• Bulletin of the Korean Chemical Society
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• v.34 no.1
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• pp.121-127
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• 2013

New types of monocyclic ${\beta}$-lactams constitute an important class of compounds due to their unique structures and natures. Here, the design and synthesis of new 4-alkylthio monocyclic ${\beta}$-lactams 2a and 3a are reported. Significantly, compounds 2a and 3a, while keeping a monocyclic system, were designed to contain all of the substructures provided by the cleavage of C(2)-C(3) bond in penicillins. Efficient synthetic pathways for compounds 2a and 3a were established based on two different strategies. Compound 2a was synthesized from raw materials, using 4-acetoxyazetidin-2-one as a key intermediate, through a ten-step synthetic sequence in 3% overall yield. Compound 3a was synthesized from potassium salt of penicillin G (17), using the degraded product 20 as a key intermediate, through a six-step synthetic sequence in 11% overall yield. 4-Alkylthioazetidin-2-one derivatives, introduced in this study, could serve as valuable intermediates for the development of new monocyclic ${\beta}$-lactams.

• The Korean Journal of Zoology
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• v.6 no.2
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• pp.16-20
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• 1963

Gamma 선을 조사한 triglycine용액을 spectrophotometric trechnique와 ultraviolet absorption을 써서 연구하여 다음 결과를 얻었다. 1. 조사된 striglycine-biuret complex 의 dose-yield curve는 방사선의 간접작용을 보여주는 전형적인 예를 보여주었다. 2. G(CO-NH)는 s1.75였다. 3. Dose-yield data에서 보면 peptide bond reputure는 선량을 증가함에 따라서 감소하는 증가율을 나타내어 분해산물들이 free radical 과 compete함을 알 수있었다. 4. 증가된 triglycine의 molecular extinction coefficient는 5 $\times$1020 ev./ml가지는 비례적증가를 나타내었고 이보다 높은 선량에서는 1.9$\times$1021 ev/ml 에 이르기까지 직선적 감소를 보여 carbonyl compound 의 G치는 0.80이였다.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.33 no.2
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• pp.58-67
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• 2001

MOW (Mixed Office Waste) mainly consisted of photocopied paper is being recycled to produce tissue or fine paper products. Toner particles that are fused and set on paper surface in photocopying process turns into large and plate-shaped particles after repulping which prevents them to be removed effectively in flotation deinking. The immediate purpose of this study is to find the effective deinking technology that increases the recycling potential of photocopied papers for manufacturing tissue and fine paper products. In this study the effects of pulping temperature and the type of hydrophobic groups of nonionic surfactants on the deinking efficiency of photocopied paper has been investigated. Particle size distribution of the toner particles after pulping and flotation, brightness, yield and ash removal were investigated. The size of toner particles after pulping increased as the pulping temperature was increased. When pulping at the low temperature finer toner particles were generated, however, greater amount of toner particles was found to attach to the fiber. When the pulping temperature was greater than Tg of the toner, the amount of coarse hairy particles increased. When nonionic surfactants with a double bond in hydrophobic groups were used, toner removal efficiency, brightness and ash removal were increased. As the addition level of surfactant was increased, yield decreased rather sharply without improving brightness.

• Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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• 2006.06a
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• pp.129-136
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• 2006

Although cleaner and cheaper deinking of ONP could be performed at the neutral or low alkaline condition excessive loss from froth-flotation is unavoidable and so reduction of alkali or caustic soda dosage sacrifices recycling yield. Now the new trade-off regarding alkali dosage versus flotation yield is urgently required in order to set the optimized neutral or low alkaline deinking process of ONP. Lipase from Thermomyces Lanuginosus has an effect on desizing and deacetylation reaction and it could be applied to the stock of pre flotation secondary stage in order to reduce the flotation reject without the sacrifice of optical properties of flotation accepts. Instead of inorganic base, lipase could be applied as a biochemical catalyst for the selective modification of valuable hydrophobic particles in deinking stock, for example cellulose fines and inorganic fillers covered by hydrophobic additives or contaminants. When the enzymatic hydrolysis of ester bond could be made on the surface of hydrophobic particulates, unwanted float of fine particles could be prevented. Now the enhancement of flotation selectivity or the modification of the hydrophobicity of deinking stock is expected to be promoted by the enzymatic pre treatment. And the reduction of recycling cost with the saves of raw material, recovered paper would be possible as a result.

