• 제목/요약/키워드: Blood physiology

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임상실무에서 필요로 하는 생리학 내용에 대한 연구 (An Analysis of Requisite Knowledge Body of Physiology for Clinical Nursing Practices)

  • 서화숙;이영휘
    • 대한간호학회지
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    • 제29권3호
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    • pp.711-720
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    • 1999
  • The purpose of this study was to define the content of physiological knowledge needed for clinical nursing practices. Subjects of physiology were classified into 15 areas, and each areas was further classified into subareas, resulting in a total of 194 subareas. The degree of importance of each subarea was measured with a 4-point scale. The subjects of this study were 179 nurses of two university hospitals located in Seoul and Inchon. The results were as follows : 1. The areas of physiology necessary for clinical nursing practice as a basic knowledge in the order of importance were : blood, respiratory system and renal physiology, function of the immune system, body fluid and cardiovascular system, body temperature, endocrine physiology and gastrointestinal physiology However, the degree of importance for reproductive physiology, neuro-physiology, energy and metabolism, cell and cell membrane physiology, muscular physiology and special sense was relatively low. 2. The most important content of physiology for all clinical areas in nursing was blood physiology. However, the degree of importance for each physiology area was different depending on clinical areas. 3. Subareas of physiology as a basic knowledge for clinical practice and education in nursing were blood transfusion, blood type, function of red blood cell, white blood cell and platelet, characteristics and function of hemoglobin, composition and function of plasma protein, and mechanism of blood coagulation and anticoagulation. In conclusion, areas of physiology necessary for clinical nursing practice were blood, respiratory system and renal physiology, function of immune, body fluid and cardiovascular system, body temperature, endocrine physiology and gastrointestinal physiology. However, the degree of importance for each physiology area was different depending on clinical areas In nursing.

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자발성(自發性) 고혈압백서(高血壓白鼠)에서 고추(Capsici fructus)의 장기투여(長期投與)가 혈액상(血液像) 및 혈압(血壓)에 미치는 영향(影響) (Effects of Capsici fructus on Blood Figures and Blood Pressure in Spontaneously Hypertensive Rats)

  • 최시현;고상돈;신홍기;김기순
    • The Korean Journal of Physiology
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    • 제17권1호
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    • pp.13-21
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    • 1983
  • The present study was undertaken to investigate effect of feeding hot pepper on the blood pressure and blood figures in SHR. Also studied were effect of hot pepper on plasma electrolyte concentration as well as blood sugar level. Twentytwo SHR at age of 15 weeks were divided into control and CF administered group. And in experimental group hot pepper (1 gm/kg/day) was administered into stomach of each animal by gastric intubation for 8 weeks. The results obtained are as follows: 1) On a day before starting experiment blood pressure(systolic) of the control and CF group were respectively $196.7{\pm}4.7\;mmHg$ and $197.4{\pm}3.9\;mmHg$ while it changed to $207.4{\pm}4.8\;mmHg$ and $227.5{\pm}4.2\;mmHg$ respectively on the last day of experiment. Comparing blood pressures of two groups a significant, though not remarkable, difference was observed. 2) No significant differences in blood figures(RBC, WBC, Hct, and Hb level), concentration of plasma electrolytes($Na^+$ and $K^+$)and blood sugar level were found between control and experimental group.

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산모 혈액과 탯줄 혈액의 연(鉛)함량에 관한 연구 (The Study of Lead Concentration in Maternal and Umbilical Cord Blood)

  • 김동준;김명희;정애순;강신명
    • The Korean Journal of Physiology
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    • 제11권2호
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    • pp.63-66
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    • 1977
  • Motor vehicles are the major source of environmental air pollution through the combustion of lead-containing gasolines. People who live in the areas with heavy traffic usually have the higher blood lead levels. This study was to investigate the lead level between the maternal blood and their infants cord blood. Immediatly after Placental delivary, the sampls of cord blood and maternal venous blood were obtained randomly from 14 infants whose mothers had spent their entire pregnancy in Seoul. Lead concentration was determined by the dithizone method. The results obtained were summarized as follows: 1. Hemoglobin, Hct and RBC were significantly higher in cord blood than in the maternal blood, by 36%, 54.9%, 36.9% respectively. 2. MCV in cord blood was higher than that in maternal blood by 13.8%. But MCH and MCHC were lower than those in maternal blood, by 9.7%, 3.3% respectively. The differences were statistically significant. 3. Lead concentration of cord blood $(23.93\;{\mu}g%)$ was higher than that in maternal blood $(21.93\;{\mu}%)$ by 9.1%.

