• Asian-Australasian Journal of Animal Sciences
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• 제29권1호
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• pp.43-50
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• 2016

Quantitative trait locus (QTL) is a particular region of the genome containing one or more genes associated with economically important quantitative traits. This study was conducted to identify QTL regions for body weight and growth traits in purebred Korean native chicken (KNC). F1 samples (n = 595) were genotyped using 127 microsatellite markers and 8 single nucleotide polymorphisms that covered 2,616.1 centi Morgan (cM) of map length for 26 autosomal linkage groups. Body weight traits were measured every 2 weeks from hatch to 20 weeks of age. Weight of half carcass was also collected together with growth rate. A multipoint variance component linkage approach was used to identify QTLs for the body weight traits. Two significant QTLs for growth were identified on chicken chromosome 3 (GGA3) for growth 16 to18 weeks (logarithm of the odds [LOD] = 3.24, Nominal p value = 0.0001) and GGA4 for growth 6 to 8 weeks (LOD = 2.88, Nominal p value = 0.0003). Additionally, one significant QTL and three suggestive QTLs were detected for body weight traits in KNC; significant QTL for body weight at 4 weeks (LOD = 2.52, nominal p value = 0.0007) and suggestive QTL for 8 weeks (LOD = 1.96, Nominal p value = 0.0027) were detected on GGA4; QTLs were also detected for two different body weight traits: body weight at 16 weeks on GGA3 and body weight at 18 weeks on GGA19. Additionally, two suggestive QTLs for carcass weight were detected at 0 and 70 cM on GGA19. In conclusion, the current study identified several significant and suggestive QTLs that affect growth related traits in a unique resource pedigree in purebred KNC. This information will contribute to improving the body weight traits in native chicken breeds, especially for the Asian native chicken breeds.

• 한국가금학회지
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• 제50권1호
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• pp.15-22
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• 2023

본 연구는 토종 종계의 육성기 체중과 산란 능력 간의 연관성을 규명하고자 성숙 이전 주령별 체중과 이들의 초산일령, 산란율 및 난중과의 상관 관계를 분석하였다. 공시계는 (주)한협원종이 보유한 신품종 토종 종계 1,384수로써 발생부터 20주령까지의 체중과 초산일령, 초산이후 50주령까지의 일계 산란율 및 산란지수, 32주령 및 50주령 난중을 분석 대상으로 하였다. 분석 결과, 육성 초기 체중과 초산일령 간에는 정(positive)의 상관이, 육성 후기 체중과 초산일령 간에는 부(negative)의 상관이 나타났다. 육성기 체중과 일계 산란율 및 산란지수 간에는 비슷한 상관계수를 보이고, 육성전기 체중과 산란율 간에는 부의 상관이, 육성 후기 체중과는 정의 상관을 보였다. 육성기 체중과 32주령 난중 간에는 거의 상관 관계가 없는 것으로 나타났고, 50주령 난중과는 낮은 정의 상관을 보였다. 결론적으로 토종 종계에 있어서 8주령 이전까지의 육성 초기 체중과 산란 능력 간에는 거의 연관성이 없는 것으로 보여지고, 12주령 이후 육성 후기 체중과 산란 능력 간에는 정의 상관이 있는 것으로 나타났다. 이는 육성 후기 때 병아리의 체중이 증가할수록 성 성숙이 빠르고, 산란율도 높고 난중도 증가함을 시사한다. 따라서 토종 종계 모계의 경우 육성 후기 병아리의 체중 관리가 매우 중요하고, 이때 종계들의 체중이 표준 체중 이상이 되도록 유지하여야 한다.

• Nutrition Research and Practice
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• 제6권5호
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• pp.458-465
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• 2012

