• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.4
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• pp.1-16
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• 2008

Purpose: The purpose of this study is to investigate the effect of Boheo-tang (B) and Boheo-tang plus cervi pantotrichum cornu (B+CP) on lactation in postpartum C57BL/6N mice. Methods: Normal saline(control), Band B+CP (8mu l/g$) were administerd p.o. twice a day for 20 days. Lactating mammary gland tissues were examined through light microscope by the way of HE staining and immunohistochemical assay. Milk producing associated gene expression were accessed by RT-PCR. Results: In mammary gland, amount of adipose tissues were decreased in both Band B+CP treated group. And the ductal branches and alveolar tissues increased in both treated group. Immunoreactivity of prolactin receptors was increased both treated group, and immunoreactivity of oxytocin receptors was increased in the B+CP treated group. In both treated group, IGF-l mRNA expression was increased and TGF-$\beta$ mRNA expression was decreased. And PRL mRNA expression was increased in the B+CP treated group. PL-l mRNA expression was decreased in the B treated group but increased in the B+CP treated group. Conclusion: This study shows that treatment of Boheo-tang and Boheo-tang plus cervi pantotrichum cornu can improve postpartum lactation in C57BL/6N mice.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.3
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• pp.25-35
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• 2009

Purpose: The purpose of this study is to investigate the effect of Boheo-tang (B) and Boheo-tang plus cervi pantotrichum cornu (B+CP) on immune response in postpartum C57BL/6N mice. Methods: Normal saline(control), B and B+CP (8${\mu}{\ell}$/g) were administerd p.o. twice a day for 20 days. Subpopulation of T and B lymphocyte were accessed by flow cytometric analysis. Results: Splenic T and B lymphocytes were increased by the treatment of B. Subpopulation of cytotoxic T lymphocytes in the spleen, were significantly increased by both treatment of B and B+CP. Subpopulation of cytotoxic T lymphcytes in the thymus, were significantly increased by both treatment of B and B+CP. IL-4 production was significantly increased by the treatment of B+CP. Conclusion: This study shows that treatment of Boheo-tang and Boheo-tang plus cervi pantotrichum cornu can improve postpartum immune response in C57BL/6N mice.

• The Journal of Korean Obstetrics and Gynecology
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• v.36 no.2
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• pp.101-113
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• 2023

Objectives: The purpose of this case study is to report clinical effectiveness of the Boheo-tang-gagambang with acupuncture, moxa and physiotherapy treatments on the after-effects of myomectomy or hysterectomy. Methods: The subjects of this study were five women who were diagnosed with uterine myoma and underwent myomectomy or hysterectomy. They mainly complained of lower abdominal pain, back pain, and pelvic pain. They received combination treatment of Korean medicine and physiotherapy. The Korean medicine included Boheo-tang-gagambang, acupuncture and moxa. The effects were evaluated through Numeric Rating Scale (NRS). Results: In this study, patient's clinical symptoms, including lower abdominal pain, low back pain, and pelvic pain, improved after hospitalization treatment. Conclusions: This case report shows that the combination treatment of Korean medicine with Boheo-tang-gagambang, acupuncture and moxa may be effective for treating after-effects of myomectomy or hysterectomy.

• Herbal Formula Science
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• v.13 no.1
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• pp.223-233
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• 2005

As woman receive many stress during pregnancy and delivery, they happen to contract to psychopathy like a postpartum depression. Postpartum depression is a serious problem if they are not treated early enough the unhappy seriousness can be resulted. A 32-yeared-old female patient with postpartum depression was taken to Dongshin University oriental medical hospital on April, 28, 2003. We diagnosed this patient as postpartum depression, which originated from and efficiency of vital energy and blood. We treated this postpartum depression patient with herb medicine(Cami-Boheo-tang),acupuncture, moxibustion, and psychical therapy. After the oriental medical treatments, the patient was improved in all complains of the postpartum disease. After this, further study and approach will be needed about the disease of the postpartum depression.

