• Transactions of the Korean Society of Mechanical Engineers
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• v.15 no.2
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• pp.436-444
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• 1991

A computational method has been developed to analyze the bone-remodeling induced by external fixator. The method was based on the Finite Element Method (FEM) in combination with numerical formulation of adaptive bone-remodeling theories. As a feed-back control variable, compressive strain and effective stress were used to determine the surface remodeling and internal (density) remodeling respectively. Surface remodeling and internal remodeling were combined at each time step to predict the rel situation. A noticeable shape and density change were detected at the region between two pins and density change was decreased with time increment. At final time step, the shape and density distribution were converged closely to its original intact bone model. Similar change was detected in stress distribution. The altered stress distribution due to the pin and external fixator converged to the intact stress distribution with time.

• Journal of the Korean Society for Precision Engineering
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• v.23 no.6 s.183
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• pp.180-186
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• 2006

To investigate the bone remodeling phenomenon around implant device, 3-D mathematical simulation model was developed. Strain energy density from the finite element method was chosen for the indicator for remodeling process. Recursive calculations continued until converged results between FEM and mathematical model. For a osteo-integration example, bone-remodeling process in a implanted tibia of beagle was adapted. Calculated results indicated that the bone densities around screw pitch were increased which indicates firm fixations between the bone and implant. Screw design parameters have an influence on initial stability of the implant rather than remodeling process.

• Journal of Biomedical Engineering Research
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• v.13 no.4
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• pp.353-362
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• 1992

The stress distribution of bone is altered by the rigid bone plate, sometimes resulting in unfavorable osteoporosis. The rigidity and the biocompatibility are important factors for the design of prosthesis. However, it is also necessary to consider the effect on the bone remodeling. In this paper, it is attempted to establish an approximate and simple method to predict the trend of the configuration of surface bone remodeling for the case of a bone plate using stress analysis. Thus, three dimensional finite element model of plated-human femur is generated and simulated. In addition. the stress difference method (SDM) is introduced and attempted to demonstrate the configuration of surface bone remodeling of the plated-human femur. The results are compared with those of invivo tests and the feasibility of the stress difference method is discussed.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2004.10a
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• pp.1198-1201
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• 2004

To investigate the bone remodeling phenomenon around screw tooth of the implant for osteointegration, a finite element model of the screw was developed. Strain energy density was chosen for the indicator for remodeling process. The modified mathematical equation for remodeling process was applied to 2-dimensional tibia and implant model under static bending state Caculated results show reliable remodeling process compared with histology data.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.2 s.173
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• pp.329-337
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• 2000

An investigation has been performed to develop an analysis tool based on a nonlinear beam theory, which can be used to predict the long-term behavior of an artificial hip joint. The nonlinear behav ior of the femur arise from the coupled dependence of the bone density and the mechanical properties on each other. The beam theory together with its numerical algorithm is developed to take into account the nonlinear bone remodeling process of the femur that is long enough to be assumed as a beam. A piecewise linear curve for the bone remodeling rate is used in the bone remodeling theory and the surface area density of bone is modeled as the third order polynomial function of bone density. At each section of the beam, a constant curvature is assumed and the longitudinal strains are also assumed to vary linearly across the section. The Newton-Rhapson iteration method is used to solve the nonlinear equations for each cross section of the bone and a backward method is used to march along the time. The density and the remodeling signal ar, calculated along with time for the various time steps, and the developed beam theory has been verified by comparing with the results of finite element analysis of a remodeling bone with an artificial hip joint of titanium prosthesis subjected to uni-axial loads and pure bending moment. It is concluded that the developed beam theory can be used to predict the long-term behavior of the femur and thus to design the artificial hip prosthesis.