This study aims to determine the association between obesity-related behaviors (dietary practices, physical activity and body image) and body weight status among adolescents. A total of 382 adolescents (187 males and 195 females) aged 13 to 15 years in Kajang, Selangor participated in this study. Majority of the respondents were Malays (56.0%), followed by Chinese (30.1%) and Indians (13.9%). Dietary practices, physical activity and body image of the adolescents were assessed through the eating behaviors questionnaire, two-day dietary record, two-day physical activity record and multi-dimensional body image scale (MBIS), respectively. Body weight and height were measured by trained researchers. The prevalence of overweight and obesity (19.5%) was about twice the prevalence of underweight (10.5%). About two-thirds of the respondents (72.3%) skipped at least one meal and half of them (56.2%) snacked between meals with a mean energy intake of $1,641{\pm}452$ kcal/day. More than half of the respondents (56.8%) were practicing sedentary lifestyle with a mean energy expenditure of $1,631{\pm}573$ kcal per day. Energy intake (r = 0.153, P < 0.05), physical activity (r = 0.463, P < 0.01) and body image (r = 0.424, P < 0.01) were correlated with BMI. However, meal skipping, snacking and energy expenditure per kg body weight were not associated with body weight status. Multiple linear regression analysis showed that body image, physical activity and energy intake contributed significantly in explaining body weight status of the adolescents. In short, overweight and obesity were likely to be associated not only with energy intake and physical activity, but also body image. Hence, promoting healthy eating, active lifestyle and positive body image should be incorporated in future obesity prevention programmes in adolescents.

• 한방재활의학과학회지
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• 제15권1호
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• pp.109-126
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• 2005

Objectives : This study is to examine the influence of exorcise program to body shape and body composition of women. Exercise program is composed muscular resistance exercise and aerobic exorcise with 70min/time, 5day/week for 4weeks and designed for the reinforcement of muscular strength and the decease the decrease of obesity. Methods : The subjects of this study are 26 females who are from twenty until thirty-nine years old and are divided into two groups according to Obese Rate. normal weight group is 18 females under a BMI of 23 and overweight group is 8 females over a BMI of 23. we measured body compositon and body shape with body composition analyzer(inbody 3.0) measured body compositions are body weight, Lean body mass, base metabolic rate, body fat, %body fat, waist hip ratio, body mass index. measured 6body shade are upper arm circumference, chest circumference, waist circumference, hip circumference, thigh circumference. the measurements had been taken before exercise of each group, after 4 weeks, after 8 weeks, after 12 weeks. Body compositon and body shape of the measured data were analyzed by two-way repeated ANOVA followed by Dunnett's Post hoc test using SPSS. Differences were considered significant at p<0.05. Results and Conclusions : The weight was reduced at a significant level in overweight group after 4 weeks. Body fat percent was reduced at a significant level in normal group alter 4 weeks and overweight group after 8 weeks. Waist-hip ratio was reduced at a significant level in normal and overweight group after 4 weeks. Lean body mass and body metabolic rate were reduced but did not satisfy statistical significance. Circumference of all body parts showed an decrease after 12 weeks exercise program. Upper Arm, Chest, Waist, Hip Circumference were reduced at a significant level in overweight group after 4 weeks, but In normal group only Waist Circumference was reduced at a significant level after 4 weeks. Aerobic and Circuit weight training for 12 weeks reduced body weight and body fat percent, waist circumstance statistically significant without loss of lean body mass and body metabolic rate. Also these change was more effective in overweight group than in normal group.

• Journal of Nutrition and Health
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• 제36권9호
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• pp.924-932
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• 2003

In middle-aged men, abdominal obesity has been an important risk factor of coronary artery disease (CAD) as well as a predictor of hypertension, dyslipidemia, insulin resistance and glucose intolerance. Particularly, risks from abdominal obesity increase when adipose tissue accumulates in visceral compartment. Many studies showed that weight reduction by caloric restriction improves abdominal obesity and reduces lots of cardiovascular risk factors. Testosterone treatment also results in a significant decrease in visceral fat area and normalizes endocrine metabolism. However there is no study that compare the effect of caloric restriction with that of testosterone treatment. The purpose of this study is to investigate the effect of caloric restriction and that of testosterone treatment on body fat distribution, serum lipids and glucose metabolism in male patients with CAD. Forty five middle-aged overweight-obese men with CAD participated in 12 weeks' program. They were matched with age, body weight, body mass index (BMI) and divided into three groups : control group (n = 15) , caloric restriction group (-300 kcal/day, n = 15) and testosterone treatment group (testosterone undecanoate tablets, n = 15) . After 12 weeks, control group did not have any changes in anthropometries, lipid profile, body fat distribution, glucose metabolism and hormonal status. Expectedly, caloric restriction group showed decreases in body weight, BMI, waist to hip ratio, ％ body fat. Ten percentage of total cholesterol and 23% of triglyceride in serum were also decreased. In body fat distribution, total fat areas at both L1 and L4 levels were significantly reduced in this group without reduction in muscle of thigh and calf. However, testosterone treatment group did not have any significant changes in body weight, ％ body fat, serum lipid profile and abdominal fat distribution. In conclusion, weight reduction by caloric restriction is more beneficial in body fat distribution and serum lipid level than testosterone treatment in overweight male patients with CAD. This result suggests that modest weight reduction is possible to help decrease risk factors of CAD.

