• 한방안이비인후피부과학회지
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• 제22권3호
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• pp.167-177
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• 2009

Objective : Bell's palsy is common and has many clinic study. but bell's palsy sequela is not enough study until now. So this study was evaluated bell's palsy sequela, catamnesis, demonstrator and herb. Methods : From December 2007 to November 2008, patients who visited Dong-seo Oriental Medicine ENT. A clinic study was done on patient who were diagosed bell's palsy, onset 2months over when first visited OPD and treated 3weeks over in Dong-seo Oriental Medicine Cental. To evaluate grade of paralysis, House-Brackman Scale was used. We classified period of improving, sequelas symptom except of facial muscle paralysis, Oriental Medicine diagnosis and herb. Results & Conculsion : 1. The distribution of sex : male 38.88%, female 61.11%. The distribution of age was presented that forty to fifty was the most in 10case(55.55%) 2. The distribution of the region of facial palsy : Rt(55.55%), Lt(44.44%) 3. In distribution of period of first HB-Scale improving : 1~2month was most in 10case(55.55%) 4. In distribution of symptom except of facial muscle paralysis : Dryness of eye 33.33%, Tearling 22.22%, Facial hypoesthesia 22.22%, Mastoid pain 22.22% 5. The distribution of demonstrator : Gi Deficiency and Deficiency of Both Gi and Blood was most in 11case(50%) 6. The distribution of treatment : Palmul-tang and Bojungikki-tang was the most herb in 6case(33.33%) and only acupuncture treatment and rehabilitation treatment was 5case(27.77%).

• 한방재활의학과학회지
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• 제30권4호
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• pp.233-241
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• 2020

This study was performed to evaluate the effect of high frequency therapy applied to the region branching to the external carotid artery for peripheral facial paralysis sequelae. A patient suffering with facial edema due to facial paralysis sequelae had been treated with acupuncture, high frequency therapy on the branch area to the external carotid artery for 7 weeks. The evaluation of clinical outcome was done by degree of swelling by measuring the distance of the face and skin temperature of face through digital infrared thermographic imaging. After treatment, the patient's degree of swelling and the temperature difference between the affected side and normal side was decreased. In addition, the temperature was changed in the entire facial area as well as the treatment point of high frequency therapy. This result shows that acupuncture combined with high frequency therapy at the region branching to the external carotid artery could be an effective way to improve facial blood flow, although further clinical studies will be needed.

• Journal of Acupuncture Research
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• 제26권2호
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• pp.49-58
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• 2009

Objectives : The aim of this study was to investigate whether Doppler ultrasound device is applicable for the evaluation of facial palsy patients. Methods : A total of 25 patients participated in the first assessment and 22 of them finished a follow-up assessment one week later. An assessment comprised of a Minimax-Doppler-K device examination on bilateral acupoints $ST_5$, $SI_{19}$, $ST_2$, and $BL_1$, House-Brackmann grading, and subjective symptom questionnaire. Measurement reliability was assessed and clinically meaningful variations of Doppler measurement values were explored. Results : Doppler ultrasound examination revealed a significant difference of some measurement values between values of the symptom side and the contralateral side, between groups of severe paralysis and moderate paralysis, and between groups of short duration(0-3 weeks) and long duration (3 weeks-5 months) by non-parametric analyses (p<0.05). Several re-examination values showed a significant correlation with the first examination values by Spearman's correlation tests (p<0.05). Conclusions : This study revealed several possibilities for the clinical application of this device. Further validity tests and device improvements for a user's convenience would be helpful for its practical application.

• 대한한의학회지
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• 제18권1호
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• pp.251-266
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• 1997