• Journal of Korean Dental Science
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• v.9 no.2
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• pp.55-62
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• 2016

Purpose: Alveolar bone develops with tooth eruption and is absorbed following tooth extraction. Various ridge preservation techniques have sought to prevent ridge atrophy, with no superior technique evident. Collagen has a long history as a biocompatible material. Its usefulness and safety have been amply verified. The related compound, atelocollagen, is also safe and displays reduced antigenicity since telopeptides are not present. Materials and Methods: The current study evaluated whether the $Rapiderm^{(R)}$ atelocollagen plug (Dalim Tissen, Seoul, Korea) improves tissue healing of extraction sockets and assessed the sequential pattern of bone regeneration using histology and microcomputed tomography in six beagle dogs. To assess the change of extraction socket, hard tissues were examined 2, 4, 6, and 8 weeks after tooth extraction. Result: The experimental groups showed better bone fill with slow remodeling process compared to the control groups although there was no statistical difference between groups. Conclusion: The atelocollagen seems to have a tendency to slow bone remodeling in the early phase of healing period and maintain remodeling capacity until late phase of remodeling. Also, use of atelocollagen increased the bone-to-tissue ratio compared to healing of untreated extraction socket.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.7
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• pp.1103-1109
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• 2003

An adaptive bone remodeling is simulated by using the cellular automata (CA) method. It is assumed that bone tissue consist of bone marrow, osteoclast, osteoblast cell or osteoprogenitor cell. Two types of local rule are adopted; those are the metabolism rule and adaptive bone formation rule. The metabolism rule is based on the interactions of cells and the bone formation rule is based on the adaptation against the mechanical stimulus. The history of load and memory of mechanical stimulus are also considered in the local rules. As a result, the pattern of distribution of the bone tissue is dynamically adequate and it is similar to intact cancellous bone.

• Archives of Craniofacial Surgery
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• v.21 no.3
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• pp.166-170
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• 2020

Background: The standard treatment of nasal bone fractures in pediatric patients is closed reduction. Conservative treatment is sometimes performed, but poses a risk of nasal deformity. The aim of this study was to evaluate the outcomes of bone remodeling in pediatric nasal fractures. Methods: Information was extracted from the medical records of patients under 12 years of age who received conservative treatment for a nasal bone fracture and underwent follow-up computed tomography (CT) examinations. The initial fracture and its outcomes over time were graded as excellent, good, or fair according to the malalignment, displacement, or irregularity of the fractured segments. The outcomes of remodeling were evaluated through changes in the grade of the fracture between initial and subsequent CT scans. Results: The review identified 16 patients between March 2015 and December 2019. Their mean age was 6.2 years, and the average follow-up period was 4.9 months. Three of the five patients with a plane I frontal impact showed improved outcomes of remodeling from good to excellent, and the remaining two patients, improved from fair to good. Eight of the 11 patients with plane I lateral impacts showed improved outcomes, from good to excellent, while one patient, improved from fair to good, one patient, improved from fair to excellent, and one patient showed no interval changes. Conclusion: In 15 of these 16 patients with non-severe fractures, the bony contour improved through remodeling, without surgical intervention. Therefore, we suggest that conservative treatment is a feasible option for mild pediatric nasal fractures.

• Progress in Medical Physics
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• v.6 no.2
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• pp.111-125
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• 1995

The stress distribution of bone is altered by the rigid bone plate, sometimes resulting in unfavorable osteoporosis. The rigidity and the biocompatibility are important factors for the design of prosthesis, however, it is also necessary to consider the effect on the bone remodeling. In this paper, it is attempted to establish an approximate and simple method to predict the trend of the configuration of surface bone remodeling upon a bone plate using stress analysis. Thus, three dimensional finite element model of plated-human femur is generated and simulated. In addition, the stress difference method (SDM) is introduced and attempted to demonstrate the configuration of surface bone remodeling of the plated-human femur.

• Journal of Biomedical Engineering Research
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• v.26 no.6
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• pp.365-372
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• 2005

Topology optimization method has a great advantage and capability over a conventional shape optimization technique because it optimizes a topology as well as a shape and size of structure. The purpose of the present study, using topology optimization method with an objective function of minimum compliance as a mechanism of bone remodeling, is to examine which shape factors of femur is strongly related with the curvature of femoral shaft. As is expected, the optimized curvature increased definitely with neck angle among the shape factors and showed a similar trend with the measured curvature to neck angle. Therefore, the topology optimization method can be successfully applied in the analysis of bone remodeling phenomenon in the subsequent studies.