• The Journal of Korean Obstetrics and Gynecology
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• v.28 no.3
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• pp.119-127
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• 2015

Objectives The purpose of this study is to report the effect of Boheo-tang Gagambang (BG) with acupuncture and moxa treatments on the after-effects of hysterectomy. Methods Three women who were undertaken a hysterectomy within a month were enrolled in this study. They complained of abdominal pain, low back pain, nausea, fatigue, etc. BG was prescribed 3 times a day and the acupuncture and moxa treatments were applied to decrease pain and improve the symptoms. Results After the acupuncture and moxa treatments with BG, symptoms were markedly decreased. Conclusions These clinical cases indicated that BG were effective in the treatments for patients who were undertaken a hysterectomy.

• The Journal of Internal Korean Medicine
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• v.38 no.6
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• pp.1000-1006
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• 2017

Objectives: Head symptoms, such as headache and dizziness, are commonly presented in clinical practice. Although Donguibogam, the representative book of Korean medicine, contains many prescriptions for head symptoms, they are difficult to learn and apply because of the vast numbers. The aim of this study was to simplify and visualize the vast contents of Donguibogam by network analysis. Methods: 127 prescriptions for head symptoms, found in Donguibogam, were entered into a Microsoft office Excel 2013 file. This was used as a database for network analysis using the NetMiner 4 program. Results: Through network analysis, six networks for prescriptions for head symptoms in Donguibogam were established. The first network is similar to the herb composition of Cheongsangsahwa-tang (prescriptions for hwa-yeol syndrome). The second network is similar to the herb composition of Yanghyulgupung-tang (prescriptions for hyul-heo syndrome). The third network is similar to the herb composition of Sangcheongbaekbuja-hwan (prescriptions for dam-eum syndrome). The fourth network is similar to the herb composition of Heukseok-dan (prescriptions for yang-heo syndrome). The fifth network is similar to the herb composition of Boheo-eum (prescriptions for chil-jeong syndrome). The sixth network is similar to the herb composition of Bangpungtongseong-san (prescriptions for hwa-yeol syndrome). Conclusions: The results of the network analysis of 127 prescriptions for head symptoms in Donguibogam suggest that there are five major causes of head symptoms (hwa-yeol, hyul-heo, dam-eum, yang-heo, and chil-jeong), and that it is possible to prescribe Cheongsangsahwa-tang, Bangpungtongseong-san, Yanghyulgupung-tang, Sangcheongbaekbuja-hwan, Heukseok-dan, or Boheo-eum depending on the major causes.

• The Journal of Korean Medicine
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• v.41 no.3
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• pp.191-204
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• 2020

Objectives: The purpose of this study is to report the effect of Korean medicine treatment on chronic pelvic pain with gynecological diseases. Methods: Three female patients with gynecological diseases who suffered from chronic pelvic pain got Korean medicine treatment such as Boheo-tang-gagambang, acupuncture, Jungsongouhyul pharmacopuncture, moxibustion, fumigation therapy with Hyeonhosaek-tang and Sasangja-tang and physiotherapy during hospitalization. Numerical Rating Scale(NRS) of pains and percentage of other symptoms were measured every morning. Results: In three cases, after 9, 15, and 22 days of treatment in each case, pelvic pain decreased by more than 50% and other symptoms were also improved. Conclusions: These cases showed that Korean medicine treatment of chronic pelvic pain with gynecological diseases was effective for alleviating symptoms.

