• Journal of the East Asian Society of Dietary Life
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• v.13 no.6
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• pp.561-567
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• 2003

As an attempt to develop new functional health beverage by using medicinal herb, Artemisia capillaris, we investigated the effect of scopoletin in Artemisia capillaris on vessel and regional cerebral blood flow (rCBF) of rats ingesting health drink prepared with Artemisia capillaris extracts and various ingredients. Artemisia capillaris extract decreased the vessel contraction and increased rCBF significantly. The extracts were grouped by heat temperature and mixed ratio and tested their respective characteristics. Then each condition was combined and produced the most effective one. The drink produced consisted of Artemisia capillaris extract 42%, honey 9.8%, citric acid 0.035%, cyclodextrin 1.47% and water. Brix, pH and acidity of the product were 9.2, 4.4 and 0.04%, respectively, This drink scored to have highest level on overall acceptance by the sensory evaluation. The above results showed that development of such functional beverage using Artemisia capillaris can be used as a functional material improving blood circulation in beverage industry.

• Proceedings of the Materials Research Society of Korea Conference
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• 2010.05a
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• pp.45.1-45.1
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• 2010

In this experiment, artificial blood vessel was fabricated from electro-spun PU/PCL. To assist with endothelial growth, PU/PCL surface was coated with the RGD peptide. To prevent a clot of blood, anti-thrombus agent was loaded to the fibrous mat and values were reflected through FT-IR data. In vitro study, SEM and MTT data showed that the component was of excellent biocompatibility and cell proliferation. In in vivo study, the artificial blood vessel was implanted in a dog's artery. The results of the CT scan, ultrasound and H&E staining showed that artificial blood vessel was excellent for artery replacement applications.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.22 no.1
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• pp.45-49
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• 2013

It is important to have a well developed strain energy function in order to understand the mechanical behavior of biomaterial like the blood vessel of artery. However, since it is not possible to have a complete form of strain energy function of artery, theoretical framework describing the behaviour of Rubber-like material which is similar to blood vessel is applied to infer useful forms of strain energy function of biomaterial. Based on Chuong-Fung model and Mooney-Rivlin model, material parameters are estimated based on experimental data. From the results, it can be inferred that the estimated parameters can be used to explain the difference of mechanical characteristics between normal vessel and vessel with stent.

• Korean Journal of Digital Imaging in Medicine
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• v.13 no.1
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• pp.39-48
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• 2011

Uses a Tomographic scan image and Table Object Distance(TOD) price after measuring, uses accuracy and usability of blood vessel diameter(Vessel Diameter) measurement under comparison evaluating boil TOD Calibration. The patient who enforces Prosecuting Attorney abdomen Tomographic scan in the object the superior mesentery artery uses PACS View from abdomen fault image and from blood vessel diameter and the table measures the height until of the blood vessel. Uses Angio Catheter from Angiography(5 Fr.) and enforces is measured from PACS View the height until of the table which and the blood vessel at TOD Calibration price and the size of the superior mesentery artery inputs measures an superior mesentery artery building skill. Catheter Calibration input Agnio Catheter where uses in Angiography the size of the superior mesentery artery at Catheter Calibration price and they measure. Produced an accuracy from monitoring data and comparison evaluated. The statistical program used SPSS. TOD Calibration accuracy was 96.53%, standard deviation is 0.03829. Catheter Calibration accuracy of 92.91%, standard deviation is 0.05085. Represents a statistically significant difference(p = 0). According to age and gender was not statistically significant(p > 0.05). TOD Calibration correlation coefficient R-squared of 88.8%, Catheter Calibration of the R-squared is 75.5%. High accuracy of both methods. Through this study, CT images using the measured distance between the table and the Object, TOD Calibration accuracy higher than two Catheter Calibration was measured. TOD and Catheter Calibration represents a statistically significant difference(p = 0).

• 한국전산유체공학회:학술대회논문집
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• 2004.10a
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• pp.203-206
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• 2004

In this study, a numerical analysis has been performed for a three-dimensional pulsatile blood flow associated with the elastic blood vessel and curved bileaflet for multiple cycles in terms of fluid-structure interaction. Here, blood has been assumed as a Newtonian, incompressible fluid. Pressure profiles have been used as boundary conditions at the ventricle and the aorta. From this analysis, the motion of the leaflet has been observed with fluttering phenomenon and rebound, and the flow fields of blood have been obtained with recirculation and regurgitation. The results can contribute to the development of design methodology for the curved bileaflet mechanical heart valve.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.6
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• pp.607-613
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• 2014

In a previous study, we have shown that mulberry leaves (Mori Folium) extract MFE) and its compounds have the antioxidant effect in human red blood cells. However, the possible effect of MFE and its compounds on improvement of blood flow were not reported. Therefore, the aim of this study is to investigate the effects of MFE and its compounds on improvement of blood flow in a rat model of topical ferric chloride ($FeCl_3$)-induced carotid artery damage. The $FeCl_3$ treatment seriously damaged the carotid artery: the walls of the artery, blood flow rate, blood vessel diameter, blood vessel area and blood flow amount. However, administration of MFE or its compound has ameliorated the blood flow and suppressed thrombus in blood vessels. Moreover, the concentrations of serum total cholesterol, triglycerides, and LDL cholesterol in the MET and its compound groups were remarkably reduced in comparison to the control group, and HDL cholesterol concentration was higher in the MET and its compound groups than in the control group. These results suggest that MFE and its compounds ameliorate the thrombosis against blood vessel damage.

