestinal Intraepithelial Lymphocytes in Response to Herb Additive Supplementations

  • Won, Kyeong-Hye;Song, Ki-Duk;Park, Jong-Eun;Kim, Duk-Kyung;Na, Chong-Sam
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.29 no.10
    • /
    • pp.1515-1521
    • /
    • 2016
  • Anethole and garlic have an immune modulatory effects on avian coccidiosis, and these effects are correlated with gene expression changes in intestinal epithelial lymphocytes (IELs). In this study, we integrated gene expression datasets from two independent experiments and investigated gene expression profile changes by anethole and garlic respectively, and identified gene expression signatures, which are common targets of these herbs as they might be used for the evaluation of the effect of plant herbs on immunity toward avian coccidiosis. We identified 4,382 and 371 genes, which were differentially expressed in IELs of chickens supplemented with garlic and anethole respectively. The gene ontology (GO) term of differentially expressed genes (DEGs) from garlic treatment resulted in the biological processes (BPs) related to proteolysis, e.g., "modification-dependent protein catabolic process", "proteolysis involved in cellular protein catabolic process", "cellular protein catabolic process", "protein catabolic process", and "ubiquitin-dependent protein catabolic process". In GO analysis, one BP term, "Proteolysis", was obtained. Among DEGs, 300 genes were differentially regulated in response to both garlic and anethole, and 234 and 59 genes were either up- or down-regulated in supplementation with both herbs. Pathway analysis resulted in enrichment of the pathways related to digestion such as "Starch and sucrose metabolism" and "Insulin signaling pathway". Taken together, the results obtained in the present study could contribute to the effective development of evaluation system of plant herbs based on molecular signatures related with their immunological functions in chicken IELs.

Effects of antioxidants on viability, plasma membrane integrity and apoptosis in porcine ovarian granulosa cells damaged by bromopropane (항산화제가 Bromopropane에 의해 손상된 돼지 과립막세포의 생존율, 원형질막 온전성 및 apoptosis에 미치는 영향)

  • Lee, Seunghyung;Park, Hee-Woo;Lee, Sang-Hee;Cheong, Hee-Tae;Park, Choon-Keun;Yang, Boo-Keun
    • Journal of Embryo Transfer
    • /
    • v.31 no.3
    • /
    • pp.145-151
    • /
    • 2016
  • The purpose of this study was to examine the effects of taurine and vitamin E on ovarian granulosa cells damaged by bromopropane (BP) in pigs. We evaluated cell viability, plasma membrane integrity (PMI) and apoptotic morphological change in porcine ovarian granulosa cells. The cells were treated with 1-BP (0, 5.0, 10, and $50{\mu}M$), 2-BP (0, 5.0, 10, and 50 mM), taurine (0, 5.0, 10, and 25 mM), and vitamin E (0, 100, 200, and $400{\mu}M$) for 24 h. $10{\mu}M$ 1-BP and $50{\mu}M$ 2-BP inhibited viability and PMI, and induced apoptosis in porcine ovarian granulosa cells (p < 0.05). Cell viability and PMI were increased by taurine (10 and 25 mM) and vitamin E (100 and $200{\mu}M$), and apoptosis decreased (p < 0.05). Finally, the porcine ovarian granulosa cells were co-treated with BPs ($10{\mu}M$), taurine (10 mM) and/or vitamin E ($200{\mu}M$). Cell viability and PMI in the co-treated cells were increased, and apoptosis was decreased. In conclusion, taurine and vitamin E can improve cell viability and inhibition of apoptosis in porcine ovarian granulosa cells damaged by bromopropane.

Study on Liquid Crystal Displays Utilizing Kerr effect (액정의 Kerr 효과를 이용한 액정표시소자 연구)

  • Kim, Min-Su;Kang, Byeong-Gyun;Jung, Jun-Ho;Ha, Kyung-Su;Song, Eun-Gyoung;Yoon, Suk-In;Kim, Mi-Young;Lee, Myong-Hoon;Lee, Seung-Hee
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2009.06a
    • /
    • pp.295-296
    • /
    • 2009
  • There are various application of liquid crystal materials to devices, especially, blue phase liquid crystal (BPLC) and nano-structured liquid crystal mixture have been studied recently because BPs existing temperature range has been expanded by polymer-stabilization and liquid crystal has been confined in room which has certain coherence length so that their particular characters, such as fast response time and optically isotropic state at no electric field, could apply to advanced liquid crystal display devices. However, there is an crucial problem which is high operating voltage from low Kerr constant and limited electric field utilization using in-plain electric field. In this paper, we will analyze cell structure in the way of using electric field and show effective electric field utilization to reduce operating voltage.

