• 대한신경과학회지
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• 제36권4호
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• pp.302-309
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• 2018

Background: Although orthostatic hypotension (OH) and cognitive impairment (CI) are common non- motor symptoms of Parkinson's disease (PD), the relationship between OH and CI remains to be clarified. This study was aimed to investigate the relationship between OH and CI in PD. Methods: We recruited 192 patients who were diagnosed as PD based on the UK Brain Bank diagnostic criteria. The Hoehn & Yahr stages were ranged I to III and patients underwent extensive clinical evaluation, including brain magnetic resonance imaging (MRI) for cerebral white matter hyperintensity (WMH), tilt table test, the Korean version of Montreal Cognitive Assessments and the Korean version of Mini-Mental Status Examination in one month from the first clinic visit. The participants were divided into two groups according to the presence of OH (OH+ vs. OH-) and cognitive function (cognitive normal, CN vs. CI), respectively. Results: Significant relationship between OH and cognitive function (p=0.04) was found in our patients. The patients with OH+ had higher risk of CI by 2.6 times than that of OH- patients. Maximum heart rate change during tilt table test was correlated with cognitive function and white matter changes, whereas blood pressure change during tilt table test showed no correlation with those parameters. Conclusions: There was significant relationship between OH and CI in PD. Therefore, PD patients with either symptom may need periodic evaluation and proper management for OH and cognitive functions.

• 한국융합학회논문지
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• 제12권8호
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• pp.309-315
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• 2021

소나무 수피에서 추출한 Pycnogenol은 항균활성과 항산화 효과가 뛰어난 성분으로 항염, 혈압조절기능, 면역조절, 암세포 성장억제 등 다양한 의학적 효능과 함께 천연 소염제로 응용되고 있지만 화장품 관련 연구는 미비한 상황이므로 본 연구는 Pycnogenol 성분이 피부에 미치는 효과를 임상학적 접근한 연구이다. Pycnogenol 성분 첨가, 무첨가한 화장품을 각 각 10명의 임상자가 6주간 사용하게 한 후 피부 상태 변화를 살펴보았으며 모공의 감소, 눈가주름의 감소, 처진모공의 개수와 각도의 감소, 색소침착이 감소하는 효과가 있었다. 그러므로 Pycnogenol 성분을 함유한 화장품은 노화피부에서 나타나는 피부 문제를 개선하는 효과가 있다.

• Journal of Platform Technology
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• 제9권1호
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• pp.40-45
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• 2021

COVID-19 펜데믹으로 인하여 우리의 일상은 많은 변화를 가지고 왔다. 이로 인한 사회적거리두기와 같은 공중보건 조치로 인하여 COVID-19의 확장을 줄이는 데는 필수적이나, 동시에 우울증, 불안장애, 우울장애, 외상 및 스트레스 관련 장애 등에 노출이 되고 있다. 본 논문에서는 생체신호를 실시간으로 측정이 가능한 Smart Watch 디바이스를 기반으로 한 ECG와 PPG 측정을 통하여 HRV 데이터 및 스트레스 지수 확인이 가능한 Application을 개발하였다. 개발된 Application의 경우 실시간으로 Heart Rate를 측정하여 표시 하였으며, 걸음 수와 칼로리, 총 운동 거리를 측정하여 기본적인 운동정보를 전달하였고, 측정하기 프로그램으로 혈압, 심박수, HRV 데이터를 블루투스 기반으로 원활히 전달 하였다. 이를 통해 스스로 정신건강 관리를 할 수 있는 IoT 스마트 스트레스 케어 Application이 스트레스 및 우울 외상 장애 환자에게 도움이 될 것이라 생각한다.

• 한국산림과학회지
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• 제109권4호
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• pp.544-552
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• 2020

본 연구는 국립산림치유원에서 2019년 진행된 장기체류 산림치유프로그램 「숲 속 힐링스테이」에 참가한 49명을 대상으로, 참여 전·후 설문조사 및 혈압, 체성분, HRV 등 신체변화를 측정하여 프로그램의 효과성을 분석했다. 연구결과, 장기체류 산림치유프로그램 참여 후에 참여자의 부정감정이 통계적으로 유의하게 감소하였고, 자율신경 균형도는 통계적으로 유의하게 증진되어 긍정적인 효과를 확인할 수 있었다. 병력 유무에 따른 체력측정 변화를 살펴본 결과 악력 및 제자리높이뛰기 증가 정도가 통계적으로 유의한 차이가 있었으며, 병력이 있는 사람들이 병력이 없는 사람들에 비해 증진 효과가 더 높게 나타났다. 본 연구에서는 단기형 프로그램 효과검증에서 벗어나 6박7일 장기체류 형태의 산림치유 효과성을 확인한 것에 그 의의가 있다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제21권1호
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• pp.61-69
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• 2021