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만성 실혈성 빈혈자 혈장의 적혈구조혈 작용 (Erythropoietic Activity in Plasma of Chronic Post-hemorrhagic Anemic Men)

  • 김완태;정관옥;김윤선;조용문;정원근;남기용
    • The Korean Journal of Physiology
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    • 제4권1호
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    • pp.55-57
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    • 1970
  • Erythropoietic activity in anemic Plasma of chronic posthemorrhagic anemic men was studied in rats after subcutaneous injection of anemic plasma. Anemic plasma was obtained from blood donors who sold their blood once or twice a week for one or two years to blood bank. Hemoglobin concentrations of 8 blood donors ranged between 4.6 and 8.4 gm/100 ml. Pooled plasma was treated by acidification-boiling method and adjusted to pH 7.5 by adding 0.1 N NaOH. 7ml/kg and 15ml/kg of anemic plasma filtrate was injected to 2 groups of rats respectively for 7 and 8 days. Hemoglobin concentrations, red blood cell counts and reticulocyte counts were observed before and after injection of anemic plasma and no change was induced by the injection. Subsequently, it was concluded that there was no erythropoietin of high titer in the plasma of chronic post-hemorrhagic anemic men.

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Korean Red Ginseng Protects Oxidative Injury Caused by Lead Poisoning

  • Park, Myoung-Soo;Cho, Eun-Jung;Lee, Sang-Ki;Lee, Eun-Ji;Lee, Dae-Sik;Lee, Kwon-Ho;Jeon, Byeong-Hwa
    • Journal of Ginseng Research
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    • 제34권2호
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    • pp.132-137
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    • 2010
  • Lead (Pb) is a metal that is generally considered to be toxic to the cardiovascular system. Pb-exposed animals display the evidence of increased oxidative stress and hypertension. The current study was designed to examine whether Korean red ginseng (KRG) has protective effects against Pb-induced hypertension and oxidative stress in Pb-exposed rats. Male Sprague-Dawley rats were randomly assigned to Pb exposure or control groups. KRG was administered in drinking water at a concentration of 100 mg/kg/day; the control group received plain drinking water. Animals in the Pb-exposed groups were provided with drinking water containing 100 ppm Pb acetate for 12 weeks. Blood pressure, plasma glutathione, blood Pb concentration, and hematologic data, such as red blood cell quantity, were determined. Pb poisoning was assessed by measuring the blood Pb concentration. Pb exposure (100 ppm) for 12 weeks resulted in a marked rise in systolic blood pressure and blood Pb concentration, as well as a significant reduction in plasma glutathione levels and red blood cell quantity. Other measurements, such as heart rate, body weight, and white blood cell quantity, were unchanged. Treatment with KRG significantly lowered blood pressure, raised plasma glutathione and increased red blood cell numbers in Pb-exposed animals; it also had no effect on heart rate, body weight, or white blood cell quantity. However, the elevated blood Pb concentration was not reduced by treatment with KRG (100 mg/kg). Taken together, these data indicate that treatment with KRG in Pb-exposed animals can reduce oxidative stress and lower blood pressure, suggesting that KRG might be protective against Pb-exposed hypertension and oxidative stress.

Role of peripheral vestibular receptors in the control of blood pressure following hypotension

  • Jin, Guang-Shi;Li, Xiang-Lan;Jin, Yuan-Zhe;Kim, Min Sun;Park, Byung Rim
    • The Korean Journal of Physiology and Pharmacology
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    • 제22권4호
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    • pp.363-368
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    • 2018
  • Hypotension is one of the potential causes of dizziness. In this review, we summarize the studies published in recent years about the electrophysiological and pharmacological mechanisms of hypotension-induced dizziness and the role of the vestibular system in the control of blood pressure in response to hypotension. It is postulated that ischemic excitation of the peripheral vestibular hair cells as a result of a reduction in blood flow to the inner ear following hypotension leads to excitation of the central vestibular nuclei, which in turn may produce dizziness after hypotension. In addition, excitation of the vestibular nuclei following hypotension elicits the vestibulosympathetic reflex, and the reflex then regulates blood pressure by a dualcontrol (neurogenic and humoral control) mechanism. In fact, recent studies have shown that peripheral vestibular receptors play a role in the control of blood pressure through neural reflex pathways. This review illustrates the dual-control mechanism of peripheral vestibular receptors in the regulation of blood pressure following hypotension.

Does Inhaled Peppermint Essential Oil Affect Blood Pressure?