The results are as follows. 1. Oriental medical terms which express abnormal sensations are Bulin, Mamok, Mamokbulin. 2. Bulin, Oriental medical terminology, was used from Naegyeong's era to the Song Dynasty era and expressed as one of the symptoms in Jungpung(Stroke), Bi syndrome(Obstruction syndrom of Gi and Hyeol), Wi syndrome(Flaccid paralysis of the limbs), Hyeolbi(One of the Bi syndroms). But since the Keum Dynasty era, Mamok or Mamokbulin were more used than Bulin and that was refered as seperated disease. 3. Ma is paresthesia or dysthesia on the skin and the limbs, and the symtoms are not itchy, patients are felt like insect's crawling or bite. Mok is a stubborn symptom , the patients are felt like tree, which don't know pain and itching sensation. And therefore Ma is similar to positive phenomena and Mok is similar to negative phenomena in clinical aspect. 4. Mamok is GiHyeol(Gi is functional activities, Hyeol is blood) and Gyeonglak(Meridian system)'s disease. It's main causes are Giheo(Deficiency of Gi) and Hyeolhel(dificiency of Blood) and inducing tactors are Pung-Han-Seub(pathogenic wind-cold-dump) and Damtak(Phlegm-turbity), Eohyeol(Stagnated blood). 5. Mamok is induced from mononeuritis, multiple mononeuritis, polyneuropathy in the peripheral nervous lesions and also induced from cervical spondylosis, spinal tumour, multiple sclerosis, cerebrospinal vascular disease in central nervous systems.

• 대한한방부인과학회지
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• 제22권1호
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• pp.110-124
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• 2009

Purpose: This study was performed to evaluate anti-thrombotic effect of Jogantanggagambang extract (JGTG). Methods: Blood flow rate through the regular volume of glass tube after the blood was diluted five times with ACD solution. Antithrombotic effect was calculated as a percentage of the experimental animal figure protected from the paralysis of hind legs or death of the mouse that was caused from the administration of platelet aggregation regent. Results: 1. JGTG inhibited the platelet aggregation induced by ADP, epinephrine, collagen and arachidonic acid as compared with the control group. 2. JGTG inhibited pulmonary embolism induced by collagen and epinephrine (inhibitory rate is 37.5%). 3. JGTG increased platelet number and fibrinogen amount significantly and also JGTG shortened PT and APTT significantly as compared with the control group in thrombus model induced by dextran. 4. JGTG increased blood flow rate significantly as compared with the control group in vivo. Conclusion: These results suggest that JGTG can be used for treating various female diseases caused by thrombosis.

• 대한한방부인과학회지
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• 제22권1호
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• pp.79-94
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• 2009

Purpose: This study was performed to evaluate anti-thrombotic effect of Cheongyeoljohyeoltangkamibang extract (CYJHT). Methods: Blood flow rate through the regular volume of glass tube after the blood was diluted five times with ACD soulution. Antithrombotic effect was calculated as a percentage of the experimental animal figure protected from the paralysis of hind legs or death of the mouse that is caused from the administration of platelet aggregation regent. Results: 1. CYJHT inhibited the platelet aggregation induced by ADP, epinephrine, collagen and arachidonic acid as compared with the control group. 2. CYJHT inhibited pulmonary embolism induced by collagen and epinephrine (inhibitory rate is 50%). 3. CYJHT increased platelet number and fibrinogen amount significantly and also CYJHT shortened PT and APTT significantly as compared with the control group in thrombus model induced by dextran. 4. CYJHT increased blood flow rate insignificantly as compared with the control group in vivo. Conclusion: These results suggest that CYJHT can be useful in treating various female diseases caused by thrombosis, such as menstrual pain, menstrual disorder and so on.

• 대한한방부인과학회지
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• 제19권2호
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• pp.1-17
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• 2006

Purpose : The Purpose of this research was to investigate the effects of antithrombotic activities of Haenggyonghonghwatang (HGHHT). Methods : Measured the effect which was given to blood flow rate through the regular volume of glass tube after the blood was diluted five times with ACD soulution. Antithrombotic effect was calculated as a percentage of the experimental animal figure protected from the paralysis of hind legs or death of the mouse that is caused from the administration of platelet aggregation regent. Each of the groups consisted in 8 mice, was divided into Normal, Control, and HGHHT. All of these 3 group were supplied a saline solution and after an hour the control group brought the dextran extravasated blood. Also the HGHHT group was dosed to the experimental mice with Oral Zonde one day before the experiment. After that, the mice were abstained from food. And then we gave a measured amount of it before an hour. Finally, it gave rise to dextran extravasated blood as well as the Control group. Results : The results were obtained as follows. HGHHT inhibited platelet aggregation induced by ADP and epinephrine significantly as compared with the control group. HGHHT showed fibrinolytic activity insignificantly as compared with the control group. HGHHT increased blood flow rate significantly as compared with the control group in vitro, but insignificantly as compared with the control group in vivo. HGHHT inhibited pulmonary embolism induced by collagen and epinephrine(inhibitive rate 50%). HGHHT increased number of platelet, fibrinogen amount and shortened prothrombin time, activated partial thromboplastin time significantly as compared with the control group in thrombus model induced by dextran. Conclusion : HGHHT is effective antithrombotic activity from experimental result.