Background: Inferior alveolar nerve block (IANB) using lidocaine 2% is commonly used for anesthetizing primary mandibular molars; however, this technique has the highest level of patient discomfort compared to other local anesthesia techniques. Therefore, alternative anesthesia techniques are necessary. The aim of this study was to evaluate the efficacy of a single buccal infiltration of 4% articaine with IANB using 2% lidocaine, for the bilateral extraction of primary mandibular molars. Methods: The present study was conducted on 30 patients aged between 6 and 9 years, who required the extraction of bilateral primary mandibular molars. The patients were randomly divided into two groups as follows: In the first session, Group A received IANB with lidocaine 2% and group B received infiltration with articaine 4%. In the second session, another injection method was performed on the opposite side. The Wong-Baker Facial Pain scale (WBFPS), Face Leg Activity Cry, and Consolability (FLACC), and physiologic parameters were used to assess pain perception. Results: The independent t-test showed no statistically significant difference in blood pressure and heart rate before and after extraction (P > 0.05). The mean FLACC index in the lidocaine and articaine groups was 0.89 and 1.36, respectively; there was no statistically significant difference between them (P > 0.05). According to the results of the chi-square test, there was no statistically significant difference between the groups for WBFPS (P > 0.05). Conclusion: The articaine infiltration technique may be an alternative to the IANB for the extraction of primary mandibular molars.

• Nutrition Research and Practice
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• 제15권1호
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• pp.80-94
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• 2021

BACKGROUND/OBJECTIVES: Recent studies have reported chocolate consumption has beneficial effects on blood pressure, obesity, and dyslipidemia, which are components of metabolic syndrome (MetS). However, evidence regarding these relationships in Asia is limited. The aim of this study was to investigate relations between chocolate consumption and MetS in Korea. SUBJECTS/METHODS: Study subjects were 6,982 adults aged 19-64 years free of major chronic diseases that participated in the 2014-2016 Korea National Health and Nutrition Examination Survey. Information on chocolate consumption was obtained using food frequency questionnaires. For primary analysis, subjects were divided into two groups: non-consumer (n = 3,741, 53.6%); consumer (n = 3,241, 46.4%). In order to investigate dose-response effects on MetS, chocolate consumers were divided into quartiles based on amounts consumed: Q1 (n = 789, 24.3%); Q2 (n = 837, 25.8%); Q3 (n = 863, 26.6%); Q4 (n = 752, 23.2%) in second analysis. RESULTS: Chocolate consumers; 1) were more physically active(P < 0.0001); 2) less likely to smoke(P < 0.0001); 3) paid more attention to food nutrition labels (P < 0.0001), and 4) had healthier dietary patterns, that is, they consumed vegetables, fruits, and dairy products more frequently(P < 0.0001) than non-consumers. Furthermore, chocolate consumers had a 30% lower risk of MetS (odds ratio, 0.70; 95% confidence interval, 0.58-0.86; P = 0.0005). However, dose-response effects between chocolate intake and MetS was not found by secondary analysis after excluding non-consumers. CONCLUSIONS: In conclusion, chocolate consumers had healthier lifestyles and dietary patterns and a lower prevalence of MetS than non-consumers, as determined by our primary analysis. Although dose-response effects were not found to be significant among chocolate consumers during secondary analysis, the patterns were partially similar. This cross-sectional finding shows chocolate consumption does not increase the risk of MetS. The prospective studies and intervention trials in Korea are needed to confirm this cross-sectional finding.

• Journal of Chest Surgery
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• 제54권3호
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• pp.200-205
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• 2021

Background: Various methods have been used to reduce postoperative pain after thoracic surgery. However, these methods may affect the patient's respiratory response and delay recovery from anesthesia. We aimed to evaluate the effects of fentanyl and remifentanil during extubation after video-assisted thoracic surgery (VATS). Methods: This study included 45 randomly-selected male patients who underwent VATS for pneumothorax between July 2011 and August 2012. We divided the participants into 3 groups: the F group, which received a bolus injection of 1.0 ㎍/kg of fentanyl; the R1 group, which received a 0.04 ㎍/kg/min remifentanil infusion; and the R2 group, which received a 0.08 ㎍/kg/min remifentanil infusion. Hemodynamics, pain, cough, consciousness level, and nausea were assessed for each group. Results: The number and severity of coughs were lower in the R1 and R2 groups than in the F group, and there were no differences between the R1 and R2 groups. Respiratory depression and loss of consciousness were not observed in any of the patients, and there were no differences in hemodynamics. Conclusion: In comparison with fentanyl, remifentanil did not result in a wide fluctuation of blood pressure and heart rate upon emergence from general anesthesia. Moreover, remifentanil contributed to cough suppression and postoperative pain control. Remifentanil seems to be a safe and effective analgesic after VATS.