  • Park, Sah-Hoon;Kim, Kun-Hee;Park, Jong-Seong
    • 통합자연과학논문집
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    • 제14권3호
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    • pp.95-98
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    • 2021
  • By far, studies on the effect of oral administration of peppermint essential oil on blood pressure are not consistent, increasing or decreasing. And the effect of inhalation of peppermint essential oil on blood pressure was not reported. This study was designed to clarify the effect of peppermint essential oil inhalation on the blood pressure and autonomic nervous system. Blood pressure and heart rate variability (HRV) as an indicator of autonomic nervous system activity were measured. The systolic and diastolic blood pressure was not changed significantly by inhalation of peppermint essential oil. Standard deviation of normal to normal (SDNN), a parameter of total activity of autonomic nervous system also was not changed significantly. High frequency (HF) power level, an indicator of parasympathetic nervous system activity was not changed by peppermint. These results indicate that action mechanism of peppermint essential oil on blood pressure is different by the method of administration, oral or inhalation.

백서의 피부 및 뇌혈류에 미치는 고려홍삼 사포닌 및 비사포닌의 영향 (Effects of Crude Saponin and Saponin-free Fraction of Korea Red Ginseng on the Skin and Cerebral Blood Flow in the Rats)

  • 김신희;김국성;박진봉;한찬수;김광진;김신혜;김세훈;남기열;전병화
    • Journal of Ginseng Research
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    • 제26권3호
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    • pp.132-138
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    • 2002
  • 본 연구에서는 혈류량의 변화를 실시간으로 측정할 수 있는 레이져 도플러 혈류량측정장치를 이용하여 피부혈류 및 뇌혈류량에 미치는 고려홍삼의 사포닌과 비사포닌의 효능을 연구하고자 고려홍삼의 정맥내 복강내 및 구강내로 주입하고 혈류의 변화를 관찰하여 다음과 같은 결론을 얻었다. 고려 홍삼의 사포닌 성분은 피부혈류량에는 영향을 주지 않으나 뇌혈류량을 증가시키는 효능이 있다. 고려 홍삼의 비사포닌 성분은 피부혈류량 및 뇌혈류량에 거의 영향을 주지 않았다. 고려홍삼사포닌에 의한 뇌혈류량의 증가는 복강내 및 경구로 투여할 경우는 관찰할 수 있으나 정맥내로 직접 투여할 경우는 관찰되지 않았다. 이상의 결과를 종합해 볼 때 고려홍삼의 사포닌 성분은 뇌혈류량을 증가시키는 혈류개선작용이 있는 것으로 사료된다.

인공적혈구의 제조 및 이용 (Synthesis and Use of Artificial Red Cells)

  • 하종식;조응행;김구자
    • The Korean Journal of Physiology
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    • 제24권1호
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    • pp.15-26
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    • 1990
  • Hemoglobin was purified from the outdated human red blood cells. Phospholipids were purified from egg yolk and stored in chloroform. The artificial red blood cells (hemosome) were prepared by encapsulation of hemoglobin with phospholipid mutilayer using rotary vacuum evaporator. The shape and size of hemosomes were measured by phase contrast microscope and image analyzer. The function of hemosomes was tested by measuring oxygen dissociation curve using blood gas analyzer. In order to test whether hemosomes are useful as blood substitute they were infused into rats of which one third of total blood were drawn. The results obtained are summarized at followings. 1) Hemosomes were spherical shape and their mean diameter was 0.7 um. 2) Oxygen dissociation curve of hemosomes showed the same figure as that of normal red blood cells. 3) All rats given 1/3 transfusion with hemosomes survived until sacrificed whereas three of four rats given 1/3 transfusion with saline died within 1 hour and the rest of them died within 24 hours.

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동면에 관한 연구 - 혈중 Insulin 농도의 변화 - (Studies on the Physiology of Hibernation - with particular reference to blood level of insulin -)

  • 강복순;강두희
    • The Korean Journal of Physiology
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    • 제6권1호
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    • pp.19-26
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    • 1972
  • Physiological changes in hibernating animals (Manchurian Chipmunk and Hamster) were studied during various phases of the hibernation. The results obtained are summarized as follows. 1. Rectal temperature was declined markedly during hibernation, whereas it remained constant even in exposure of the animals to 0 C environment if the animals were not prepared for hibernation. As body temperature was lowered, heart rate was also markedly reduced as well as respiration and blood pressure. 2. The electrical activity recorded from cortical structure was characterized by replacement of fast wave activity by slow wave activity as body temperature was lowered and became flat at body temperature below 20C. 3. Blood glucose level showed no clear seasonal variations. However, the glycogen contents of the liver were markedly greater during the cold seasons than during the warm seasons. 4. Blood levels of insulin showed no clear seasonal variations.

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