• 대한한방부인과학회지
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• 제28권4호
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• pp.31-45
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• 2015

Objectives : The purpose of this study is to examine the relationship between the symptoms of primary dysmenorrhea and pulse energy of Chon, Gwan and Cheok. Methods The subjects of this study who had certain range of dysmenorrhea symptom. The degree of dysmenorrhea were assessed by Visual Analog Scale (VAS), Multidimensional Verbal Rating Scale (MVRS), Cox Menstrual Symptom Scale (CMSS) and measured by 3D Blood Pressure Pulse Analyzer(3D-MAC) tests at menstruation start date. Data analysis included descriptive statistics and multiple linear regression using the SPSS/WIN 18.0 program. Results : The induced results are as follows;The induced results are as follows 1. There were no significant relationship between the pulse energy and the sum values of VAS, MVRS and checking part of severity of CMSS. 2. The frequency domain of CMSS were significantly associated with pulse energy. 3. In linear regression models, the model of Left Chon had the especially highest value of explanatory power. (R ² = 0.517) Conclusions : The pulse energy changes are related to the symptoms of primary dysmenorrhea.

• 한국융합학회논문지
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• 제10권11호
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• pp.209-215
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• 2019

디지털헬스케어에서 가장 중요한 개인 건강관리는 주로 만성질환자에게 매우 중요한 문제이다. 따라서 실시간 건강관리를 위한 간단한 웨어러블 디바이스 개발이 중요하다. 기존 혈압 추정 웨어러블 디바이스는 PPG 특성을 통해 PTT를 분석하여 혈압 추정 알고리즘을 제안하고 있다. 그러나 PPG의 재현성과 여러 가지 PTT의 적용여부와 측정자의 신체적 차이에서 발생되는 변수 등 알고리즘의 영향인자가 사실 매우 복잡하다. 따라서 본 연구에서는 PTT와 SBP, DBP의 상관관계를 분석하고, 다바이스 소형화를 위해 PPG센서만을 사용하게 설계하였다. 제안된 혈압 추정 알고리즘은 PPG간의 차이와 심박수, 개인적인 변수 등을 고려하였다. 또한 기존 의료기관에서 사용하는 공기가압방식의 결과값과 개발된 알고리즘을 통해 추정된 혈압값과 비교를 통해 확인하였다.

• 대한한의학회지
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• 제45권1호
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• pp.251-256
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• 2024

Objectives: The purpose of this study was to report the short-term blood pressure-lowering effects observed in a patient with malignant hypertension through slow breathing maneuver with heart rate variability(HRV) biofeedback. Methods: Biofeedback sessions, totaling 13, each lasting 10 minutes, were administered. Blood pressure was measured pre and post-treatment, as well as thrice daily at 10 am, 4 pm, and 8 pm. Systolic blood pressure(SBP), diastolic blood pressure(DBP), and pulse rate were recorded for comparative analysis. Results: Before biofeedback, the average SBP, DBP, and pulse rate were 227.2±18.3, 135.2±11.0, and 104.4±5.3, respectively. Immediately post-biofeedback, these values changed to 213.7±15.2, 126.9±8.5, and 99.2±3.6. However, sustained long-term blood pressure reduction was not observed. Conclusions: The findings suggest that biofeedback therapy induces a short-term reduction in blood pressure in cases of malignant hypertension, potentially associated with autonomic nervous system regulation. Integrating biofeedback with other Korean medicine treatments, such as acupuncture or moxibustion, may offer a comprehensive approach for managing malignant hypertension.