• Archives of Pharmacal Research
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• v.22 no.5
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• pp.459-463
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• 1999

The effects of the hindered and non-hindered water soluble long-chain disulfide bonds on the stability and cytotoxicity of the ricin A chain (RTA) immunotoxin were examined. The RTA immunotoxins were prepared with the Fab fragments of anti-common acute lymphoblastic leukemia antigen (CALLA) monoclonal antibody (Fab-RTA) using sulfosuccinimidyl-6-[(-methyl-(-2-pyridyldithio)toluamido]toluamido]hexanoate (S-LC-SMPT) and sulfosuccinimidyl-6-[3-(2-pyridyldithio-propionamido]hexanoate (S-LC-SPDP). The prepared Fab-RTA immunotoxins were evaluated for their conjugation yield, immunoreactivity, thermal and disulfide bond stability and cytotoxicity. The conjugation yield of the Fab-RTA immunotoxin from the water soluble long chain crosslinking agents, S-LC-SMPT and S-LC-SPDP, were comparable. Both Fab-RTA immunotoxins exhibited a similar immunoreactivity and thermal stability in aqueous solution. However, S-LC-SMPT -mediated Fab-RTA, sterically hindered, showed an enhanced disulfide bond stability in vitro over S-LC-SPDP mediated one. In the cytotoxicity against antigenic cell Daudi, the S-LC-SMPT -mediated RTA immunotoxin maintained a comparable cytotoxicity, compared with S-LC-SPDP mediated Fab-RTA immunotoxin.

• Asia-Pacific Journal of Business
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• v.11 no.4
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• pp.255-269
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• 2020

Purpose - This paper analyzes the market efficiency focusing on the long memory properties of the domestic futures market. By decomposing futures prices into yield and volatility and looking at the long memory properties of the time series, this study aims to understand the futures market pricing and change behavior and risks, specifically and in detail. Design/methodology/approach - This study analyzes KOSPI 200 futures, KOSDAQ 150 futures, 3 and 10-year government bond futures, US dollar futures, yen futures, and euro futures, which are among the most actively traded on the Korea Exchange. To analyze the long memory and market efficiency, we used the Variance Ratio, Rescaled-Range(R/S), Geweke and Porter-Hudak(GPH) tests as semi- parametric methods, and ARFIMA-FIGARCH model as the parametric method. Findings - It was found that all seven futures supported the efficiency market hypothesis because the property of long memory turned out not to exist in their yield curves. On the other hand, in futures volatility, all 7 futures showed long memory properties in the analysis, which means that if new information is generated in the domestic futures market and the market volatility once expanded due to the impact, it does not decrease or shrink for a long period of time, but continues to affect the volatility. Research implications or Originality - The results of this paper suggest that it can be useful information for predicting changes and risks of volatility in the domestic futures market. In particular, it was found that the long memory properties would be further strengthened in the currency futures and bond rate futures markets after the global financial crisis if the regime changes of the domestic financial market are taken into account in the analysis.