• 약학회지
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• 제50권3호
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• pp.160-165
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• 2006

Germanium is found in a range of minerals and ores and is present in foods including beans, tomato juice, oysters, tuna and garlic. Germanium is a non-metallic element, which can exist in valence states of 2 and 4. Clinical trials and use in private practices for more than a decade have demonstrated organic germanium's efficacy in treating serious disease including cancer, arthritis and senile osteoporosis. But it was rarely reported that inorganic germanium has biological properties. STB-BM contains mineral complex, rare earth elements and a little amount of Inorganic germanium. The experiment was carried out the anti-obesity effect. To investigate anti-obesity effect of STB-BM, we measured the effect of body weight, fat weight (subcutaneous fat, epididymal fat, visceral fat, kidney fat and total fat) and serum biochemical level in rats fed high fat diets. STB-BM 35 mg/kg suppressed the increasing ratio of body weight, epididymal fat weight, visceral fat weight, total fat weight, triglyceride and LDL-cholesterol (p<0.05).

• 여성건강간호학회지
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• 제3권2호
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• pp.192-207
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• 1997

This study aims at examining relationships between perceived body shape, body image and health complaints among 88 women registered at a facility for managing body shape, which leads to adequate management of obesity in women for healthy lives. The survey was conducted by using a questionnaire consisted of 12 items of general characteristics and interests for weight control, 47 items of body image, and 57 items of Cornell Medical Index(CMI). The data were analyzed by using mean standard deviation, ANOVA, and Pearson correlation coefficient. The results are following. 1. The means of age, body weight, height of the women were 27.02 years, 56.02 years, 56.03kg, 161.71cm, respectively. The level of obesity by body shape was 47.7% for standard type, 26.2% for slim type, 26.1% for fat type. Those women graduated from high school or higher education institutions were 97.7%. 2. More than 70% of the subjects perceived their weight as overweight, while 26.1% of the women were fat according to the level of obesity. Ninety percent of the subjects were not satisfied with their body shape. 3. Body weight increased most during middle and high school days. The women became interested in weight control through talks with friends(35.2%), influence of mass communication(34.1%), and social custom(22.7%). As to the method of weight control, subject's own judgement(54.5%) revealed highest percentage, whereas only 20% of the subjects adopted prescriptions of experts for weight control or of doctors. Those who had side reactions from weight control were 30.7%. High percentages of the women reported the decrease the amount of eating(54.5%), the increase the amount of exercise(27.3%) as the effective methods of weight control. 4. The score of body image differed significantly by the perceived body shape : the score was highest in the perceived standard type. 5. The level of health complaints did not differ by the perceived body shape. In relation to the level of obesity, physical health complaints were high in the groups of very slim type and of very fat type, while mental health complaints were high in the groups of very slim type and of fat type. 6. Very high correlations were observed between the perceived body shape and body image and between physical health complaints and mental health complaints.

• 한방비만학회지
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• 제2권1호
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• pp.37-42
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• 2002

Objectives: To compare the body composition of the postpartal female weight-gained over the recommended during pregnancy with that of normal female with same age. female diagnosed as obesity and postpartal female weight-gained within the recommended during pregnancy. Methods: From Apr. 1. 2001 to Feb. 28. 2002, there were 745 delivery in Dept. of Obstetrics & Gynecology, Kyung-Hee Medical Center. 32 mothers of them wanted to be investigated about the weight gain during their pregnancy. We excluded 12 persons who had gained within the recommended weight$(15{\beta}{\prod})$ and had diagnosed as the diseases inducing pathologic edema, preeclamsia. gestational heart or renal diseases, for example. In 2 days after delivery(nomal) or 5 days after(Caesarean section) we analysed the body composition of 20 persons. Results: 1. Compared with normal female, body weight, body mass index and body fat of the women gained over the recommended were increased and there made alternation to the increase of the percentage of body fat or the decrease of the percentage of lean body mass. 2. Compared with obese women who had same body mass index, the women gained over the recommended showed a little increase of body fluid, protein and mineral, but had a little decrease of the percentage of body fat. 3. The percentages of body fat increased with the women gained over the recommended, the women gained within the recommended and the obese women in order. This could imply the relation between the pregnancy, weight gain during pregnancy and the obesity. 4. The weights before pregnancy were same in the women gained over the recommended and the women gained within the recommended. But the weights just after delivery kept the gap happened during pregnancy between them and its main cause was the increase of body fat. Conclusions : The women gained over the recommended during pregnancy experienced the chage of body composition and its main cause was the increase of body fat. So compared with the women gained within the recommende, postpartal obesity more frequently could happen.