• 대한의생명과학회지
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• 제26권1호
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• pp.28-36
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• 2020

High blood pressure (HTN) is a condition in which blood pressure is kept higher than normal. Blood pressure trait measures systolic blood pressure (SBP) which is the highest pressure and diastolic blood pressure (DBP) which is the lowest blood pressure. Pulse pressure (PP) is the difference between systolic and diastolic blood pressure. Hypertension is known as a disease caused by the interaction of the environment and genetic factors. To date, studies have been conducted to find genes associated with hypertension. Genome-Wide Association Study (GWAS) analysis using European data from the UK Biobank reported new 535 loci were associated with blood pressure trait. Among them, 12 genes have been reported to have a significant correlation with SBP, DBP and PP. In the study, 12 genes polymorphisms were extracted based on KARE (Korean association resource) and then we performed linear regression of blood pressure trait. As a result, 6 SNPs of the 3 genes (rs12355413 and rs11006736 of ARMC4, rs2290883, rs2290884 and rs11039014 of LRP4, rs7234941 of BCL2) showed statistically significant correlation (P<0.05) with blood pressure trait. Of the 3 genes, 6 SNPs in 2 genes (rs9651357, rs12355413, rs11006736, rs1889522 of ARMC4 and rs4987774, rs7234941 of BCL2) showed significant correlation with hypertension. These results suggest that genetic polymorphisms of ARMC4, LRP4 and BCL2 genes are associated with blood pressure traits and hypertension in Korean population. Moreover, we expected to help understand the pathogenesis of hypertension.

• 전기학회논문지
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• 제57권6호
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• pp.1095-1101
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• 2008

The desirable method to diagnose abnormal blood pressure is to measure and manage blood pressure continuously and regularly. However, the sphygmomanometers that are based on a cuff have faults in that they can not measure the blood pressure continuously and they cause an unpleasant feeling. Therefore, it is essential to develop a new measuring method that causes no pain and that can obtain blood pressure continuously without any unpleasant feeling. Thus, we propose here a regression method to estimate the systolic blood pressure by using the PTTL(pulse transit time on leg) with some body parameters which are chosen from the relational analysis with systolic blood pressure. The data we use to make the regression model were obtained in triplicate from each of 50 males who were from 18 to 35 years. And we made estimation experiments of blood pressure on 10 males who did not take part in the making the regression model. According to the results, the proposed method showed a mean error of 4.00 mmHg and the standard variance was 2.45 mmHg. When we comparing the results of the proposed method with the rule of American National Standards Institute of the Association of the Advancement of Medical Instruments(ANSI/AAMI), the results satisfied the rule of a mean error less than 5 mmHg and a standard variance less than 8 mmHg. Therefore we were able to validate the usefulness of the proposed method.

• 대한불안의학회지
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• 제9권2호
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• pp.121-127
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• 2013

Objective : Several studies have reported the association between posttraumatic stress disorder (PTSD) and hypertension (HTN). The aim of this study was to evaluate the impact of PTSD symptoms on blood pressure. Methods : Korean veterans of the Vietnam War with (n=62) or without PTSD (n=87) participated in this study. The clinician administered PTSD scale (CAPS) and alcohol use disorder identification test (AUDIT) were applied. Blood pressure, pulse rate, risk factors of HTN and demographic data of the subjects were collected. Effects of potential explanatory variables on HTN were analyzed with logistic regression. Results : Diastolic blood pressure was significantly higher in PTSD group (p=0.015). However, PTSD subjects showed significantly lower pulse rate than non-PTSD subjects (p=0.004). Logistic regression analysis showed that avoidance symptom might be a predictor for hypertension (OR=1.065, p=0.030). Conclusion : These results suggest that PTSD, especially avoidance symptom, might be a risk factor on HTN in the elderly with PTSD. Further studies are needed to evaluate the change of blood pressure according to the clinical improvement of PTSD.

