• Title/Summary/Keyword: Body fluids

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악성 삼출액에서 E-Cadherin 발현의 유용성 (Usefulness of E-Cadherin Expression in Malignant Effusion)

  • 임성직;김교영;김윤화;박용구;양문호;원남희;이주희
    • 대한세포병리학회지
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    • 제10권2호
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    • pp.121-126
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    • 1999
  • 체강액 내의 악성 종양세포와 중피세포의 구분이 종종 어려우나 환자의 치료나 종양의 임상기 결정에 큰 영향을 미치기 때문에 정확히 감별하는 것이 매우 중요하다. E-cadherin은 상피세포에서 표현되는 유착단백질이다. 본 연구에서는 체강액의 세포학적 검사에서 악성세포의 표지자로서 E-cadherin의 유용성을 알아보기 위하여 세포검사후 조직검사로 진단을 확인한 33예를 대상으로 체강액으로부터 만든 세포 블록에 대하여 E-cadherin에 대한 면역세포화학염색을 시행하였다. 33 예의 세포학적 진단은 선암종 25예, 비정형세포 8예였다. 선암종으로 진단하였던 25 예중 21예(84%)에서 E-cadherin 에 양성이었다. 비정형세포라고 진단하였던 8예중 6예에서 음성이었으며 양성으로 염색된 2예는 조직학적 검사로 전이성 암종임을 확인하였다. 반응성 중피세포나 염증세포는 모두 음성이었다. 민감도와 특이도는 각각 84%와 75%였다. 결론적으로 E-cadherin은 체강액에서 악성 종양세포와 반응성 중피세포와의 구분에 유용한 보조적인 표지자이다.

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한우에 있어서 생식기관액 중 지방산 조성과 조성율 (Fatty Acid constituents and Relative Compositions of Reproductive Tract Fluids in Korean Native Cows)

  • 신원집;정진우;최광수;신수길
    • 한국수정란이식학회지
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    • 제15권2호
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    • pp.147-156
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    • 2000
  • To investigate fatty acid constituents and relative compositions in the fluid of the follicles, oviducts, uterine body and uterine body in Korean native cow, the fluids of the reproductive tract were analyzed using gas chromatography. The samples were taken from various reproductive tract of 23 Korean native cows. q. Caprylic acid (C8:0), myristic acid(C14:0), palmitic acid(C16:0), palmitoleic acid(C16:1), stearic acid(C18:0), oleic acid(C18:1), linoleic acid(C18:2), arachidonic acid(C20:4) were found in the reproductive tracts of the cows, which made 8 kinds of fatty acid in total. 2. Palmitic acid, oleic acid, stearic acid were predominant with 35.67%, 24.98% and 17.52%, respectively. while low levels of fatty acids(<5%) were myristic acid, palmitoleic acid and caprylic acid with 1.75%, 1.28% and 2.69%, respectively. 3. Two kinds of polyunsaturated fatty acids, linoleic acid arachidonic acid were found in the reproductive tracts of cows. 4. Palmitic acid among saturated fatty acids and oleic acid among unsaturated fatty acids were the highest level in all of the reproductive tracts. 5. The Highest level of arachidonic acid was found in the uterine horn. 6. The sum of the palmitic acid and oleic acid were 61.72%, 63.72%, 57.66% and 57.65% for the fluid of follicle, oviduct, uterine horn and uterine body of the cows, respectively. 7. The relative compositions of palmitic acid, palmitoleic acid and caprylic acid were higher during the luteal phase than during the follicular phase. 8. The relative compositions of arachidonic acid was higher during the follicular phase in the fluid of uterine horn and uterine body of the cows. 9. The long chain fatty acid, the palmitic acid, stearic acid, oleic acid and linoleic acidshowed higher relative compositions during the follicular phase(86.49%∼95.51%) than during the luteal phase(85.64%∼88.93%).

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익형 동체의 하강기류(Down-wash)가 공기역학적 특성에 미치는 영향에 관한 수치해석연구 (A NUMERICAL STUDY ON THE EFFECT OF DOWN-WASH OF A WING-BODY ON ITS AERODYNAMIC CHARACTERISTICS)

  • 윤경호;김철호
    • 한국전산유체공학회지
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    • 제18권3호
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    • pp.8-13
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    • 2013
  • Drag reduction of a running vehicle is very important issue for the energy savings and emission reduction of its power train. Especially for a solar powered electric vehicle, the drag reduction and weight lightening are two serious problems to be solved to extend its driving distance under the given energy condition. In this study, the ground effect of an airfoil shaped road vehicle was studied for an optimum body design of an ultra-light solar powered electric vehicle. Clark-Y airfoil type was adopted to the body shape of the model vehicle to reduce aerodynamic drag. From the study, it was found that the drag of the model vehicle was reduced as the height(h) between ground and the lower surface of the model vehicle was decreased. It is due to the reduction of the down-wash decreasing the induced drag of the vehicle. The lift was also decreased as the height decreased. It is due to the turbulent boundary layer developed beneath the vehicle body. The drag is classified into two types; the form and friction drag. The fraction of form drag to friction one is 76 to 24 on the model vehicle. As the height(h) of the model vehicle from the ground surface increases the form drag also increases but the friction drag is in reverse.