• 한국임상약학회지
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• 제28권3호
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• pp.204-215
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• 2018

Background: In this systematic review and meta-analysis, the effect of metformin on weight loss was assessed to determine whether metformin should be recommended for the prevention or treatment of weight gain in patients receiving antipsychotic medication for the treatment of schizophrenia or schizoaffective disorder. Methods: The PubMed, Embase, and Cochrane Library databases were searched for all published randomized controlled trials (RCTs) from inception to June 2018. In addition, the references of relevant articles were also examined. Using Review Manager 5, the pooled estimates of the weighted mean difference (WMD) of the changes in body weight and body mass index (BMI) and the corresponding 95 % confidence intervals (CIs) were calculated. Results: The meta-analysis included 15 RCTs. The pooled analysis showed that compared with placebo, metformin led to significant reductions in body weight (WMD: -2.09, 95% CI: -2.59, -1.60; p<0.00001) and BMI (WMD: -0.90, 95% CI: -1.08, -0.72; p<0.00001). The effect of metformin on weight loss was greater in patients receiving olanzapine than in patients receiving clozapine (body weight, WMD: -2.39, 95% CI: -3.76, -1.02; p=0.0006 for olanzapine; -1.99, 95% C: -3.47, -0.51; p=0.009 for clozapine; BMI, WMD: -1.15, 95% CI: -1.74, -0.57, p=0.0001 for olanzapine; WMD: 0.76, 95% CI: -1.23, -0.28; p=0.002 for clozapine). Conclusion: Metformin can be recommended to manage olanzapine-induced weight gain in patients with schizophrenia or schizoaffective disorder. The magnitude of the reductionss in body weight and BMI implieds that the use of metformin to attenuate olanzapine-induced weight gain can minimize the risk of coronary heart disease.

• Asian-Australasian Journal of Animal Sciences
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• 제32권7호
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• pp.930-938
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• 2019

Objective: Estimate genetic parameters, the rate of inbreeding, and the effect of inbreeding on growth and egg production traits of a Thai native chicken breed Lueng Hang Kao Kabinburi housed under intensive management under a tropical climate. Methods: Genetic parameters were estimated for weight measured at four weekly intervals from body weight at day 1 (BW1D) to body weight at 24 weeks (BW24) of age, as well as weight at first egg, age at first egg (AFE), egg weight at first egg, and total number of eggs (EN) produced during the first 17 weeks of lay using restricted maximum likelihood. Inbreeding depression was estimated using a linear regression of individual phenotype on inbreeding coefficient. Results: Direct additive genetic effect was significant for all traits. Maternal genetic effect and permanent environmental hen effects were significant for all early growth traits, expect for BW24. For BW24, maternal genetic effect was also significant. Permanent environmental hen effect was significant for AFE. Direct heritabilities ranged from 0.10 to 0.47 for growth traits and ranged from 0.15 to 0.16 for egg production traits. Early growth traits had high genetic correlations between them. The EN was lowly negatively correlated with other traits. The average rate of inbreeding for the population was 0.09% per year. Overall, the inbreeding had no effect on body weight traits, except for BW1D. An increase in inbreeding coefficient by 1% reduced BWID by 0.09 g (0.29% of the mean). Conclusion: Improvement in body weight gain can be achieved by selecting for early growth traits. Selection for higher body weight traits is expected to increase the weight of first egg. Due to low but unfavorable correlations with body weight traits, selection on EN needs to be combined with other traits via multi-trait index selection to improve body weight and EN simultaneously.