• Journal of the Korean Applied Science and Technology
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• v.34 no.4
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• pp.756-768
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• 2017

The subjects for the study were twenty four obese women(50's) composed of the exercise group(n=12) and to a "no exercise" control group(n=12). The variables of health-related fitness, blood pressure, and blood vessel elasticity where measured in all the subjects before the start of the training program and after at the end of the 8 weeks circuit training. The test data were analyzed by t-test, paired t-test, and alpha level of p<.05 was set for all tests of significance. Health-related fitness was exercise group, the BMI had significantly decreased, and the 20m shuttle run, sit-ups and sit-and-reach had significantly increased. Blood pressure was exercise group, the systolic blood pressure, and diastolic blood pressure had significantly decreased. Also, after the circuit training program, the exercise group had significantly higher diastolic blood pressure than did the control group. blood vessel elasticity was exercise group, the blood vessel elasticity had significantly decreased. And exercise group had significantly higher diastolic blood vessel elasticity than did the control group. In conclusion, BMI, systolic blood pressure, and diastolic blood pressure had significantly decreased, but 20 m shuttle run, sit-ups and sit-and-reach had significantly increased in the combined exercise group after the 8 weeks circuit training. Therefore, regular and continuous circuit training were effective in improving the body composition, blood pressure, blood vessel elasticity and health-related fitness.

• Journal of Korea Multimedia Society
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• v.19 no.2
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• pp.224-232
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• 2016

The methodology to visualize the shape of blood vessel and its blood flow have been attracting as a very interesting problem to forecast and examinate a disease in thrombus precursor protein. May previous visualization researches have been appeared for designing the blood vessel and also modeling the blood flow using a doppler imaging technique which is one of nondestructive testing techniques. General visualization methods are to depict the blood flow obtained from doppler effects with fragmentary stream lines and also visualize the blood flow model using volume rendering. However, these visualizeation techniques have the disadvantage which a set of small line segments does not give the overall observation of blood flows. Therefore, we propose a visualization system which reconstruct the continuity of the blood flow obtained from doppler effects and also visualize the blood flow with the vector field of blood particles. This system will use doppler phase difference from medical equipments such as OCT with low penetration and reconstruct the blood flow by the curvature estimation from vector field of each blood particle.

• Journal of Gastric Cancer
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• v.10 no.2
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• pp.55-62
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• 2010

Purpose: We evaluated the clinicopathological charicterics and prognostic impacts of lymphatic vessel invasion in gastric cancer without lymph node involvement. Materials and Methods: Among 1,795 patients who underwent gastric surgery with gastric cancer at the department of surgery, Hanyang university college of medicine from June 1992 to March 2009, we retrospectively evaluated 890 patients with lymph node negative gastric cancer. Results: The lymphatic vessel invasion correlated significantly with tumor stage, age, tumor size, perineural invasion and operation method. The survival rates were only significantly different between the patients with and without lymphatic vessel invasion in patients with stage Ia (P=0.036). Univariate and multivariate analysis demonstrated that blood vessel invasion and preoperative serum CEA level were significant factor influencing the survival rate in lymph node negative gastric cancer patients with lymphatic invasion. Conclusions: In patients with lymph node negative gastric cancer, the survival rate is significantly lower in those with lymphatic vessel invasion than in those without. Especially, in patients with stage Ia gastric cancer, the survival rates is significantly different between those with and those without lymphatic vessel invasion. Blood vessel invasion and preoperative serum CEA level is an adverse prognostic indicator in patients with stage Ia gastric cancer with lymphatic invasion. Thus we should consider further adjuvant therapies in case of need and need to show more concern to identify gastric cancer patients early at risk for recurrence.

• International Journal of Vascular Biomedical Engineering
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• v.2 no.1
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• pp.25-30
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• 2004

Catheters are used to measure translesional pressure gradients in the stenosed coronary arteries. Uses of catheters during coronary angioplasty cause flow obstructions. A narrowed flow cross section with catheter effectively introduced a tighter stenosis than the enlarged residual stenoses after balloon angiplasty. Catheters in blood vessels cause pressure gradient rise and blood flow drop during the measurements. In this study, three dimensional computer simulations are conducted to investigate the flow blockage effects due to the catheter obstructions during the coronary angioplasty. The computer simulation models are generated by the data, which are measured by coronary angiogram, and the blood is treated as non-Newtonian fluid. The velocity, pressure, and wall shear stress variations are observed for the estimate of damages of blood vessel. This study is also extended to investigate the effects of stenotic vessel size, and shape and catheter size and location.