자성유체의 밀폐공간내의 열전달 특성에 관한 실험적 연구 (Experimental Analysis on the Heat Transfer Characteristics of Magnetic Fluids in a Cubic Cavity)

  • 박정우;서이수;전철호;박길문
    • 한국자기학회지
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    • 제13권3호
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    • pp.127-132
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    • 2003
  • 자성유체의 자연대류는 부력 이외에 자기체적력이 존재하기 때문에 뉴턴유체와 다르다. 본 연구에서는 좌측 및 우측 벽면이 고온 및 저온으로 설정된 정방형 케비티 공간내에서 자성유체의 자연대류를 실험하였다 실험은 열전대에 의한 온도측정과 감온액정에 의한 가시화를 실시하였다. 그 결과 케비티 공간내 자성유체의 전열특성 및 외부에서 가하는 자장의 방향과 세기에 따라 자연대류가 제어됨을 알 수 있었다.

CFD를 이용한 유도탄 power-on 기저항력 해석 (NUMERICAL SIMULATION OF THE POWER-ON BASE DRAG OF A MISSILE BODY)

  • 최재혁;이은석;이광섭
    • 한국전산유체공학회지
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    • 제20권2호
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    • pp.16-22
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    • 2015
  • The pressure is generally lower than that of the freestream at the base of a missile body due to the energy loss by the flow separation around the edge of the base. The base pressure changes in the presence of the thrust jet due to the interaction between the base flow of the missile and the jet flow. In this study, behavior of the missile base pressure by the change of the jet exit pressure and the freestream condition is investigated using the CFD(Computational Fluid Dynamics) method. Effects of the grid type and the freestream condition are tested. The results are compared with the semi-empirical predictions and the flight test data. The CFD results agree well with the flight test data. The semi-empirical predictions overestimate the base pressure when jet thrust is strong for low freestream speed.

동유체력 계산을 이용한 수중운동체의 횡동요 계수 변화 예측 (ESTIMATION OF ROLL COEFFICIENT OF UNDERWATER VEHICLE USING A CALCULATION OF HYDRODYNAMIC FORCES)

  • 김태우;강태진;박원규;정철민
    • 한국전산유체공학회지
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    • 제20권2호
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    • pp.81-87
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    • 2015
  • For Underwater vehicles, Unwanted roll excursions are inevitable as they are caused by induced propeller torque, disturbances, and banking motion during turns. To estimate the manoeuvring performance of underwater vehicle, it is necessary to obtain the roll coefficient of body. This paper was covered estimation of roll coefficient of underwater vehicle using STAR-CCM+, commercial CFD(Computational Fluid Dynamics) code. The RANS equations for incompressible fluid flows was solved numerically by using a finite volume method. An MRF(Moving Reference Frame) Method was Also adopted for rotations of body. For the validation, the flow around a DARPA SUBOFF bare hull model was simulated and good agreement with experiments was obtained. And Pure roll coefficients were calculated and campared with the experimental data which were presented by Seoul National University. Finally, an underwater vehicle model with propeller was simulated and analyzed for estimation of roll coefficient variation caused by induced propeller torque.

2층으로 성층화된 풀 내에서의 자연대류 열전달과 고화현상에 대한 연구 (Analysis of Natural Convection Heat Transfer and Solidification of a Two-Layered Pool)

  • 김종태;강경호;김상백;김희동
    • 한국전산유체공학회지
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    • 제6권1호
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    • pp.1-13
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    • 2001
  • The natural convection heat transfer and solidification in a stratified pool are studied. The flow and heat transfer characteristics in a heat generating pool are compared between single-layered and double-layered pools. And local Nusselt number distributions on outer walls are obtained to consider thermal loads on a vessel wall. The cooling and solidification of Al₂O₃/Fe melt in a hemispherical vessel are simulated to study the mechanism of heat transfer and temperature distribution. A unstructured mesh is chosen for this study because of the non-orthogonality originated from the boundaries of double-layered pool. Interface between the layers is modeled to be fixed. With this assumption mass flux across the interface is neglected, but shear force and heat flux are considered by boundary conditions. The colocated cell-centered finite volume method is used with the Rhie-Chow interpolation to compute cell face velocity. To prevent non-physical solutions near walls in case body force is large the wall pressure is extrapolated by the way to include body force. The numerical solutions calculated by current method show that averaged downward heat flux of the double-layered pool increases compared to single-layered pool and maximum temperature occurs right below the interface of the layers.

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전산유체역학 기법을 이용한 물고기 유영에 관한 연구 (A STUDY ABOUT FISH LOCOMOTION USING COMPUTATIONAL FLUID DYNAMICS)

  • 김소희;정용수;권오준
    • 한국전산유체공학회지
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    • 제19권2호
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    • pp.99-107
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    • 2014
  • The aim of the present study is to investigate the flow interference between two adjacent undulating fish-like body, and its effect on the undulating propulsion. For this purpose, unsteady two dimensional incompressible flow calculations were conducted using an unstructured mesh flow solver, coupled with an overset mesh technique. To deal with mesh deformation due to fish locomotion, spring analogy is utilized. The fish body used in the simulation is constructed from the NACA0012 airfoil. The study indicates that the propulsion of undulating fish is proportional to frequency and wavelength of the midline oscillation when there is no adjacent fish. It also reveals that average thrust was increased when the vortex shedding from the tail was conserved well and pressure difference between upper and lower sides of the fish was magnified due to flow interference. From this study, which relative position and phase difference of locomotion between two fishes can generate maximum thrust was known among six different cases.