• Journal of Dental Anesthesia and Pain Medicine
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• 제21권2호
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• pp.155-165
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• 2021

Background: This study aimed to assess the course of anxiety and pain during lower third molar (LTMo) surgery and explore the role of mobile and single-channel electroencephalography under clinical and surgical conditions. Methods: The State-Trait Anxiety Inventory (STAI), Corah's Dental Anxiety Scale (DAS), and Interval Scale of Anxiety Response (ISAR) were used. The patient self-rated anxiety (PSA), the pain felt during and after surgery, EEG, heart rate (HR), and blood pressure (BP) were assessed. Results: The Attention (ATT) and Meditation (MED) algorithms and indicators evaluated in this study showed several associations. ATT showed interactions and an association with STAI-S, pain during surgery, PSA level, HR, and surgical duration. MED showed an interaction and association with DAS, STAI-S, and pain due to anesthesia. Preclinical anxiety parameters may influence clinical perceptions and biological parameters during LTMo surgeries. High STAI-Trait and PSA scores were associated with postoperative pain, whereas high STAI-State scores were associated with more pain during anesthesia and surgery, as well as DAS, which was also associated with patient interference during surgery due to anxiety. Conclusions: The findings suggest that single-channel EEG is promising for evaluating brain responses associated with systemic reactions related to anxiety, surgical stress, and pain during oral surgery.

• 한국농촌간호학회지
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• 제15권2호
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• pp.49-56
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• 2020

Purpose: This descriptive correlational study was done to analyze the relationship between social support and self-care in hypertensive patients aged 30 years or older. Methods: Data were collected from April 09 to April 16, 2020 through an online survey (Naver Form) at Internet cafes and SNS Eighty 80 adults aged 30 or older who had been diagnosed with high blood pressure at a medical institution participated in the study. Data were analyzed using t-test, one-way ANOVA, Scheffé's test and Pearson correlation coefficients with SPSS statistics 26.0. Results: The study results showed that social support for hypertensive patients was significantly higher for men (t=-2.17, p=.033), according to religious status (t=-2.33, p=.023), and the number of people in the household (F=6.05, p=.001). In addition, there was a significant positive correlation between social support and hypertensive self-care (r=.24, p=.036). Conclusion: The results confirm that the social support of patients with hypertension is related to self care for hypertension management. As the number of elders and single-person households who cannot manage their health well increases, it is necessary to establish a long-term and continuous social support system for these clients.

• Journal of Trauma and Injury
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• 제33권4호
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• pp.207-218
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• 2020

The following recommendations are presented herein: All trauma patients admitted to the resuscitation room should be constantly (or periodically) monitored for parameters such as blood pressure, heart rate, respiratory rate, oxygen saturation, body temperature, electrocardiography, Glasgow Coma Scale, and pupil reflex (1C). Chest AP and pelvic AP should be performed as the standard initial trauma series for severe trauma patients (1B). In patients with severe hemodynamically unstable trauma, it is recommended to perform extended focused assessment with sonography for trauma (eFAST) as an initial examination (1B). In hemodynamically stable trauma patients, eFAST can be considered as the initial examination (2B). For the diagnosis of suspected head trauma patients, brain computed tomography (CT) should be performed as an initial examination (1B). Cervical spine CT should be performed as an initial imaging test for patients with suspected cervical spine injury (1C). It is not necessary to perform chest CT as an initial examination in all patients with suspected chest injury, but in cases of suspected vascular injury in patients with thoracic or high-energy damage due to the mechanism of injury, chest CT can be considered for patients in a hemodynamically stable condition (2B). CT of the abdomen is recommended for patients suspected of abdominal trauma with stable vital signs (1B). CT of the abdomen should be considered for suspected pelvic trauma patients with stable vital signs (2B). Whole-body CT can be considered in patients with suspicion of severe trauma with stable vital signs (2B). Magnetic resonance imaging can be considered in hemodynamically stable trauma patients with suspected spinal cord injuries (2B).