• The Journal of Korean Obstetrics and Gynecology
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• v.32 no.3
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• pp.142-161
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• 2019

Objectives: The purpose of this study is to report the effect and safety of traditional Korean medicine (TKM) for enhanced recovery after surgery (ERAS) after gynecological surgery. Methods: The study is conducted by analyzing the medical records of the hospitalized patients in TKM hospital. Eighty-six patients were enrolled who received TKM for ERAS after gynecological surgery from January 2015 to April 2018. We performed statistical analysis by using SPSS ver. 25.0. To prove the effect and safety of TKM for ERAS, we analyzed symptoms and Hemoglobin (Hb), aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) and serum creatinine (Cr) with glomerular filtration rate (GFR). In addition, we checked other adverse reactions that the patients complained to prove the safety of TKM for ERAS. Results: Among symptoms of pain, there was a statistically significant decrease in abdominal pain, lower back pain, and shoulder pain. Other symptoms showed statistically significant improvement in fatigue, abdominal tympanosis, operation-site discomfort, dizziness, urinary discomfort, throat discomfort, constipation, dyspepsia and colporrhagia. Anemia in both ferritin combination treatment group and herbal medicine only group showed significant improvement. There was no liver damage or renal damage by TKM. Conclusions: The result has shown that TKM for ERAS after gynecological surgery is effective and safe. The further study of TKM for ERAS with more patients is needed.

• The Journal of Korean Obstetrics and Gynecology
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• v.34 no.3
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• pp.49-64
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• 2021

Objectives: This study analyzed medical records and online survey of mothers who received herbal medicine treatment using the Jeollabuk-do Postpartum Health Support Project. Through this, we would like to discuss the proposal of a postpartum questionnaire of korean medicine for the initial examination, and the project direction. Methods: This study investigated the medical records of 46 mothers who received herbal medicine treatment using the Jeollabuk-do Postpartum Health Support Program at one korean medical hospital. The mother's general characteristics, past history, symptoms, and herbal medicine prescription were analyzed. In addition, through the 33 mothers who responded to the online survey questionnaire, 13 items including medication satisfaction, lactation, and side effects were investigated. Results: The average age of the subjects was 34.46±4.27 years. Musculo-skeletal pain was the most common in both medical records and online surveys. The date of visit from the date of delivery was 47.56±57.15 days. Boheo-tang was prescribed the most, and 84.8% of mothers answered positively about their health after taking herbal medicine. Conclusions: The satisfaction of mothers who received herbal medicine treatment through this project was very high. There were no significant side effects on the mother and the breastfeeding baby who took herbal medicine. In the future, support projects for postpartum korean medical treatment at the national or local level will be necessary.

• The Journal of Korean Obstetrics and Gynecology
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• v.37 no.1
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• pp.89-103
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• 2024

Objectives: This study analyzed an online survey targeting women and Korean medicine doctors who participated in the Yeosu City Postpartum Health Center Support Project. Through this, we would like to discuss the direction of support for postpartum health care support projects and new policies to encourage childbirth. Methods: In this study, we examined the results of an online survey from 73 women and 29 Korean medicine doctors. We examined 39 items, including basic information, childbirth-related items, Korean medicine treatment-related items, business satisfaction, and policies, answered by 73 women and 29 Korean medicine doctors who responded to the online survey. Results: The average age of women was 33.62±4.19 years, and the average age of Korean medicine doctors was 49.82±8.60 years. Musculoskeletal pain appeared most commonly in both maternal and Korean medicine doctors' online surveys. The visit date from the date of delivery was 36.87±27.06 days. Gungguijohyeol-um and Boheo-tang were widely used. The survey score of women whose main symptoms improved after taking herbal medicine was 3.04±1.15 points, and the survey score of Korean medical doctors was 4.13±0.74 points. The positive response to the policy was 73.7% for satisfaction with the overall policy to encourage childbirth, 54.8% for perceived support, and 65.7% for reduction of economic burden. Conclusions: Women who participated in the postpartum health care support project and received Korean medicine treatment and Korean medicine doctors who performed Korean medicine treatment were very satisfied. The most frequent postpartum symptom was musculoskeletal pain. The degree of improvement in main symptoms after taking herbal medicine was higher among Korean medicine doctors than among women. Among childbirth policies, the areas that should be prioritized are childbirth support projects and postpartum care projects.