• Journal of Korean Neurosurgical Society
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• v.65 no.6
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• pp.816-824
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• 2022

Objective : Emergency superficial temporal artery to middle cerebral artery (STA-MCA) anastomosis in patients with large vessel occlusion who fails mechanical thrombectomy or does not become an indication due to over the time window can be done as an alternative for blood flow restoration. The authors planned this study to quantitatively measure the degree of improvement in cerebral perfusion flow using perfusion magnetic resonance imaging (MRI) after bypass surgery and to find out what factors are related to the outcome of the bypass surgery. Methods : For a total of 107 patients who underwent emergent STA-MCA bypass surgery with large vessel occlusion, the National Institute of Health stroke scale (NIHSS), modified Rankin score (mRS), infarction volume, and hypoperfusion area volume was calculated, the duration between symptom onset and reperfusion time, occlusion site and infarction type were analyzed. After emergency STA-MCA bypass, hypoperfusion area volume at post-operative 7 days was calculated and analyzed compared with pre-operative hypoperfusion area volume. The factors affecting the improvement of mRS were analyzed. The clinical status of patients who underwent emergency bypass was investigated by mRS and NIHSS before and after surgery, and changes in infarct volume, extent, degree of collateral circulation, and hypoperfusion area volume were measured using MRI and digital subtraction angiography (DSA). Results : The preoperative infarction volume was median 10 mL and the hypoperfusion area volume was median 101 mL. NIHSS was a median of 8 points, and the last normal to operation time was a median of 60.7 hours. STA patency was fair in 97.1% of patients at 6 months follow-up DSA and recanalization of the occluded vessel was confirmed at 26.5% of patients. Infarction volume significantly influenced the improvement of mRS (p=0.010) but preoperative hypoperfusion volume was not significantly influenced (p=0.192), and the infarction type showed marginal significance (p=0.0508). Preoperative NIHSS, initial mRS, occlusion vessel type, and last normal to operation time did not influence the improvement of mRS (p=0.272, 0.941, 0.354, and 0.391). Conclusion : In a patient who had an acute cerebral infarction due to large vessel occlusion with large ischemic penumbra but was unable to perform mechanical thrombectomy, STA-MCA bypass could be performed. By using time-to-peak images of perfusion MRI, it is possible to quickly and easily confirm that the brain tissue at risk is preserved and that the ischemic penumbra is recovered to a normal blood flow state.

• Korean Journal of Clinical Laboratory Science
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• v.42 no.3
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• pp.155-160
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• 2010

Transcranial Doppler ultrasonography (TCD) allows measurement of blood flow velocity to be made from the basal intracerebral vessels. Blood flow velocity in TCD is highly affected not only by blood vessel diameter, blood flow volume, blood viscosity, but also age and sex. Therefore, the study is focused on the correlation between TCD measurement index and sex/age. Subjects were 214 (male 147, famale 67) who had TCD for headache and stroke evaluations at Dongguk University Ilsan Hospital neurology department from December 2009 to April 2010. Sex did not show significant differences with mean flow velocity (MFV), peak systolic flow velocity (PSFV), end diastolic flow velocity (EDFV), pulsatility index (PI) and resistance index (RI) in middle cerebral artery (MCA). Although age also did not show significant differences with MFV and PSFV, EDFV has statistically decreased with age, and PI and RI has statistically increased with age. In addition, age showed significant correlation with MFV, EDFV, PI and RI, but not with PSFV. Therefore, TCD is definitely correlated with age and sex, so that those influencial factors must be considered when being tested.

• Journal of East-West Nursing Research
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• v.4 no.1
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• pp.66-76
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• 1999

The auricular acupuncture therapy is stimulus treat method that acupuncts or moxibusts at the reaction blood vessel point of various diseases in the upper portion of ear. And this effects from the reaction blood vessel point of an ear to the meridian of whole body system through blood stream. The auricular acupuncture has cured and cared signs and symptoms of many diseases and pathologic problems. And this treatment heels abnormal reactions, nursing focuses so it was examined through literature review that nurses use many portions of the auricular acupuncture in their clinical cares of oriental medicine. This study was proved that the Mae-Chim acupuncture method among various methods of the auricular acupuncture is easy and simple so this method can be used by nurses. And the ear acupuncture site which controls diarrhea, insomnia, migraine, stress vomiting, dyspepsia, high fever, insufficient lactation, bowel dysfunction, menoxenia, anxiety, pruritus and can be found easily and is few the number of acupuncture so the oriental medicine nurses can apply easily to their clients. Therefore the independent oriental medicine nursing intervention can be developed by application of the auricular acupuncture therapy on the oriental medicine clinical nursing and home care in our community.

• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.1
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• pp.34-42
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• 2013

Our study is to review Chinese traditional medicine's journals about the diagnosis and treatment of spasmodic torticollis such as category, syndrome differentiation, acupoints of treatment, and herbal medicine. The journal search was performed using the search engine of China Academic Journal (CAJ) and China Doctor/Master's Dissertation (CDMD) in China National Knowledge Infrastructure (CNKI) from January 1982 to October 2012. Searching key words were the diverse combination of "spasmodic torticollis", "cervical dystonia", "Chinese traditonal medicine", "herbal medicine", "acupuncture", and "syndrome differentiation". The inclusion criteria was all kinds of journals including Chinese traditional medicine approach except for experiment study. The category, syndrome differentiation, acupoints of treatment, and herbal medicine from finally selected journals were extracted and summarized. The fourty-seven Chinese journals were selected finally. The category was divided into wind syndrome, trembling syndrome, convulsive syndrome, and convulsions. The syndrome differentiation was classified as internal stirring of liver wind, yin-blood depletion, invasion of external contraction, uncontrol of governor vessel, internal obstruction of phlegm turbidity, dual deficiency of qi and blood, and blood stasis due to qi stagnation. The combination of acupoints to unblock the meridian and dissipate binds and to tonify governor vessel and repel tremor was mainly used in acupuncture treatment. Galgun-tang or galgun-tanggami was primarily used and the others were the prescriptions to tonify liver and kidney, to calm convulsion, and to dispeling wind-phlegm. We suggests that spasmodic torticollis could be treated using Korean medicine's approach in Korea.

• Journal of Korea Multimedia Society
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• v.22 no.11
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• pp.1280-1287
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• 2019

For developing a wireless implantable device to monitoring the artery variation in real-time. The concept of a special vessel variation measurement capacitive sensor is presented in this paper. The sensor consists of two part; main sensor to measuring the arterial variation, and reference sensor is used to improve the accuracy of the capacitance value variation. Before sensor manufacture, a model of the sensor attached on the artery was designed in 3D to conduct in the FEA simulation to validate the validity and feasibility of the idea. The artery model was designed as layered structures and made of collagenous soft tissues with intima inside, followed by the media and the adventitia. Also, a grease layer was designed in the inner of the arterial wall to imitate the clogged arteries. The simulation was divided into two parts; sensor performance test by changing the diameter of the grease layer, and arterial wall tension test by changing the blood pressure. As the simulation results, the capacitance value measured by the proposed sensor is decreased follow the diameter of the grease increased. Also, large elastic deformation of the arterial wall since changing the blood pressure has been observed.

• Journal of Sensor Science and Technology
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• v.25 no.2
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• pp.138-142
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• 2016

A pulse measurement by tonometry provides useful information for diagnosis, including not only blood pressure and heart rate but also parameters for estimating a condition of the cardiovascular system. Currently, various pulse measurement devices based on the tonometry have been developed. A reliability of these devices is determined by a positioning technic between the sensor and the blood vessel and a controlling technique of the pressurization level. An angle of the sensor for the pulse measurement seems to be highly related with a measured signal, however, the objective studies for this issue have been not published. In this paper, the variation of the pulse signals by tonometry direction was experimentally assessed according to the angle of the sensor. In order for guaranteeing the repeatability of the experiment, we used a pulse generator device, which can generate human pulse signal by using silicon tube and fluid pump, and developed a structure for precise adjustment of the angle and the pressurization level of the sensor. The angle of the sensor was acquired by an inclinometer, which was attached at the opposite side of the sensor. As results, a coefficient of variation (CV) of a maximum amplitude (MA) of the pulse wave was largely increased over the angle range of $-9{\sim}9^{\circ}$. Furthermore, the changes of the pulse shape showed different aspects according to the sign of the angle tilted along the blood vessel. It is expected that the results of this study can be helpful for developing more precise pulse measurement devices based on the tonometry and applying in clinic.

