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http://dx.doi.org/10.3795/KSME-A.2003.27.7.1103

A Study of Adaptive Bone Remodeling by Cellular Automata Method  

Moon, Byung-Young (부산대학교 항공우주공학과)
Park, Jung-Hong (부산대학교 대학원 기계설계공학과)
Son, Kwon (부산대학교 기계공학부)
Publication Information
Transactions of the Korean Society of Mechanical Engineers A / v.27, no.7, 2003 , pp. 1103-1109 More about this Journal
Abstract
An adaptive bone remodeling is simulated by using the cellular automata (CA) method. It is assumed that bone tissue consist of bone marrow, osteoclast, osteoblast cell or osteoprogenitor cell. Two types of local rule are adopted; those are the metabolism rule and adaptive bone formation rule. The metabolism rule is based on the interactions of cells and the bone formation rule is based on the adaptation against the mechanical stimulus. The history of load and memory of mechanical stimulus are also considered in the local rules. As a result, the pattern of distribution of the bone tissue is dynamically adequate and it is similar to intact cancellous bone.
Keywords
Cellular Automata; Bone Remodeling;
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1 Wolff J., 1869, 'Ueber die Bedeutung der Architectur der Spongiosen fur die Frage vom Knochenwachsthum,' Zentralblatt fur die Medizinischen Wissenschaften, pp. 223-234
2 Carter, D. R., Orr, T. E. and Fyhrie, D. P., 1989, 'Relationships between Loading History and Femoral Cancellous Bone Architecture,' Journal of Biomechanics, Vol. 22, No. 3, pp. 231-244   DOI   ScienceOn
3 Orr, T. E., Beaupre, G. S., Carter, D. R. and Schurman, D. J., 1990, 'Computer Predictions of Bone Remodeling around Porus-Coated Implants,' Journal of Arthroplasty, Vol. 5, No. 3, pp. 191-200   DOI   ScienceOn
4 Huiskes, R., Weinans, H., Grootenboer, H. J., Dalstra, M., Fudala, B. and Slooff, T. F., 1987, 'Adaptive Bone-Remodeling Theory Applied to Prosthetic-Design Analysis,' Journal of Biomechenics., Vol. 20, No. 11/12, pp. 1135-1150   DOI   ScienceOn
5 Carter, D. R., 1987, 'Mechanical Loading History and Skeletal Biology,' Journal of Biomechanics, Vol. 20 No. 11/12 ,pp.1095-1109   DOI   ScienceOn
6 Beaupre, G. S., Orr, T. E. and Carter, D. R., 1990, 'An Approach for Time-Dependent Bone Modeling and Remodeling: A Preliminary Remodeling Simulation,' Journal of Orthopaedic Research, Vol. 8, pp. 662-670   DOI
7 Huiskes, R., Weibans, H. and Van Rietbergen, B., 1992, 'The Relationship between Stress Shielding and Bone Resorption around Total Hip Stems and the Effects of Flexible Materials,' Clinical Orthopaedics and related Research, Vol. 274, pp. 124-134
8 Weinans, H., Huiskes, R. and Grootenboer, H. J., 1992, 'Effects of Material Properties of Femoral Hip Components on Bone Remodeling,' Journal of Orthopaedic Research, Vol. 10, pp. 845-853   DOI
9 Weinans,H., Huiskes,R. and Grootenboer,H.J., 1994, 'Effects of Fit and Bonding Characteristics of Femoral Stems on Adaptive Bone Remodeling,' Trans.ASME, Journal of Biomechanical Engineering., Vol. 116, pp. 393-400   DOI   ScienceOn
10 Beaupre, G. S., Orr, T. E. and Carter, D. R., 1990, 'An Approach for Time-Dependent Bone Modeling and Remodeling: Theoretical Development,' Journal of Orthopaedic Research, Vol. 8, pp. 651-661   DOI
11 Carter, D. R., Fyhrie, D. P. and Whalen, R. T., 1987, 'Trabecular Bone Density and Loading History: Regulation of Connective Tissue Biology by Mechanical Energy,' Journal of Biomechanics, Vol. 20 No. 8, pp. 785-794   DOI   ScienceOn
12 Weinans, H., Huiskes, R. and Grootenboer, H. J., 1992, 'The Behavior of Adaptive Bone-Remodeling Simulation Models,' Journal of Biomechanics, Vol. 25, No. 12, pp. 1425-1441   DOI   ScienceOn
13 Fyhrie, D. P. and Carter, D. R., 1990, 'Femoral Head Apparent Density Distribution Predicted from Bone Stresses,' Journal of Biomechanics, Vol. 23, No. 1, pp. 1-10   DOI   ScienceOn