• Journal of Korean Society of Steel Construction
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• v.24 no.5
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• pp.535-547
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• 2012

PSRC column is a concrete encased steel angle column. In the PSRC column, the steel angles placed at the corner of the cross-section resists bending moment and compression load. The lateral re-bars welded to steel angles resist the column shear and the bond between the steel angle and concrete. In the present study, current design procedures in KBC 2009 were applied to the flexure-compression, shear, and bond design of the PSRC composite column. To verify the validity of the design method and failure mode, simply supported 2/3 scaled PSRC and correlated SRC beams were tested under two point loading. The test parameters were the steel angle ratio and lateral bar spacing. The test results showed that the bending, shear, and bond strengths predicted by KBC 2009 correlated well with the test results. The flexural strength of the PSRC specimens was much greater than that of the SRC specimen with the same steel ratio because the steel angles were placed at the corner of the column section. However, when the bond resistance between the steel angle and concrete was not sufficient, brittle failures such as bond failure of the angle, spalling of cover concrete, and the tensile fracture of lateral re-bar occurred before the development of the yield strength of PSRC composite section. Further, if the weldability and toughness of the steel angle were insufficient, the specimen was failed by the fracture of the steel angle at the weld joint between the angle and lateral bars.

• Journal of the Korea Concrete Institute
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• v.25 no.2
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• pp.217-224
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• 2013

Design provisions for the development length of headed bars in ACI 318-08 include concrete compressive strength and yield strength of headed bars as design parameters but do not consider the effects of transvers reinforcement. In addition, they have very strict limitation for clear spacing and material strengths because these provisions were developed based on limited tests. In this study, splice tests using SD600 headed bars with $2d_b$ clear spacing and transverse reinforcement were conducted. Test results show that unconfined specimens failed due to prying action and bottom cover concrete prematurely spalled. The contribution of head bearing on the anchorage strength is only 15% on average implying that unconfined specimens failed before the head bearing was not sufficiently developed. Confined specimens with stirrups placed along whole splice length have enhanced strengths in bearing as well as bond because the stirrups prevented prying action and improved bond capacity. Bond failure occurred in locally confined specimens where stirrups were placed only at the ends of splice length. The stirrups at ends of splice lengths can prevent prying action but the bond capacity did not increase. From regression analysis of test results, an equation to predict anchorage strength of headed bars was developed. The proposed equation consists of bond and bearing contributions and includes transverse reinforcement index. The average ratio of tests to predictions is 1.0 with coefficient of variation of 6%.

• Transactions of the Korean hydrogen and new energy society
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• v.23 no.3
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• pp.199-206
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• 2012

HC-SCR was conducted over Co-Pt/ZSM5 catalyst coated over 200 cpsi cordierite in the condition of atomspheric pressure and $200^{\circ}C-500^{\circ}C$. Weight ratio of Co/Pt determined from EDX analysis was 8/2, which was almost equal to the weight ratio at preparation step. XPS showed that nitrates within cobalt precursor and chlorine withn Pt precursor were removed. TEM result demonstrated that crystallite size of cobalt and Pt was under 5nm. Among these tested hydrocarbon reductants, isobutane ($i-C_4H_{10}$) showed the highest de-$NO_x$ yield of 80% under the condition of the mole ratio of reductant/NOx=1.0 at $180^{\circ}C$. De-$NO_x$ yield from HC-SCR was increased as the carbon number of hydrocarbon reductant was increased. The decrease of bonding energy between C and H of HC reductant played a role to increase of de-$NO_x$ yield, which indicated that the dissociation step of C-H bond of hydrocarbon molecule might be the rate determining step of HC-SCR. The increase of oxygen concentration in the feed resulted in the decrease of de-$NO_x$ yield but the increase of CO and $N_2O$ yield.

• Computational Structural Engineering
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• v.5 no.4
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• pp.133-142
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• 1992

An analytical model was developed for predicting the pullout behavior of straight beam longitudinal bars anchored at exterior beam-column connections. The model incorporates a local bond constitutive simulation capable of considering the effects of anchored bar diameter, yield strength and the spacing, concrete compressive strength, and column pressure on the bond characteristics of deformed bars in confined conditions of exterior joints. The analytical techniques adopted in this study were shown to satisfactorily predict the results of pullout tests on straight bars embedded in confined concrete specimens. An evaluation of the ACI-ASCE Committee 352 development length requirements in exterior joint conditions was made using the developed analytical approach. The results of this analytical evaluation are indicative of the conservatism of the current development length requirements in the confined conditions of exterior joints.