• 한국임상수의학회지
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• 제40권5호
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• pp.336-340
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• 2023

A dog (2-year old, female, Shih-Tzu) presented with hyperthermia and right-sided facial paralysis characterized by the inability to close the right eye and drooling from the right side of the mouth after H3N2 influenza vaccination [A/Canine/Korea/01/07(H3N2) strain; Caniflu-Max, Bionote, Hwaseong, Gyeonggi-do, ROK]. To determine the cause of the fever and neurological symptoms, physical examination, ophthalmic examination, thoracic and abdominal radiography, abdominal ultrasonography, complete blood counts, serum chemistry values, and electrolyte levels were determined. In addition, Cerebrospinal fluid analysis, antinuclear antibody test, fever of unknown origin polymerase chain reaction (PCR) panel, tick-borne pathogen PCR panel were performed. As a result, hyperthermia, leukocytosis, and elevated C-reactive protein were confirmed. In addition, neurological examination revealed decreased right eyelid reflexes, corneal reflexes, threat response, and facial sensation, it was possible to suspect problems with the trigeminal and facial nerves of the cranial nerve. Magnetic resonance imaging revealed a lesion suggestive of myositis in the right muscular lesion at atlanto-occipital junction level on site of vaccine injection. Therefore, right-sided facial paralysis was tentatively determined to be a secondary cause of nerve damage caused by myositis. The patient was treated with immunosuppressants such as prednisolone and mycophenolate mofetil. After 3 months of immunosuppressant therapy, the patient's symptoms improved.

• 대한임상독성학회지
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• 제18권1호
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• pp.42-46
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• 2020

Tetramine toxicity due to sea snail ingestion is generally mild and has a good prognosis. Tetramine toxicity acts on the acetylcholine receptor, affecting the neuromuscular junction and autonomic nervous system. A 78-year-old female patient visited the emergency room with vomiting and dyspnea after eating sea snails. At the time of admission, the vital signs recorded were 140/80 mmHg-105/min-24/min-36.5℃, and 90% oxygen saturation. Arterial blood test revealed hypercapnia (pCO₂ 58.2 mmHg) and respiratory acidosis (pH 7.213, HCO₃^- 22.5 mmol/L), whereas other blood tests showed no specific findings. Due to decreased consciousness and hypoxia, endotracheal intubation and mechanical ventilation were administered to the patient. Successful weaning was accomplished after 12 hrs, and the patient was discharged without any further complications. Although tetramine toxicity rarely results in acute respiratory failure due to paralysis of the respiratory muscle, caution is required whilst treating the patient.

• 한국한의학연구원논문집
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• 제2권1호
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• pp.40-70
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• 1996

In the literatual study on the cerebral vascular dementia, the results were as follows : 1. Cerebral vascular dementia is so called apoplectic dementia, because it almost occurs after apoplexy, the attack rate has gradually increased by increase of life, so it exert a harmful influence to geriatric diseases. 2. The etiological factors are summarized on deficiency in the heart, kidney, liver(心, 腎, 肝虛), pathogenic wind(豊) pathogenic fire(火) phlegm(痰) and stagnated blood(瘀血) in the oriental medicine, and multiple cerebral infarction, cerebral anemia, decrease of cerebral vascular flow are etiological factors in the occidental medicine. 3. The region of infarction and attack of cerebral vascular dementia have a close connection, and generally the cerebral vascular dementia easily occur in injury of white matter of brain. 4. Symptoms of cerebral vascular dementia are dysphasia, walking disorder, hemiplegia, sensory paralysis, disturbance of memory, judgement, calculation, emotion incontinence, speech impediment, silence or talkative, lower thinking ability and depersonalization, and symptoms are aggravated by stage. 5. Therapeutic herb medicines are Palpungsan(八風散), Baepungsan(排風散), Jinsaanshinhwan(辰砂安神丸), Sabacksan(四白散), Kanghwalyupungsan(姜活愈風散), Woohwangchungshimhwan(牛黃淸心丸), and they are used to dispelling pathogenic wind(祛風), soothe the nerves(安神), dispel pathogenic heat from lung, nourish the blood(淸肺養血).