  • PDF

Apoptosis Induced by Adenosine 5'-triphosphate in Mouse Leukemic Cells (Mouse Leukemia 세포에서 Adenosine 5'-triphosphate에 의한 Apoptosis)

  • Joo, Nan-Young;Park, Kyu-Sang;Chung, Hae-Sook;Kong, In-Deok;Lee, Joong-Woo
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.1 no.6
    • /
    • pp.817-824
    • /
    • 1997
  • Extracellular ATP elicits various biological responses and plays a significant role in physiological regulation. Recently, ATP-induced growth inhibitions were reported in some tumor cell lines, but these effects and mechanisms are not well hewn. This study was conducted to investigate ATP-induced growth inhibition in mouse $leukemic(P388D_1)$ cells. ATP inhibited cell growth in a dose-dependent manner as analyzed by MTS assay$(IC_{50}: 33.1\;{\mu}M)$. Nucleotides other than ATP, such as ADP$(37.5;{\mu}M)$ and AMP$(33.2;{\mu}M)$ had the same effects as ATP but adenosine$(57.8;{\mu}M)$ showed less effect than ATP. ATP attenuated the cells in $G_0/G_l\;and\;G_2/M$ phases but increased those in S phase in flow cytometric analysis. Hypodiploid cells$(A_0)$, the presumptive findings of apoptosis, were found among the ATP-treated cells. ATP induced DNA fragmentation into $180{\mu}200\;bps $as measured by electrophoresis. some apoptotic cells were stained by TUNEL method. ATP increased the intracellular free $Ca^{++}$concentration$([Ca^{++}]_i)$ and the increment of $([Ca^{++}]_i)$ was caused by influx from the extracellular space. These results suggest that extracellular ATP induces growth inhibition through apoptosis.

  • PDF

Fire Detection of a Building Using Wireless Multi-point Temperature Sensors (무선 다점 온도센서에 의한 빌딩의 화재 탐지)

  • Kim, Chi-Yeop;Kwon, Il-Bum
    • Journal of the Korean Society for Nondestructive Testing
    • /
    • v.24 no.5
    • /
    • pp.494-498
    • /
    • 2004
  • Fire accidents often happen in large buildings because large buildings are equipped with heavy electrical wiring and piping. When fire is to be occurred in those buildings, it is very dangerous to People and building structures. Therefore, multi-point wireless temperature sensors for large buildings are necessary in order to detect fire in the early time and thus to minimize the loss. A wireless device was composed of the transmitter and receiver. The specification of this device was as follows: 915MHz of transmitted frequency, 4 channels, 9600bps of the transmitted speed, and 10mW of the transmitted power. We confirmed through experiment that the temperature was well sensed and fire location was determined by the 4 channel sensors of the developed sensor system.

An Evaluation of Nuclear Design Characteristics of Duplex Burnable Absorber Rods (이중구조 가연성 독봉의 핵설계 특성 평가)

  • 이대진;김명현;송근우;정연호
    • Proceedings of the Korea Society for Energy Engineering kosee Conference
    • /
    • 2002.11a
    • /
    • pp.71-79
    • /
    • 2002
  • Nuclear design characteristics of duplex burnable poison rod were evaluated based on 24 month cycle fuel for Korean Standard Nuclear Plant. A fuel assembly with duplex burnable poison rod was designed for an equivalent assembly to 16 gadolinia BPs. Duplex BP is composed of inner region of natural U-12wt%Gd$_2$O$_3$ and outer shell of 4.95wt%UO$_2$-2wt%Er$_2$O$_3$. In order to compare this duplex option, assemblies with 140 erbia pins were designed as an alternative option. The variation of k-infinitive, rod worth, pin peaking and MTC were compared. Duplex BP had the better neutronic performance than gadolinia BP in all parameters. However, Duplex BP was worse than erbia BP in the aspect of safety.