• Proceedings of the KAIS Fall Conference
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• 2004.06a
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• pp.253-257
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• 2004

Platelet aggregation is a complex phenomenon that probably involves several intracellular biochemical pathways. When activated, platelets change shape, aggregate and release the contents of their intracellular granules. The interactions between platelets and blood vessel walls are important in the development of thrombosis and cardiovascular diseases. When blood vessels are damaged, platelet aggregation occurs rapidly to form haemostatic Plugs or arterial thrombi at the sites of vessel injury or in regions where blood flow is disturbed. These thrombi are the source of thromboembolic complications of atherosclerosis, heart attacks, stroke, and peripheral vascular disease. Therefore, the inhibition of platelet function represents a promising approach for the prevention of thrombosis. Plants constitute a rich source of bioactive chemicals such as phenolics, terpenoids and alkaloids. Plant extracts may be an alternative to currently used medicinal source because they constitute a rich source of bioactive chemicals. This study was performed to investigate the antiplatelet activity of extract of Tabebuia impetiginosa Martius ex DC (Taheebo) and find out which fractions to this activity in rabbit platelet. Taheebo was methanol extracted and solvent fractionated in to five fractions (hexane, chloroform, ethylacetate, butanol and water). And each fractions were investigated inhibitory effects on platelet aggregation induced by various agonists using washed rabbit platelets in vitro.

• Archives of Plastic Surgery
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• v.36 no.4
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• pp.489-492
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• 2009

Purpose: Autologous fat injection is ideal for patients who wish to add contour, projection and gross volumization of the aging, atrophic face and is claimed to be a safe procedure. However, there are several case reports in the literature where patients have suffered from acute visual loss and cerebral infarction after facial fat injection. This paper will explore a rare case of vessel related complication, an arteriovenous fistula that occurs after fat injection on forehead. Method: A 28 - year - old female who showed a non - tender, soft $1.0{\times}2.5cm$ sized mass on forehead for 3 weeks. A thrill could be detected on the totuous dilatated vessel - like structure around the mass. She had a fat injection on forehead for soft tissue augmentation 3 months prior to developing the mass. 3 - dimensional brain CT angiography showed arteriovenous fistula. Results: The fistula is totally excised with ligation of feeding vessels. Pathology report showed an atypical vessel which had intimal thickening, myxoid degeneration and thrombus formation. There were no evidences of recurrence at least for 2 months of follow - up. Conclusion: An occurrence of arteriovenous fistula after autologous fat injection is very rare. After perforation of artery and vein by coincidence, blood extravasates with the formation of a hematoma capsule and a pseudocapsule around it. The hematoma capsule would expand and clot would reabsorb resulting in a cavity leading to fistula formation. Other vessel related complications like acute visual loss or cerebral infarction are very severe. Therefore, surgeons should be cautious during facial fat injection to avoid vessel injuries.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.11
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• pp.1219-1227
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• 2011

Due to recent changes in living conditions, people who suffer from vascular disease have been increasing. As a result, several kinds of procedures to treat diseases of the blood vessels are being carried out and the epidemiological analysis and interpretation is needed. In this paper, the mechanical behavior of blood vessels based on hyperelastic model were evaluated. The stress distributions in the arterial walls subjected to both normal blood pressure and high blood pressure are studied along with different opening angles representing as the effect of the residual stress. As a result, when applied to residual stress effects in blood vessels to act maximum stress compared to as the absence of residual stress effect about 50% stresses can be reduced. When high blood pressure was the normal blood pressure acting on the blood vessel wall that twice stress can be confirmed.

• Journal of the Korea Convergence Society
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• v.10 no.2
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• pp.67-73
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• 2019

The blood pressure measurement is calculated as a value corresponding to the pressure of the blood vessel using the pressure from the outside for a long time. Due to the recent miniaturization of measurement equipment and the ICT combination of personal healthcare systems, a system that enables continuous and real-time measurement of blood pressure with a sensor is required. In this study, blood pressure was measured using pulse transit time using Photoplethysmography. In this study, blood pressure was estimated by using systolic blood pressure. And it is possible to make measurement only with PPG itself, which can contribute to making a micro blood pressure measuring device. As a result, systolic blood pressure and PPG's S1-P and P-S2 were used to analyze the possibility of blood pressure estimation.