• 대한약침학회지
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• 제18권2호
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• pp.33-41
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• 2015

Objectives: The present study evaluated the effects of sa-am acupuncture (SAA) simpo-jeongkyeok (SPJK) treatment on the blood pressure (BP), pulse rate (PR), and body temperature (BT) of patients with hwa byung (HB). Methods: This patient assessor blind, randomized, placebo controlled trial included 50 volunteers, divided randomly into two groups. The treatment group underwent SPJK (PC9, LR1, PC3, KI10) while the control (sham) group received minimal needle insertion at non acupoints. The BP in both arms, PR, and BT at several acupoints were measured before and after treatment at the $1^{st}$, $2^{nd}$, $3^{rd}$, and $4^{th}$ visits and before treatment at the follow-up visit. We analyzed data by using the repeated measured analysis of variance (RM ANOVA), Mann-Whitney U, and wilcoxon signed rank tests; differences at P < 0.05 were considered significant. Results: No significant differences in the systolic blood pressure (SBP), diastolic blood pressure (DBP) and PR between the treatment and control group were observed at each visit. However, the decrease in the SBP for the treatment group before and after each visit was significantly higher than it was in the control group. The SBP in both arms in the treatment group was decreased between visits 1 and 2, 1 and 3, 1 and 4, and 1 and follow-up. The DBP in both arms and in the right arm between visits 1 and 3 in the treatment group showed decreases. A minimal BT increase for treatment at CV06 and CV12 and a minimal BT decrease for treatment at CV17 and (Ex) Yintang were found. Patients in the treatment group who visited more frequently experienced a greater decrease in the PR, but that effect was not maintained. Conclusion: The results suggest that SAA SPJK treatment has instant positive effects on the BP, PR, and BT in patients with HB, but the effects on the BP and PR are not maintained.

• 대한기계학회논문집A
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• 제32권5호
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• pp.444-450
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• 2008

The conventional studies of the aging effect on cardio-vascular system are mostly obtained from human experiences and can only provide local information. In this study, the effect of fatigue fracture of arterial wall on the blood pressure was investigated by hemodynamic analysis. The aging process was simulated with three stages. The pulse wave velocity increased with age. The systolic blood pressure increases consistently but diastolic blood pressure decreases with age. The simulated results show in good accordance with the clinical ones.

• 한국인터넷방송통신학회논문지
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• 제18권4호
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• pp.161-168
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• 2018

고혈압은 현대 주요 성인병이며 기존의 혈압계로는 실시간 혈압 측정 및 원격 모니터링이 어렵다. 그러나 실시간 혈압 모니터링 u-헬스케어 시스템은 효과적인 건강관리가 가능하도록 해준다. 실시간 혈압 모니터링을 위해 본 논문에서는 손목형 혈압계, 스마트폰 및 u-헬스케어 서버로 구성된 실시간 혈압 모니터링 u-헬스케어 시스템의 구조를 제시한다. 그리고 손목형 혈압계의 하드웨어 설계를 위한 주요 핵심 기능인 맥파검출 아날로그 회로 구성과 손목형 혈압계를 구성하는 디지털 하드웨어 구성을 제시한다. 또한 이들 하드웨어 시스템을 동작시키는 소프트웨어 개발을 위한 UML 분석방법과 소프트웨어 설계를 위한 플로우차트와 화면 설계를 보여준다. 따라서 본 논문에서 제시한 설계방법은 실시간 모니터링 u-헬스케어 시스템 구현에 매유 유용하게 활용될 수 있을 것으로 기대된다.

• 한국산업보건학회지
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• 제24권2호
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• pp.137-145
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• 2014

Objectives: The study examines the relation between urinary arsenic concentration and blood pressure, which is a risk factor of cardiovascular disease. Materials: In this study, the urinary arsenic concentration, history of diagnosed disease, and blood pressure of 782 local residents in Gwangyang, Yeosu, and Hadong regions from May 2007 to July 2007. Results: The urinary arsenic concentration of total participants was $9.06{\mu}g/g-ct$. The logistic regression analysis of medical diagnosed history and urinary arsenic concentration, showed statistically significance (p<0.05) of high urinary arsenic concentration in participants with diagnosed hypertension. In addition, diagnosed hypertension it was observed that the high blood pressure was related with the pulse pressure. Conclusions: The arsenic concentration level was low in this study, but the exposure to low levels of arsenic has an effect on hypertension. Also, hypertension is related to pulse pressure and mean arterial blood pressure as well as being risk factor of cardiovascular disease. Therefore, close supervision of low -level arsenic exposure is needed.