  • PDF

QoS-Aware Approach for Maximizing Rerouting Traffic in IP Networks

  • Cui, Wenyan;Meng, Xiangru;Yang, Huanhuan;Kang, Qiaoyan;Zhao, Zhiyuan
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • v.10 no.9
    • /
    • pp.4287-4306
    • /
    • 2016
  • Network resilience provides an effective way to overcome the problem of network failure and is crucial to Internet protocol (IP) network management. As one of the main challenges in network resilience, recovering from link failure is important to maintain the constancy of packets being transmitted. However, existing failure recovery approaches do not handle the traffic engineering problem (e.g., tuning the routing-protocol parameters to optimize the rerouting traffic flow), which may cause serious congestions. Moreover, as the lack of QoS (quality of service) restrictions may lead to invalid rerouting traffic, the QoS requirements (e.g., bandwidth and delay) should also be taken into account when recovering the failed links. In this paper, we first develop a probabilistically correlated failure model that can accurately reflect the correlation between link failures, with which we can choose reliable backup paths (BPs). Then we construct a mathematical model for the failure recovery problem, which takes maximum rerouting traffic as the optimizing objective and the QoS requirements as the constraints. Moreover, we propose a heuristic algorithm for link failure recovery, which adopts the improved k shortest path algorithm to splice the single BP and supplies more protection resources for the links with higher priority. We also prove the correctness of the proposed algorithm. Moreover, the time and space complexity are also analyzed. Simulation results under NS2 show that the proposed algorithm improves the link failure recovery rate and increases the QoS satisfaction rate significantly.

A study on decision on scalable coding method for IPTV service over heterogeneous network (혼재망에서 IPTV 서비스를 위한 계층부호화 방식 결정 방법에 대한 연구)

  • Kim, Dae-Yeon;Suh, Doug-Young;Kim, Young-Soo;Kim, Jin-Sang
    • Journal of Broadcast Engineering
    • /
    • v.12 no.2
    • /
    • pp.93-101
    • /
    • 2007
  • In heterogeneous networks SVC (Scalabile Video Coding) will be used for IPTV service. This paper analyses how to determine the optimal inter-layer reference scheme according to final level to be displayed in hybrid scalable coding which consists of spatial, quality and temporal layer. It determines where to stop layering quality layer stacks in lower spatial layer according to the relationship between noise induced by loss of high frequency component eliminated by filter in order to get rid of aliasing when spatial layering is processed and noise induced by quantization when quality layering is processed. This paper shows the choice of the level of layering between spatial and quality to get better coding efficiency and then presents what is needed for determining it.

Performance Analysis of Multicarrier CDMA System with Adaptive Modulation in Wireless Environment (무선환경 하에서 적응형 변조기를 적용한 다중 반송파 CDMA 시스템의 성능 분석)

  • Lee, Kwang-Hee;Kim, Hang-Rae;Han, Tae-Young;Kim, Nam
    • Proceedings of the Korea Contents Association Conference
    • /
    • 2003.11a
    • /
    • pp.289-302
    • /
    • 2003
  • In this paper, the performance of a multicarrier CDMA system applying adaptive modulation and adaptive subchannel allocation scheme is analyzed in wireless environment. In case of the proposed system, total subchannels is 4 and data is transmitted over 2 subchannels with the biggest fading, Threshold of each channels is 5.2 ㏈, 9 ㏈, 13.2 ㏈ and 8.4 ㏈, 12.2 ㏈, 16.3 ㏈. The BER of 10-3 is 8.1 ㏈. This is increased 12.9 ㏈ in comparison with the existing system. The BPS according to average channel is needed average E$_{b}$ N$_{o}$ of about 15 ㏈ in 7 bit.t.

  • PDF

Development of CINEMA Mission Uplink Communication System

  • Yoon, Na-Young;Yoon, Se-Young;Kim, Yong-Ho;Yoon, Ji-Won;Jin, Ho;Seon, Jong-Ho;Chae, Kyu-Sung;Lee, Dong-Hun;Lin, Robert P.
    • Journal of Astronomy and Space Sciences
    • /
    • v.29 no.1
    • /
    • pp.33-40
    • /
    • 2012
  • Triplet Ionospheric Observatory (TRIO) CubeSatforIon, Neutral, Electron MAgneticfields (CINEMA) is a CubeSat with the weight 3 kg that will be operated in the orbit conditions of about 800 km altitude and $90^{\circ}$ inclination angle, using the S-band and ultra-high frequency (UHF)-band communication frequencies. Regarding the communication antenna loaded on the satellite, the two patch antennas has the downlink function in the S-band, whereas the two whip antennas has the function to receive the command sent by the ground station to the satellite in the UHF-band. The uplink ground station that communicates through the UHF-band with the CINEMA satellite was established at Kyung Hee University. The system is mainly composed of a terminal node controller, a transceiver, and a helical antenna. The gain of the helical antenna established at the Kyung Hee University ground station was 9.8 dBi. The output of the transceiver was set to be 5 W (6.9 dB) for the communication test. Through the far-field test of the established system, it was verified that the Roman characters, figures and symbols were converted into packets and transmitted to the satellite receiver in the communication speed of 9,600 bps.